vanadates has been researched along with Alloxan Diabetes in 216 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (6.94) | 18.7374 |
| 1990's | 104 (48.15) | 18.2507 |
| 2000's | 72 (33.33) | 29.6817 |
| 2010's | 22 (10.19) | 24.3611 |
| 2020's | 3 (1.39) | 2.80 |
| Authors | Studies |
|---|---|
| Bottini, RCR; da Cunha, JM; de Nigro, TP; de Souza, SW; Jesus, CHA; Manica, GCM; Missina, JM; Nunes, GG; Picheth, G; Rego, FGM; Valdameri, G | 1 |
| El-Shafey, ES; Elsherbiny, ES | 1 |
| Chen, K; Jia, H; Liu, Y; Wei, Y; Yin, P | 1 |
| Bhattacharya, S; Chatterjee, SK; Chattopadhyay, D; Chaudhuri, MK; Das, S; Majumdar, SS; Mukherjee, S; Mukhopadhyay, S; Sarkar, S; Talukdar, D | 1 |
| Al-Omar, MA; Al-Wasidi, AS; AlKahtani, HM; Bhat, MA; Naglah, AM; Refat, MS | 1 |
| Ali, S; Basir, SF; Upreti, J | 1 |
| Aranda, P; Gómez-Aracena, J; Llopis, J; López-Chaves, C; López-Jurado, M; Montes-Bayón, M; Sánchez-González, C; Sanz-Medel, A; Trenzado, CE | 1 |
| Moroki, T; Tsubura, A; Yasui, H; Yoshikawa, Y; Yoshizawa, K | 1 |
| El-Megharbel, SM; Hamza, RZ; Refat, MS | 1 |
| Baquer, NZ; Kumar, N; Kumar, P; Kumar, V; Taha, A | 1 |
| Guo, Y; Jie, X; Liu, Y; Wang, J; Xue, C; Zhang, X | 1 |
| Cong, XQ; Li, Y; Liu, Y; Piao, MH; Xie, L | 1 |
| Brambila-Colombres, E; Diaz-Fonseca, A; Flores-Hernandez, JÁ; González-Vergara, E; Pérez-Benítez, A; Sánchez-Lara, E; Treviño, S; Velázquez-Vázquez, D | 1 |
| Galvez, J; Llopis, J; Lopez-Chaves, C; Montes-Bayon, M; Moreno, L; Nebot, E; Pietschmann, P; Rodriguez-Nogales, A; Sanchez-Gonzalez, C; Sanz-Medel, A | 1 |
| Cai, HX; Li, DW; Wang, K; Xia, Q; Xia, ZL; Yang, XD; Zhang, L; Zhang, Y; Zhao, XM | 1 |
| Bolkent, S; Demirci, TB; Tunali, S; Ulküseven, B; Yanardag, R | 1 |
| Baruah, B; Crans, DC; Ding, W; Li, M; Smee, JJ; Willsky, GR | 1 |
| Liu, WP; Meng, ZH; Xie, MJ; Yan, SP; Yang, XD | 1 |
| Clark, TA; Ganguly, PK; Heyliger, CE; Maddaford, TG; Pierce, GN; Tappia, PS | 1 |
| Cao, C; Cui, H; Guo, J; Liu, S; Zhang, Y; Zhao, Y | 1 |
| Wang, K; Wei, Y; Yang, X; Zhang, C; Zhao, P | 1 |
| Guo, J; Li, P; Liu, Z; Tang, H; Zhao, D | 1 |
| Batlle, AM; Davio, C; Gerez, EN; Oliveri, LM | 1 |
| Bermudez-Peña, C; Guerrero-Romero, F; Llopis, J; Montes-Bayon, M; Sanchez-Gonzalez, C; Sanz-Medel, A; Trenzado, CE | 1 |
| Aguilar, F; Clark, TA; Edel, AL; Heyliger, CE; Junaid, A; Kim, HK; Kopilas, M; Merchant, M; Pierce, GN; Smyth, DD; Thliveris, JA | 1 |
| Baquer, NZ; Kale, RK; Kumar, P; McLean, P; Taha, A | 1 |
| Mustafa, S | 1 |
| El-Shenawy, NS; Fakihi, FH; Refat, MS | 1 |
| Sakurai, H; Takino, T; Tamura, A; Yasui, H | 1 |
| Baquer, NZ; Genet, S; Kale, RK | 2 |
| Brownsey, RW; Marzban, L; McNeill, JH; Rahimian, R | 1 |
| Dabroś, W; Dziga, D; Kordowiak, AM | 2 |
| Baquer, NZ; Thakran, S | 1 |
| Li, XR; Shen, LW; Xu, MZ; Xu, W; Zhang, AZ | 2 |
| Aleeva, GN; Gallyamov, RM; Gosmanov, AR; Khafiz'yanova, RKh; Latypov, RS; Minnebaev, MM | 1 |
| Huisamen, B | 1 |
| Ikeda, K; Izumi, T; Masuda, T; Matsuyama, N; Noda, C; Sato, K; Shimohama, T | 1 |
| Kandaswamy, M; Narayanan, V; Ramachandran, B; Subramanian, S | 1 |
| Battell, ML; Bhanot, S; McNeill, JH; Orvig, C; Yuen, VG | 1 |
| Fugono, J; Sakurai, H; Yasui, H | 1 |
| Adachi, Y; Inohara, T; Kawabe, K; Sakurai, H; Takada, J; Yasui, H | 1 |
| Abella, A; Carpéné, C; Marti, L; Palacín, M; Testar, X; Zorzano, A | 2 |
| Bour, S; Carpéné, C; Marq, P; Monje, MC; Morin, N; Nepveu, F; Prévot, D; Subra, C; Valet, P; Visentin, V | 1 |
| Bamezai, RN; Baquer, NZ; Basir, SF; Mohamad, S; Mohammad, S; Taha, A | 1 |
| Chiles, J; McNeill, JH; Orvig, C; Thompson, KH; Tse, J; Yuen, VG | 1 |
| Lv, WL; Zhang, H; Zhang, Q; Zhang, X; Zhong, XY | 1 |
| Eddouks, M; Lemhadri, A; Michel, JB | 1 |
| Eddouks, M; Maghrani, M | 1 |
| Baquer, NZ; Gupta, BL; Preet, A | 1 |
| Baquer, NZ; Moorthy, K; Yadav, UC | 2 |
| Clark, TA; Edel, AL; Goel, DP; Heyliger, CE; Pierce, GN | 1 |
| Kandaswamy, M; Narayanan, V; Ramachandran, B; Ravi, K; Subramanian, S | 1 |
| Böhmerle, K; Martins, C; McNeill, JH; Orvig, C; Polishchuk, E; Thompson, KH; Toleikis, P; Tse, J; Yuen, V | 1 |
| McNeill, JH; Orvig, C; Patrick, BO; Pink, M; Saatchi, K; Thompson, KH; Yuen, VG | 1 |
| Dabros, W; Drozdowska, E; Goc, A; Kordowiak, AM; Turyna, B | 1 |
| Aikawa, J; Fernandes, LC; Hirabara, SM; Lissa, MD; Lopes, MC; Nogata, C; Nunes, EA; Tanhoffer, RA; Tchaikovski, OJ; Yamazaki, RK | 1 |
| Martins, C; McNeill, JH; Mohammadi, K; Orvig, C; Patrick, BO; Polishchuk, E; Storr, T; Thompson, KH; Yuen, VG | 1 |
| Baquer, NZ; Gupta, BL; Preet, A; Siddiqui, MR; Yadava, PK | 1 |
| Baquer, NZ; Basir, SF; Hussain, ME; Moorthy, K; Siddiqui, MR; Taha, A | 1 |
| Boucher, J; Bour, S; Carpéné, C; Ordener, C; Parini, A; Prévot, D; Valet, P; Visentin, V | 1 |
| Battell, ML; Facchini, DM; Grynpas, MD; McNeill, JH; Yuen, VG | 1 |
| Bamezai, RN; Baquer, NZ; Mohammad, S; Taha, A | 1 |
| Adachi, Y; Katoh, A; Saito, R; Sakurai, H; Wakasugi, K; Yamaguchi, M; Yoshikawa, Y | 1 |
| Aguilar, F; Clark, TA; Edel, AL; Ganguly, PK; Heyliger, CE; Kopilas, M; Pierce, GN | 1 |
| Shah, DI; Singh, M | 1 |
| Baquer, NZ; Hussain, ME; Moorthy, K; Siddiqui, MR; Taha, A | 1 |
| Badhai, J; Baquer, NZ; Hussain, ME; Preet, A; Siddiqui, MR; Taha, A; Yadava, PK | 1 |
| Chen, M; Georgeson, KE; Harmon, CM; Loux, TJ; Yang, YK | 1 |
| Dabroś, W; Goc, A; Kordowiak, AM; Turyna, B | 1 |
| Choi, EW; Chung, JY; Hwang, CY; Kim, JM; Kim, MK; Lee, SY; Youn, HY | 1 |
| Halász, AS; Kocsis, E; Magyar, K; Pálfi, M; Soltész, Z; Szökö, E; Tábi, T; Tóth, M | 1 |
| Karmaker, S; Saha, TK; Sakurai, H; Yoshikawa, Y | 1 |
| Ding, W; Li, M; Wei, D | 1 |
| Baruah, B; Crans, DC; Ding, W; Li, M; Wei, D | 1 |
| Chen, GH; Lu, WL; Zhang, Q; Zhang, SQ; Zhong, XY | 1 |
| Sakurai, H | 1 |
| Ghareeb, DA; Hussen, HM | 1 |
| Yang, YK; Zhu, WY | 1 |
| Khandelwal, RL; Pugazhenthi, S | 2 |
| Chen, X; Diamond, J; Hei, YJ; McNeill, JH; Pelech, SL | 1 |
| Fujii, K; Sakurai, H; Tamura, H; Watanabe, H | 1 |
| McNeill, JH; Orvig, C; Yuen, VG | 2 |
| Shechter, Y; Shisheva, A | 1 |
| Ariano, D; Fedorak, RN; Madsen, KL | 1 |
| Bosia, S; Burdino, E; Grignolo, F; Ugazio, G | 1 |
| Aktan, F; Nebioglu, S | 1 |
| Brichard, SM; Girard, J; Henquin, JC; Ongemba, LN | 1 |
| Altan, VM; Ozçelikay, AT; Oztürk, Y; Pekiner, C; Yildizoğlu-Ari, N | 1 |
| Bosch, F; Sabater, J; Valera, A | 1 |
| Cam, MC; Faun, J; McNeill, JH | 1 |
| Adachi, K | 1 |
| Domingo, JL; Gomez, M; Keen, CL; Llobet, JM; Sanchez, DJ | 2 |
| Kempson, SA; Peavy, DE; Sanghvi, AN; Seifert, SA; Steenbergen, DK | 1 |
| Ayame, H; Inoue, H; Kaku, K; Kaneko, T; Matsutani, A; Tao, T | 1 |
| Becker, DJ; Carton, F; Henquin, JC; Ongemba, LN | 1 |
| Franklin, LA; Ganguli, S; Reuland, DJ; Tucker, M | 1 |
| Becker, DJ; Henquin, JC; Ongemba, LN | 1 |
| Bosch, F; Rodriguez-Gil, JE; Valera, A | 1 |
| Guaitani, A; Verrecchia, A | 1 |
| Fisher, MJ; McDowall, IL | 1 |
| Dryden, S; Kilpatrick, A; Malabu, UH; McCarthy, HD; Williams, G | 1 |
| Bauman, ME; Beaty, TM; Watkins, JB | 1 |
| Ikonomov, O; Shechter, Y; Shisheva, A | 1 |
| Corbella, J; Domingo, JL; Gomez, M; Llobet, JM; Sanchez, DJ | 1 |
| Endo, M | 1 |
| Altan, VM; Ozcelikay, AT; Oztürk, Y; Ozuari, A; Yidizoglu-Ari, N | 1 |
| Angel, JF; Khandelwal, RL; Pugazhenthi, S | 3 |
| Baquer, NZ; Kale, RK; Saxena, AK; Srivastava, P | 3 |
| Cam, MC; Cros, GH; Lazaro, R; McNeill, JH; Serrano, JJ | 1 |
| Lebovitz, HE | 1 |
| Khandelwal, RL; King, MJ; Pugazhenthi, S; Sharma, RK | 1 |
| Brichard, SM; Desbuquois, B; Girard, J | 1 |
| Karasu, C; Ozansoy, G; Ozçelikay, AT | 1 |
| Elangovan, V; Govindasamy, S; Maneemegalai, S; Nandhini, D; Sekar, N | 1 |
| Battell, M; McNeill, JH; Orvig, C; Thompson, KH | 1 |
| Barrera-Hernandez, G; Wanke, IE; Wong, NC | 1 |
| Berg, EA; Campbell, L; Kagey, M; Stapleton, SR; Wu, JY | 1 |
| Baquer, NZ; Upadhyaya, KC | 2 |
| Battell, ML; McNeill, JH; Yao, J | 1 |
| Grybos, R; Kordowiak, AM; Trzos, R | 1 |
| Croquet, F; Dahmane, A; Davy, J; Féger, J; Gil, S | 1 |
| Daar, J; Kopp, SJ; Laddaga, R; Paulson, DJ; Romano, FD | 1 |
| Wang, Y; Yu, B | 1 |
| Liang, Y; Yu, B; Yuan, M | 2 |
| Darakhshan, F; Hajduch, E; Hundal, HS | 1 |
