valsartan has been researched along with Hypertension in 910 studies
*Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 47 (5.16) | 18.2507 |
| 2000's | 414 (45.49) | 29.6817 |
| 2010's | 364 (40.00) | 24.3611 |
| 2020's | 85 (9.34) | 2.80 |
| Authors | Studies |
|---|---|
| Schieffer, B; Schmidt, B | 1 |
| Chen, ZL; Da, YJ; Liang, LS; Nie, YY; Xin, T; Yan, YJ; Ye, Y; Yuan, WD | 1 |
| Crea, F | 1 |
| Cox, E; Ishigami, J; Miller, ER; Moran, AE; Pfister, M; Qin, L; Zhang, N | 1 |
| Gallo, G; Rubattu, S; Volpe, M | 1 |
| Nolan, T | 1 |
| Chan, TH; Tsoi, MF; Yung Cheung, BM | 1 |
| Gotou, H; Kario, K; Rakugi, H; Sasajima, T; Yamaguchi, M; Zhang, J | 1 |
| Ding, XX; Liu, BC; Tang, HX; Wang, B; Wang, GH; Zhang, XL; Zheng, J | 1 |
| Kozak, PM; Stacey, RB; Upadhya, B; Vasan, RS | 1 |
| Bian, Q; Guan, Y; Liu, H; Liu, Y | 1 |
| Chen, W; Hua, Z; Li, Y; Wang, Y; Zhu, Y | 1 |
| Du, H; Jiang, N; Li, X; Zhao, W | 1 |
| Chen, K; Gong, M; Jiang, Y; Li, W; Liu, R; Lv, W; Song, W; Xu, Y; Xu, Z; Yao, F; Yu, Q | 1 |
| Qi, M; Sun, R; Wang, W; Yi, G; Yu, J; Zhuang, C | 1 |
| Ohishi, M | 1 |
| Kario, K; Williams, B | 1 |
| Li, D; Liu, Q; Xie, Y; Yan, J | 1 |
| Chen, C; Fan, L; Li, J; Li, X; Lv, Q; Tian, D; Zuo, C | 2 |
| Jin, JC; Li, BN; Liu, KK; Liu, S; Wu, HX | 1 |
| Lozhkina, NG; Spiridonov, AN | 1 |
| Abdelkawy, M; El-Hanboushy, S; Fayez, YM; Lotfy, HM; Marzouk, HM | 1 |
| Chen, S; Kang, L; Liu, Y; Si, J; Xu, B; Zhong, C | 1 |
| Huang, J; Liu, J; Lou, Y; Yu, Y | 1 |
| Imamura, T; Kinugawa, K | 1 |
| Clahsen-van Groningen, MC; Cruz-López, EO; Danser, AHJ; Domenig, O; Foster, D; Garrelds, IM; Kasper, A; Nioi, P; Poglitsch, M; Ren, L; Rooney, T; Uijl, E; van Veghel, R; Zlatev, I | 1 |
| Chou, CL; Fang, TC; Li, CH | 1 |
| Bakris, GL; Salvador, VD | 1 |
| Huang, H; Li, M; Zhang, Y; Zhao, X | 1 |
| Chen, KJ; Chu, JF; Fu, CG; Long, LZ; Lu, Y; Peng, J; Qu, H; Yang, QN | 1 |
| Choi, Y; Chu, C; Hernandez, I; Magnani, JW; Santhireswaran, A; Suda, KJ; Tadrous, M | 1 |
| Fukushima, H; Horio, T; Ishimitsu, T; Iwashima, Y; Rai, T | 1 |
| Ahmad, A; Alama, MN; Alharthi, TS; Alkreathy, HM; Alluhabi, SI; Alqarni, F; Alrafiah, AR; Damanhouri, ZA | 1 |
| Chen, M; Fu, P; Gan, Y; He, X; He, Y; Jin, Y; Li, K; Liao, R; Liu, R; Qin, M; Wang, Z; Xue, H; Zhang, M; Zheng, L; Zhong, H; Zhou, X; Zou, H | 1 |
| Dodd, JD; Fox, R; Gallagher, J; Ledwidge, M; McDonald, K; McVeigh, N; Murphy, DJ; Ryan, F; Shorten, E; Sweeney, C; Watson, C; Zhou, S | 1 |
| Guo, Z; He, S; Li, J; Lu, Y; Peng, J; Shen, A; Wen, Y; Xie, Q; Yang, X; Zeng, W; Zhang, X | 1 |
| Cortés-Ríos, J; Rodriguez-Fernandez, M | 1 |
| Blettenberg, J; Böhm, M; Gillessen, A; Mevius, A; Predel, HG; Randerath, O; Schmieder, RE; Wassmann, S; Weisser, B; Wilke, T | 1 |
| Bolevich, S; Bradic, J; Filipovic, N; Govoruskina, N; Grujic, J; Jakovljevic, DG; Jakovljevic, V; Jeremic, J; Jeremic, N; MacGowan, G; Milivojevic, N; Milosavljevic, I; Nikolic Turnic, T; Okwose, N; Seklic, D; Srejovic, I; Tanaskovic, I; Velicki, L; Zivanovic, MN; Zivkovic, V | 1 |
| Abdelrahim, MEA; Hanna, SM; Mahmoud, HB; Rabea, HM | 1 |
| Almarjan, AI; Almarjan, SA; Masoud, AT | 1 |
| Su, F; Xia, Q | 1 |
| Eguchi, S; Iekushi, K; Kario, K; Morita, Y; Rakugi, H; Yarimizu, D | 1 |
| Beom, JW; Cho, YH; Jang, JY; Kang, SM; Kim, JS; Kim, WH; Lee, KJ; Ryu, JK; Shin, WY; Yoon, YW | 1 |
| Abraham, WT; Butt, JH; Desai, AS; Dewan, P; Dickstein, K; Ferreira, JP; Jhund, PS; Køber, L; McMurray, JJV; Packer, M; Petrie, MC; Rouleau, JL; Solomon, SD; Stewart, S; Swedberg, K; Zile, MR | 1 |
| Bradley, MC; Eworuke, E; Ghosh, RE; Hou, L; Jensen, PB; Lee, H; Maro, JC; Paterson, MJ; Pennap, D; Platt, RW; Pottegard, A; Rai, A; Scarnecchia, D; Shinde, M; Welburn, S; Woronow, D | 1 |
| Chen, J; Li, C; Liang, W; Pei, Y; Wang, Q; Yu, J | 1 |
| Akai, H; Munakata, Y; Numahata, T; Sawada, S; Tanji, Y; Watanabe, T | 1 |
| Bradley, M; Eworuke, E; Hedenmalm, K; Kurz, X; Lee, H; Quinten, C | 1 |
| Deng, CY; Deng, H; Fang, Y; Kuang, SJ; Li, LA; Li, Q; Li, QQ; Liu, Y; Peng, DW; Rao, F; Wei, W; Wu, SL; Xue, YM; Yang, H; Zeng, P; Zhang, MZ; Zhang, QH | 1 |
| Hirata, T; Ishii, T; Kokuba, S; Nakamura, K; Shiohira, H; Tayag, JCS | 1 |
| Heimark, S; Julius, S; Kjeldsen, SE; Larstorp, AC; Liestøl, K; Mancia, G; Mariampillai, JE; Mehlum, MH; Rostrup, M; Søraas, CL; Wachtell, K; Weber, MA | 1 |
| Liang, H; Tang, T; Xie, M | 1 |
| Hu, L; Liu, G; Wei, Y | 1 |
| Alarco, W; Figueroa, Y; Gómez-Mesa, JE; Magaña, A; Pow-Chon, F; Quesada, D; Ramos, CE; Rodríguez-García, D; Rossel, V; Saldarriaga, C; Speranza, M; Ventura-Umanzor, JR | 1 |
| Azizi, M; Hulot, JS; Rossignol, P | 1 |
| Austin, PC; Chong, A; Jackevicius, CA; Ko, DT; Koh, M; Krumholz, HM; Ozaki, AF; Udell, JA | 1 |
| Bianco, HT; Ferreira, CES; Figueiredo Neto, AM; Fonseca, FAH; França, CN; Izar, MCO; Kato, JT; Massunaga, ND; Póvoa, RMS | 1 |
| 't Hart, DC; Danser, AHJ; de Vries, R; Garrelds, IM; Groningen, MCC; Hoorn, EJ; Joles, JA; Nijenhuis, T; Roksnoer, LCW; Uijl, E; van der Vlag, J; van Veghel, R; Zietse, R | 1 |
| Fu, J; Liu, W; Liu, Y | 1 |
| Kario, K; Kurose, Y; Matsuda, S; Nagahama, S; Sugii, H; Suzuki, N; Teshima, T; Wakabayashi, M | 1 |
| Buus, NH; Grimm, D; Krüger, M; Simonsen, U; Wehland, M | 1 |
| Gorshunova, NK; Savich, VV | 1 |
| Cao, S; Huang, X; Jiang, X; Kang, Y; Mei, Q; Qin, D; Wu, AG; Wu, J; Yang, J; Ye, Y; Zhang, C | 1 |
| McAlister, FA; Youngson, E | 1 |
| Kario, K; Kurose, Y; Matsuda, S; Nagahama, S; Sugii, H; Suzuki, N; Teshima, T | 2 |
| Beaudoin, C; Blais, C; Guénette, L; Hamel, D; Leclerc, J; Poirier, P; Rochette, L | 1 |
| DeLeon-Pennell, KY; Domondon, M; Fitzgibbon, WR; Fox, R; Gooz, MB; Ilatovskaya, DV; Kashyrina, Y; Polina, I; Schibalski, RS; Sudarikova, AV; Troncoso, M; Vasileva, VY | 1 |
| Bartoletti, M; Viale, P | 1 |
| Tocci, G | 1 |
| Khairat, I; Khedr, L; Werida, R | 1 |
| Geng, Q; Hou, F; Wang, Z; Yan, R | 1 |
| Chen, LC; Chiang, CE; Leu, HB; Lu, TM; Wang, KL; Yu, WC | 1 |
| Sander, GE; Wang, SJ | 1 |
| Dong, Z; Li, G; Li, L; Liang, Y; Liu, E; Liu, T; Niu, X; Wang, J; Yang, Y; Zhao, Z | 1 |
| Abraham, I; Alkhatib, N; Brié, H; Denhaerynck, K; Hamarneh, D; MacDonald, K; Sun, D; Van Camp, Y; Vancayzeele, S; Villa, L | 1 |
| Bots, ML; Groenland, EH; Spiering, W; van der Elst, KCM; van Kleef, MEAM; Visseren, FLJ | 1 |
| Danser, AHJ; Domenig, O; Foster, D; Garrelds, IM; Hoorn, EJ; Huang, S; Kim, JB; Melton, L; Mirabito Colafella, KM; Poglitsch, M; Ren, L; Uijl, E; van Veghel, R; Zlatev, I | 1 |
| Dormiani, K; Homayouni Moghadam, F; Nasr-Esfahani, MH; Poorgolizadeh, E; Rezaei, N | 1 |
| Abraham, I; Alkhatib, N; Brié, H; Denhaerynck, K; Hamarneh, D; MacDonald, K; Vancayzeele, S | 1 |
| Fujiwara, T; Hoshide, S; Kanegae, H; Kario, K; Tomitani, N | 1 |
| Chen, LL; Li, Y; Wang, JG; Xie, JH; Xu, SK; Zeng, WF | 1 |
| Elena Hernandez-Campos, M; Flores-Monroy, J; Lezama-Martinez, D; Martinez-Aguilar, L; Valencia-Hernandez, I | 1 |
| Rakugi, H; Yamamoto, K | 1 |
| Alhan, A; Altay, H; Altın, C; Ataş, AE; Baş, MM; Çakmak, HA; Demirkan, B; Dereli, S; Durakoğlugil, ME; Ekici, B; Fahri Erkan, A; Karavelioğlu, Y; Kılıçaslan, B; Kılıçaslan, F; Kıvrak, T; Küçük, M; Olgun, FE; Özkan, H; Şabanoğlu, C; Tengiz, İ; Yaman, M; Yenerçağ, M; Yiğit, Z; Zoghi, M | 1 |
| Camerotto, A; Cuppini, S; Mazza, A; Minuz, P; Rigatelli, G; Rubello, D; Schiavon, L; Torin, G; Townsend, DM | 1 |
| Anand, IS; Düngen, HD; Jackson, AM; Jhund, PS; Lam, CSP; Lefkowitz, MP; Linssen, G; Lund, LH; Maggioni, AP; McMurray, JJV; Pfeffer, MA; Rouleau, JL; Saito, Y; Saraiva, JFK; Senni, M; Solomon, SD; Vardeny, O; Wijkman, MO; Yilmaz, MB; Zile, MR | 1 |
| Gallo, G; Volpe, M | 1 |
| Alfadda, AA; Alsalman, N; Bazighifan, A; Gul, R | 1 |
| Hafeez, K; Izzo, JL; Jia, Y; Zappe, DH; Zhang, J | 1 |
| Paton, DM | 1 |
| Gervasini, G; Robles, NR | 1 |
| Chrysochoou, C; Georgiopoulos, G; Kalos, T; Kasiakogias, A; Katsiki, N; Konstantinidis, D; Oikonomou, D; Thomopoulos, C; Tousoulis, D; Tsioufis, C | 1 |
| Moon, JS; Won, KC | 1 |
| Ahn, YB; Choi, SH; Han, SJ; Jang, HC; Kim, DJ; Kim, HJ; Kim, HY; Kim, NH; Kim, SH; Kim, TH; Kim, YH; Ko, SH; Lee, KW; Lim, S; Seo, JA; Shin, DH | 1 |
| Cockcroft, JR; Giles, TD; Jakate, A; Pitt, B; Wright, HM | 1 |
| Ayalasomayajula, S; Greeley, M; Hsiao, HL; Kode, K; Langenickel, TH; Pal, P; Petruck, J; Prescott, MF; Rajman, I; Schuehly, U; Sunkara, G; Zhou, W | 1 |
| Chrysant, SG | 5 |
| Doka, G; Klimas, J; Kralova, E; Krenek, P; Potucek, P; Radik, M | 1 |
| Li, N; Ma, R; Yu, H; Yu, J; Zhao, X; Zhao, Y | 1 |
| El-Ashmony, SM; Fatani, SH; Kamel, HF; Shamardl, HA | 1 |
| Grimm, D; Krüger, M; Nielsen, PM; Simonsen, U; Wehland, M | 1 |
| Barbera, V; Bellasi, A; Cozzolino, M; De Pascalis, A; Di Lullo, L; Floccari, F; Mudoni, A; Rivera, R; Ronco, C; Santoro, A; Verdesca, S | 1 |
| Akkermans, R; Biermans, M; Deinum, J; Lenders, JWM; van der Wel, MC; van Weel, C | 1 |
| Blais, C; Guénette, L; Hamel, D; Leclerc, J; Poirier, P; Rochette, L | 1 |
| Hafeez, K; Rakugi, H; Supasyndh, O; Wang, J; Zhang, J; Zhang, Y | 1 |
| Chae, SC; Jeong, MH; Kim, CH; Kim, DS; Lee, HY; Oh, BH; Song, JK | 1 |
| Goto, K; Kansui, Y; Kitazono, T; Matsumura, K; Ohtsubo, T; Seki, T | 1 |
| Ruilope, LM; Ruiz-Hurtado, G | 2 |
| Abdel Kawy, HS | 1 |
| Albrecht, D; Blaak, EE; Engeli, S; Goossens, GH; Haufe, S; Havekes, B; Heise, T; Jax, T; Jordan, J; Langenickel, TH; May, M; Pal, P; Stinkens, R; Tegtbur, U | 1 |
| Accetto, R; Barbic Zagar, B; Sirenko, Y; Vincelj, J; Widimsky, J; Yevgenyevna, IC | 1 |
| Doumas, M; Imprialos, KP; Stavropoulos, K | 1 |
| Fujiwara, T; Kanegae, H; Kario, K; Tomitani, N | 1 |
| Aizenberg, D; Chen, CW; Cheung, DG; Gorbunov, V; Hafeez, K; Zhang, J | 1 |
| Berge, E; Hua, TA; Julius, S; Kjeldsen, SE; Liestøl, K; Mancia, G; Mehlum, MH; Parati, G; Rothwell, PM; Weber, MA | 1 |
| Copenhaver, AM; Lamberton, NH | 1 |
| Choi, MH; Hong, JM; Lee, JS; Lee, SE; Lee, SJ; Park, RW; Yoon, D | 1 |
| Kario, K | 1 |
| Albrecht, D; Blaak, EE; Engeli, S; Goossens, GH; Hartmann, N; Havekes, B; Heise, T; Jax, T; Jocken, JW; Jordan, J; Kaiser, S; Langenickel, TH; Letzkus, M; May, M; Schaper, N; Schindler, C; Stinkens, R; van der Kolk, BW | 1 |
| Goodchild, TT; Koiwaya, H; Lefer, DJ; Li, Z; Polhemus, DJ; Scarborough, A; Trivedi, RK; Yoo, D | 1 |
| Shen, T; Wang, J; Yu, J; Yu, Y | 1 |
| Bianchi, F; Cotugno, M; Forte, M; Madonna, M; Marchitti, S; Rubattu, S; Stanzione, R; Volpe, M | 1 |
| Laurent, S; Mancia, G; Poulter, N | 1 |
| Dai, M; Qian, D; Tao, H; Zhang, C | 1 |
