vanillin has been researched along with Inflammation in 15 studies
Vanilla: A plant genus of the family ORCHIDACEAE that is the source of the familiar flavoring used in foods and medicines (FLAVORING AGENTS).
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vanillin has been shown to protect dopaminergic neurons, but the mechanism is still unclear." | 5.46 | Vanillin Protects Dopaminergic Neurons against Inflammation-Mediated Cell Death by Inhibiting ERK1/2, P38 and the NF-κB Signaling Pathway. ( Chen, GX; Fu, SP; Huang, BX; Liu, D; Liu, DF; Liu, JX; Ren, WZ; Wang, W; Xu, SY; Yan, X; Zhang, XY, 2017) |
| "Vanillic acid (1) is a flavoring agent found in edible plants and fruits." | 5.42 | Vanillic Acid Inhibits Inflammatory Pain by Inhibiting Neutrophil Recruitment, Oxidative Stress, Cytokine Production, and NFκB Activation in Mice. ( Baracat, MM; Calixto-Campos, C; Carvalho, TT; Casagrande, R; Fattori, V; Georgetti, SR; Hohmann, MS; Manchope, MF; Pinho-Ribeiro, FA; Verri, WA; Zarpelon, AC, 2015) |
| "Increasing evidence supports vanillin and its analogs as potent toll-like receptor signaling inhibitors that strongly attenuate inflammation, though, the underlying molecular mechanism remains elusive." | 4.31 | A small molecule potent IRAK4 inhibitor abrogates lipopolysaccharide-induced macrophage inflammation in-vitro and in-vivo. ( Choudhary, SA; Chouhan, R; Das, SK; Dasgupta, S; Jha, AN; Manna, D; Mazumder, S; Pal, D; Pant, R; Patra, D; Prusty, BM; Sinha, A; Tikoo, K, 2023) |
| "Vanillin is a phenolic aldehyde, widely used as a flavoring agent in the food, pharmaceutical, and cosmetics industries." | 2.61 | Therapeutic Potential of Vanillin and its Main Metabolites to Regulate the Inflammatory Response and Oxidative Stress. ( Barboza, JN; Bezerra-Filho, CSM; de Sousa, DP; Ismail, NSM; Sabry, P; Souza, MTS, 2019) |
| "Endometriosis is an estrogen-dependent chronic inflammatory gynecological disease defined by the presence of endometrial glands and mesenchyme outside the uterine cavity, named ectopic endometrium." | 1.91 | Vanillin prevents the growth of endometriotic lesions through anti-inflammatory and antioxidant pathways in a mouse model. ( Kang, JW; Liang, C; Liu, YN; Lu, L; Song, SS; Su, RW; Wei, SW; Xu, QX; Zhang, H; Zhang, Y, 2023) |
| "Vanillin has been shown to protect dopaminergic neurons, but the mechanism is still unclear." | 1.46 | Vanillin Protects Dopaminergic Neurons against Inflammation-Mediated Cell Death by Inhibiting ERK1/2, P38 and the NF-κB Signaling Pathway. ( Chen, GX; Fu, SP; Huang, BX; Liu, D; Liu, DF; Liu, JX; Ren, WZ; Wang, W; Xu, SY; Yan, X; Zhang, XY, 2017) |
| "Mice treated with o-vanillin exhibited reduced TLR2-induced inflammation." | 1.42 | Inhibition of TLR2 signaling by small molecule inhibitors targeting a pocket within the TLR2 TIR domain. ( Chauhan, J; Dyson, T; Fletcher, S; Greene, S; Laird, MH; MacKerell, AD; Mistry, P; Schwarz, RS; Snyder, GA; Toshchakov, VY; Vogel, SN; Xiao, TS, 2015) |
| "Vanillic acid (1) is a flavoring agent found in edible plants and fruits." | 1.42 | Vanillic Acid Inhibits Inflammatory Pain by Inhibiting Neutrophil Recruitment, Oxidative Stress, Cytokine Production, and NFκB Activation in Mice. ( Baracat, MM; Calixto-Campos, C; Carvalho, TT; Casagrande, R; Fattori, V; Georgetti, SR; Hohmann, MS; Manchope, MF; Pinho-Ribeiro, FA; Verri, WA; Zarpelon, AC, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 10 (66.67) | 24.3611 |
| 2020's | 4 (26.67) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Choudhary, SA | 1 |
| Patra, D | 1 |
| Sinha, A | 1 |
| Mazumder, S | 1 |
| Pant, R | 1 |
| Chouhan, R | 1 |
| Jha, AN | 1 |
| Prusty, BM | 1 |
| Manna, D | 1 |
| Das, SK | 1 |
| Tikoo, K | 1 |
| Pal, D | 1 |
| Dasgupta, S | 1 |
| Elseweidy, MM | 2 |
| Ali, SI | 1 |
| Shaheen, MA | 1 |
| Abdelghafour, AM | 1 |
| Hammad, SK | 1 |
| Liu, YN | 1 |
| Kang, JW | 1 |
| Zhang, Y | 1 |
| Song, SS | 1 |
| Xu, QX | 1 |
| Zhang, H | 1 |
| Lu, L | 1 |
| Wei, SW | 1 |
| Liang, C | 1 |
| Su, RW | 1 |
| Bisson, DG | 1 |
| Sheng, K | 1 |
| Kocabas, S | 1 |
| Krock, E | 1 |
| Teles, A | 1 |
| Saran, N | 1 |
| Ouellet, JA | 1 |
| Haglund, L | 1 |
| Askar, ME | 1 |
| Elswefy, SE | 1 |
| Shawky, M | 1 |
| Kim, ME | 1 |
| Na, JY | 1 |
| Park, YD | 1 |
| Lee, JS | 1 |
| Chen, H | 1 |
| Zheng, J | 1 |
| Ma, J | 1 |
| Bezerra-Filho, CSM | 1 |
| Barboza, JN | 1 |
| Souza, MTS | 1 |