| Gopalakrishnan, V; Hopfner, RL; McNeill, JR; Misurski, D; Wilson, TW | 1 |
| Dabroś, W; Dziga, D; Gryboś, R; Kordowiak, AM | 1 |
| Baquer, NZ; Gupta, BL | 1 |
| Amessou, M; Bortoli, S; Brichard, S; Collinet, M; Desbuquois, B; Girard, J; Liemans, V | 1 |
| Amin, SS; Brichard, SM; Buchet, JP; Crans, DC; Ongemba, LN; Reul, BA | 1 |
| DeFronzo, RA; Mandarino, L; Matsuda, M | 1 |
| Baquer, NZ; Raju, J; Upadhyaya, KC | 1 |
| Baquer, NZ; Gupta, D; Prakash, J; Raju, J | 1 |
| McNeill, JH; Orvig, C; Thompson, KH; Woo, LC; Yuen, VG | 1 |
| Baquer, NZ; Gupta, D; Raju, J; Rao, AR | 1 |
| Baquer, NZ; Gupta, D; Raju, J | 1 |
| Bhanot, S; Girn, J; McNeill, JH; Poucheret, P | 1 |
| Sakurai, H; Sano, H; Takino, T; Yasui, H | 1 |
| Fridkin, M; Gershonov, E; Goldwaser, I; Sekar, N; Shechter, Y; Sun, Q | 1 |
| Wang, YL; Yu, B | 1 |
| Gantz, I; Li, JY; Qu, SY; Yang, YK; Zeng, Q | 1 |
| Amin, SS; Anderson, OP; Brichard, SM; Crans, DC; Cryer, K; Dutta, SK; Eaton, SS; Miller, SM; Reul, BA; Zhang, B | 1 |
| Li, SH; McNeill, JH | 1 |
| Hamajima, Y; Matsushita, R; Sakurai, H; Takada, J; Takino, T; Yasui, H; Yoshitake, A | 1 |
| Crans, DC; Goldfine, AB; Khan, HR; Kostyniak, PJ; McNeill, JH; Willsky, GR; Yang, LQ | 1 |
| Brownsey, RW; Cam, MC; McNeill, JH; Rodrigues, B | 1 |
| Bhanot, S; McNeill, JH; Mohammad, A | 1 |
| Bhanot, S; Marzban, L; McNeill, JH | 1 |
| Kawabe, K; Kojima, Y; Sakurai, H; Sasagawa, T; Yoshikawa, Y | 1 |
| Dudek, B; Gryboś, R; Kordowiak, AM | 1 |
| Goyal, RK; Mehta, AA; Shinde, UA | 1 |
| Filipek, B; Grybos, R; Krosniak, M; Zachwieja, Z; Zygmunt, M | 1 |
| McNeill, JH; Mohammad, A; Sharma, V | 1 |
| Alexander, D; Gelato, MC; Marsh, K | 1 |
| Pandharpurkar, S; Shastri, NV | 1 |
| Bartrons, R; Carballo, E; Crepin, K; Hue, L; Miralpeix, M; Rousseau, GG | 1 |
| Fisher, MJ; Green, AK; McDowall, IL; Richardson, SC | 1 |
| Brichard, SM; Henquin, JC | 1 |
| Klein, DJ; Robertson, RP | 1 |
| Ali, M; Kunjara, S; McLean, P; Sochor, M | 1 |
| Baquer, NZ; Saxena, AK; Srivastava, P | 1 |
| Kimura, K; Ogura, M; Ogura, Y | 1 |
| Hoveyda, HR; McNeill, JH; Orvig, C; Yuen, VG | 1 |
| Braun, JE; Severson, DL | 1 |
| Bliss, T; Da Costa, C; Fernandes, LC; Foot, E; Leighton, B | 1 |
| Cros, G; McNeill, JH; Mongold, JJ; Ramanadham, S; Serrano, JJ | 1 |
| Gefel, D; Shechter, Y; Shisheva, A | 1 |
| Stephenson, GM | 1 |
| Begum, N; Draznin, B; Sussman, KE | 1 |
| Bennett, MI; Johnson, TM; Meisler, MH; Willsky, GR | 1 |
| Avidan, A; Davidson, MB; Venkatesan, N | 1 |
| Corbella, J; Domingo, JL; Gómez, M; Keen, CL; Llobet, JM | 1 |
| Ogura, M; Ogura, Y; Suzuki, T; Yamamoto, Y | 1 |
| Acara, M; Bennett, MI; Lohr, JW; McReynolds, J; Pochal, MA; Willsky, GR | 1 |
| Govindasamy, S; Sekar, N | 2 |
| Bosch, F; Fillat, C; Gómez-Foix, AM; Guinovart, JJ; Rodríguez-Gil, JE | 1 |
| Bailbé, D; Blondel, O; Portha, B; Serradas, P | 1 |
| Bartrons, R; Bollen, M; Miralpeix, M; Stalmans, W; Toth, B; Ventura, F | 1 |
| Andraghetti, G; Cordera, R; DeFronzo, RA; Rossetti, L | 1 |
| Blondel, O; Chevalier, B; Portha, B; Simon, J | 1 |
| Cros, GH; McNeill, JH; Mongold, JJ; Ramanadham, S; Serrano, JJ | 1 |
| Berger, J; Biswas, C; Brady, EJ; Pilch, PF; Saperstein, R; Strout, HV; Vicario, PP | 1 |
| Giaccari, A; Klein-Robbenhaar, E; Rossetti, L; Vogel, LR | 1 |
| Bailey, CJ; Brichard, SM; Henquin, JC | 1 |
| Khandelwal, RL; Mantha, SV; Pugazhenthi, S | 1 |
| Corbella, J; Domingo, JL; Llobet, JM | 1 |
| Bendayan, M; Gingras, D | 1 |
| Ariño, J; Bosch, F; Gómez-Foix, AM; Guinovart, JJ; Rodríguez-Gil, JE | 1 |
| Lauglin, MR; Rossetti, L | 1 |
| Backer, JM; Kahn, CR; Meyerovitch, J | 1 |
| Bailbe, D; Blondel, O; Portha, B | 1 |
| Buchan, AM; McNeill, JH; Pederson, RA; Ramanadham, S | 1 |
| Dobish, MP; Hajjar, JJ; Tomicic, TK | 1 |
| Bartrons, R; Carreras, J; Gil, J; Miralpeix, M | 1 |
| Schulz, LO | 1 |
| McNeill, JH; Tahiliani, AG | 1 |
| Farfel, Z; Meyerovitch, J; Sack, J; Shechter, Y | 1 |
| Brichard, SM; Henquin, JC; Okitolonda, W | 1 |
| Bassols, AM; Carreras, J; Carreras, M; Climent, F | 1 |
| Govindasamy, S; Kanthasamy, A; Sekar, N | 1 |
| Heyliger, CE; McNeill, JH; Tahiliani, AG | 1 |
10 review(s) available for vanadates and Alloxan Diabetes
| Article | Year |
|---|---|
Protein kinase B in the diabetic heart.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Activation; Glucose; Insulin; Myocardium; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Zucker; Vanadates | 2003 |
Pharmacokinetic study and trial for preparation of enteric-coated capsule containing insulinomimetic vanadyl compounds: implications for clinical use.
Topics: Administration, Oral; Animals; Capsules; Diabetes Mellitus, Experimental; Electron Spin Resonance Spectroscopy; Gelatin; Hypoglycemic Agents; Molecular Structure; Organometallic Compounds; Picolinic Acids; Rats; Rats, Wistar; Vanadates; Vanadium Compounds | 2004 |
[Treatment of diabetes in experimental animals by metallocomplexes].
Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Drug Design; Glucose Transporter Type 4; Humans; Hypoglycemic Agents; Metabolic Syndrome; Vanadates; Zinc Compounds | 2008 |
Vanadium salts and the future treatment of diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Vanadates; Vanadium | 1993 |
Insulin-mimetic and insulin-sensitizing drugs.
Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Humans; Hypoglycemic Agents; Insulin; Thiazoles; Vanadates | 1993 |
Vanadium compounds as insulin mimics.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Rats; Rats, Inbred BB; Vanadates | 1995 |
[Role of vanadium in the treatment of diabetes mellitus. Experimental data and clinical applications].
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Rats; Vanadates; Vanadium | 1992 |
Treatment of diabetes mellitus.
Topics: Animals; Antihypertensive Agents; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Insulin; Islets of Langerhans Transplantation; Pancreas Transplantation; Rats; Rats, Inbred SHR; Risk Factors; Vanadates | 1992 |
Effects of vanadyl derivatives on animal models of diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diarrhea; Energy Metabolism; Humans; Insulin; Insulin Resistance; Lipolysis; Mice; Mice, Mutant Strains; Rats; Rats, Brattleboro; Vanadates | 1992 |
Diabetes-induced abnormalities in the myocardium.
Topics: Adenosine Triphosphatases; Animals; Blood Glucose; Calcium; Carbohydrate Metabolism; Cardiomyopathies; Carnitine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diabetic Neuropathies; Epoxy Compounds; Fatty Acids; Heart; Heart Diseases; Hemodynamics; Humans; Insulin; Isoenzymes; Microscopy, Electron; Myocardial Contraction; Myocardium; Myosins; Propionates; Sarcolemma; Sarcoplasmic Reticulum; Triiodothyronine; Vanadates; Vanadium | 1986 |
1 trial(s) available for vanadates and Alloxan Diabetes
| Article | Year |
|---|---|
Effect of vanadium(IV) compounds in the treatment of diabetes: in vivo and in vitro studies with vanadyl sulfate and bis(maltolato)oxovandium(IV).
Topics: Animals; Apoproteins; Biological Availability; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Electron Spin Resonance Spectroscopy; Fasting; Humans; Hypoglycemic Agents; Immunoglobulin G; Male; Pyrones; Rats; Rats, Wistar; Serum Albumin; Streptozocin; Transferrin; Treatment Outcome; Vanadates; Vanadium; Vanadium Compounds | 2001 |
205 other study(ies) available for vanadates and Alloxan Diabetes
| Article | Year |
|---|---|
Heteroleptic oxidovanadium(IV)-malate complex improves glucose uptake in HepG2 and enhances insulin action in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Humans; Hypoglycemic Agents; Insulin; Malates; Male; Rats; Rats, Wistar; Streptozocin; Vanadates; Vanadium | 2022 |
The role of apoptosis and autophagy in the insulin-enhancing activity of oxovanadium(IV) bipyridine complex in streptozotocin-induced diabetic mice.
Topics: 2,2'-Dipyridyl; Administration, Oral; Animals; Antioxidants; Apoptosis; Autophagy; Coordination Complexes; Diabetes Mellitus, Experimental; Injections, Intraperitoneal; Insulin; Male; Mice; Streptozocin; Vanadates | 2020 |
Insulin-Sensitizing Activity of Sub-Nanoscaled Polyalkoxyvanadate Clusters.