| Ariano, C; De Vecchis, R | 1 |
| Gegeshidze, N; Kapetivadze, V; Lazashvili, T; Maglapheridze, Z; Tabukashvili, R; Tchaava, K | 1 |
| Dong, Z; Li, G; Li, L; Liang, Y; Liu, E; Liu, T; Niu, X; Qi, W; Zhao, Z | 1 |
| Antonio, ZL; Glazer, RD; Kang, HG; Lou-Meda, R; Stiller, B; Tan, M; Valentin, MA; Wang, L; Yap, HK; Zielinska, E | 1 |
| Battise, D; Boland, CL; Nuzum, DS | 1 |
| Presta, V; Tocci, G | 1 |
| Georgianos, PI; Liakopoulos, V; Zebekakis, PE | 1 |
| Atar, D; Kjeldsen, SE; von Lueder, TG | 1 |
| Chen, T; Hu, SY; Jia, JY; Jiang, JQ; Shang, WY; Wei, L; Xu, PC; Yan, TK | 1 |
| Aykan, DA; Eser, N; Koca, TT; Yaman, S | 1 |
| Bhalla, V; Byrd, JB; Chertow, GM | 1 |
| Ariano, C; De Vecchis, R; Soreca, S | 1 |
| Li, N; Ma, R; Yu, J; Yu, X; Zhao, X; Zhao, Y | 1 |
| Balmforth, C; Jhund, PS; Lefkowitz, M; McMurray, JJV; Packer, M; Rizkala, AR; Rouleau, JL; Shen, L; Shi, V; Simpson, J; Solomon, SD; Swedberg, K; Zile, MR | 1 |
| Cho, S; Gwon, MR; Kang, WY; Kim, BK; Lee, HW; Ohk, B; Seong, SJ; Yang, DH; Yoon, YR | 1 |
| Burnier, M; Kjeldsen, SE; Narkiewicz, K; Oparil, S | 1 |
| Guo, Y; Jia, J; Li, L; Li, Q; Lin, S; Liu, Y; Wang, F; Zhang, W | 1 |
| Bagga, A; Coppo, R; Kadwa, M; Schaefer, F; Schlosshauer, R; Senguttuvan, P; Zhang, Y | 1 |
| Freytag, S; Hagendorff, A; Klebs, S; Müller, A | 1 |
| Arslan, E; Ay, SA; Balta, S; Bozoglu, E; Bulucu, F; Cakar, M; Celik, T; Demirbas, S; Demirkol, S; Karaman, M; Kurt, O; Naharci, MI | 1 |
| Abraham, I; Bowles, J; Brié, H; Hermans, C; Lee, C; Macdonald, K; Piotrowski, K; Vancayzeele, S | 1 |
| Amano, T; Harada, K; Ichimiya, S; Ishii, H; Kanashiro, M; Kobayashi, M; Kurebayashi, N; Marui, N; Murohara, T; Sone, T; Suzuki, S; Tsuboi, H; Uetani, T; Yoshikawa, D | 1 |
| Aksenova, AV; Chazova, IE; Elfimova, EM; Galitsin, PV; Litvin, AY; Rogoza, AN; Sukmarova, ZN | 1 |
| Eckert, S; Freytag, SB; Klebs, SH; Müller, A | 1 |
| Calhoun, DA; Crikelair, N; Glazer, RD; Jia, Y; Lacourcière, Y | 1 |
| Anisiuba, BC; Ba, SA; Boombhi, HJ; Ezeala-Adikaibe, B; Ijoma, CK; Jacobs, L; Kaptue, J; Kingue, S; Kolo, PM; Lemogoum, D; M'Buyamba-Kabangu, JR; Mipinda, JB; Ndiaye, MB; Odili, A; Omotoso, BA; Osakwe, CE; Staessen, JA; Thijs, L; Ulasi, II | 1 |
| Ruilope, LM; Sierra, C | 1 |
| Alajbegovic, A; Alajbegovic, L; Alajbegovic, S; Ambeskovic, M; Deljo, D; Sukalo, A; Vranic, JD | 1 |
| D'Angelo, A; Derosa, G; Fogari, R; Gualtierotti, R; Mugellini, A; Zoppi, A | 1 |
| Berktaş, M; Boyacı, B; Kızılırmak, P; Yalçın, MR | 1 |
| Gnudi, L; Hill, B; Karalliedde, J; Maltese, G; Viberti, G | 1 |
| Chae, SC; Jeong, MH; Kim, DS; Kim, KS; Lee, H; Oh, BH | 1 |
| Anyfanti, P; Douma, S; Doumas, M; Ferro, A; Garypidou, V; Gavriilaki, E; Gkaliagkousi, E; Markala, D; Papadopoulos, N; Petidis, K; Triantafyllou, A; Yiannaki, E | 1 |
| Kami, M; Shibuya, K; Tanimoto, T | 1 |
| Brown, A; Burrell, LM; Carrington, MJ; Jennings, GL; Kurstjens, NP; Nelson, M; Stewart, S; Stocks, NP; Swemmer, CH | 1 |
| Abraham, I; Aerts, A; Brié, H; Denhaerynck, K; Hermans, C; MacDonald, K; Sun, D; Van Camp, Y; Vancayzeele, S; Villa, L | 1 |
| Kondo, T; Maeda, K; Matsushita, K; Muramatsu, T; Murohara, T; Nagahiro, T; Shintani, S; Yamashita, K | 1 |
| Barreira, JC; Iotti, A; Laborde, HA; Rivero, MA; Zazzetti, F | 1 |
| Allen, RR; Ghushchyan, V; Kaila, S; Nair, KV; Saseen, JJ | 1 |
| Akasaka, H; Miura, T; Saitoh, S; Shimamoto, K; Yoshida, H | 1 |
| Asai, S; Kanou, N; Nakayama, T; Nishida, Y; Susa, N; Takahashi, Y | 1 |
| Coakley, C; Hough, A; Parra, D; Shah, S | 2 |
| Achouba, A; Beaussier, H; Boutouyrie, P; Laurent, S | 1 |
| Huang, QF; Li, Y; Wang, JG | 1 |
| Baek, SH; Chiang, FT; Gotou, H; Inubushi-Molessa, A; Kario, K; Lefkowitz, M; Sun, N; Supasyndh, O; Zhang, J; Zhang, Y | 1 |
| Donova, T; Koshtikova, K; Manov, E; Naidenov, S; Rangelov, Y; Runev, N; Shabani, R; Vitlyanova, K | 1 |
| Brunel, P; Cardenas, P; Cockcroft, JR; Hester, A; Kario, K; Williams, B; Zappe, DH; Zhang, J | 1 |
| Caffrey, JL; Chang, CH; Lai, MS; Lin, JW; Wu, LC | 1 |
| Aydoğdu, A; Azal, Ö; Baysan, O; Deniz, F; Meriç, C; Sağlam, K; Serdar, M; Taşçı, İ | 1 |
| Batman, A; Can, B; Celebi, A; Hulagu, S; Korkmaz, U; Sali, M; Senturk, O; Yilmaz, H | 1 |
| Burrell, LM; Carrington, MJ; de Looze, FJ; Esterman, A; Harris, M; Hung, J; Jennings, GL; Kurstjens, NP; Stewart, S; Stocks, NP; Swemmer, CH | 1 |
| Georgianos, PI; Sarafidis, PA; Zebekakis, PE | 1 |
| Douma, S; Gavriilaki, E; Gkaliagkousi, E; Nikolaidou, B; Triantafyllou, G | 1 |
| Feihl, F; Waeber, B | 2 |
| Basile, J; Bharucha, DB; Chen, W; Giles, TD; Gradman, AH; Pattathil, M; Weber, MA | 1 |
| Ar, I; Ilerigelen, B; Kızılırmak, P | 1 |
| Ha, JW; Jung, HO; Park, JB; Rhee, MY | 1 |
| Sakaida, H; Sano, T; Suzuki, H; Taki, W; Toma, N; Umeda, Y; Yamamoto, A | 1 |
| Hasegawa, Y; Katayama, T; Kim-Mitsuyama, S; Koibuchi, N; Ma, M; Maeda, M; Nakagawa, T; Ogawa, H; Sueta, D; Toyama, K; Uekawa, K; Waki, H | 1 |
| Amiya, E; Hirata, Y; Hosoya, Y; Kawarasaki, S; Nagai, R; Nakao, T; Omori, K; Ozeki, A; Tahara, Y; Takata, M; Watanabe, A; Watanabe, M; Watanabe, S; Yamada, N | 1 |
| Bae, JH; Ihm, SH; Jeon, DW; Joo, SJ; Jung, BC; Jung, IH; Kang, SM; Lee, NH; Park, SM; Park, TH; Park, WJ; Pyun, WB; Shin, ES; Shin, JH; Song, JM; Sung, KC; Yoon, YW; Youn, JC | 1 |
| Kartashova, EA; Romantsov, MG; Sarvilina, IV | 1 |
| Izumikawa, Y; Kato, H; Kojima, K; Kubo, E; Nagura, M; Nosaka, H; Shima, T; Shimada, M; Shiraishi, T; Tanemoto, M; Tomioka, S; Uchida, S; Ueda, S; Yano, H | 1 |
| Baigent, C; Haynes, R; Judge, P; Landray, MJ | 1 |
| Kobalava, ZhD; Kotovskaia, IuV; Kravtsova, OA; Lobzhanidze, TV | 1 |
| Harada, E; Hattori, T; Matsuura, N; Murohara, T; Nagasawa, K; Nagata, K; Niinuma, K; Takahashi, K; Takatsu, M; Watanabe, S | 1 |
| Crikelair, N; Kandra, A; Palatini, P; Zappe, DH | 1 |
| Greenwood, JP; Negrou, K; Oliver, JJ; Plein, S; Ripley, DP; Struthers, AD; Worthy, G | 1 |
| Miller, R; Solomon, SD; Vardeny, O | 1 |
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| Duprez, D; Ferdinand, K; Purkayastha, D; Samuel, R; Wright, R | 1 |
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| Ofili, EO; Purkayastha, D; Samuel, R; Sowers, JR; Zappe, DH | 1 |
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| Cushman, WC; Duprez, DA; Izzo, JL; Purkayastha, D; Samuel, R; Weintraub, HS; Zappe, DH | 1 |
| Koide, M; Matsubara, H; Sawada, T; Shiraishi, J; Yamada, H | 1 |
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| Derosa, G; Fogari, R; Maffioli, P; Mugellini, A; Perrone, T; Preti, P; Zoppi, A | 1 |
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| Sun, CX; Tao, CW; Wu, ZB; Yu, QG; Zhang, Y | 1 |
| Fan, J; Hoffman, MR; Qin, Y; Ren, H; Xu, G; Zhang, M | 1 |
| Derosa, G; Fogari, R; Maffioli, P; Mugellini, A; Preti, P; Zoppi, A | 1 |
| Alessi, T; Giles, TD; Purkayastha, D; Zappe, D | 1 |
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| Deedwania, PC; Egan, BM; Purkayastha, D; Samuel, R; Sowers, JR; Zappe, DH | 1 |
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| deBlois, D; Der Sarkissian, S; Duguay, D; Hamet, P; Marchand, EL | 1 |
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| Handrock, R; Schmieder, RE | 1 |
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| Brunner, H; Ekman, S; Hansson, L; Julius, S; Kjeldsen, SE; Laragh, JH; McInnes, G; Platt, F; Schork, AM; Smith, B; Weber, M; Zanchetti, A | 1 |
| Buganov, AA; Mamedova, SI; Novokrestova, SV; Salamatina, LV; Shesterikova, NV; Umanskaia, EL | 1 |
| Abe, Y; Fukui, T; Hitomi, H; Kimura, S; Kiyomoto, H; Kobori, H; Kohno, M; Nishiyama, A; Rahman, M; Shokoji, T; Yao, L; Zhang, GX | 1 |
| Ayala, DE; Calvo, C; Covelo, M; Domínguez, MJ; Fernández, JR; Hermida, RC; López, JE; Mojón, A | 1 |
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| Delles, C; Handrock, R; Klingbeil, AU; Schmieder, RE; Schneider, MP; Weidinger, G | 1 |
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| Corradi, L; Fogari, R; Mugellini, A; Pasotti, C; Preti, P; Rinaldi, A; Zoppi, A | 1 |
| Fogari, R; Marasi, G; Mugellini, A; Pasotti, C; Poletti, L; Preti, P; Rinaldi, A; Zoppi, A | 1 |
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| Ambrosia, GB; Caiazza, A; Malacco, E; Mugellini, A; Palatini, P; Santonastaso, M; Spagnuolo, V | 1 |
| Ayala, DE; Calvo, C; Hermida, RC; Ruilope, LM | 1 |
| Isaka, N; Ito, M; Kaibuchi, K; Kongo, M; Kureishi, Y; Moriki, N; Nakakuki, T; Nakano, T; Okamoto, R; Seko, T | 1 |
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| Brunner, HR; Ekman, S; Hansson, L; Hua, T; Julius, S; Kjeldsen, SE; Laragh, J; McInnes, GT; Mitchell, L; Plat, F; Schork, A; Smith, B; Weber, M; Zanchetti, A | 1 |
| Brunner, HR; Ekman, S; Hansson, L; Hua, T; Julius, S; Kjeldsen, SE; Laragh, JH; McInnes, GT; Mitchell, L; Plat, F; Schork, MA; Smith, B; Weber, MA; Zanchetti, A | 1 |
| Epstein, M; Hollenberg, NK | 1 |
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| Bertocchi, F; Gargiulo, A; Malacco, E; Palatini, P; Santonastaso, M; Spagnuolo, V; Varì, NA | 1 |
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138 review(s) available for valsartan and Hypertension
| Article | Year |
|---|---|
Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Growth Hormone; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Models, Molecular; Receptor, Angiotensin, Type 1; Tetrazoles; Thiophenes; Thromboxane A2 | 2003 |
Dyskalemia risk associated with fixed-dose anti-hypertensive medication combinations.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Drug Combinations; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hyperkalemia; Hypertension; Hypokalemia; Tetrazoles; Valsartan | 2022 |
Newer Drugs to Reduce High Blood Pressure and Mitigate Hypertensive Target Organ Damage.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Combinations; Female; Heart Failure; Humans; Hypertension; Male; Stroke Volume; Tetrazoles; Valsartan; Ventricular Function, Left | 2022 |
Angiotensin receptor-neprilysin inhibitors for hypertension-hemodynamic effects and relevance to hypertensive heart disease.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Drug Combinations; Heart Failure; Hemodynamics; Humans; Hypertension; Neprilysin; Receptors, Angiotensin; Tetrazoles; Valsartan | 2022 |
Efficacy and safety of sacubitril/valsartan in the treatment of middle-aged and elderly patients with hypertension: a systematic review and meta-analysis of randomized controlled trials.
