vanicoside-b and Neoplasms

vanicoside-b has been researched along with Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for vanicoside-b and Neoplasms

Article	Year
Cancer chemopreventive activity of phenylpropanoid esters of sucrose, vanicoside B and lapathoside A, from Polygonum lapathifolium. Cancer letters, 2001, Nov-28, Volume: 173, Issue:2 To search for cancer chemopreventive agents from natural resources, many phytochemicals have been screened using the in vitro synergistic assay indicated by the inhibitory effects on the induction of Epstein-Barr virus early antigen (EBV-EA) by 12-O-tetradecanoylphorbol-13-acetate (TPA). Two phenylpropanoid esters of sucrose, vanicoside B and lapathoside A, were isolated from the aerial part of Polygonum lapathifolium as inhibitors on the EBV-EA induction. These compounds also exhibited significant anti-tumor-promoting effects on mouse two-stage skin carcinogenesis induced by 7,12-dimethylbenz[a]anthracene (DMBA, as an initiator) and TPA as a promoter. Further, vanicoside B exhibited the remarkable inhibitory effect on two-stage carcinogenesis test of mouse skin tumors initiated with an NO donor, NOR-1. Topics: Animals; Anticarcinogenic Agents; Cinnamates; Disaccharides; Dose-Response Relationship, Drug; Esters; Female; Mice; Mice, Inbred ICR; Models, Chemical; Neoplasms; Nitric Oxide Donors; Sucrose; Tetradecanoylphorbol Acetate; Time Factors	2001

Article

Year

Cancer chemopreventive activity of phenylpropanoid esters of sucrose, vanicoside B and lapathoside A, from Polygonum lapathifolium.

Cancer letters, 2001, Nov-28, Volume: 173, Issue:2

To search for cancer chemopreventive agents from natural resources, many phytochemicals have been screened using the in vitro synergistic assay indicated by the inhibitory effects on the induction of Epstein-Barr virus early antigen (EBV-EA) by 12-O-tetradecanoylphorbol-13-acetate (TPA). Two phenylpropanoid esters of sucrose, vanicoside B and lapathoside A, were isolated from the aerial part of Polygonum lapathifolium as inhibitors on the EBV-EA induction. These compounds also exhibited significant anti-tumor-promoting effects on mouse two-stage skin carcinogenesis induced by 7,12-dimethylbenz[a]anthracene (DMBA, as an initiator) and TPA as a promoter. Further, vanicoside B exhibited the remarkable inhibitory effect on two-stage carcinogenesis test of mouse skin tumors initiated with an NO donor, NOR-1.

Topics: Animals; Anticarcinogenic Agents; Cinnamates; Disaccharides; Dose-Response Relationship, Drug; Esters; Female; Mice; Mice, Inbred ICR; Models, Chemical; Neoplasms; Nitric Oxide Donors; Sucrose; Tetradecanoylphorbol Acetate; Time Factors

2001