Topics: Animals; Blood Glucose; Decanoic Acids; Diabetes Mellitus, Experimental; Insulin; Male; Mice; Myristic Acid; Vanadates | 2020 |
Attenuation of macrophage accumulation and polarisation in obese diabetic mice by a small molecule significantly improved insulin sensitivity.
Topics: Animals; Cell Polarity; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Inflammation; Insulin Resistance; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Obese; Obesity; RAW 264.7 Cells; Vanadates | 2018 |
Synthesis of a vanadyl (IV) folate complex for the treatment of diabetes: spectroscopic, structural, and biological characterization.
Topics: Animals; Diabetes Mellitus, Experimental; Electron Spin Resonance Spectroscopy; Folic Acid; Hypoglycemic Agents; Male; Molecular Structure; Organometallic Compounds; Particle Size; Rats; Spectrophotometry, Infrared; Streptozocin; Surface Properties; Thermodynamics; Vanadates | 2019 |
Effect of lower doses of vanadate in combination with Azadirachta indica leaf extract on hepatic and renal antioxidant enzymes in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Azadirachta; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hypoglycemic Agents; Kidney; Liver; Male; Oxidoreductases; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Vanadates | 2013 |
Changes in iron metabolism and oxidative status in STZ-induced diabetic rats treated with bis(maltolato) oxovanadium (IV) as an antidiabetic agent.
Topics: Animals; Catalase; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Iron; Kidney; Liver; Male; Muscle, Skeletal; Myocardium; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Pyrones; Rats; Spleen; Superoxide Dismutase; Vanadates | 2014 |
Morphological analysis of the pancreas and liver in diabetic KK-A(y) mice treated with zinc and oxovanadium complexes.
Topics: Adiposity; Animals; Behavior, Animal; Biomarkers; Blood Glucose; Body Weight; Coordination Complexes; Diabetes Mellitus, Experimental; Liver; Male; Mice, Inbred C57BL; Pancreas; Testis; Vanadates; Zinc | 2014 |
Synthesis, spectroscopic, structural and thermal characterizations of vanadyl(IV) adenine complex prospective as antidiabetic drug agent.
Topics: Animals; Blood Glucose; Coordination Complexes; Creatinine; Diabetes Mellitus, Experimental; Electric Conductivity; Electron Spin Resonance Spectroscopy; Electrons; Hypoglycemic Agents; Insulin; Kinetics; Ligands; Lipids; Liver; Magnetic Phenomena; Male; Mice; Microscopy, Electron, Scanning; Pancreas; Spectrometry, Fluorescence; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Temperature; Thermogravimetry; Uric Acid; Vanadates; X-Ray Diffraction | 2015 |
Sodium Orthovanadate and Trigonella Foenum Graecum Prevents Neuronal Parameters Decline and Impaired Glucose Homeostasis in Alloxan Diabetic Rats.
Topics: Animals; Blood Glucose; Brain Chemistry; Calcium; Diabetes Mellitus, Experimental; Female; Insulin; Lipid Peroxidation; Lipofuscin; Monoamine Oxidase; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Seeds; Trigonella; Vanadates | 2015 |
Green Synthesis of Oxovanadium(IV)/chitosan Nanocomposites and Its Ameliorative Effect on Hyperglycemia, Insulin Resistance, and Oxidative Stress.
Topics: Animals; Chitosan; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Stability; Glucose Tolerance Test; Green Chemistry Technology; Hyperglycemia; Insulin Resistance; Liver; Male; Mice, Inbred C57BL; Nanocomposites; Oxidative Stress; Vanadates | 2016 |
Bis(maltolato)oxovanadium(IV) (BMOV) Attenuates Apoptosis in High Glucose-Treated Cardiac Cells and Diabetic Rat Hearts by Regulating the Unfolded Protein Responses (UPRs).
Topics: Animals; Apoptosis; Cell Line; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Glucose; Male; Myocardium; Pyrones; Rats; Rats, Sprague-Dawley; Unfolded Protein Response; Vanadates | 2016 |
Metforminium Decavanadate as a Potential Metallopharmaceutical Drug for the Treatment of Diabetes Mellitus.
Topics: Animals; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Glycated Hemoglobin; Glycogen; Hyperglycemia; Insulin; Male; Metformin; Rats, Wistar; Triglycerides; Vanadates | 2016 |
Effect of vanadium on calcium homeostasis, osteopontin mRNA expression, and bone microarchitecture in diabetic rats.
Topics: Animals; Bone and Bones; Calcium; Diabetes Mellitus, Experimental; Homeostasis; Male; Osteopontin; Pyrones; Rats; Rats, Wistar; RNA, Messenger; Vanadates; X-Ray Microtomography | 2017 |
Effective control of blood glucose status and toxicity in streptozotocin-induced diabetic rats by orally administration of vanadate in an herbal decoction.
Topics: Animals; Biomarkers; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Drinking; Eating; Glucose Tolerance Test; Hypoglycemic Agents; Lipid Metabolism; Male; Organ Size; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Salvia miltiorrhiza; Vanadates | 2008 |
Synthesis, characterization and antidiabetic properties of N(1)-2,4-dihydroxybenzylidene-N(4)-2-hydroxybenzylidene-S-methyl-thiosemicarbazidato-oxovanadium(IV).
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Molecular Mimicry; Organometallic Compounds; Pancreas; Protective Agents; Rats; Regeneration; Spectrum Analysis; Treatment Outcome; Vanadates | 2009 |
Anti-diabetic effects of vanadium(III, IV, V)-chlorodipicolinate complexes in streptozotocin-induced diabetic rats.
Topics: Administration, Oral; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Blood Glucose; Blood Urea Nitrogen; Chlorine; Cholesterol; Creatinine; Diabetes Mellitus, Experimental; Disease Models, Animal; Hypoglycemic Agents; Insulin; Kidney Function Tests; Oxidation-Reduction; Picolinic Acids; Rats; Rats, Wistar; Streptozocin; Triglycerides; Vanadates; Vanadium | 2009 |
Insulin-enhancing activity of a dinuclear vanadium complex: 5-chloro-salicylaldhyde ethylenediamine oxovanadium(V) and its permeability and cytotoxicity.
Topics: Animals; Blood Glucose; Caco-2 Cells; Cell Survival; Diabetes Mellitus, Experimental; Humans; Hypoglycemic Agents; Insulin; Male; Molecular Structure; Rats; Rats, Sprague-Dawley; Vanadates; Vanadium | 2010 |
Restoration of cardiomyocyte function in streptozotocin-induced diabetic rats after treatment with vanadate in a tea decoction.
Topics: Animals; Blood Glucose; Calcium; Diabetes Mellitus, Experimental; Myocytes, Cardiac; Phosphatidic Acids; Rats; Rats, Sprague-Dawley; Tea; Vanadates | 2010 |
Comparison of hypoglycemic activity of fermented mushroom of Inonotus obliquus rich in vanadium and wild-growing I. obliquus.
Topics: Agaricales; Animals; Biological Availability; Blood Glucose; Body Weight; Culture Media; Diabetes Mellitus, Experimental; Endpoint Determination; Female; Fermentation; Heart; Hypoglycemic Agents; Kidney; Liver; Mice; Organ Size; Vanadates; Vanadium | 2011 |
A new salicylic acid-derivatized kojic acid vanadyl complex: synthesis, characterization and anti-diabetic therapeutic potential.
Topics: Animals; Blood Glucose; Coordination Complexes; Diabetes Mellitus; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Liver; Male; Pyrones; Rats; Rats, Sprague-Dawley; Salicylic Acid; Vanadates | 2011 |
Protection by vanadium, a contemporary treatment approach to both diabetes and focal cerebral ischemia in rats.
Topics: Animals; Blood Glucose; Body Weight; Brain; Brain Ischemia; Catalase; Diabetes Mellitus, Experimental; Female; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Infarction, Middle Cerebral Artery; Insulin; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Neuroprotective Agents; Oxidative Stress; Psychomotor Performance; Rats; Rats, Wistar; Survival Rate; Vanadates | 2012 |
ALAS1 gene expression is down-regulated by Akt-mediated phosphorylation and nuclear exclusion of FOXO1 by vanadate in diabetic mice.
Topics: 5-Aminolevulinate Synthetase; Animals; Base Sequence; Cell Nucleus; Diabetes Mellitus, Experimental; Down-Regulation; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Insulin; Liver; Male; Mice; Multiprotein Complexes; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; Porphyria, Acute Intermittent; Proto-Oncogene Proteins c-akt; RNA, Messenger; Trans-Activators; Transcription Factors; Vanadates | 2012 |
Effect of bis(maltolato)oxovanadium (IV) (BMOV) on selenium nutritional status in diabetic streptozotocin rats.
Topics: Animals; Diabetes Mellitus, Experimental; Male; Nutritional Status; Pyrones; Rats; Rats, Wistar; Selenium; Vanadates | 2012 |
A tea/vanadate decoction delivered orally over 14 months to diabetic rats induces long-term glycemic stability without organ toxicity.
Topics: Amylases; Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Drinking; Eating; Glycated Hemoglobin; Hypoglycemic Agents; Insulin; Islets of Langerhans; Kidney Function Tests; Liver Function Tests; Male; Rats; Rats, Sprague-Dawley; Tea; Triglycerides; Vanadates | 2012 |
Beneficial effects of Trigonella foenum graecum and sodium orthovanadate on metabolic parameters in experimental diabetes.
Topics: Alloxan; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Female; L-Lactate Dehydrogenase; Oxidative Stress; Plant Extracts; Protein Kinase C; Pyruvate Kinase; Rats; Rats, Wistar; Seeds; Trigonella; Vanadates | 2012 |
Effect of diabetes on the ion pumps of the bladder.
Topics: Animals; Body Weight; Diabetes Mellitus, Experimental; Enzyme Inhibitors; In Vitro Techniques; Indoles; Ion Pumps; Male; Muscle Contraction; Muscle, Smooth; Ouabain; Rats; Rats, Sprague-Dawley; Time Factors; Urinary Bladder; Urinary Bladder Diseases; Vanadates | 2013 |
Decreasing the diabetic complication by vanadyl(VO)2+/vitamin B 6 complex in alloxan-induced diabetic mice.
Topics: Alloxan; Animals; Creatinine; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Glucosephosphate Dehydrogenase; L-Lactate Dehydrogenase; Male; Mice; Uric Acid; Vanadates; Vitamin B 6 | 2013 |
Structure-dependent metallokinetics of antidiabetic vanadyl-picolinate complexes in rats: studies on solution structure, insulinomimetic activity, and metallokinetics.
Topics: Adipocytes; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Electron Spin Resonance Spectroscopy; Epinephrine; Fatty Acids, Nonesterified; Hypoglycemic Agents; Insulin; Male; Molecular Structure; Picolinic Acids; Rats; Rats, Wistar; Statistics as Topic; Vanadates | 2002 |
Alterations in antioxidant enzymes and oxidative damage in experimental diabetic rat tissues: effect of vanadate and fenugreek (Trigonellafoenum graecum).
Topics: Alloxan; Animals; Antioxidants; Body Weight; Brain; Catalase; Diabetes Mellitus, Experimental; Female; Glutathione Peroxidase; Insulin; Kidney; Lipid Peroxidation; Liver; Organ Size; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Superoxide Dismutase; Time Factors; Trigonella; Vanadates | 2002 |
Mechanisms by which bis(maltolato)oxovanadium(IV) normalizes phosphoenolpyruvate carboxykinase and glucose-6-phosphatase expression in streptozotocin-diabetic rats in vivo.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Gene Expression; Glucose-6-Phosphatase; Hypoglycemic Agents; Insulin; Kidney; Liver; Male; Phlorhizin; Phosphoenolpyruvate Carboxykinase (GTP); Pyrones; Rats; Rats, Wistar; RNA, Messenger; Vanadates | 2002 |
The influence of BMOV [bis(maltolato)oxovanadium(IV)] on biochemical and morphological alterations characteristic for streptozotocin-diabetic rat liver Golgi complexes.