Topics: Aged; Aminobutyrates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Humans; Hypertension; Middle Aged; Randomized Controlled Trials as Topic; Tetrazoles; Valsartan | 2022 |
Sacubitril-valsartan for the treatment of hypertension in China: A cost-utility analysis based on meta-analysis of randomized controlled trials.
Topics: Aminobutyrates; Antihypertensive Agents; Biphenyl Compounds; Cost-Benefit Analysis; Heart Failure; Humans; Hypertension; Male; Middle Aged; Randomized Controlled Trials as Topic; Valsartan | 2022 |
Novel antihypertensive agents for resistant hypertension: what does the future hold?
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Drug Combinations; Hypertension; Neprilysin; Tetrazoles; Valsartan | 2022 |
Network meta-analysis of sacubitril/valsartan for the treatment of essential hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Drug Combinations; Essential Hypertension; Humans; Hypertension; Network Meta-Analysis; Randomized Controlled Trials as Topic; Tetrazoles; Valsartan | 2023 |
Different Doses of Sacubitril/Valsartan Compared with Olmesartan in Patients with Essential Hypertension: A Systematic Review and Meta-Analysis.
Topics: Aminobutyrates; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Blood Pressure; Drug Combinations; Essential Hypertension; Humans; Hypertension; Tetrazoles; Valsartan | 2023 |
Efficacy of single-pill combination in uncontrolled essential hypertension: A systematic review and network meta-analysis.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Essential Hypertension; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Losartan; Network Meta-Analysis; Telmisartan; Tetrazoles; Valine; Valsartan | 2023 |
Emerging Drug Classes and Their Potential Use in Hypertension.
Topics: Aminobutyrates; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Drug Approval; Drug Combinations; Drug Delivery Systems; Drugs, Investigational; Female; Forecasting; Humans; Hypertension; Male; Neprilysin; Patient Safety; Tetrazoles; Valsartan | 2019 |
An evaluation of the fixed-dose combination sacubitril/valsartan for the treatment of arterial hypertension.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Drug Combinations; Humans; Hypertension; Molecular Structure; Tetrazoles; Valsartan | 2020 |
Effects of LCZ696 (Sacubitril/Valsartan) on Blood Pressure in Patients with Hypertension: A Meta-Analysis of Randomized Controlled Trials.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Humans; Hypertension; Randomized Controlled Trials as Topic; Valsartan | 2020 |
Nebivolol/valsartan combination for the treatment of hypertension: a review.
Topics: Antihypertensive Agents; Blood Pressure; Drug Combinations; Humans; Hypertension; Nebivolol; Valsartan | 2021 |
Plasma Trough Concentrations of Antihypertensive Drugs for the Assessment of Treatment Adherence: A Meta-Analysis.
Topics: Amlodipine; Antihypertensive Agents; Humans; Hydrochlorothiazide; Hypertension; Treatment Adherence and Compliance; Valsartan | 2021 |
Do neprilysin inhibitors walk the line? Heart ameliorative but brain threatening!
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Brain Diseases; Chemotherapy-Related Cognitive Impairment; Drug Combinations; Heart Failure; Humans; Hypertension; Neprilysin; Valsartan | 2021 |
Angiotensin receptor-neprilysin inhibitors: Comprehensive review and implications in hypertension treatment.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Drug Combinations; Heart Failure; Humans; Hypertension; Neprilysin; Receptors, Angiotensin; Stroke Volume; Tetrazoles; Valsartan | 2021 |
Nebivolol/valsartan: Fixed-dose combination for treatment of hypertension.
Topics: Adrenergic beta-1 Receptor Agonists; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Drug Approval; Drug Combinations; Humans; Hypertension; Nebivolol; Treatment Outcome; United States; United States Food and Drug Administration; Valsartan; Vasodilator Agents | 2017 |
Potential beneficial effects of sacubitril-valsartan in renal disease: a new field for a new drug.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cardiovascular Diseases; Drug Combinations; Heart Failure; Humans; Hypertension; Kidney Diseases; Renin-Angiotensin System; Tetrazoles; Valsartan | 2017 |
Hypertension and Heart Failure with Preserved Ejection Fraction: Connecting the Dots.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Drug Combinations; Heart Failure; Humans; Hypertension; Life Style; Prognosis; Risk Factors; Stroke Volume; Sympathectomy; Tetrazoles; Valsartan | 2017 |
Rationale for nebivolol/valsartan combination for hypertension: review of preclinical and clinical data.
Topics: Antihypertensive Agents; Drug Therapy, Combination; Humans; Hypertension; Nebivolol; Randomized Controlled Trials as Topic; Valsartan | 2017 |
Pharmacokinetic, pharmacodynamic, and antihypertensive effects of the neprilysin inhibitor LCZ-696: sacubitril/valsartan.
Topics: Aminobutyrates; Angioedema; Angiotensin Receptor Antagonists; Antihypertensive Agents; Atrial Natriuretic Factor; Biphenyl Compounds; Clinical Trials as Topic; Cough; Cyclic GMP; Diuresis; Drug Combinations; Heart Failure; Heart Ventricles; Humans; Hypertension; Natriuretic Peptide, Brain; Neprilysin; Peptide Fragments; Renin-Angiotensin System; Stroke Volume; Tetrazoles; Valsartan; Vasodilation | 2017 |
The Effects of LCZ696 in Patients With Hypertension Compared With Angiotensin Receptor Blockers: A Meta-Analysis of Randomized Controlled Trials.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Humans; Hypertension; Tetrazoles; Valsartan | 2017 |
The Combination of Valsartan and Sacubitril in the Treatment of Hypertension and Heart Failure - an Update.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Heart Failure; Humans; Hypertension; Imidazoles; Natriuretic Peptides; Neprilysin; Renin-Angiotensin System; Tetrazoles; Treatment Outcome; Valsartan | 2018 |
[Neprilysin inhibition and chronic kidney disease].
Topics: Aminobutyrates; Angioedema; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Cardiovascular Diseases; Clinical Trials as Topic; Disease Progression; Diuresis; Drug Combinations; Heart Failure; Humans; Hypertension; Kidney Failure, Chronic; Models, Biological; Molecular Targeted Therapy; Natriuresis; Natriuretic Peptides; Neprilysin; Proteinuria; Renal Insufficiency, Chronic; Renin-Angiotensin System; Tetrazoles; Valsartan | 2017 |
The Sacubitril/Valsartan, a First-in-Class, Angiotensin Receptor Neprilysin Inhibitor (ARNI): Potential Uses in Hypertension, Heart Failure, and Beyond.
Topics: Aged; Aging; Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Drug Combinations; Heart Failure; Humans; Hypertension; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Stroke Volume; Systole; Tetrazoles; Treatment Outcome; Valsartan | 2018 |
Nebivolol/Valsartan: A Novel Antihypertensive Fixed-Dose Combination Tablet.
Topics: Antihypertensive Agents; Blood Pressure; Clinical Trials, Phase III as Topic; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Nebivolol; Randomized Controlled Trials as Topic; Renin; Tablets; Treatment Outcome; Valsartan | 2019 |
Antihypertensive effect of sacubitril/valsartan: a meta-analysis.
Topics: Aged; Aged, 80 and over; Aminobutyrates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Drug Combinations; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Valsartan | 2019 |
Effect and safety of LCZ696 in the treatment of hypertension: A meta-analysis of 9 RCT studies.
Topics: Aminobutyrates; Antihypertensive Agents; Biphenyl Compounds; Drug Combinations; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Valsartan | 2019 |
Meta-analysis of three observational studies of amlodipine/valsartan in hypertensive patients with additional risk factors.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Male; Obesity, Abdominal; Risk Factors; Tetrazoles; Valine; Valsartan | 2013 |
Overview of clinical use and side effect profile of valsartan in Chinese hypertensive patients.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; China; Drug Therapy, Combination; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2013 |
Neprilysin inhibition in chronic kidney disease.
Topics: Aminobutyrates; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Cardiovascular Diseases; Clinical Trials as Topic; Disease Progression; Drug Combinations; Heart Failure; Humans; Hypertension; Kidney Failure, Chronic; Natriuresis; Nephrology; Neprilysin; Proteinuria; Pyridines; Renin-Angiotensin System; Tetrazoles; Thiazepines; Treatment Outcome; Valsartan | 2015 |
Combined neprilysin and renin-angiotensin system inhibition for the treatment of heart failure.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biomarkers; Biphenyl Compounds; Clinical Trials as Topic; Drug Combinations; Drug Therapy, Combination; Heart Failure; Humans; Hypertension; Natriuretic Peptide, Brain; Neprilysin; Peptide Fragments; Renin-Angiotensin System; Tetrazoles; Valsartan | 2014 |
Hypertension and valsartan.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Drug Combinations; Humans; Hypertension; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2014 |
Nebivolol and valsartan as a fixed-dose combination for the treatment of hypertension.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-3 Receptor Agonists; Angiotensin II Type 1 Receptor Blockers; Animals; Benzopyrans; Blood Pressure; Drug Combinations; Ethanolamines; Humans; Hypertension; Nebivolol; Tetrazoles; Valine; Valsartan | 2015 |
LCZ696: the next step in improving RAS inhibition?
Topics: Aminobutyrates; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Drug Combinations; Heart Failure; Humans; Hypertension; ras Proteins; Renin-Angiotensin System; Tetrazoles; Valsartan | 2015 |
Angiotensin receptor-neprilysin inhibitors: clinical potential in heart failure and beyond.
Topics: Aminobutyrates; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Clinical Trials as Topic; Drug Combinations; Heart Failure; Humans; Hypertension; Indans; Natriuretic Peptide, Brain; Neprilysin; Propionates; Pyridines; Receptors, Angiotensin; Renin-Angiotensin System; Risk Factors; Stroke Volume; Tetrazoles; Thiazepines; Valsartan | 2015 |
Angiotensin II Receptor Blocker Neprilysin Inhibitor (ARNI): New Avenues in Cardiovascular Therapy.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Drug Combinations; Drug Discovery; Heart Failure; Humans; Hypertension; Neprilysin; Stroke Volume; Tetrazoles; Valsartan | 2015 |
LCZ696 (Valsartan/Sacubitril)--A Possible New Treatment for Hypertension and Heart Failure.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Drug Combinations; Heart Failure; Humans; Hypertension; Molecular Structure; Natriuretic Peptides; Neprilysin; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Tetrazoles; Treatment Outcome; Valsartan | 2016 |
The two faces of hypertension: role of aortic stiffness.