| Sabry, P | 1 |
| Ismail, NSM | 1 |
| de Sousa, DP | 1 |
| Kwon, J | 1 |
| Kim, J | 1 |
| Park, S | 1 |
| Khang, G | 1 |
| Kang, PM | 1 |
| Lee, D | 1 |
| Mistry, P | 1 |
| Laird, MH | 1 |
| Schwarz, RS | 1 |
| Greene, S | 1 |
| Dyson, T | 1 |
| Snyder, GA | 1 |
| Xiao, TS | 1 |
| Chauhan, J | 1 |
| Fletcher, S | 1 |
| Toshchakov, VY | 1 |
| MacKerell, AD | 1 |
| Vogel, SN | 1 |
| Grilli, E | 1 |
| Tugnoli, B | 1 |
| Passey, JL | 1 |
| Stahl, CH | 1 |
| Piva, A | 1 |
| Moeser, AJ | 1 |
| Calixto-Campos, C | 1 |
| Carvalho, TT | 1 |
| Hohmann, MS | 1 |
| Pinho-Ribeiro, FA | 1 |
| Fattori, V | 1 |
| Manchope, MF | 1 |
| Zarpelon, AC | 1 |
| Baracat, MM | 1 |
| Georgetti, SR | 1 |
| Casagrande, R | 1 |
| Verri, WA | 1 |
| Yan, X | 1 |
| Liu, DF | 1 |
| Zhang, XY | 1 |
| Liu, D | 1 |
| Xu, SY | 1 |
| Chen, GX | 1 |
| Huang, BX | 1 |
| Ren, WZ | 1 |
| Wang, W | 1 |
| Fu, SP | 1 |
| Liu, JX | 1 |
| Park, SH | 1 |
| Sim, YB | 1 |
| Choi, SM | 1 |
| Seo, YJ | 1 |
| Kwon, MS | 1 |
| Lee, JK | 1 |
| Suh, HW | 1 |
1 review available for vanillin and Inflammation
| Article | Year |
|---|---|
Therapeutic Potential of Vanillin and its Main Metabolites to Regulate the Inflammatory Response and Oxidative Stress.
Topics: Animals; Antioxidants; Benzaldehydes; Humans; Inflammation; Molecular Docking Simulation; Molecular | 2019 |
1 trial available for vanillin and Inflammation
| Article | Year |
|---|---|
Impact of dietary organic acids and botanicals on intestinal integrity and inflammation in weaned pigs.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Benzaldehydes; Caco-2 Cells; Citri | 2015 |
13 other studies available for vanillin and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
A small molecule potent IRAK4 inhibitor abrogates lipopolysaccharide-induced macrophage inflammation in-vitro and in-vivo.
Topics: Animals; Inflammation; Interleukin-1 Receptor-Associated Kinases; Lipopolysaccharides; Macrophages; | 2023 |
Vanillin and pentoxifylline ameliorate isoproterenol-induced myocardial injury in rats
Topics: Animals; Inflammation; Isoproterenol; Myocardial Infarction; Myocardium; Oxidative Stress; Pentoxify | 2023 |
Vanillin prevents the growth of endometriotic lesions through anti-inflammatory and antioxidant pathways in a mouse model.
Topics: Adult; Animals; Anti-Inflammatory Agents; Antioxidants; Endometriosis; Female; Humans; Inflammation; | 2023 |
Toll-like receptor involvement in adolescent scoliotic facet joint degeneration.
Topics: Adolescent; Adult; Alarmins; Benzaldehydes; Chondrocytes; Extracellular Matrix; Female; Gene Express | 2020 |
Vanillin as a new modulator candidate for renal injury induced by cisplatin in experimental rats.
Topics: Animals; Benzaldehydes; Cisplatin; Fibrosis; Inflammation; Kidney; Male; NF-kappa B; Rats; Tumor Nec | 2017 |
Anti-Neuroinflammatory Effects of Vanillin Through the Regulation of Inflammatory Factors and NF-κB Signaling in LPS-Stimulated Microglia.
Topics: Benzaldehydes; Cyclooxygenase 2; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression | 2019 |
Vanillin ameliorates changes in HIF-1α expression and neuronal apoptosis in a rat model of spinal cord injury.
Topics: Animals; Apoptosis; Benzaldehydes; Disease Models, Animal; Gene Expression; Hypoxia-Inducible Factor | 2019 |
Inflammation-responsive antioxidant nanoparticles based on a polymeric prodrug of vanillin.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Benzaldehydes; Biomarkers; Dioxanes; Hydrogen Perox | 2013 |
Inhibition of TLR2 signaling by small molecule inhibitors targeting a pocket within the TLR2 TIR domain.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Benzaldehydes; Drug Design; Drug Evaluation, Precli | 2015 |
Vanillic Acid Inhibits Inflammatory Pain by Inhibiting Neutrophil Recruitment, Oxidative Stress, Cytokine Production, and NFκB Activation in Mice.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Benzaldehydes; Benzoquinones; Carrageen | 2015 |
Vanillin Protects Dopaminergic Neurons against Inflammation-Mediated Cell Death by Inhibiting ERK1/2, P38 and the NF-κB Signaling Pathway.
Topics: Animals; Benzaldehydes; Cell Death; Cell Line; Cytokines; Dopaminergic Neurons; Inflammation; Inflam | 2017 |
Antinociceptive profiles and mechanisms of orally administered vanillin in the mice.
Topics: Administration, Oral; Analgesics; Animals; Benzaldehydes; Disease Models, Animal; Dose-Response Rela | 2009 |