Topics: Animals; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Female; Galactosyltransferases; Golgi Apparatus; Liver; Microscopy, Electron; Pyrones; Rats; Rats, Wistar; Vanadates | 2002 |
Oral administration of orthovanadate and Trigonella foenum graecum seed power restore the activities of mitochondrial enzymes in tissues of alloxan-induced diabetic rats.
Topics: Administration, Oral; Alloxan; Animals; Arginase; Brain; Diabetes Mellitus, Experimental; Enzyme-Linked Immunosorbent Assay; Enzymes; Female; Kidney; Liver; Mitochondria; Oxidoreductases; Phytotherapy; Rats; Rats, Wistar; Seeds; Transaminases; Trigonella; Vanadates | 2003 |
[Hypoglycemic effects of sodium metavanadate in diabetic mice and its effect on glucose phosphorylation].
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Glucokinase; Hexokinase; Hypoglycemic Agents; Insulin; Liver; Mice; Mice, Inbred ICR; Muscle, Skeletal; Phosphorylation; Random Allocation; Vanadates | 2003 |
Reactivity of tracheal smooth muscles in albino rats with experimental diabetes mellitus treated with a new complex compound of oxovanadium (IV) and isonicotinic acid hydrazide.
Topics: Alloxan; Animals; Carbachol; Cholinergic Agonists; Diabetes Mellitus, Experimental; Drug Combinations; Female; Isoniazid; Male; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Rats; Trachea; Vanadates | 2003 |
Vanadate improves cardiac function and myocardial energy metabolism in diabetic rat hearts.
Topics: Animals; Diabetes Mellitus, Experimental; Energy Metabolism; Heart; Male; Myocardium; Rats; Rats, Wistar; Vanadates | 2003 |
Insulin mimetic effects of macrocyclic binuclear oxovanadium complexes on streptozotocin-induced experimental diabetes in rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Insulin; Liver; Male; Rats; Rats, Wistar; Structure-Activity Relationship; Urea; Vanadates | 2003 |
Chronic glucose-lowering effects of rosiglitazone and bis(ethylmaltolato)oxovanadium(IV) in ZDF rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Drug Administration Schedule; Drug Therapy, Combination; Insulin; Intubation, Gastrointestinal; Male; Pyrones; Rats; Rats, Zucker; Rosiglitazone; Thiazolidinediones; Vanadates | 2003 |
A new candidate for insulinomimetic vanadium complex: synergism of oxovanadium(IV)porphyrin and sodium ascorbate.
Topics: Animals; Ascorbic Acid; Biomimetic Materials; Blood Glucose; Diabetes Mellitus, Experimental; Drug Synergism; Insulin; Rats; Vanadates; Vanadium | 2004 |
Stimulation of glucose transport by semicarbazide-sensitive amine oxidase activity in adipocytes from diabetic rats.
Topics: Adipocytes; Amine Oxidase (Copper-Containing); Animals; Benzylamines; Biological Transport; Deoxyglucose; Diabetes Mellitus, Experimental; Insulin; Male; Rats; Rats, Mutant Strains; Rats, Wistar; Vanadates | 2003 |
Effect of prolonged treatment with tyramine on glucose tolerance in streptozotocin-induced diabetic rats.
Topics: Adipocytes; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucose; Glucose Tolerance Test; Infusion Pumps; Injections, Intraperitoneal; Insulin; Male; Rats; Rats, Wistar; Tyramine; Vanadates | 2003 |
Lower doses of vanadate in combination with trigonella restore altered carbohydrate metabolism and antioxidant status in alloxan-diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hypoglycemic Agents; Kidney; Liver; Phytotherapy; Plant Preparations; Rats; Rats, Wistar; Trigonella; Vanadates | 2004 |
Streptozotocin-induced alterations in rat liver Golgi complexes are ameliorated by BMOV [Bis(maltolato)oxovanadium(IV)] activity.
Topics: Animals; Diabetes Mellitus, Experimental; Female; Galactosyltransferases; Golgi Apparatus; Hypoglycemic Agents; Liver; Microscopy, Electron; Osmolar Concentration; Phospholipids; Pyrones; Rats; Rats, Wistar; Sodium Chloride; Vanadates; Vanadium | 2004 |
Comparison of anti-hyperglycemic effect amongst vanadium, molybdenum and other metal maltol complexes.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Male; Molybdenum; Organometallic Compounds; Pyrones; Rats; Rats, Wistar; Vanadates; Vanadium | 2004 |
[Hypoglycemic effects of bis(maltolato)oxovanadium administered by different routes upon diabetic rats].
Topics: Administration, Oral; Alloxan; Animals; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Insulin; Male; Pyrones; Rats; Rats, Wistar; Vanadates | 2004 |
Caraway and caper: potential anti-hyperglycaemic plants in diabetic rats.
Topics: Administration, Oral; Animals; Blood Glucose; Capparis; Carum; Diabetes Mellitus, Experimental; Fruit; Hypoglycemic Agents; Insulin; Male; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Streptozocin; Vanadates | 2004 |
Phlorizin-like effect of Fraxinus excelsior in normal and diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Fraxinus; Hypoglycemic Agents; Insulin; Phlorhizin; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Seeds; Streptozocin; Vanadates | 2004 |
Protective effects of sodium orthovanadate in diabetic reticulocytes and ageing red blood cells of Wistar rats.
Topics: Animals; Blood Glucose; Cellular Senescence; Diabetes Mellitus, Experimental; Erythrocytes; Female; Hypoglycemic Agents; Insulin; Rats; Rats, Wistar; Reticulocytes; Vanadates | 2004 |
Effects of sodium-orthovanadate and Trigonella foenum-graecum seeds on hepatic and renal lipogenic enzymes and lipid profile during alloxan diabetes.
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Kidney; Lipid Metabolism; Liver; Phytotherapy; Plant Preparations; Rats; Rats, Wistar; Seeds; Trigonella; Vanadates | 2004 |
Codelivery of a tea extract prevents morbidity and mortality associated with oral vanadate therapy in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Cataract; Cholesterol; Diabetes Mellitus, Experimental; Diarrhea; Drinking; Eating; Hypoglycemic Agents; Liver Function Tests; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Tea; Triglycerides; Vanadates | 2004 |
Protective effect of macrocyclic binuclear oxovanadium complex on oxidative stress in pancreas of streptozotocin induced diabetic rats.
Topics: Administration, Oral; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Lipid Peroxidation; Male; Oxidative Stress; Pancreas; Rats; Rats, Wistar; Streptozocin; Vanadates | 2004 |
Effects of vanadate on the activities of mice glucokinase and hexokinase.
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Enzyme Activation; Female; Glucokinase; Hexokinase; Insulin; Liver; Mice; Mice, Inbred ICR; Muscle, Skeletal; Treatment Outcome; Vanadates | 2004 |
Complementary inhibition of synoviocyte, smooth muscle cell or mouse lymphoma cell proliferation by a vanadyl curcumin complex compared to curcumin alone.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Blood Glucose; Cell Division; Cell Line; Cell Line, Tumor; Cell Survival; Curcumin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Synergism; Growth Inhibitors; Hypoglycemic Agents; Leukemia L1210; Male; Mice; Molecular Structure; Muscle, Smooth, Vascular; Rabbits; Rats; Rats, Wistar; Synovial Membrane; Vanadates | 2004 |
Combined treatment of sodium orthovanadate and Momordica charantia fruit extract prevents alterations in lipid profile and lipogenic enzymes in alloxan diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Enzymes; Kidney; Lipid Metabolism; Liver; Male; Momordica charantia; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Vanadates | 2005 |
Coordination chemistry and insulin-enhancing behavior of vanadium complexes with maltol C6H6O3 structural isomers.
Topics: Animals; Blood Glucose; Crystallography, X-Ray; Diabetes Mellitus, Experimental; Hydrogen-Ion Concentration; Hypoglycemic Agents; Insulin; Isomerism; Ligands; Pyrones; Rats; Time Factors; Vanadates; Vanadium Compounds | 2005 |
Sodium orthovanadate exerts influence on liver Golgi complexes from control and streptozotocin-diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Female; Golgi Apparatus; Liver; Rats; Vanadates | 2005 |
The effects of peroxovanadate and peroxovanadyl on glucose metabolism in vivo and identification of signal transduction proteins involved in the mechanism of action in isolated soleus muscle.
Topics: Animals; Diabetes Mellitus, Experimental; Glucose; Glycogen; Hyperglycemia; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Skeletal; Phosphorylation; Rats; Rats, Wistar; Signal Transduction; Vanadates; Vanadium Compounds | 2005 |
Synthesis and characterization of dual function vanadyl, gallium and indium curcumin complexes for medicinal applications.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Crystallography, X-Ray; Curcumin; Diabetes Mellitus, Experimental; Gallium; Indium; Leukemia L1210; Male; Mice; Rats; Rats, Wistar; Vanadates | 2005 |
Restoration of ultrastructural and biochemical changes in alloxan-induced diabetic rat sciatic nerve on treatment with Na3VO4 and Trigonella--a promising antidiabetic agent.
Topics: Aldehyde Reductase; Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Fructose; Glucosephosphate Dehydrogenase; Glutathione; Hexokinase; Hypoglycemic Agents; L-Iditol 2-Dehydrogenase; Microscopy, Electron, Transmission; Phytotherapy; Plant Preparations; Rats; Rats, Wistar; Sciatic Nerve; Sorbitol; Trigonella; Vanadates | 2005 |
Amelioration of altered antioxidant status and membrane linked functions by vanadium and Trigonella in alloxan diabetic rat brains.
Topics: Animals; Brain; Cell Membrane; Diabetes Mellitus, Experimental; Female; Lipid Peroxidation; Oxidative Stress; Rats; Rats, Wistar; Seeds; Sodium-Potassium-Exchanging ATPase; Trace Elements; Trigonella; Vanadates; Vanadium | 2005 |
Glucose handling in streptozotocin-induced diabetic rats is improved by tyramine but not by the amine oxidase inhibitor semicarbazide.
Topics: Adipocytes; Adipose Tissue; Amine Oxidase (Copper-Containing); Animals; Benzylamines; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucose; Kidney; Lipolysis; Liver; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Myocardium; Oxidation-Reduction; Pargyline; Rats; Rats, Wistar; Semicarbazides; Tyramine; Vanadates | 2005 |
The effects of vanadium treatment on bone in diabetic and non-diabetic rats.
Topics: Absorptiometry, Photon; Administration, Oral; Animals; Biomechanical Phenomena; Blood Glucose; Body Weight; Bone and Bones; Bone Density; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Insulin; Radioimmunoassay; Random Allocation; Rats; Rats, Wistar; Triglycerides; Vanadates; X-Ray Diffraction | 2006 |
Modulation of glucose transporter (GLUT4) by vanadate and Trigonella in alloxan-diabetic rats.
Topics: Alloxan; Animals; Blood Glucose; Cell Fractionation; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin; Muscle, Skeletal; Plant Extracts; Rats; Rats, Wistar; Trigonella; Vanadates | 2006 |
Syntheses of vanadyl and zinc(II) complexes of 1-hydroxy-4,5,6-substituted 2(1H)-pyrimidinones and their insulin-mimetic activities.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Evaluation, Preclinical; Electron Spin Resonance Spectroscopy; Hypoglycemic Agents; Inhibitory Concentration 50; Insulin; Ligands; Male; Molecular Mimicry; Molecular Structure; Organometallic Compounds; Pyrimidinones; Rats; Rats, Wistar; Vanadates; Zinc | 2006 |
Short-term bioaccumulation of vanadium when ingested with a tea decoction in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Male; Rats; Rats, Sprague-Dawley; Spectrophotometry, Atomic; Tea; Tissue Distribution; Vanadates | 2006 |
Inhibition of protein tyrosin phosphatase improves vascular endothelial dysfunction.