Topics: Aging; Aminobutyrates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aorta; Arteriosclerosis; Biphenyl Compounds; Blood Pressure; Diastole; Drug Combinations; Humans; Hypertension; Microcirculation; Prevalence; Pulse Wave Analysis; Pyridines; Risk Factors; Systole; Tetrazoles; Thiazepines; Valsartan; Vascular Resistance; Vascular Stiffness | 2016 |
Combined Angiotensin Receptor Antagonism and Neprilysin Inhibition.
Topics: Abnormalities, Drug-Induced; Aminobutyrates; Angioedema; Angiotensin Receptor Antagonists; Biphenyl Compounds; Bradykinin; Contraindications; Drug Combinations; Drug Costs; Drug Synergism; Enalapril; Enzyme Inhibitors; Female; Follow-Up Studies; Heart Failure; Humans; Hyperkalemia; Hypertension; Kidney; Multicenter Studies as Topic; Natriuretic Peptides; Neprilysin; Pregnancy; Prodrugs; Prospective Studies; Pyridines; Randomized Controlled Trials as Topic; Stroke Volume; Tetrazoles; Thiazepines; Valsartan | 2016 |
Fixed-dose combination therapy of nebivolol and valsartan for the treatment of hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Drug Combinations; Humans; Hypertension; Nebivolol; Renin-Angiotensin System; Valsartan | 2016 |
Vascular ageing and interventions: lessons and learnings.
Topics: Aging; Aminobutyrates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteriosclerosis; Biphenyl Compounds; Blood Pressure; Drug Combinations; Humans; Hypertension; Tetrazoles; Valsartan; Vascular Stiffness | 2016 |
Angiotensin receptor neprilysin inhibitor LCZ696: a novel targeted therapy for arterial hypertension?
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure; Drug Combinations; Humans; Hypertension; Neprilysin; Tetrazoles; Treatment Outcome; Valsartan | 2015 |
Focus on the Novel Cardiovascular Drug LZC696: from Evidence to Clinical Consideration.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cardiovascular Agents; Contraindications; Cost-Benefit Analysis; Drug Combinations; Heart Failure; Humans; Hypertension; Myocardial Infarction; Renal Insufficiency, Chronic; Tetrazoles; Valsartan | 2016 |
Novel Drugs for Hypertension and Heart Failure: Struggling for a Place Under the Sun.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Drug Combinations; Heart Failure; Humans; Hypertension; Mineralocorticoid Receptor Antagonists; Naphthyridines; Neprilysin; Tetrazoles; Valsartan | 2017 |
Antihypertensive efficacy of olmesartan medoxomil or valsartan in combination with amlodipine: a review of factorial-design studies.
Topics: Amlodipine; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Olmesartan Medoxomil; Placebos; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2009 |
Valsartan vs. other angiotensin II receptor blockers in the treatment of hypertension: a meta-analytical approach.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Dose-Response Relationship, Drug; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Middle Aged; Prospective Studies; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Single-pill combination of amlodipine and valsartan in the management of hypertension.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Combinations; Humans; Hypertension; Patient Compliance; Tetrazoles; Valine; Valsartan | 2009 |
Valsartan/hydrochlorothiazide: pharmacology and clinical efficacy.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Valine; Valsartan | 2009 |
Amlodipine/valsartan single-pill combination: a review of its use in the management of hypertension.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Drug Combinations; Drug Interactions; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2009 |
Renal protective effect of RAAS blockade across the renal continuum, with a review of the efficacy and safety of valsartan.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cytoprotection; Humans; Hypertension; Hypertension, Renal; Kidney; Kidney Failure, Chronic; Models, Biological; Renin-Angiotensin System; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Valsartan: more than a decade of experience.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; C-Reactive Protein; Cardiovascular Diseases; Child; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Hypotension; Meta-Analysis as Topic; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan | 2009 |
Angiotensin II type 1 receptor blockade: high hopes sent back to reality?
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Consensus; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Follow-Up Studies; Heart Failure; Hospitalization; Humans; Hypertension; Hypertrophy, Left Ventricular; Middle Aged; Practice Guidelines as Topic; Primary Prevention; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Risk Factors; Saralasin; Secondary Prevention; Stroke; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2009 |
Valsartan plus hydrochlorothiazide for first-line therapy in hypertension.
Topics: Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Patient Compliance; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2009 |
Aliskiren/valsartan (Valturna) for hypertension.
Topics: Amides; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Drug Combinations; Drug Interactions; Fumarates; Humans; Hypertension; Randomized Controlled Trials as Topic; Renin; Tetrazoles; Valine; Valsartan | 2009 |
The antihypertensive effectiveness and safety of dual RAAS blockade with aliskiren and valsartan.
Topics: Amides; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Drug Interactions; Drug Therapy, Combination; Fumarates; Humans; Hypertension; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2010 |
Combination therapy for managing difficult-to-treat patients with stage 2 hypertension: focus on valsartan-based combinations.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Black or African American; Calcium Channel Blockers; Diuretics; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Obesity; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2011 |
A systematic review and meta-analysis of telmisartan versus valsartan in the management of essential hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Confidence Intervals; Diastole; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Renin-Angiotensin System; Risk; Systole; Telmisartan; Tetrazoles; Valine; Valsartan | 2010 |
Valsartan-induced angioedema in a patient on angiotensin-converting enzyme inhibitor for years: case report and literature review.
Topics: Aged, 80 and over; Angioedema; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Female; Humans; Hypertension; Tetrazoles; Time Factors; Valine; Valsartan | 2012 |
Aliskiren and valsartan combination therapy for the management of hypertension.
Topics: Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Fumarates; Humans; Hypertension; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2010 |
Dual-acting angiotensin receptor-neprilysin inhibition.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Volume; Endopeptidases; Heart Failure; Humans; Hypertension; Neprilysin; Receptor, Angiotensin, Type 1; Tetrazoles; Valine; Valsartan; Vasoconstriction | 2011 |
Valsartan-amlodipine-hydrochlorothiazide: the definitive fixed combination?
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Medication Adherence; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
A drug safety evaluation of valsartan.
Topics: Age Factors; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Child; Drug Therapy, Combination; Humans; Hypertension; Risk Factors; Tetrazoles; Valine; Valsartan | 2011 |
Valsartan use in pediatric hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Child; Humans; Hypertension; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
Real-world effectiveness of valsartan on hypertension and total cardiovascular risk: review and implications of a translational research program.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Hypertension; Program Evaluation; Risk Assessment; Risk Factors; Tetrazoles; Translational Research, Biomedical; Treatment Outcome; Valine; Valsartan | 2011 |
Combination delapril/manidipine as antihypertensive therapy in high-risk patients.
Topics: Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Clinical Trials as Topic; Diabetes Complications; Dihydropyridines; Drug Combinations; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Indans; Irbesartan; Losartan; Nitrobenzenes; Obesity; Olmesartan Medoxomil; Piperazines; Ramipril; Tetrazoles; Valine; Valsartan | 2011 |
Update on pathophysiology and treatment of hypertension in the elderly.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Antihypertensive Agents; Blood Pressure; Geriatric Assessment; Humans; Hypertension; Prevalence; Risk Factors; Tetrazoles; United States; Valine; Valsartan | 2011 |
Valsartan plus hydrochlorothiazide: a review of its use since its introduction.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Diuretics; Drug Combinations; Drug Costs; Drug Synergism; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Renal Insufficiency; Tetrazoles; Valine; Valsartan; Ventricular Dysfunction, Left | 2011 |
[Hypertension, obesity, erectile dysfunction. What kind of drug to choose].
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Erectile Dysfunction; Humans; Hypertension; Male; Obesity; Renin-Angiotensin System; Risk Factors; Tetrazoles; Valine; Valsartan | 2011 |
[Application of AT1-angiotensin II receptor blocker valsartan in clinical practice].
Topics: Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Drug Monitoring; Heart Failure; Humans; Hypertension; Randomized Controlled Trials as Topic; Receptors, Angiotensin; Renal Insufficiency; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan; Water-Electrolyte Balance | 2011 |
Single-pill triple-combination therapy: an alternative to multiple-drug treatment of hypertension.
Topics: Amides; Amlodipine; Antihypertensive Agents; Drug Combinations; Drug Design; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Olmesartan Medoxomil; Practice Guidelines as Topic; Practice Patterns, Physicians'; Tetrazoles; Valine; Valsartan | 2011 |
[Medical and social implications of sexual dysfunction and safety of antihypertensive therapy in hypertensive patients].
Topics: Adult; Aged; Androgens; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Erectile Dysfunction; Female; Humans; Hypertension; Male; Middle Aged; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
Hypertension therapy and cardiovascular protection. Effects of angiotensin II receptor block with Valsartan.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Cardiovascular Diseases; Drug Therapy, Combination; Humans; Hypertension; Patient Compliance; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2011 |
[Recent advance in kidney and hypertension research].
Topics: Albuminuria; Amides; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Agonists; Catheter Ablation; Cerebrovascular Circulation; Chronic Disease; Diabetic Nephropathies; Drug Therapy, Combination; Evidence-Based Medicine; Fumarates; Humans; Hypertension; Imidazoles; Kidney; Kidney Diseases; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2012 |
Blood pressure control with angiotensin receptor blocker-based three-drug combinations: key trials.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Olmesartan Medoxomil; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2012 |
Telmisartan or valsartan alone or in combination with hydrochlorothiazide: a review.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Randomized Controlled Trials as Topic; Telmisartan; Tetrazoles; Valine; Valsartan | 2013 |
The pharmacokinetics and pharmacodynamics of valsartan in the post-myocardial infarction population.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Dose-Response Relationship, Drug; Drug Evaluation; Humans; Hypertension; Myocardial Infarction; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Valine; Valsartan | 2012 |
Preventing cardiovascular events with angiotensin II receptor blockers: a closer look at telmisartan and valsartan.
Topics: Angiotensin II Type 2 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Evidence-Based Medicine; Humans; Hypertension; Telmisartan; Tetrazoles; Valine; Valsartan | 2012 |
Effects of telmisartan therapy on interleukin-6 and tumor necrosis factor-alpha levels: a meta-analysis of randomized controlled trials.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Pressure; Calcium Channel Blockers; Confidence Intervals; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Hypertension, Renal; Imidazoles; Interleukin-6; Obesity; Prospective Studies; Publication Bias; Randomized Controlled Trials as Topic; Stents; Telmisartan; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan | 2013 |
A meta-analysis of randomized trials of telmisartan vs. valsartan therapy for blood pressure reduction.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Publication Bias; Randomized Controlled Trials as Topic; Telmisartan; Tetrazoles; Valine; Valsartan | 2013 |
Valsartan/hydrochlorothiazide: a review of its pharmacology, therapeutic efficacy and place in the management of hypertension.
Topics: Antihypertensive Agents; Databases, Bibliographic; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2002 |
Role of valsartan and other angiotensin receptor blocking agents in the management of cardiovascular disease.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cardiac Output, Low; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus; Humans; Hypertension; Hypertrophy, Left Ventricular; Kidney Failure, Chronic; Myocardial Infarction; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2002 |
The relationships between dose and antihypertensive effect of four AT1-receptor blockers. Differences in potency and efficacy.
Topics: Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Irbesartan; Losartan; Male; Randomized Controlled Trials as Topic; Receptor, Angiotensin, Type 1; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2002 |
[Diurnal blood pressure control in the optimal treatment of hypertension].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Circadian Rhythm; Humans; Hypertension; Irbesartan; Losartan; Telmisartan; Tetrazoles; Valine; Valsartan | 2003 |
[Angiotensin I receptor antagonist losartan. Part II. Effects in arterial hypertension and diabetic nephropathy].
Topics: Angiotensin I; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diastole; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Losartan; Meta-Analysis as Topic; Placebos; Prognosis; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors; Systole; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2003 |
[Angiotensin receptor blockers in chronic heart failure].
Topics: Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Double-Blind Method; Heart Failure; Humans; Hypertension; Japan; Losartan; Myocardial Infarction; Neurotransmitter Agents; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Valine; Valsartan; Ventricular Dysfunction, Left; Ventricular Remodeling | 2003 |
[Cardiologic and diabetologic aspects of therapy with angiotensin receptor blocking agents].
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Clinical Trials as Topic; Diabetes Complications; Heart Failure; Humans; Hypertension; Losartan; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2003 |
[Candesartan - a novel AT(1)-angiotensin receptor blocker: peculiarities of pharmacology and experience of use in arterial hypertension].
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diabetic Nephropathies; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Tetrazoles; Thiophenes; Valine; Valsartan | 2004 |
Fixed combination therapy of hypertension: focus on valsartan/hydrochlorothiazide combination (Diovan/HCT).
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan | 2003 |
Assessment of the optimal daily dose of valsartan in patients with hypertension, heart failure, or both.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Dose-Response Relationship, Drug; Heart Failure; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2004 |
VALUE: to the heart of the matter.
Topics: Antihypertensive Agents; Heart Failure; Humans; Hypertension; Risk Factors; Tetrazoles; Valine; Valsartan | 2004 |
VALUE and supremacy of blood pressure control for cardiovascular protection.
Topics: Antihypertensive Agents; Humans; Hypertension; Myocardial Infarction; Stroke; Tetrazoles; Valine; Valsartan | 2004 |
Olmesartan compared with other angiotensin II receptor antagonists: head-to-head trials.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Olmesartan Medoxomil; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
Clinical experience with angiotensin receptor blockers with particular reference to valsartan.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Cardiovascular Diseases; Drug Interactions; Drug Therapy, Combination; Humans; Hypertension; Tetrazoles; Valine; Valsartan | 2004 |
Fetal toxicity of valsartan and possible reversible adverse side effects.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Female; Humans; Hypertension; Kidney; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Tetrazoles; Ultrasonography; Valine; Valsartan | 2004 |
The VALUE trial: a commentary.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Drug Administration Schedule; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
Fetal toxic effects of angiotensin II receptor antagonists: case report and follow-up after birth.