Topics: Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Hyperhomocysteinemia; Male; Methionine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Potassium Channels; Protein Tyrosine Phosphatases; Pyrones; Rats; Rats, Sprague-Dawley; Streptozocin; Thiobarbituric Acid Reactive Substances; Vanadates; Vasodilation | 2006 |
Low doses of vanadate and Trigonella synergistically regulate Na+/K + -ATPase activity and GLUT4 translocation in alloxan-diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Female; Glucose Transporter Type 4; Hypoglycemic Agents; Lipid Peroxidation; Membrane Fluidity; Membrane Lipids; Myocardium; Phytotherapy; Plant Preparations; Protein Transport; Rats; Rats, Wistar; Seeds; Sodium-Potassium-Exchanging ATPase; Trigonella; Vanadates | 2006 |
Long-term effect of Trigonella foenum graecum and its combination with sodium orthovanadate in preventing histopathological and biochemical abnormalities in diabetic rat ocular tissues.
Topics: Aldehyde Reductase; Animals; Antioxidants; Diabetes Mellitus, Experimental; Female; Glucose; Glucosephosphate Dehydrogenase; Glutathione Peroxidase; Glutathione Reductase; Herb-Drug Interactions; Hexokinase; Insulin; L-Iditol 2-Dehydrogenase; Lens, Crystalline; Lipid Peroxidation; Plant Extracts; Rats; Rats, Wistar; Retina; Sorbitol; Time Factors; Trigonella; Vanadates | 2006 |
The role of hyperglycemia in FAT/CD36 expression and function.
Topics: Adipose Tissue; Animals; Blood Glucose; Blotting, Northern; Blotting, Western; Body Weight; CD36 Antigens; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Gene Expression Regulation; Hyperglycemia; Insulin; Intestine, Small; Male; PPAR gamma; Radioimmunoassay; Rats; Rats, Sprague-Dawley; RNA, Messenger; Streptozocin; Vanadates | 2006 |
Sodium metavanadate affected control and streptozotocin-diabetic rat liver golgi complexes.
Topics: Administration, Oral; Animals; Blood Glucose; Body Weight; Cytoplasm; Diabetes Mellitus, Experimental; Drinking; Drug Antagonism; Eating; Female; Galactosyltransferases; Golgi Apparatus; Hepatocytes; Hypoglycemic Agents; Liver; Microscopy, Electron, Transmission; Organ Size; Rats; Rats, Wistar; Vanadates | 2006 |
Hypoglycemic effects of vanadium on alloxan monohydrate induced diabetic dogs.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Blood Glucose; Blood Urea Nitrogen; Chlorides; Cholesterol; Creatinine; Diabetes Mellitus, Experimental; Dog Diseases; Dogs; Female; Fructosamine; Hypoglycemic Agents; Male; Pancreas; Potassium; Random Allocation; Sodium; Triglycerides; Vanadates | 2006 |
Studies on the insulinomimetic effects of benzylamine, exogenous substrate of semicarbazide-sensitive amine oxidase enzyme in streptozotocin induced diabetic rats.
Topics: Amine Oxidase (Copper-Containing); Animals; Benzylamines; Blood Glucose; Diabetes Mellitus, Experimental; Down-Regulation; Drug Synergism; Drug Therapy, Combination; Glycated Hemoglobin; Glycation End Products, Advanced; Hypoglycemic Agents; Insulin; Male; Nitric Oxide; Rats; Rats, Wistar; Vanadates | 2007 |
Amelioration of hyperglycemia and metabolic syndromes in type 2 diabetic KKA(y) mice by poly(gamma-glutamic acid)oxovanadium(IV) complex.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Hyperglycemia; Insulin; Leptin; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Obesity; Polyglutamic Acid; Vanadates | 2007 |
Effect of vanadate on gene expression of the insulin signaling pathway in skeletal muscle of streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Gene Expression; Gene Expression Profiling; Glucose Tolerance Test; Glycogen; Hypoglycemic Agents; Insulin; Muscle, Skeletal; Oligonucleotide Array Sequence Analysis; Rats; Rats, Wistar; Signal Transduction; Streptozocin; Vanadates | 2007 |
Anti-diabetic effects of cesium aqua (N,N'-ethylene(salicylideneiminato)-5-sulfonato) oxovanadium (IV) dihydrate in streptozotocin-induced diabetic rats.
Topics: Animals; Aspartate Aminotransferases; Blood Glucose; Blood Urea Nitrogen; Diabetes Mellitus, Experimental; Glycogen; Hypoglycemic Agents; Liver; Male; Molecular Structure; Muscles; Organometallic Compounds; Rats; Rats, Wistar; Streptozocin; Vanadates | 2008 |
The anti-diabetic effects and pharmacokinetic profiles of bis(maltolato)oxovanadium in non-diabetic and diabetic rats.
Topics: Administration, Oral; Alloxan; Animals; Area Under Curve; Biological Availability; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Femur; Half-Life; Hypoglycemic Agents; Injections, Intravenous; Injections, Subcutaneous; Kidney; Male; Pyrones; Rats; Rats, Sprague-Dawley; Time Factors; Vanadates | 2008 |
Vanadium improves brain acetylcholinesterase activity on early stage alloxan-diabetic rats.
Topics: Acetylcholinesterase; Alloxan; Animals; Blood Glucose; Brain; Diabetes Mellitus, Experimental; Glutathione Transferase; Hypoglycemic Agents; Isoenzymes; Lipid Peroxidation; Rats; Thiobarbituric Acid Reactive Substances; Vanadates | 2008 |
[Effect of serum glucose on the function of pancreatic exocrine in diabetic rats].
Topics: Amylases; Animals; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Experimental; Male; Malondialdehyde; Pancreas; Rats; Rats, Wistar; Sincalide; Vanadates | 1994 |
Does the insulin-mimetic action of vanadate involve insulin receptor kinase?
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Insulin; Kinetics; Liver; Male; Phosphorylation; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Reference Values; Tyrosine; Vanadates; Weight Gain | 1993 |
Skeletal muscle mitogen-activated protein kinases and ribosomal S6 kinases. Suppression in chronic diabetic rats and reversal by vanadium.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chromatography, Ion Exchange; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Insulin; Insulin Resistance; Kinetics; Muscle, Skeletal; Protein Serine-Threonine Kinases; Pyrones; Rats; Rats, Wistar; Reference Values; Ribosomal Protein S6 Kinases; Ribosomes; Time Factors; Vanadates; Vanadium; Vanadium Compounds | 1995 |
Orally active and long-term acting insulin-mimetic vanadyl complex:bis(picolinato)oxovanadium (IV).
Topics: Adipocytes; Administration, Oral; Animals; Blood Glucose; Body Weight; Cells, Cultured; Diabetes Mellitus, Experimental; Epinephrine; Fatty Acids, Nonesterified; Hypoglycemic Agents; Insulin; Molecular Structure; Picolinic Acids; Rats; Rats, Wistar; Time Factors; Vanadates | 1995 |
Comparison of the glucose-lowering properties of vanadyl sulfate and bis(maltolato)oxovanadium(IV) following acute and chronic administration.
Topics: Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hypoglycemic Agents; Injections, Intraperitoneal; Injections, Intravenous; Male; Pyrones; Rats; Rats, Wistar; Time Factors; Vanadates; Vanadium Compounds | 1995 |
Vanadate treatment rapidly improves glucose transport and activates 6-phosphofructo-1-kinase in diabetic rat intestine.
Topics: Analysis of Variance; Animals; Biological Transport; Blood Glucose; Cycloheximide; Diabetes Mellitus, Experimental; Enzyme Activation; Glucose; Hyperglycemia; Ileum; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Microvilli; Phosphofructokinase-1; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Vanadates | 1995 |
Amelioration of diabetes and cataract by Na3VO4 plus U-83836E in streptozotocin treated rats.
Topics: Acetylglucosaminidase; Animals; Cataract; Chromans; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Free Radical Scavengers; Fructosamine; Glycated Hemoglobin; Hexosamines; Lens, Crystalline; Male; Peroxides; Piperazines; Rats; Rats, Wistar; Streptozocin; Vanadates | 1994 |
Effect of vanadium compounds on calmodulin activity in experimental diabetes in rats.
Topics: Adipose Tissue; Animals; Blood Glucose; Calmodulin; Diabetes Mellitus, Experimental; Insulin; Liver; Male; Rats; Vanadates; Vanadium | 1994 |
Tissue-specific correction of lipogenic enzyme gene expression in diabetic rats given vanadate.
Topics: Acetyl-CoA Carboxylase; Adipose Tissue; Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Fatty Acid Synthases; Gene Expression Regulation, Enzymologic; Lipid Metabolism; Liver; Male; Rats; Rats, Wistar; RNA, Messenger; Thyroid Hormones; Vanadates | 1994 |
Vanadate treatment reverses gastrointestinal complications in the streptozotocin-diabetic rats.
Topics: Animals; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Duodenum; Gastrointestinal Diseases; In Vitro Techniques; Insulin; Male; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Streptozocin; Vanadates | 1994 |
Insulin inhibits liver expression of the CCAAT/enhancer-binding protein beta.
Topics: Animals; Blood Glucose; CCAAT-Enhancer-Binding Proteins; Diabetes Mellitus, Experimental; DNA-Binding Proteins; Gene Expression; Humans; Insulin; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nuclear Proteins; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Reference Values; RNA, Messenger; Transcription Factors; Vanadates | 1995 |
Concentration-dependent glucose-lowering effects of oral vanadyl are maintained following treatment withdrawal in streptozotocin-diabetic rats.
Topics: Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Insulin; Male; Osmolar Concentration; Rats; Rats, Wistar; Time Factors; Vanadates | 1995 |
[Effects of vanadate on glucose metabolism in the lens of rats with streptozotocin-induced diabetes--ketohexokinase and aldolase activity].
Topics: Animals; Diabetes Mellitus, Experimental; Fructokinases; Fructose; Fructose-Bisphosphate Aldolase; Glycolysis; Lens, Crystalline; Male; Rats; Rats, Sprague-Dawley; Streptozocin; Vanadates | 1995 |
Relationship between reduction in food intake and amelioration of hyperglycemia by oral vanadate in STZ-induced diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diet, Reducing; Hyperglycemia; Hypoglycemic Agents; Rats; Vanadates | 1994 |
Vanadate action on renal phosphate transport.
Topics: Acid-Base Equilibrium; Animals; Diabetes Mellitus, Experimental; Drinking Behavior; Feeding Behavior; Kidney; Male; Parathyroidectomy; Phosphates; Rats; Rats, Sprague-Dawley; Vanadates | 1994 |
Insulin-like effects of vanadate on rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase mRNA and protein inductions in diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Insulin; Liver; Phosphofructokinase-2; Phosphoric Monoester Hydrolases; Phosphotransferases (Alcohol Group Acceptor); Protein Biosynthesis; Rats; RNA, Messenger; Vanadates | 1994 |
Improvement of mild hypoinsulinaemic diabetes in the rat by low non-toxic doses of vanadate.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Drug Administration Schedule; Energy Intake; Insulin; Male; Pancreas; Rats; Rats, Wistar; Vanadates; Weight Gain | 1994 |
Effect of vanadate on reproductive efficiency in normal and streptozocin-treated diabetic rats.
Topics: Administration, Oral; Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Female; Pregnancy; Pregnancy in Diabetics; Rats; Rats, Sprague-Dawley; Reproduction; Vanadates | 1994 |
Comparison of the effects of various vanadium salts on glucose homeostasis in streptozotocin-diabetic rats.
Topics: Analysis of Variance; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal; Glycosuria; Homeostasis; Insulin; Male; Rats; Rats, Wistar; Streptozocin; Vanadates; Vanadium Compounds | 1994 |
Vanadate treatment restores the expression of genes for key enzymes in the glucose and ketone bodies metabolism in the liver of diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; CCAAT-Enhancer-Binding Proteins; Diabetes Mellitus, Experimental; DNA-Binding Proteins; Gene Expression; Glucokinase; Glucose; Hydroxymethylglutaryl-CoA Synthase; Ketone Bodies; Liver; Male; Mitochondria, Liver; Monosaccharide Transport Proteins; Nuclear Proteins; Phosphoenolpyruvate Carboxykinase (GTP); Pyruvate Kinase; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tyrosine Transaminase; Vanadates | 1993 |
Insulin-mimetic effects of vanadate in preventing the increase of P450IIIA and P450IA subfamily proteins in streptozotocin-diabetic rats.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Experimental; Enzyme Induction; Insulin; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Rats; Rats, Inbred Strains; Vanadates | 1993 |
The effect of vanadate on selected mRNA abundance in streptozotocin-diabetic rat liver.