Topics: Amniotic Fluid; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; beta 2-Microglobulin; Child, Preschool; Female; Follow-Up Studies; Gestational Age; Humans; Hypertension; Infant; Infant, Newborn; Male; Pregnancy; Pregnancy Complications, Cardiovascular; Prenatal Exposure Delayed Effects; Renal Insufficiency; Tetrazoles; Valine; Valsartan | 2005 |
Hope in Life and Value of blood pressure control.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Cardiovascular Diseases; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2004 |
valsartan in elderly isolated systolic hypertension (VALISH) study: rationale and design.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Incidence; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2004 |
Update on the efficacy of angiotensin receptor blockers in treatment of hypertension.
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Captopril; Diabetes Complications; Drug Evaluation; Humans; Hypertension; Losartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
The angiotensin receptor antagonist valsartan: a review of the literature with a focus on clinical trials.
Topics: Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Diabetes Mellitus; Drug Administration Schedule; Heart Failure; Humans; Hypertension; Myocardial Infarction; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2006 |
Therapeutic potential of angiotensin receptor blockers in hypertension.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Coronary Disease; Female; Humans; Hypertension; Losartan; Male; Meta-Analysis as Topic; Myocardial Infarction; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Survival Analysis; Tetrazoles; Valine; Valsartan | 2006 |
[VALUE].
Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Double-Blind Method; Endpoint Determination; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Randomized Controlled Trials as Topic; Risk; Tetrazoles; Valine; Valsartan | 2006 |
[VALISH].
Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Cardiovascular Diseases; Clinical Trials as Topic; Endpoint Determination; Evidence-Based Medicine; Humans; Hypertension; Japan; Prospective Studies; Systole; Tetrazoles; Valine; Valsartan | 2006 |
Valsartan/hydrochlorothiazide: a review of its use in the management of hypertension.
Topics: Antihypertensive Agents; Drug Interactions; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2006 |
[Combination therapy in contemporary strategy of treatment of arterial hypertension. Review of data on efficacy and safety of fixed combination valsartan and hydrochlorothiazide].
Topics: Angiotensin II Type 1 Receptor Blockers; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Valine; Valsartan | 2006 |
Evaluation of the dose response with valsartan and valsartan/hydrochlorothiazide in patients with essential hypertension.
Topics: Antihypertensive Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2007 |
A review of telmisartan in the treatment of hypertension: blood pressure control in the early morning hours.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Drug Therapy, Combination; Humans; Hypertension; Telmisartan; Tetrazoles; Valine; Valsartan | 2006 |
[ARB: characteristics, mechanisms of action, pharmacokinetics, indication, contraindication, clinical data, and side effects].
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Contraindications; Heart Failure; Humans; Hypertension; Imidazoles; Losartan; Telmisartan; Tetrazoles; Valine; Valsartan | 2007 |
Time to achieve blood-pressure goal: influence of dose of valsartan monotherapy and valsartan and hydrochlorothiazide combination therapy.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Randomized Controlled Trials as Topic; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2007 |
Pathophysiology of target-organ disease: does angiotensin II remain the key?
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Disease Progression; Humans; Hypertension; Losartan; Myocardial Infarction; Renin; Renin-Angiotensin System; Stroke; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2007 |
Risk reduction by preventing stroke: need for blockade of angiotensin II and catecholamines?
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Catecholamines; Humans; Hypertension; Imidazoles; Norepinephrine; Stroke; Tetrazoles; Thiophenes; Valine; Valsartan | 2007 |
[A first drug combination for the treatment of arterial hypertension with a calcium channel antagonist (amlodipine besylate) and an angiotensin receptor blocker (valsartan): Exforge].
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Drug Combinations; Humans; Hypertension; Tetrazoles; Valine; Valsartan | 2007 |
Amlodipine/Valsartan: fixed-dose combination in hypertension.
Topics: Amlodipine; Amlodipine, Valsartan Drug Combination; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Drug Combinations; Drug Synergism; Humans; Hypertension; Tetrazoles; Valine; Valsartan | 2008 |
Role of combination therapy in the treatment of hypertension: focus on valsartan plus amlodipine.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hypertension; Life Style; Tetrazoles; Valine; Valsartan | 2008 |
Angiotensin II receptor antagonists. Potential in elderly patients with cardiovascular disease.
Topics: Aged; Aged, 80 and over; Aging; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Cardiovascular Diseases; Clinical Trials as Topic; Heart Failure; Humans; Hypertension; Imidazoles; Kidney Diseases; Losartan; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 1997 |
Valsartan. A review of its pharmacology and therapeutic use in essential hypertension.
Topics: Antihypertensive Agents; Cardiomegaly; Humans; Hypertension; Receptors, Angiotensin; Renal Insufficiency; Tetrazoles; Valine; Valsartan | 1997 |
Angiotensin II receptor blockers in hypertension and renal disease.
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Hypertension; Kidney Diseases; Losartan; Tetrazoles; Valine; Valsartan | 1998 |
[New prospects in the treatment of arterial hypertension. Antagonist of angiotensin II valsartan (diovan)].
Topics: Angiotensin II; Antihypertensive Agents; Humans; Hypertension; Safety; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1998 |
Valsartan and the kidney: present and future.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Humans; Hypertension; Kidney Diseases; Renal Insufficiency; Tetrazoles; Valine; Valsartan | 1999 |
Valsartan/hydrochlorothiazide.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Drug Combinations; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Valine; Valsartan | 1999 |
Angiotensin-II receptor antagonists: their place in therapy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Drug Administration Schedule; Drug Interactions; Heart Failure; Humans; Hypertension; Irbesartan; Losartan; Renin-Angiotensin System; Telmisartan; Tetrazoles; Valine; Valsartan | 1999 |
Clinical advantage of valsartan.
Topics: Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Humans; Hypertension; Losartan; Tetrazoles; Valine; Valsartan | 1999 |
Long-term potential of angiotensin receptor blockade for cardiovascular protection in hypertension: the VALUE trial. Valsartan Antihypertensive Long-term Use Evaluation.
Topics: Amlodipine; Animals; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Clinical Trials as Topic; Humans; Hypertension; Tetrazoles; Valine; Valsartan | 1999 |
Angiotensin II receptor antagonists in the treatment of hypertension.
Topics: Algorithms; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypertension; Irbesartan; Losartan; Receptors, Angiotensin; Telmisartan; Tetrazoles; Valine; Valsartan | 1999 |
[Antihypertensive advantages of angiotensin II AT1 receptor antagonism].
Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Anti-Arrhythmia Agents; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Clinical Trials as Topic; Heart Diseases; Heart Failure; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 1999 |
Therapeutic options in minimizing left ventricular hypertrophy.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Cardiovascular Diseases; Humans; Hypertension; Hypertrophy, Left Ventricular; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2000 |
Angiotensin II antagonists for hypertension: are there differences in efficacy?
Topics: Angiotensin II; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Humans; Hypertension; Irbesartan; Losartan; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2000 |
[Use of angiotensin-II-antagonists in hypertension].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Hypertension; Losartan; Randomized Controlled Trials as Topic; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan | 2000 |
Prospective trials of angiotensin receptor blockers: beyond blood pressure control.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Hypertension; Losartan; Myocardial Infarction; Tetrazoles; Valine; Valsartan | 2000 |
Therapeutic trials comparing angiotensin converting enzyme inhibitors and angiotensin II receptor blockers.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Humans; Hypertension; Losartan; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2000 |
Valsartan: a novel angiotensin type 1 receptor antagonist.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Clinical Trials as Topic; Heart Failure; Humans; Hypertension; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Valine; Valsartan | 2000 |
Angiotensin receptor blockers and aldosterone antagonists in chronic heart failure.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Heart Failure; Humans; Hypertension; Losartan; Mineralocorticoid Receptor Antagonists; Renin-Angiotensin System; Spironolactone; Tetrazoles; Valine; Valsartan | 2001 |
[Angiotensin receptor blockers--significance for the therapy of hypertension].
Topics: Acrylates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Austria; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Prodrugs; Telmisartan; Tetrazoles; Therapeutic Equivalency; Thiophenes; Valine; Valsartan | 2001 |
Angiotensin receptor blockers -- finally the evidence is coming in: IDNT and RENAAL.
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Diabetes Mellitus, Type 2; Humans; Hypertension; Irbesartan; Kidney Failure, Chronic; Losartan; Tetrazoles; Valine; Valsartan | 2001 |
[Angiotensin II receptor blockers: current status and future prospects].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Drug Therapy, Combination; Heart Diseases; Humans; Hypertension; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2002 |
[Irbesartan: a new possibility in the treatment of hypertension].
Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Atenolol; Benzimidazoles; Benzoates; Biological Availability; Biphenyl Compounds; Controlled Clinical Trials as Topic; Drug Administration Schedule; Enalapril; Half-Life; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan | 2002 |
411 trial(s) available for valsartan and Hypertension
| Article | Year |
|---|---|
Efficacy of sacubitril/valsartan versus olmesartan in Japanese patients with essential hypertension: a randomized, double-blind, multicenter study.
Topics: Aminobutyrates; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Essential Hypertension; Humans; Hypertension; Imidazoles; Japan; Tetrazoles; Treatment Outcome; Valsartan | 2022 |
Efficacy and safety of Tengfu Jiangya tablet combined with valsartan/amlodipine in the treatment of stage 2 hypertension: study protocol for a randomized controlled trial.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Drugs, Chinese Herbal; Humans; Hypertension; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Tablets; Valsartan | 2022 |
The Difference between Sacubitril Valsartan and Valsartan on Vascular Endothelial Function, APN, MMP-9, and BNP Levels in Patients with Hypertension and Chronic Heart Failure.
Topics: Adiponectin; Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Carotid Intima-Media Thickness; Drug Combinations; Endothelium; Heart Failure; Humans; Hypertension; Matrix Metalloproteinase 9; Natriuretic Peptide, Brain; Stroke Volume; Treatment Outcome; Valsartan; Ventricular Function, Left | 2022 |
Effects of Qingda granule on patients with grade 1 hypertension at low-medium risk: study protocol for a randomized, controlled, double-blind clinical trial.
Topics: Double-Blind Method; Drugs, Chinese Herbal; Humans; Hypertension; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Treatment Outcome; Valsartan | 2023 |
Effect of Sacubitril/Valsartan vs Valsartan on Left Atrial Volume in Patients With Pre-Heart Failure With Preserved Ejection Fraction: The PARABLE Randomized Clinical Trial.
Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Diabetes Mellitus, Type 2; Female; Heart Atria; Heart Failure; Humans; Hypertension; Male; Natriuretic Peptide, Brain; Neprilysin; Stroke Volume; Tetrazoles; Valsartan | 2023 |
Twenty-Four-Hour Blood Pressure-Lowering Efficacy of Sacubitril/Valsartan Versus Olmesartan in Japanese Patients With Essential Hypertension Based on Nocturnal Blood Pressure Dipping Status: A Post Hoc Analysis of Data From a Randomized, Double-Blind Mult
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; East Asian People; Essential Hypertension; Humans; Hypertension; Tetrazoles; Valsartan | 2023 |
Effect of sacubitril/valsartan or valsartan on ventricular remodeling and myocardial fibrosis in perimenopausal women with hypertension.
Topics: Aminobutyrates; Biphenyl Compounds; Drug Combinations; Female; Heart Failure; Humans; Hypertension; Perimenopause; Prospective Studies; Valsartan; Ventricular Remodeling | 2023 |
Middle-Aged and Older Patients With Left Ventricular Hypertrophy: Higher Mortality With Drug Treated Systolic Blood Pressure Below 130 mm Hg.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Electrocardiography; Humans; Hypertension; Hypertrophy, Left Ventricular; Middle Aged; Valsartan | 2023 |
Circulating microparticles and central blood pressure according to antihypertensive strategy.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Cell-Derived Microparticles; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Rosuvastatin Calcium; Valsartan | 2019 |
Clinical effect and safety of nifedipine controlled-release tablets combined with valsartan in the treatment of primary hypertension.
Topics: Aged; Antihypertensive Agents; Calcium Channel Blockers; Delayed-Action Preparations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Valsartan | 2019 |
Valsartan Versus Amlodipine Effect on Left Ventricular Multidirectional Deformation and Adipocytokines Levels in Hypertensive Patients: Speckle Tracking Echocardiography.
Topics: Adipokines; Adiponectin; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; C-Reactive Protein; Calcium Channel Blockers; Echocardiography; Egypt; Female; Humans; Hypertension; Leptin; Male; Middle Aged; Predictive Value of Tests; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha; Valsartan; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Amlodipine/valsartan fixed-dose combination treatment in the management of hypertension: A double-blind, randomized trial.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Valsartan | 2020 |
Combined treatment with valsartan and fluvastatin to delay disease progression in nonpermanent atrial fibrillation with hypertension: A clinical trial.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Atrial Fibrillation; Blood Pressure; Disease Progression; Drug Therapy, Combination; Female; Fluvastatin; Heart Rate; Humans; Hypertension; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Valsartan | 2020 |
Comparative effects of valsartan plus cilnidipine or hydrochlorothiazide on nocturnal home blood pressure.
Topics: Antihypertensive Agents; Blood Pressure; Dihydropyridines; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2021 |
Effects of the valsartan/amlodipine combination and nifedipine gastrointestinal therapeutic system monotherapy on brachial pulse pressure and radial augmentation index in hypertensive patients.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Nifedipine; Tetrazoles; Treatment Outcome; Valsartan | 2021 |
Sacubitril-valsartan as a treatment for apparent resistant hypertension in patients with heart failure and preserved ejection fraction.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Double-Blind Method; Drug Combinations; Heart Failure; Humans; Hypertension; Neprilysin; Stroke Volume; Tetrazoles; Treatment Outcome; Valsartan | 2021 |
Efficacy and Safety of Crystalline Valsartan/Sacubitril (LCZ696) Compared With Placebo and Combinations of Free Valsartan and Sacubitril in Patients With Systolic Hypertension: The RATIO Study.