Topics: Animals; Diabetes Mellitus, Experimental; Insulin; Liver; Male; Phenylalanine Hydroxylase; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Wistar; Reference Values; RNA, Messenger; Vanadates | 1993 |
Effects of chronic vanadate administration in the STZ-induced diabetic rat. The antihyperglycemic action of vanadate is attributable entirely to its suppression of feeding.
Topics: Animals; Appetite; Appetite Depressants; Blood Glucose; Diabetes Mellitus, Experimental; Drinking Behavior; Feeding Behavior; Hypoglycemic Agents; Hypothalamus; Insulin; Male; Neuropeptides; Rats; Rats, Wistar; Reference Values; Vanadates | 1994 |
Effect of sodium orthovanadate on the hepatobiliary clearance of rose bengal in streptozotocin-induced diabetic rats.
Topics: Animals; Bile Acids and Salts; Bile Ducts; Diabetes Mellitus, Experimental; Insulin; Liver; Male; Rats; Rats, Sprague-Dawley; Rose Bengal; Streptozocin; Vanadates | 1993 |
The protein tyrosine phosphatase inhibitor, pervanadate, is a powerful antidiabetic agent in streptozotocin-treated diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Osmolar Concentration; Protein Tyrosine Phosphatases; Rats; Rats, Wistar; Time Factors; Vanadates | 1994 |
Oral vanadate and Tiron in treatment of diabetes mellitus in rats: improvement of glucose homeostasis and negative side-effects.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Administration, Oral; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Drinking; Drug Interactions; Drug Therapy, Combination; Eating; Homeostasis; Male; Rats; Rats, Sprague-Dawley; Tissue Distribution; Vanadates; Vanadium | 1993 |
[Effects of vanadate on glucose metabolism of the streptozotocin-diabetic rat lens].
Topics: Administration, Oral; Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Fructose; Glucose; L-Iditol 2-Dehydrogenase; Lens, Crystalline; Male; Rats; Rats, Sprague-Dawley; Sorbitol; Streptozocin; Vanadates | 1993 |
The effect of vanadate on alloxan-diabetic rat atria.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Insulin; Isoproterenol; Male; Myocardial Contraction; Rats; Reference Values; Thyroxine; Triiodothyronine; Vanadates | 1993 |
Effects of vanadate administration on the high sucrose diet-induced aberrations in normal rats.
Topics: Animals; Apolipoproteins B; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Insulin; Insulin Resistance; Liver; Male; Rats; Rats, Sprague-Dawley; Sucrose; Triglycerides; Vanadates | 1993 |
Effects of high sucrose diet on insulin-like effects of vanadate in diabetic rats.
Topics: Animals; Apolipoproteins B; Cholesterol; Diabetes Mellitus, Experimental; Dietary Carbohydrates; Insulin; Liver; Male; Rats; Rats, Sprague-Dawley; Streptozocin; Sucrose; Triglycerides; Vanadates | 1993 |
Insulin like effects of lithium and vanadate on the altered antioxidant status of diabetic rats.
Topics: Animals; Catalase; Diabetes Mellitus, Experimental; Drug Synergism; Glutathione; Glutathione Peroxidase; Insulin; Kidney; Lithium; Liver; Male; Oxidation-Reduction; Rats; Rats, Wistar; Superoxide Dismutase; Vanadates | 1993 |
In vivo antidiabetic actions of naglivan, an organic vanadyl compound in streptozotocin-induced diabetes.
Topics: Animals; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Glycated Hemoglobin; Heart; Hypoglycemic Agents; In Vitro Techniques; Insulin; Male; Myocardial Contraction; Rats; Rats, Wistar; Time Factors; Triglycerides; Vanadates | 1993 |
Elevated N-myristoyl transferase activity is reversed by sodium orthovanadate in streptozotocin-induced diabetic rat.
Topics: Acyltransferases; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Enzyme Activation; Insulin; Liver; Male; Rats; Rats, Sprague-Dawley; Vanadates | 1993 |
Impaired antioxidant status in diabetic rat liver. Effect of vanadate.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Glutathione; Insulin; Liver; Male; Rats; Rats, Wistar; Vanadates | 1993 |
Vanadate treatment of diabetic rats reverses the impaired expression of genes involved in hepatic glucose metabolism: effects on glycolytic and gluconeogenic enzymes, and on glucose transporter GLUT2.
Topics: Animals; Blood Glucose; Blotting, Northern; Diabetes Mellitus, Experimental; Gene Expression; Glucokinase; Gluconeogenesis; Glucose Transporter Type 2; Glycolysis; Liver; Male; Monosaccharide Transport Proteins; Phosphoenolpyruvate Carboxykinase (GTP); Pyruvate Kinase; Rats; Rats, Wistar; RNA, Messenger; Vanadates | 1993 |
The effect of oral vanadyl treatment on the reactivity of tracheal smooth muscle obtained from insulin-dependent diabetic rats.
Topics: Acetylcholine; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Male; Muscle, Smooth; Potassium Chloride; Rats; Trachea; Vanadates | 1993 |
Insulin-like effects of bis-glycinato oxovanadium (IV) complex on experimental diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glycine; Insulin; Lipids; Liver; Male; Rats; Rats, Wistar; Vanadates | 1993 |
Phlorizin or vanadate treatment reverses impaired expression of albumin and hepatocyte nuclear factor 1 in diabetic rats.
Topics: Animals; Base Sequence; Binding Sites; Blood Glucose; Diabetes Mellitus, Experimental; DNA-Binding Proteins; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Liver; Male; Molecular Sequence Data; Nuclear Proteins; Oligodeoxyribonucleotides; Phlorhizin; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Reference Values; RNA, Messenger; Serum Albumin; Suppression, Genetic; Transcription Factors; Transcription, Genetic; Vanadates; Vanadium Compounds | 1996 |
Insulin-like effects of vanadate and selenate on the expression of glucose-6-phosphate dehydrogenase and fatty acid synthase in diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Fatty Acids; Gene Expression; Glucosephosphate Dehydrogenase; Hypoglycemic Agents; Insulin; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Selenic Acid; Selenium Compounds; Vanadates; Weight Gain | 1995 |
Effects of vanadate and insulin on the activities of selected enzymes of amino acid metabolism in alloxan diabetic rat kidney.
Topics: Alanine Transaminase; Alloxan; Amino Acids; Animals; Arginase; Aspartate Aminotransferases; Diabetes Mellitus, Experimental; Female; Glutamate Dehydrogenase; Insulin; Kidney; Rats; Rats, Wistar; Vanadates | 1996 |
Effects of bis(maltolato)oxovanadium(IV) are distinct from food restriction in STZ-diabetic rats.
Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Cholesterol; Diabetes Mellitus, Experimental; Food Deprivation; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Pyrones; Rats; Rats, Wistar; Triglycerides; Vanadates | 1997 |
Acute and chronic response to vanadium following two methods of streptozotocin-diabetes induction.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Pyrones; Rats; Rats, Sprague-Dawley; Rats, Wistar; Streptozocin; Triglycerides; Vanadates; Vanadium Compounds | 1997 |
Insulin-like effects on liver Golgi membrane preparations of bis(oxalato)oxovanadate(IV) complex ion, a new vanadate compound.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Galactose; Galactosyltransferases; Golgi Apparatus; Insulin; Intracellular Membranes; Liver; Oxalates; Rats; Rats, Wistar; Vanadates; Vanadium | 1997 |
Differential effect of vanadate on receptor-mediated endocytosis of the asialoglycoprotein receptor in hepatocytes from normal and diabetic rats.
Topics: Animals; Asialoglycoprotein Receptor; Asialoglycoproteins; Blood Glucose; Body Weight; Cells, Cultured; Diabetes Mellitus, Experimental; Endocytosis; Ligands; Liver; Male; Orosomucoid; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Vanadates | 1997 |
Effects of oral vanadyl treatment on diabetes-induced alterations in the heart GLUT-4 transporter.
Topics: 4-Nitrophenylphosphatase; Administration, Oral; Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Glucose Transporter Type 4; Male; Monosaccharide Transport Proteins; Muscle Proteins; Myocardium; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sarcolemma; Triglycerides; Vanadates | 1997 |
Effect of peroxovanadate compound on phosphoenolpyruvate carboxykinase gene expression and lipid metabolism in diabetic rats.
Topics: Analysis of Variance; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Gene Expression Regulation, Enzymologic; Hypoglycemic Agents; Insulin; Lipid Metabolism; Liver; Metformin; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Sprague-Dawley; Streptozocin; Vanadates | 1997 |
[Hypoglycemic effects of peroxovanadate complexes on glucose transportor of diabetic rats].
Topics: Animals; Biological Transport; Blood Glucose; Diabetes Mellitus, Experimental; Female; Glucose; Humans; Hypoglycemic Agents; Male; Middle Aged; Nicotinic Acids; Rats; Rats, Sprague-Dawley; Vanadates | 1997 |
Effects of peroxovanadate complexes on reducing glycemia in diabetic rats and translocation of glucose transporter.
Topics: Animals; Biological Transport; Blood Glucose; Chelating Agents; Diabetes Mellitus, Experimental; Female; Hypoglycemic Agents; Male; Niacin; Rats; Rats, Sprague-Dawley; Vanadates | 1997 |
Fructose uptake in rat adipocytes: GLUT5 expression and the effects of streptozotocin-induced diabetes.
Topics: 3-O-Methylglucose; Adipocytes; Adipose Tissue; Animals; Biological Transport; Blood Glucose; Cell Membrane; Cells, Cultured; Cytochalasin B; Diabetes Mellitus, Experimental; Epididymis; Fructose; Gene Expression Regulation; Glucose Transporter Type 1; Glucose Transporter Type 4; Glucose Transporter Type 5; Insulin; Kinetics; Male; Monosaccharide Transport Proteins; Muscle Proteins; Rats; Rats, Sprague-Dawley; Vanadates | 1998 |
Insulin and vanadate restore decreased plasma endothelin concentrations and exaggerated vascular responses to normal in the streptozotocin diabetic rat.
Topics: Animals; Aorta; Blood Glucose; Diabetes Mellitus, Experimental; Endothelin-1; Insulin; Male; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Vanadates; Vasoconstrictor Agents | 1998 |
Influence of bis(maltolato)oxovanadium(IV) on activity of galactosyltransferase (GalT) and morphology of rat liver Golgi apparatus in control and streptozotocin diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Female; Galactosyltransferases; Golgi Apparatus; Hypoglycemic Agents; Liver; Microscopy, Electron; Pyrones; Rats; Rats, Wistar; Streptozocin; Vanadates | 1998 |
Hexokinase, glucose-6-phosphate dehydrogenase and antioxidant enzymes in diabetic reticulocytes: effects of insulin and vanadate.
Topics: Animals; Catalase; Diabetes Mellitus, Experimental; Glucosephosphate Dehydrogenase; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Hexokinase; Insulin; Male; Peroxidases; Rats; Rats, Wistar; Reference Values; Reticulocytes; Superoxide Dismutase; Vanadates | 1998 |
Treatment of streptozotocin-induced diabetic rats with vanadate and phlorizin prevents the over-expression of the liver insulin receptor gene.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Gene Expression; Insulin; Liver; Male; Phlorhizin; Rats; Rats, Wistar; Receptor, Insulin; RNA, Messenger; Subcellular Fractions; Tumor Cells, Cultured; Vanadates | 1999 |
Effects of vanadium complexes with organic ligands on glucose metabolism: a comparison study in diabetic rats.
Topics: Administration, Oral; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Disinfectants; Glucokinase; Glucose; Hydroxybutyrates; Hypoglycemic Agents; Injections, Intraperitoneal; Insulin; Islets of Langerhans; Ligands; Liver; Liver Glycogen; Male; Muscles; Organometallic Compounds; Pentanones; Phosphoenolpyruvate Carboxykinase (GTP); Pyrones; Pyruvate Kinase; Rats; Rats, Wistar; RNA, Messenger; Time Factors; Vanadates; Vanadium Compounds | 1999 |
Synergistic interaction of magnesium and vanadate on glucose metabolism in diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Synergism; Glucose Clamp Technique; Glycogen; Glycolysis; Hypoglycemic Agents; Magnesium Compounds; Male; Rats; Rats, Sprague-Dawley; Vanadates | 1999 |
Modulation of mRNA levels of liver arginase by insulin and vanadate in experimental diabetes.
Topics: Animals; Arginase; Diabetes Mellitus, Experimental; Female; Insulin; Liver; Rats; Rats, Wistar; RNA, Messenger; Vanadates | 1999 |
Change in the lipid profile, lipogenic and related enzymes in the livers of experimental diabetic rats: effect of insulin and vanadate.
Topics: Animals; Cholesterol; Cytosol; Diabetes Mellitus, Experimental; Female; Glucose-6-Phosphatase; Hexokinase; Homeostasis; Hypoglycemic Agents; Insulin; Isoenzymes; Lipid Metabolism; Liver; Malate Dehydrogenase; Rats; Rats, Wistar; Triglycerides; Vanadates | 1999 |
Vanadyl-biguanide complexes as potential synergistic insulin mimics.
Topics: Animals; Biguanides; Blood Glucose; Diabetes Mellitus, Experimental; Drug Synergism; Humans; Hypoglycemic Agents; In Vitro Techniques; Insulin; Male; Metformin; Phenformin; Rats; Rats, Wistar; Vanadates | 1999 |
Effect of antidiabetic compounds on glyoxalase I activity in experimental diabetic rat liver.
Topics: Animals; Diabetes Mellitus, Experimental; Female; Hypoglycemic Agents; Lactoylglutathione Lyase; Liver; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Trigonella; Vanadates | 1999 |
Modulation of some gluconeogenic enzyme activities in diabetic rat liver and kidney: effect of antidiabetic compounds.
Topics: Animals; Diabetes Mellitus, Experimental; Female; Fructose-Bisphosphatase; Gluconeogenesis; Glucose-6-Phosphatase; Hypoglycemic Agents; Insulin; Kidney; Liver; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Trigonella; Vanadates | 1999 |
Effects of vanadate, insulin and fenugreek (Trigonella foenum graecum) on creatine kinase levels in tissues of diabetic rat.
Topics: Animals; Creatine Kinase; Diabetes Mellitus, Experimental; Female; Hypoglycemic Agents; Insulin; Liver; Muscle, Skeletal; Myocardium; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Trigonella; Vanadates | 1999 |
Effects of bis(maltolato) oxovanadium (IV) on protein serine kinases in skeletal muscle of streptozotocin-diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Insulin; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Protein Serine-Threonine Kinases; Pyrones; Rats; Rats, Wistar; Vanadates | 1999 |
Effects of vanadate on expression of liver arginase in experimental diabetic rats.
Topics: Animals; Arginase; Cytosol; Diabetes Mellitus, Experimental; Female; Gene Expression; Insulin; Liver; Rats; Rats, Wistar; RNA, Messenger; Vanadates | 1999 |
An orally active antidiabetic vanadyl complex, bis(1-oxy-2-pyridinethiolato)oxovanadium(IV), with VO(S2O2) coordination mode; in vitro and in vivo evaluations in rats.
Topics: Adipocytes; Administration, Oral; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Evaluation; Electron Spin Resonance Spectroscopy; Fatty Acids, Nonesterified; Half-Life; Hypoglycemic Agents; Injections, Intravenous; Insulin; Male; Molecular Structure; Rats; Rats, Wistar; Vanadates | 2000 |
Vanadate restores glucose 6-phosphate in diabetic rats: a mechanism to enhance glucose metabolism.
Topics: Adipose Tissue; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucose; Glucose-6-Phosphate; Insulin; Lipids; Liver; Male; Muscle, Skeletal; Phlorhizin; Rats; Rats, Wistar; Streptozocin; Vanadates | 2000 |
Effect of peroxovanadate compound on phenylalanine hydroxylase gene expression.
Topics: Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Gene Expression; Hypoglycemic Agents; Insulin; Lipid Metabolism; Liver; Phenylalanine Hydroxylase; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triglycerides; Vanadates | 2000 |
Agouti-related protein is a mediator of diabetic hyperphagia.
Topics: Agouti-Related Protein; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Drinking; Eating; Enzyme Inhibitors; Hyperphagia; Hypothalamus; Insulin; Intercellular Signaling Peptides and Proteins; Leptin; Male; Neuropeptide Y; Protein Tyrosine Phosphatases; Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vanadates | 2001 |
Chemistry and insulin-mimetic properties of bis(acetylacetonate)oxovanadium(IV) and derivatives.
Topics: Animals; Blood Glucose; Crystallography, X-Ray; Diabetes Mellitus, Experimental; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Insulin; Magnetic Resonance Spectroscopy; Male; Molecular Mimicry; Molecular Structure; Organometallic Compounds; Rats; Rats, Wistar; Streptozocin; Structure-Activity Relationship; Vanadates | 2000 |
In vivo effects of vanadium on GLUT4 translocation in cardiac tissue of STZ-diabetic rats.
Topics: Animals; Blood Glucose; Cell Membrane; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Glucose Transporter Type 4; Insulin; Male; Monosaccharide Transport Proteins; Muscle Proteins; Myocardium; Ouabain; Protein Transport; Pyrones; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Vanadates | 2001 |
A new halogenated antidiabetic vanadyl complex, bis(5-iodopicolinato)oxovanadium(IV): in vitro and in vivo insulinomimetic evaluations and metallokinetic analysis.
Topics: Adipose Tissue; Animals; Blood Circulation; Blood Glucose; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Erythrocytes; Fatty Acids, Nonesterified; Hypoglycemic Agents; Inhibitory Concentration 50; Iodine; Ligands; Metabolic Clearance Rate; Organometallic Compounds; Picolinic Acids; Rats; Rats, Wistar; Spectrum Analysis; Streptozocin; Tissue Distribution; Vanadates | 2001 |
Lack of in vivo effect of vanadium on GLUT4 translocation in white adipose tissue of streptozotocin-diabetic rats.
Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Cell Membrane; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin; Male; Monosaccharide Transport Proteins; Muscle Proteins; Pyrones; Rats; Rats, Wistar; Time Factors; Vanadates; Vanadium | 2001 |
Combined treatment with benzylamine and low dosages of vanadate enhances glucose tolerance and reduces hyperglycemia in streptozotocin-induced diabetic rats.
Topics: Adipocytes; Animals; Benzylamines; Biological Transport; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Glucose; Glucose Intolerance; Glucose Transporter Type 4; Hyperglycemia; Male; Monosaccharide Transport Proteins; Muscle Proteins; Rats; Rats, Wistar; Semicarbazides; Vanadates | 2001 |
In vivo effects of vanadium in diabetic rats are independent of changes in PI-3 kinase activity in skeletal muscle.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Insulin; Male; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Pyrones; Rats; Rats, Wistar; Rats, Zucker; Signal Transduction; Vanadates | 2001 |
In vivo effects of insulin and bis(maltolato)oxovanadium (IV) on PKB activity in the skeletal muscle and liver of diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose Tolerance Test; Insulin; Liver; Male; Muscle, Skeletal; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrones; Random Allocation; Rats; Rats, Wistar; Rats, Zucker; Tissue Extracts; Vanadates | 2001 |
Bis(6-ethylpicolinato)oxovanadium(IV) complex with normoglycemic activity in KK-A(y) mice.
Topics: Adipocytes; Animals; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Glucose Tolerance Test; Hypoglycemic Agents; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Molecular Structure; Organometallic Compounds; Picolinic Acids; Rats; Structure-Activity Relationship; Vanadates | 2002 |
Influence of sodium bis(oxalato)oxovanadate(IV) on phospholipids in liver Golgi fractions from control and streptozotocin-diabetic rats.
Topics: Animals; Biomarkers; Diabetes Mellitus, Experimental; Female; Galactosyltransferases; Golgi Apparatus; In Vitro Techniques; Liver; Membranes; Oxalates; Phospholipids; Rats; Rats, Wistar; Vanadates | 2000 |
Effect of chronic treatment with Bis(maltolato)oxovanadium (IV) in rat model of non-insulin-dependent-diabetes.
Topics: Animals; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose Tolerance Test; Hypercholesterolemia; Hypoglycemic Agents; Insulin; Male; Pyrones; Rats; Rats, Wistar; Vanadates | 2001 |
Effect of oxovanadium(IV) complexes on nondiabetic and streptozotocin-diabetic rats.
Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Lipids; Male; Organometallic Compounds; Rats; Rats, Wistar; Streptozocin; Structure-Activity Relationship; Vanadates | 2001 |
Vanadium increases GLUT4 in diabetic rat skeletal muscle.
Topics: Animals; Diabetes Mellitus, Experimental; DNA Primers; Glucose Transporter Type 4; Hypoglycemic Agents; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Pyrones; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Up-Regulation; Vanadates | 2002 |
Differential tissue regulation of insulin-like growth factor binding proteins in experimental diabetes mellitus in the rat.
Topics: Animals; Brain; Carrier Proteins; Cerebral Cortex; Cross-Linking Reagents; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamide Gel; Hypothalamus; Insulin; Insulin-Like Growth Factor Binding Protein 1; Kidney; Liver; Male; Molecular Weight; Organ Specificity; Phlorhizin; Pituitary Gland; Rats; Rats, Sprague-Dawley; Reference Values; Somatomedins; Succinimides; Vanadates | 1992 |
Effect of vanadate on tryptophan metabolism in streptozotocin diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Kidney; Liver; Rats; Rats, Wistar; Vanadates | 1992 |
Oral administration of vanadate to diabetic rats restores liver 6-phosphofructo-2-kinase content and mRNA.
Topics: Administration, Oral; Animals; Blood Glucose; Cytosol; Diabetes Mellitus, Experimental; Immunoassay; Isoenzymes; Liver; Male; Phosphofructokinase-2; Phosphotransferases; Pyruvate Kinase; Rats; Rats, Inbred Strains; Reference Values; RNA, Messenger; Vanadates | 1992 |
The effect of vanadate upon the expression of phenylalanine hydroxylase in streptozotocin-diabetic rat liver.
Topics: Animals; Blotting, Northern; Blotting, Western; Cells, Cultured; Diabetes Mellitus, Experimental; Glucagon; Hydroxylation; Liver; Male; Phenylalanine Hydroxylase; Phosphorylation; Rats; Rats, Wistar; RNA; Streptozocin; Vanadates | 1992 |
Vanadate treatment increases the activity of glycolytic enzymes and raises fructose 2,6-bisphosphate concentration in hearts from diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Fructosediphosphates; Glycolysis; Heart; Hexokinase; Isoenzymes; Male; Myocardium; Phosphofructokinase-1; Pyruvate Kinase; Rats; Rats, Wistar; Vanadates | 1992 |
Effects of vanadate on glycolytic enzymes and malic enzyme in insulin-dependent and -independent tissues of diabetic rats.
Topics: Animals; Body Weight; Diabetes Mellitus, Experimental; Hexokinase; Insulin; Kidney; Liver; Malate Dehydrogenase; Male; Pyruvate Kinase; Radioimmunoassay; Rats; Rats, Inbred Strains; Vanadates | 1992 |
Tiron administration minimizes the toxicity of vanadate but not its insulin mimetic properties in diabetic rats.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Injections, Intraperitoneal; Insulin; Kidney; Male; Rats; Rats, Inbred Strains; Streptozocin; Vanadates | 1992 |
Biosynthesis of cholic acid accelerated by diabetes: its mechanism and effect of vanadate administration.
Topics: Animals; Bile; Bile Acids and Salts; Cholic Acid; Cholic Acids; Diabetes Mellitus, Experimental; Male; Rats; Rats, Inbred Strains; Vanadates | 1992 |
Bis(maltolato)oxovanadium(IV) is a potent insulin mimic.
Topics: Animals; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Male; Organometallic Compounds; Pyrones; Rats; Rats, Inbred Strains; Vanadates | 1992 |
Lipoprotein lipase release from cardiac myocytes is increased by decavanadate but not insulin.