Topics: Aged; Aminobutyrates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Argentina; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Drug Combinations; Europe; Female; Humans; Hypertension; India; Male; Middle Aged; Neprilysin; North America; Protease Inhibitors; Republic of Korea; Systole; Tetrazoles; Time Factors; Treatment Outcome; Valsartan | 2017 |
Effects of valsartan and amlodipine on oxidative stress in type 2 diabetic patients with hypertension: a randomized, multicenter study.
Topics: Amlodipine; Antihypertensive Agents; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Male; Middle Aged; Oxidative Stress; Valsartan | 2017 |
Evaluation of Pharmacokinetic and Pharmacodynamic Drug-Drug Interaction of Sacubitril/Valsartan (LCZ696) and Sildenafil in Patients With Mild-to-Moderate Hypertension.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Atrial Natriuretic Factor; Biphenyl Compounds; Blood Pressure; Cyclic GMP; Double-Blind Method; Drug Combinations; Drug Interactions; Humans; Hypertension; Male; Middle Aged; Sildenafil Citrate; Tetrazoles; Valsartan | 2018 |
Patient characteristics do not predict the individual response to antihypertensive medication: a cross-over trial.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Family Practice; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Netherlands; Practice Guidelines as Topic; Prognosis; Prospective Studies; Valsartan | 2018 |
Efficacy and Safety of Sacubitril/Valsartan (LCZ696) Compared With Olmesartan in Elderly Asian Patients (≥65 Years) With Systolic Hypertension.
Topics: Aged; Aged, 80 and over; Aminobutyrates; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Asian People; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Imidazoles; Male; Tetrazoles; Treatment Outcome; Valsartan | 2017 |
24-Hour blood pressure response to lower dose (30 mg) fimasartan in Korean patients with mild to moderate essential hypertension.
Topics: Aged; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Pyrimidines; Tetrazoles; Valsartan | 2017 |
Effect of Sacubitril/Valsartan on Exercise-Induced Lipid Metabolism in Patients With Obesity and Hypertension.
Topics: Adipose Tissue; Aminobutyrates; Amlodipine; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Combinations; Drug Monitoring; Exercise; Female; Humans; Hypertension; Lipid Metabolism; Male; Middle Aged; Natriuretic Peptides; Neprilysin; Obesity, Abdominal; Tetrazoles; Treatment Outcome; Valsartan | 2018 |
The efficacy and safety of valsartan and a combination of valsartan and hydrochlorothiazide in the treatment of patients with mild to moderate arterial hypertension: a subgroup analysis of the effect of valsartan and its combination with….
Topics: Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Pulse Wave Analysis; Treatment Outcome; Valsartan | 2018 |
Comparative effects of valsartan plus either cilnidipine or hydrochlorothiazide on home morning blood pressure surge evaluated by information and communication technology-based nocturnal home blood pressure monitoring.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Blood Pressure Monitors; Dihydropyridines; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Medical Informatics; Middle Aged; Outcome Assessment, Health Care; Valsartan | 2018 |
Efficacy and safety of sacubitril/valsartan in patients with essential hypertension uncontrolled by olmesartan: A randomized, double-blind, 8-week study.
Topics: Aged; Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Combinations; Drug Monitoring; Drug Resistance; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valsartan | 2018 |
Central and cerebral haemodynamic changes after antihypertensive therapy in ischaemic stroke patients: A double-blind randomised trial.
Topics: Aged; Antihypertensive Agents; Atenolol; Biphenyl Compounds; Cerebrovascular Circulation; Double-Blind Method; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Pyrimidines; Stroke; Tetrazoles; Treatment Outcome; Valsartan | 2018 |
The effects of angiotensin receptor neprilysin inhibition by sacubitril/valsartan on adipose tissue transcriptome and protein expression in obese hypertensive patients.
Topics: Adipose Tissue; Adult; Aminobutyrates; Amlodipine; Angiotensin Receptor Antagonists; Biphenyl Compounds; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Neprilysin; Obesity; Proteins; Subcutaneous Fat; Tetrazoles; Transcriptome; Valsartan | 2018 |
Clinical efficacy and ultrasound inspection of the treatment of hypertensive heart patients with Valsartan combined with hydrochlorothiazide.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Echocardiography; Female; Heart Diseases; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Treatment Outcome; Valsartan; Ventricular Function, Left | 2018 |
Upstream therapeutic strategies of valsartan and fluvastatin on hypertensive patients with non-permanent atrial fibrillation.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Anti-Arrhythmia Agents; Antihypertensive Agents; Atrial Fibrillation; Blood Pressure; China; Disease Progression; Female; Fluvastatin; Heart Rate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Incidence; Male; Middle Aged; Prospective Studies; Recurrence; Time Factors; Treatment Outcome; Valsartan | 2018 |
Long-term safety and tolerability of valsartan in children aged 6 to 17 years with hypertension.
Topics: Adolescent; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Child; Cough; Creatinine; Drug Therapy, Combination; Female; Fever; Glomerular Filtration Rate; Headache; Humans; Hypertension; Male; Nasopharyngitis; Prospective Studies; Proteinuria; Renal Insufficiency, Chronic; Serum Albumin, Human; Severity of Illness Index; Time Factors; Treatment Outcome; Valsartan | 2019 |
Outcomes and Effect of Treatment According to Etiology in HFrEF: An Analysis of PARADIGM-HF.
Topics: Aged; Aminobutyrates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Cardiomyopathy, Alcoholic; Cardiomyopathy, Dilated; Cardiotoxicity; Cardiovascular Diseases; Cause of Death; Dangerous Behavior; Diabetic Cardiomyopathies; Drug Combinations; Enalapril; Female; Heart Failure; Heart Valve Diseases; Hospitalization; Humans; Hypertension; Infections; Male; Middle Aged; Mortality; Myocardial Ischemia; Peripartum Period; Stroke Volume; Tetrazoles; Treatment Outcome; Valsartan; Virus Diseases | 2019 |
Pharmacokinetic Drug Interactions Between Amlodipine, Valsartan, and Rosuvastatin in Healthy Volunteers.
Topics: Adult; Amlodipine; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Healthy Volunteers; Humans; Hypertension; Male; Middle Aged; Rosuvastatin Calcium; Valsartan | 2019 |
Efficacy and safety of valsartan in hypertensive children 6 months to 5 years of age.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Child, Preschool; Double-Blind Method; Female; Humans; Hypertension; Infant; Male; Tetrazoles; Valine; Valsartan | 2013 |
Impact of angiotensin II receptor blocker therapy (olmesartan or valsartan) on coronary atherosclerotic plaque volume measured by intravascular ultrasound in patients with stable angina pectoris.
Topics: Aged; Aged, 80 and over; Angina Pectoris; Angioplasty, Balloon, Coronary; Angiotensin II Type 1 Receptor Blockers; Combined Modality Therapy; Coronary Artery Disease; Disease Progression; Double-Blind Method; Female; Humans; Hypertension; Image Interpretation, Computer-Assisted; Imidazoles; Long-Term Care; Male; Middle Aged; Tetrazoles; Ultrasonography, Interventional; Valine; Valsartan | 2013 |
Effects of CPAP on "vascular" risk factors in patients with obstructive sleep apnea and arterial hypertension.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arterial Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Continuous Positive Airway Pressure; Diuretics; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Manometry; Middle Aged; Polysomnography; Predictive Value of Tests; Pulse Wave Analysis; Risk Factors; Russia; Severity of Illness Index; Sleep Apnea, Obstructive; Tetrazoles; Treatment Outcome; Valine; Valsartan; Vascular Stiffness | 2013 |
Effects of demographics on the antihypertensive efficacy of triple therapy with amlodipine, valsartan, and hydrochlorothiazide for moderate to severe hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Demography; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Valine; Valsartan; Young Adult | 2013 |
Efficacy of newer versus older antihypertensive drugs in black patients living in sub-Saharan Africa.
Topics: Adult; Africa South of the Sahara; Amlodipine; Antihypertensive Agents; Bisoprolol; Black People; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2013 |
Effect of naproxen and acetaminophen on blood pressure lowering by ramipril, valsartan and aliskiren in hypertensive patients.
Topics: Acetaminophen; Adult; Aged; Amides; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Interactions; Female; Fumarates; Humans; Hypertension; Male; Middle Aged; Naproxen; Ramipril; Tetrazoles; Valine; Valsartan | 2013 |
Efficacy and safety of valsartan and amlodipine single-pill combination in hypertensive patients (PEAK study).
Topics: Administration, Oral; Aged; Amlodipine; Antihypertensive Agents; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Patient Compliance; Tetrazoles; Treatment Outcome; Turkey; Valine; Valsartan | 2013 |
Effect of renin-angiotensin system blockade on soluble Klotho in patients with type 2 diabetes, systolic hypertension, and albuminuria.
Topics: Aged; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Biomarkers; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diuretics; Female; Glucuronidase; Hospitals, University; Humans; Hydrochlorothiazide; Hypertension; Klotho Proteins; London; Male; Middle Aged; Phosphates; Pulse Wave Analysis; Renin-Angiotensin System; Systole; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2013 |
Ambulatory blood pressure response to once-daily fimasartan: an 8-week, multicenter, randomized, double-blind, active-comparator, parallel-group study in Korean patients with mild to moderate essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Administration Schedule; Essential Hypertension; Female; Headache; Humans; Hypertension; Korea; Male; Middle Aged; Pyrimidines; Republic of Korea; Tetrazoles; Valine; Valsartan; Young Adult | 2013 |
Determinants of achieving early blood pressure control with monotherapy in a primary care setting.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Disease Management; Female; Humans; Hypertension; Male; Middle Aged; Primary Health Care; Sex Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2013 |
Effects of valsartan versus amlodipine in diabetic hypertensive patients with or without previous cardiovascular disease.
Topics: Aged; Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Case-Control Studies; Death, Sudden, Cardiac; Diabetes Mellitus, Type 2; Female; Heart Failure; Hospitalization; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion; Proportional Hazards Models; Stroke; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2013 |
Comparative effects of telmisartan and valsartan as add-on agents for hypertensive patients with morning blood pressure insufficiently controlled by amlodipine monotherapy.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Chemical Analysis; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Therapy, Combination; Endpoint Determination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Sleep; Telmisartan; Tetrazoles; Valine; Valsartan | 2014 |
Destiffening effect of valsartan and atenolol: influence of heart rate and blood pressure.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Pulse Wave Analysis; Tetrazoles; Valine; Valsartan; Vascular Stiffness | 2014 |
Efficacy and safety of LCZ696, a first-in-class angiotensin receptor neprilysin inhibitor, in Asian patients with hypertension: a randomized, double-blind, placebo-controlled study.
Topics: Aged; Aminobutyrates; Angioedema; Angiotensin Receptor Antagonists; Asian People; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; China; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Incidence; Japan; Male; Middle Aged; Neprilysin; Republic of Korea; Taiwan; Tetrazoles; Thailand; Treatment Outcome; Valsartan | 2014 |
Rationale and study design of the Prospective comparison of Angiotensin Receptor neprilysin inhibitor with Angiotensin receptor blocker MEasuring arterial sTiffness in the eldERly (PARAMETER) study.
Topics: Aged; Aminobutyrates; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Double-Blind Method; Drug Combinations; Drug Monitoring; Female; Hemodynamics; Humans; Hypertension; Imidazoles; Male; Middle Aged; Neprilysin; Prospective Studies; Research Design; Tetrazoles; Treatment Outcome; Valsartan; Vascular Stiffness | 2014 |
Effects of valsartan treatment on serum ghrelin level and left ventricular mass index in patients with untreated primary hypertension.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Case-Control Studies; Echocardiography; Enzyme-Linked Immunosorbent Assay; Female; Ghrelin; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Prospective Studies; Treatment Outcome; Valsartan | 2014 |
More rigorous protocol adherence to intensive structured management improves blood pressure control in primary care: results from the Valsartan Intensified Primary carE Reduction of Blood Pressure study.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Female; Humans; Hypertension; Male; Middle Aged; Patient Compliance; Primary Health Care; Prospective Studies; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2014 |
Efficacy and safety of nebivolol and valsartan as fixed-dose combination in hypertension: a randomised, multicentre study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzopyrans; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Ethanolamines; Female; Humans; Hypertension; Male; Middle Aged; Nebivolol; Tetrazoles; Treatment Outcome; Valine; Valsartan; Young Adult | 2014 |
Randomized trial comparing the effects of a low-dose combination of nifedipine GITS and valsartan versus high-dose monotherapy on central hemodynamics in patients with inadequately controlled hypertension: FOCUS study.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Male; Manometry; Middle Aged; Nifedipine; Prospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan; Young Adult | 2014 |
Effect of add-on aliskiren to type 1 angiotensin receptor blocker therapy on endothelial function and autonomic nervous system in hypertensive patients with ischemic heart disease.
Topics: Aged; Amides; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Autonomic Nervous System; Comorbidity; Drug Therapy, Combination; Endothelium, Vascular; Female; Fumarates; Heart Rate; Humans; Hypertension; Male; Middle Aged; Myocardial Ischemia; Renin; Tetrazoles; Treatment Outcome; Valine; Valsartan; Vasodilation | 2014 |
Efficacy and safety of 30-mg fimasartan for the treatment of patients with mild to moderate hypertension: an 8-week, multicenter, randomized, double-blind, phase III clinical study.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Pyrimidines; Tetrazoles; Treatment Outcome; Valsartan | 2014 |
[The influence of citoflavin on molecular mechanisms of hypertensive encephalopathy development in patients with systolic arterial hypertension].
Topics: Aged; Aged, 80 and over; Amlodipine; Aspirin; Atorvastatin; Blood Pressure; Blood Proteins; Drug Combinations; Drug Therapy, Combination; Echocardiography; Female; Flavin Mononucleotide; Hemodynamics; Heptanoic Acids; Humans; Hypertension; Hypertensive Encephalopathy; Inosine Diphosphate; Male; Neuroprotective Agents; Niacinamide; Pyrroles; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Succinates; Systole; Tetrazoles; Valine; Valsartan | 2014 |
[Optimization of arterial hypertension management by the use of two- and three-drugs fixed dose combinations at the daily stay department].