Topics: Animals; Cell Separation; Diabetes Mellitus, Experimental; Glucose; Heparin; In Vitro Techniques; Insulin; Lipoprotein Lipase; Male; Myocardium; Oxidation-Reduction; Perfusion; Protein Biosynthesis; Rats; Rats, Inbred Strains; Reference Values; Vanadates | 1992 |
Effect of vanadate administration on polyol pathway in diabetic rat kidney.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Insulin; Kidney; Kidney Cortex; Kidney Medulla; L-Iditol 2-Dehydrogenase; Male; Rats; Rats, Inbred Strains; Sorbitol; Vanadates | 1992 |
The effects of orthovanadate, vanadyl and peroxides of vanadate on glucose metabolism in skeletal muscle preparations in vitro.
Topics: Animals; Diabetes Mellitus, Experimental; Glucose; Glycogen; Insulin; Lactates; Lactic Acid; Male; Muscles; Rats; Rats, Inbred Strains; Vanadates | 1992 |
Insulinlike effects of zinc ion in vitro and in vivo. Preferential effects on desensitized adipocytes and induction of normoglycemia in streptozocin-induced rats.
Topics: Adipose Tissue; Animals; Biological Assay; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Experimental; Glucose; Hydrogen Peroxide; Insulin; Lipid Metabolism; Male; Rats; Rats, Inbred Strains; Vanadates; Zinc | 1992 |
A comparative study of the microsomal S6 phosphatase and phosphorylase phosphatase activities in rat liver.
Topics: Animals; Diabetes Mellitus, Experimental; Endoplasmic Reticulum; In Vitro Techniques; Insulin; Male; Microsomes, Liver; Phosphoprotein Phosphatases; Phosphorylase Phosphatase; Rats; Rats, Inbred BUF; Rats, Inbred Strains; Vanadates | 1991 |
Differential effects of diabetes on adipocyte and liver phosphotyrosine and phosphoserine phosphatase activities.
Topics: Adipose Tissue; Animals; Cytosol; Diabetes Mellitus, Experimental; Ethers, Cyclic; Glycogen Synthase; Insulin; Kinetics; Liver; Macromolecular Substances; Male; Okadaic Acid; Phosphoric Monoester Hydrolases; Protein Tyrosine Phosphatases; Rats; Rats, Inbred Strains; Receptor, Insulin; Reference Values; Vanadates | 1991 |
Vanadate induction of pancreatic amylase mRNA in diabetic rats.
Topics: Amylases; Animals; Diabetes Mellitus, Experimental; Hyperglycemia; Male; Pancreas; Rats; Rats, Inbred Strains; RNA, Messenger; Vanadates | 1990 |
Antidiabetic action of vanadyl in rats independent of in vivo insulin-receptor kinase activity.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Kinetics; Liver; Male; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Reference Values; Vanadates | 1991 |
Improvement of glucose homeostasis by oral vanadyl or vanadate treatment in diabetic rats is accompanied by negative side effects.
Topics: Administration, Oral; Animals; Diabetes Mellitus, Experimental; Glucose; Homeostasis; Male; Rats; Rats, Inbred Strains; Vanadates | 1991 |
Effect of vanadate on the metabolism of bile acids in diabetic rats.
Topics: Animals; Bile; Bile Acids and Salts; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Male; Rats; Rats, Inbred Strains; Vanadates | 1991 |
Effect of vanadate on renal hypertrophy and sorbitol accumulation in streptozotocin induced diabetes in rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Hypertrophy; Inositol; Kidney; Male; Organ Size; Rats; Rats, Inbred Strains; Sorbitol; Vanadates | 1991 |
Insulin mimetic role of vanadate on plasma membrane insulin-receptors.
Topics: Animals; Cell Membrane; Diabetes Mellitus, Experimental; Insulin; Liver; Male; Rats; Rats, Inbred Strains; Receptor, Insulin; Vanadates | 1991 |
Effects of vanadate on plasma lipoprotein profiles in experimental diabetic rats.
Topics: Animals; Cholesterol; Diabetes Mellitus, Experimental; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Phospholipids; Rats; Rats, Inbred Strains; Triglycerides; Vanadates | 1991 |
Activation by vanadate of glycolysis in hepatocytes from diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Fructosediphosphates; Glycolysis; In Vitro Techniques; Liver; Male; Rats; Rats, Inbred Strains; Vanadates | 1991 |
Abnormal B-cell function in rats with non-insulin-dependent diabetes induced by neonatal streptozotocin: effect of in vivo insulin, phlorizin, or vanadate treatments.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Male; Pancreas; Phlorhizin; Rats; Rats, Inbred Strains; Vanadates | 1991 |
Insulin-like effect of vanadate on malic enzyme and glucose-6-phosphate dehydrogenase activities in streptozotocin-induced diabetic rat liver.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Glucosephosphate Dehydrogenase; Insulin; Liver; Malate Dehydrogenase; Male; Rats; Rats, Inbred Strains; Vanadates | 1991 |
Oral administration of vanadate to streptozotocin-diabetic rats restores the glucose-induced activation of liver glycogen synthase.
Topics: Animals; Diabetes Mellitus, Experimental; Enzyme Activation; Glucokinase; Glucose; Glycogen Synthase; Glycogen-Synthase-D Phosphatase; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Vanadates | 1990 |
Insulinlike effects of vanadate on hepatic glycogen metabolism in nondiabetic and streptozocin-induced diabetic rats.
Topics: Alanine Transaminase; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Glucagon; Glycogen-Synthase-D Phosphatase; Insulin; Liver; Liver Glycogen; Phosphorylase Kinase; Phosphorylase Phosphatase; Protein Kinases; Rats; Rats, Inbred Strains; Reference Values; Vanadates; Vanadium | 1990 |
Effect of in vivo vanadate treatment on insulin receptor tyrosine kinase activity in partially pancreatectomized diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Insulin; Liver; Male; Osmolar Concentration; Pancreatectomy; Phlorhizin; Phosphoric Monoester Hydrolases; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Vanadates | 1990 |
Impaired insulin action but normal insulin receptor activity in diabetic rat liver: effect of vanadate.
Topics: Animals; Blood Glucose; Cell Membrane; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Insulin; Insulin Resistance; Liver; Liver Glycogen; Phosphoenolpyruvate Carboxykinase (GTP); Phosphorylation; Rats; Rats, Inbred Strains; Receptor, Insulin; Reference Values; Vanadates | 1990 |
Enhanced in vivo sensitivity of vanadyl-treated diabetic rats to insulin.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Insulin; Male; Rats; Rats, Inbred Strains; Vanadates | 1990 |
Vanadate treatment of streptozotocin diabetic rats restores expression of the insulin-responsive glucose transporter in skeletal muscle.
Topics: Animals; Base Sequence; Diabetes Mellitus, Experimental; DNA Probes; Gene Expression; Immunoblotting; Insulin; Insulin Infusion Systems; Male; Molecular Sequence Data; Monosaccharide Transport Proteins; Muscles; Nucleic Acid Hybridization; Rats; RNA, Messenger; Vanadates | 1990 |
Insulinomimetic properties of trace elements and characterization of their in vivo mode of action.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Glucose; Glycogen; Glycolysis; Insulin; Lactates; Lithium; Male; Muscles; Pancreatectomy; Rats; Rats, Inbred Strains; Reference Values; Vanadates | 1990 |
Marked improvement of glucose homeostasis in diabetic ob/ob mice given oral vanadate.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucose; Glucose Tolerance Test; Homeostasis; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Resistance; Mice; Mice, Obese; Vanadates | 1990 |
Decrease of liver protein kinase C in streptozotocin-induced diabetic rats and restoration by vanadate treatment.
Topics: Animals; Diabetes Mellitus, Experimental; Female; Liver; Phosphorylation; Protein Kinase C; Proteins; Rats; Rats, Inbred Strains; Vanadates | 1990 |
Toxic effects of vanadium in streptozotocin-treated rats after administration of vanadate to normalize blood glucose levels.
Topics: Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Rats; Vanadates | 1990 |
Effect of vanadate administration on blood glucose and insulin levels as well as on the exocrine pancreatic function in streptozotocin-diabetic rats.
Topics: Amylases; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Insulin; Insulin Secretion; Islets of Langerhans; Male; Microscopy, Electron; Pancreas; Rats; Rats, Inbred Strains; Reference Values; Vanadates | 1989 |
Control of glycogen synthase and phosphorylase in hepatocytes from diabetic rats. Effects of glucagon, vasopressin, and vanadate.
Topics: Animals; Arginine Vasopressin; Calcium; Diabetes Mellitus, Experimental; Glucagon; Glycogen Synthase; Kinetics; Liver; Male; Phosphorylases; Rats; Rats, Inbred Strains; Reference Values; Vanadates | 1989 |
Correction of chronic hyperglycemia with vanadate, but not with phlorizin, normalizes in vivo glycogen repletion and in vitro glycogen synthase activity in diabetic skeletal muscle.
Topics: Animals; Chronic Disease; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose Clamp Technique; Glycogen; Glycogen Synthase; Hyperglycemia; Insulin; Liver; Male; Muscles; Phlorhizin; Rats; Rats, Inbred Strains; Vanadates | 1989 |
Hepatic phosphotyrosine phosphatase activity and its alterations in diabetic rats.
Topics: Animals; Cytosol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Insulin; Liver; Male; Phosphoprotein Phosphatases; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Rats; Rats, Inbred BB; Rats, Inbred Strains; Receptor, Insulin; Vanadates | 1989 |
In vivo insulin resistance in streptozotocin-diabetic rats--evidence for reversal following oral vanadate treatment.
Topics: Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Glucose; Insulin; Insulin Resistance; Rats; Rats, Inbred Strains; Reference Values; Vanadates | 1989 |
Long-term effects of vanadyl treatment on streptozocin-induced diabetes in rats.
Topics: Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Inbred Strains; Vanadates | 1989 |
Reversal by vanadate of the effect of diabetes on intestinal growth and transport.
Topics: 3-O-Methylglucose; Aminoisobutyric Acids; Animals; Body Weight; Cell Division; Diabetes Mellitus, Experimental; Intestinal Absorption; Intestinal Mucosa; Male; Methylglucosides; Organ Size; Rats; Rats, Inbred Strains; Reference Values; Vanadates | 1989 |
Insulin-like effects of vanadate on glucokinase activity and fructose 2,6-bisphosphate levels in the liver of diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Fructosediphosphates; Glucokinase; Hexosediphosphates; Insulin; Liver; Liver Glycogen; Phosphofructokinase-2; Phosphotransferases; Vanadates | 1988 |
Suppression of the hepatic glucose-6-phosphatase system in diabetic rats by vanadate.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucose-6-Phosphatase; Hydrolysis; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Vanadates | 1988 |
Oral administration of vanadate normalizes blood glucose levels in streptozotocin-treated rats. Characterization and mode of action.
Topics: Adipose Tissue; Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Insulin; Kinetics; Lipid Metabolism; Male; Rats; Rats, Inbred Strains; Streptozocin; Vanadates; Vanadium | 1987 |
Long term improvement of glucose homeostasis by vanadate treatment in diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucose; Glucose Tolerance Test; Glycogen; Glycosuria; Homeostasis; Insulin; Islets of Langerhans; Liver; Liver Glycogen; Male; Muscles; Rats; Rats, Inbred Strains; Reference Values; Vanadates | 1988 |
Effects of vanadate and insulin on glucose 1,6-P2 and fructose 2,6-P2 levels in rat skeletal muscle.
Topics: Animals; Diabetes Mellitus, Experimental; Fructosediphosphates; Glucose-6-Phosphate; Glucosephosphates; Hexosediphosphates; Insulin; Male; Muscles; Rats; Rats, Inbred Strains; Vanadates | 1988 |
Vanadate substitutes insulin role in chronic experimental diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Insulin; Lactates; Liver; Liver Glycogen; Male; Pyruvates; Rats; Rats, Inbred Strains; Vanadates | 1988 |
Effect of vanadate on elevated blood glucose and depressed cardiac performance of diabetic rats.
Topics: Animals; Blood Glucose; Calcium-Transporting ATPases; Diabetes Mellitus, Experimental; Drinking; Female; Insulin; Myocardial Contraction; Myocardium; Rats; Rats, Inbred Strains; Sarcoplasmic Reticulum; Vanadates; Vanadium | 1985 |