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Day Care, Medical; Dose-Response Relationship, Drug; Drug Combinations; Drug Monitoring; Drug Synergism; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2014 |
Time of administration important? Morning versus evening dosing of valsartan.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cardiovascular Diseases; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Middle Aged; Risk Factors; Treatment Outcome; Valsartan | 2015 |
Aortic remodelling following the treatment and regression of hypertensive left ventricular hypertrophy: a cardiovascular magnetic resonance study.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Aorta, Thoracic; Bendroflumethiazide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Essential Hypertension; Female; Follow-Up Studies; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Magnetic Resonance Imaging, Cine; Male; Middle Aged; Sympatholytics; Treatment Outcome; Valsartan; Vascular Remodeling; Vascular Stiffness | 2015 |
Evening versus morning dosing of antihypertensive drugs in hypertensive patients with sleep apnoea: a cross-over study.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Continuous Positive Airway Pressure; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Sleep Apnea, Obstructive; Valsartan | 2015 |
Comparison of single-pill strategies first line in hypertension: perindopril/amlodipine versus valsartan/amlodipine.
Topics: Adult; Aged; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Indapamide; Male; Middle Aged; Perindopril; Valsartan | 2015 |
Endocan, a novel marker of endothelial dysfunction in patients with essential hypertension: comparative effects of amlodipine and valsartan.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; C-Reactive Protein; Endothelium, Vascular; Essential Hypertension; Female; Humans; Hypertension; Male; Middle Aged; Neoplasm Proteins; Proteoglycans; Tetrazoles; Valine; Valsartan | 2015 |
Long-term safety of nebivolol and valsartan combination therapy in patients with hypertension: an open-label, single-arm, multicenter study.
Topics: Antihypertensive Agents; Benzopyrans; Drug Combinations; Ethanolamines; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nebivolol; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2014 |
Valsartan decreases platelet activity and arterial thrombotic events in elderly patients with hypertension.
Topics: Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Blood Platelets; Blotting, Western; Cell Line; Cyclooxygenase 2; Female; Humans; Hypertension; Male; Platelet Aggregation; Real-Time Polymerase Chain Reaction; Tetrazoles; Thrombosis; Thromboxane B2; Valine; Valsartan | 2015 |
Safety and efficacy of LCZ696, a first-in-class angiotensin receptor neprilysin inhibitor, in Japanese patients with hypertension and renal dysfunction.
Topics: Aged; Aminobutyrates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Asian People; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Drug Combinations; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney Diseases; Kidney Function Tests; Male; Middle Aged; Neprilysin; Tetrazoles; Valsartan | 2015 |
Different chronotherapeutic effects of valsartan and olmesartan in non-dipper hypertensive patients during valsartan treatment at morning.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Creatinine; Drug Chronotherapy; Female; Glomerular Filtration Rate; Humans; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Valsartan | 2015 |
Ambulatory 24-hour cardiac oxygen consumption and blood pressure-heart rate variability: effects of nebivolol and valsartan alone and in combination.
Topics: Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Myocardium; Nebivolol; Oxygen Consumption; Random Allocation; Valsartan | 2015 |
Evaluation of the Efficacy and Safety of the Lercanidipine/Valsartan Combination in Korean Patients With Essential Hypertension Not Adequately Controlled With Lercanidipine Monotherapy: A Randomized, Multicenter, Parallel Design, Phase III Clinical Trial.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Dihydropyridines; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Essential Hypertension; Female; Headache; Humans; Hypertension; Male; Middle Aged; Treatment Outcome; Valsartan; Young Adult | 2015 |
Choice of Antihypertensive Combination Therapy Based on Daily Salt Intake.
Topics: Aged; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Metabolic Syndrome; Middle Aged; Potassium; Prospective Studies; Sodium; Sodium Chloride, Dietary; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2015 |
The effects of angiotensin II signaling blockade on platelet activity in subjects with hypertension.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Female; Humans; Hypertension; Life Style; Male; Middle Aged; Perindopril; Platelet Function Tests; Treatment Outcome; Valsartan | 2015 |
Upstream therapeutic strategies of Valsartan and Fluvastatin on Hypertensive patients with non-permanent Atrial Fibrillation (VF-HT-AF): study protocol for a randomized controlled trial.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Atrial Fibrillation; Blood Pressure; China; Clinical Protocols; Electrocardiography, Ambulatory; Fatty Acids, Monounsaturated; Fluvastatin; Heart Failure; Heart Rate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Indoles; Myocardial Infarction; Prospective Studies; Recurrence; Research Design; Risk Assessment; Risk Factors; Shock, Cardiogenic; Time Factors; Treatment Outcome; Valsartan | 2015 |
Efficacy and safety of two single-pill fixed-dose combinations of angiotensin II receptor blockers/calcium channel blockers in hypertensive patients (EXAMINER study).
Topics: Aged; Amlodipine; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Drug Combinations; Drug Monitoring; Female; Humans; Hypertension; Irbesartan; Male; Middle Aged; Tetrazoles; Treatment Outcome; Triglycerides; Uric Acid; Valsartan | 2016 |
Correlations of plasma renin activity and aldosterone concentration with ambulatory blood pressure responses to nebivolol and valsartan, alone and in combination, in hypertension.
Topics: Aldosterone; Blood Pressure Monitoring, Ambulatory; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Male; Maximum Tolerated Dose; Nebivolol; Patient Selection; Renin; Renin-Angiotensin System; Risk Assessment; Severity of Illness Index; Treatment Outcome; Valsartan | 2015 |
Effect of aliskiren on vascular remodelling in small retinal circulation.
Topics: Adult; Aged; Amides; Antihypertensive Agents; Arterioles; Blood Pressure; Double-Blind Method; Essential Hypertension; Female; Fumarates; Humans; Hypertension; Laser-Doppler Flowmetry; Male; Middle Aged; Pulse Wave Analysis; Retinal Vessels; Valsartan; Vascular Remodeling | 2015 |
LCZ696, a First-in-Class Angiotensin Receptor-Neprilysin Inhibitor: The First Clinical Experience in Patients With Severe Hypertension.
Topics: Aged; Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Neprilysin; Severity of Illness Index; Tetrazoles; Time Factors; Treatment Outcome; Valsartan | 2016 |
No evidence for a J-shaped curve in treated hypertensive patients with increased cardiovascular risk: The VALUE trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Coronary Artery Disease; Diastole; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Prognosis; Proportional Hazards Models; Prospective Studies; Risk Factors; Stroke; Systole; Treatment Outcome; Valsartan | 2016 |
Cardiovascular outcomes at different on-treatment blood pressures in the hypertensive patients of the VALUE trial.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Male; Myocardial Infarction; Risk Factors; Stroke; Treatment Outcome; Valsartan | 2016 |
Predictors of cardiac morbidity in diabetic, new-onset diabetic and non-diabetic high-risk hypertensive patients: The Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Complications; Female; Heart Failure; Hospitalization; Humans; Hypertension; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Risk Factors; Valsartan | 2016 |
The Effects of Valsartan and Amlodipine on the Levels of Irisin, Adropin, and Perilipin.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Proteins; Calcium; Carrier Proteins; Female; Fibronectins; Humans; Hypertension; Intercellular Signaling Peptides and Proteins; Male; Middle Aged; Obesity; Peptides; Perilipin-1; Phosphoproteins; Valsartan | 2015 |
Safety of the Up-titration of Nifedipine GITS and Valsartan or Low-dose Combination in Uncontrolled Hypertension: the FOCUS Study.
Topics: Adult; Aged; Antihypertensive Agents; Humans; Hypertension; Middle Aged; Nifedipine; Prospective Studies; Valsartan; Young Adult | 2016 |
Improvement in Retinal Capillary Rarefaction After Valsartan Treatment in Hypertensive Patients.
Topics: Adult; Aged; Antihypertensive Agents; Capillaries; Double-Blind Method; Female; Humans; Hypertension; Male; Microcirculation; Middle Aged; Retinal Vessels; Treatment Outcome; Valsartan | 2016 |
The efficacy and safety of valsartan and combination of valsartan and hydrochlorothiazide in the treatment of patients with mild to moderate arterial hypertension - the VICTORY trial.
Topics: Adult; Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Safety; Prospective Studies; Treatment Outcome; Valsartan | 2017 |
Effects of Sacubitril/Valsartan (LCZ696) on Natriuresis, Diuresis, Blood Pressures, and NT-proBNP in Salt-Sensitive Hypertension.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Diuresis; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Natriuresis; Natriuretic Peptide, Brain; Peptide Fragments; Sodium Chloride, Dietary; Tetrazoles; Time Factors; Valsartan | 2017 |
Long-term (52-week) safety and efficacy of Sacubitril/valsartan in Asian patients with hypertension.
Topics: Adult; Aminobutyrates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Asian People; Biphenyl Compounds; Blood Pressure; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hypertension; Incidence; Male; Middle Aged; Patient Safety; Tetrazoles; Treatment Outcome; Valsartan | 2017 |
Efficacy and safety of sacubitril/valsartan (LCZ696) add-on to amlodipine in Asian patients with systolic hypertension uncontrolled with amlodipine monotherapy.
Topics: Aged; Aminobutyrates; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Asian People; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Systole; Tetrazoles; Treatment Outcome; Valsartan | 2017 |
Effects of Amlodipine and Valsartan on Blood Pressure Variability and Pulse Wave Velocity in Hypertensive Patients.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hypertension; Male; Middle Aged; Pulse Wave Analysis; Valsartan | 2017 |
Predictors of new-onset diabetes mellitus in hypertensive patients: the VALUE trial.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Calcium Channel Blockers; Diabetes Mellitus; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; Humans; Hypertension; Incidence; Middle Aged; Prognosis; Prospective Studies; Risk Factors; Tetrazoles; Time Factors; Valine; Valsartan | 2008 |
Reaching the therapeutic goal in hypertension: results from the Canadian valsartan observational study. (Diovantage 4).
Topics: Aged; Antihypertensive Agents; Blood Pressure; Canada; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Compliance; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Efficacy, safety and tolerability of valsartan 80 mg compared to irbesartan 150 mg in hypertensive patients on long-term hemodialysis (VALID study).
Topics: Aged; Antihypertensive Agents; Biphenyl Compounds; Cross-Over Studies; Female; Humans; Hypertension; Irbesartan; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Improving blood pressure control: increase the dose of diuretic or switch to a fixed-dose angiotensin receptor blocker/diuretic? the valsartan hydrochlorothiazide diuretic for initial control and titration to achieve optimal therapeutic effect (Val-DICTAT
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Chi-Square Distribution; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Least-Squares Analysis; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Efficacy and safety of the Angiotensin receptor blocker valsartan in children with hypertension aged 1 to 5 years.
Topics: Administration, Oral; Age Factors; Angiotensin II Type 1 Receptor Blockers; Child, Preschool; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Infant; Male; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Efficacy and tolerability of combination therapy with valsartan/hydrochlorothiazide in the initial treatment of severe hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Diuretics; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Progressive effects of valsartan compared with amlodipine in prevention of diabetes according to categories of diabetogenic risk in hypertensive patients: the VALUE trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Follow-Up Studies; Humans; Hypertension; Middle Aged; Multivariate Analysis; Regression Analysis; Risk Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Achieving BP goals with valsartan and HCTZ alone and in combination: pooled analysis of two randomized, double-blind, placebo-controlled studies.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebos; Retrospective Studies; Tetrazoles; Valine; Valsartan | 2008 |
Combination therapy with valsartan/hydrochlorothiazide at doses up to 320/25 mg improves blood pressure levels in patients with hypertension inadequately controlled by valsartan 320 mg monotherapy.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2008 |
Combination antihypertensive therapy with valsartan and hydrochlorothiazide in Chinese patients with mild-to-moderate hypertension.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Asian People; Blood Pressure; China; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Time Factors; Valine; Valsartan | 2008 |
Rationale and design of the KYOTO HEART study: effects of valsartan on morbidity and mortality in uncontrolled hypertensive patients with high risk of cardiovascular events.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Cardiovascular Diseases; Drug Therapy, Combination; Female; Humans; Hypertension; Japan; Male; Prospective Studies; Research Design; Risk Assessment; Risk Factors; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2009 |
[Effect of valsartan on postprandial plasma inflammatory factors in patients with essential hypertension].
Topics: Adult; Aged; Antihypertensive Agents; C-Reactive Protein; Dietary Fats; Female; Humans; Hypertension; Male; Middle Aged; P-Selectin; Tetrazoles; Triglycerides; Valine; Valsartan | 2008 |
Initial combination therapy compared with monotherapy in diabetic hypertensive patients.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Glucose; Blood Pressure; C-Reactive Protein; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Hypoglycemic Agents; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Effect of valsartan addition to amlodipine on insulin sensitivity in overweight-obese hypertensive patients.
Topics: Adult; Aged; Amlodipine; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Hypertension; Insulin; Male; Middle Aged; Obesity; Overweight; Prospective Studies; Tetrazoles; Valine; Valsartan | 2008 |
Coadministration of valsartan 160 and 320 mg and simvastatin 20 and 40 mg in patients with hypertension and hypercholesterolemia: a multicenter, 12-week, double-blind, double-dummy, parallel-group superiority study.
Topics: Aged; Anticholesteremic Agents; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Hypertension; Lipoproteins, LDL; Male; Middle Aged; Simvastatin; Tetrazoles; Valine; Valsartan | 2008 |
Long-term treatment with valsartan improved cyclic variation of the myocardial integral backscatter signal and diastolic dysfunction in hypertensive patients: the echocardiographic assessment.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Echocardiography; Female; Fibrosis; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardium; Prospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan; Ventricular Dysfunction, Left | 2008 |
Olmesartan reduced microalbuminuria in Japanese subjects with type 2 diabetes.
Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Asian People; Benzimidazoles; Benzoates; Biphenyl Compounds; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Telmisartan; Tetrazoles; Valine; Valsartan | 2009 |
Aliskiren and valsartan in stage 2 hypertension: subgroup analysis of a randomized, double-blind study.
Topics: Aged; Amides; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2008 |
[Economics of nephroprotection in arterial hypertension and type 2 diabetes mellitus].
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Cost-Benefit Analysis; Diabetes Mellitus, Type 2; Drug Costs; Humans; Hypertension; Irbesartan; Kidney Diseases; Tetrazoles; Valine; Valsartan | 2008 |
Metabolic and antihypertensive effects of combined angiotensin receptor blocker and diuretic therapy in prediabetic hypertensive patients with the cardiometabolic syndrome.
Topics: Adolescent; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Metabolic Syndrome; Middle Aged; Prediabetic State; Risk Factors; Tetrazoles; Valine; Valsartan; Young Adult | 2008 |
Pharmacokinetics of valsartan in pediatric and adolescent subjects with hypertension.
Topics: Administration, Oral; Adolescent; Age Factors; Antihypertensive Agents; Area Under Curve; Body Weight; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Infant; Male; Tetrazoles; Valine; Valsartan | 2009 |
Efficacy and tolerability of amlodipine/valsartan combination therapy in hypertensive patients not adequately controlled on valsartan monotherapy.
Topics: Amlodipine; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Single-Blind Method; Tetrazoles; Valine; Valsartan | 2009 |
Efficacy and safety of the single pill combination of amlodipine 10 mg plus valsartan 160 mg in hypertensive patients not controlled by amlodipine 10 mg plus olmesartan 20 mg in free combination.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Cohort Studies; Drug Combinations; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Patient Compliance; Prospective Studies; Tetrazoles; Valine; Valsartan | 2009 |
The combination of amlodipine/valsartan 5/160 mg produces less peripheral oedema than amlodipine 10 mg in hypertensive patients not adequately controlled with amlodipine 5 mg.
Topics: Aged; Amlodipine; Antihypertensive Agents; Drug Combinations; Edema; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Combination of amlodipine 10 mg and valsartan 160 mg lowers blood pressure in patients with hypertension not controlled by an ACE inhibitor/CCB combination.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Resistance; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Ramipril; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Long-term tolerability and efficacy of the combination of amlodipine/valsartan in hypertensive patients: a 54-week, open-label extension study.
Topics: Amlodipine; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Placebos; Tetrazoles; Valine; Valsartan | 2009 |
Angiotensin-receptor blockers as therapy for mild-to-moderate hypertension-associated non-alcoholic steatohepatitis.
Topics: Alanine Transaminase; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Aspartate Aminotransferases; Benzimidazoles; Benzoates; Blood Pressure; Fatty Liver; Female; Humans; Hypertension; Liver Function Tests; Male; Middle Aged; Patient Selection; Telmisartan; Tetrazoles; Valine; Valsartan | 2009 |
Effects of high sodium intake and diuretics on the circadian rhythm of blood pressure in type 2 diabetic patients treated with an angiotensin II receptor blocker.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Diabetes Mellitus, Type 2; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Japan; Losartan; Male; Middle Aged; Prospective Studies; Sodium; Sodium, Dietary; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Add-on benefits of amlodipine and thiazide in nondiabetic chronic kidney disease stage 1/2 patients treated with valsartan.
Topics: Adult; Albuminuria; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Carotid Arteries; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Renal Insufficiency, Chronic; Tetrazoles; Thiazides; Valine; Valsartan | 2009 |
Impact of supportive measures on drug adherence in patients with essential hypertension treated with valsartan: the randomized, open-label, parallel group study VALIDATE.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Medication Adherence; Middle Aged; Tetrazoles; Valine; Valsartan | 2009 |
Effects of angiotensin II type 1 receptor blocker on blood pressure variability and cardiovascular remodeling in hypertensive patients on chronic peritoneal dialysis.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Natriuretic Peptides; Peritoneal Dialysis, Continuous Ambulatory; Pulse; Tetrazoles; Valine; Valsartan; Ventricular Remodeling | 2009 |
Effectiveness of valsartan for treatment of hypertension: patient profiling and hierarchical modeling of determinants and outcomes (the PREVIEW study).
Topics: Aged; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Linear Models; Logistic Models; Male; Middle Aged; Outcome Assessment, Health Care; Patient Compliance; Practice Patterns, Physicians'; Professional Competence; Tetrazoles; Time Factors; Valine; Valsartan | 2009 |
Impact of angiotensin receptor blockade in combination with hydrochlorothiazide 25 mg in 2121 patients with stage 1-2 hypertension.
Topics: Adult; Age Factors; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Blood Pressure; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Racial Groups; Sex Factors; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Pretreatment levels of plasma renin activity predict ambulatory blood pressure response to valsartan in essential hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Humans; Hypertension; Japan; Predictive Value of Tests; Prospective Studies; Radioimmunoassay; Renin; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Effects of force-titrated valsartan/hydrochlorothiazide versus amlodipine/hydrochlorothiazide on ambulatory blood pressure in patients with stage 2 hypertension: the EVALUATE study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Effects of angiotensin II receptor blockers on relationships between 24-hour blood pressure, autonomic function, and health-related QOL.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Autonomic Nervous System; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Circadian Rhythm; Dose-Response Relationship, Drug; Female; Health Surveys; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Quality of Life; Telmisartan; Tetrazoles; Valine; Valsartan | 2009 |
Effects of angiotensin-converting enzyme inhibitor versus valsartan on cellular signaling events in heart transplant.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Creatinine; Female; Heart; Heart Transplantation; Humans; Hypertension; Male; Middle Aged; Myocardium; Potassium; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Tetrazoles; Valine; Valsartan | 2009 |
Triple antihypertensive therapy with amlodipine, valsartan, and hydrochlorothiazide: a randomized clinical trial.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Diastole; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Single-Blind Method; Systole; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Combination therapy with various combinations of aliskiren, valsartan, and hydrochlorothiazide in hypertensive patients not adequately responsive to hydrochlorothiazide alone.
Topics: Adult; Aged; Amides; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2009 |
Valsartan improves endothelial dysfunction in hypertension: a randomized, double-blind study.
Topics: Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Chemical Analysis; Blood Pressure; Cross-Over Studies; Double-Blind Method; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Nitroprusside; omega-N-Methylarginine; Regional Blood Flow; Tetrazoles; Valine; Valsartan; Vasodilator Agents | 2009 |
Effects of valsartan on morbidity and mortality in uncontrolled hypertensive patients with high cardiovascular risks: KYOTO HEART Study.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Drug Therapy, Combination; Female; Humans; Hypertension; Kaplan-Meier Estimate; Male; Prospective Studies; Risk Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Efficacy and tolerability of amlodipine/valsartan combination therapy in hypertensive patients not adequately controlled on amlodipine monotherapy.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Placebos; Tetrazoles; Treatment Failure; Treatment Outcome; Valine; Valsartan | 2009 |
Evaluation of arterial stiffness in morning hypertension under high-dose valsartan compared to valsartan plus low-dose diuretic.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Ankle Brachial Index; Blood Flow Velocity; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Pulsatile Flow; Tetrazoles; Trichlormethiazide; Valine; Valsartan | 2009 |
Antihypertensive effects of double the maximum dose of valsartan in African-American patients with type 2 diabetes mellitus and albuminuria.
Topics: Adolescent; Adult; Aged; Albuminuria; Antihypertensive Agents; Black or African American; Blood Pressure; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Renin-Angiotensin System; Tetrazoles; Treatment Outcome; Valine; Valsartan; Young Adult | 2010 |
Randomized study to compare valsartan +/- HCTZ versus amlodipine +/- HCTZ strategies to maximize blood pressure control.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Double-Blind Method; Drug Therapy, Combination; Europe; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; South America; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2009 |
Effects of angiotensin II receptor blockers on the relationships between ambulatory blood pressure and anti-hypertensive effects, autonomic function, and health-related quality of life.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Female; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Quality of Life; Sympathetic Nervous System; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Effectiveness of initiating treatment with valsartan/hydrochlorothiazide in patients with stage-1 or stage-2 hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Amlodipine/valsartan/hydrochlorothiazide triple combination therapy in moderate/severe hypertension: Secondary analyses evaluating efficacy and safety.
Topics: Adolescent; Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Tetrazoles; Valine; Valsartan | 2009 |
Influence of ATII blockers and calcium channel blockers on renal vascular resistance in patients with essential hypertension.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Croatia; Female; Humans; Hypertension; Hypertension, Renovascular; Kidney; Male; Middle Aged; Regression Analysis; Tetrazoles; Ultrasonography, Doppler, Duplex; Valine; Valsartan; Vascular Resistance | 2009 |
A comparative study of the renoprotective effects of benidipine and valsartan in primary hypertensive patients with proteinuria.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Proteinuria; Renal Circulation; Tetrazoles; Valine; Valsartan | 2009 |
[Efficacy and safety of the single pill combination of valsartan 80 mg plus amlodipine 5 mg in mild to moderate essential hypertensive patients without adequate blood pressure control by monotherapy].
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2009 |
[Impact of antihypertensive medication timing on degree and stability of blood pressure lowering in patients with essential hypertension].
Topics: Antihypertensive Agents; Blood Pressure; Drug Administration Schedule; Drug Therapy, Combination; Felodipine; Humans; Hypertension; Tetrazoles; Valine; Valsartan | 2009 |
Effect of valsartan or olmesartan addition to amlodipine on ankle edema in hypertensive patients.
Topics: Adult; Aged; Amlodipine; Ankle Joint; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Drug Therapy, Combination; Edema; Female; Heart Rate; Humans; Hypertension; Imidazoles; Male; Middle Aged; Norepinephrine; Prospective Studies; Tetrazoles; Valine; Valsartan | 2010 |
Achieving blood pressure goal: initial therapy with valsartan/hydrochlorothiazide combination compared with monotherapy.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Diuretics; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebo Effect; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2010 |
Valsartan addition to amlodipine is more effective than losartan addition in hypertensive patients inadequately controlled by amlodipine.
Topics: Adult; Aged; Amlodipine; Anthracenes; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan | 2010 |
Blood-pressure reduction with LCZ696, a novel dual-acting inhibitor of the angiotensin II receptor and neprilysin: a randomised, double-blind, placebo-controlled, active comparator study.
Topics: Aged; Aminobutyrates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Neprilysin; Tetrazoles; Valine; Valsartan | 2010 |
[Renal protective effects of benidipine and valsartan in primary hypertension patients with proteinuria].
Topics: Adult; Aged; Angiotensin Receptor Antagonists; Calcium Channel Blockers; Dihydropyridines; Female; Glomerular Filtration Rate; Humans; Hypertension; Male; Middle Aged; Proteinuria; Tetrazoles; Valine; Valsartan | 2010 |
Amlodipine-valsartan combination decreases central systolic blood pressure more effectively than the amlodipine-atenolol combination: the EXPLOR study.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Atenolol; Blood Pressure; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Multivariate Analysis; Probability; Prospective Studies; Severity of Illness Index; Single-Blind Method; Systole; Tetrazoles; Treatment Outcome; Valine; Valsartan; Young Adult | 2010 |
Rationale and design of the NAGOYA HEART Study: comparison between valsartan and amlodipine regarding morbidity and mortality in patients with hypertension and glucose intolerance.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Diabetes Complications; Humans; Hypertension; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan | 2010 |
Combined therapy with renin-angiotensin system and calcium channel blockers in type 2 diabetic hypertensive patients with proteinuria: effects on soluble TWEAK, PTX3, and flow-mediated dilation.
Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; C-Reactive Protein; Calcium Channel Blockers; Chi-Square Distribution; Cytokine TWEAK; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Renin-Angiotensin System; Serum Amyloid P-Component; Tetrazoles; Time Factors; Treatment Outcome; Tumor Necrosis Factors; Turkey; Valine; Valsartan; Vasodilation | 2010 |
Sex differences in effects of valsartan administration on cardiovascular outcomes in hypertensive patients: findings from the Jikei Heart Study.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Cardiovascular Diseases; Female; Humans; Hypertension; Male; Middle Aged; Risk Reduction Behavior; Sex Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Efficacy and safety of a single-pill combination of amlodipine/valsartan in Asian hypertensive patients inadequately controlled with amlodipine monotherapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Amlodipine; Antihypertensive Agents; Asian People; Double-Blind Method; Drug Combinations; Drug Resistance; Female; Humans; Hypertension; Male; Middle Aged; Tablets; Tetrazoles; Treatment Outcome; Valine; Valsartan; Young Adult | 2010 |
Effects of combined therapy of Xuezhikang Capsule and Valsartan on hypertensive left ventricular hypertrophy and heart rate turbulence.
Topics: Administration, Oral; Aged; Antihypertensive Agents; Arrhythmias, Cardiac; Capsules; Combined Modality Therapy; Drug Combinations; Drugs, Chinese Herbal; Female; Heart Rate; Humans; Hypertension; Hypertrophy, Left Ventricular; Hypolipidemic Agents; Integrative Medicine; Male; Medicine, Chinese Traditional; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Comparison of the effects of three angiotensin II receptor type 1 blockers on metabolic parameters in hypertensive patients with type 2 diabetes mellitus.
Topics: Adiponectin; Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Glucose; Blood Pressure; C-Reactive Protein; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Glycated Hemoglobin; Humans; Hypertension; Insulin Resistance; Lipids; Male; Middle Aged; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Angiotensin receptor blocker/diuretic combination preserves insulin responses in obese hypertensives.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Blood Glucose; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Diuretics; Drug Therapy, Combination; Female; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypertension; Insulin; Male; Middle Aged; Obesity; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Comparison of continuous positive airway pressure and valsartan in hypertensive patients with sleep apnea.
Topics: Angiotensin II Type 1 Receptor Blockers; Comorbidity; Continuous Positive Airway Pressure; Cross-Over Studies; Female; Humans; Hypertension; Intention to Treat Analysis; Male; Middle Aged; Sleep Apnea, Obstructive; Tetrazoles; Valine; Valsartan | 2010 |
Target blood pressure for treatment of isolated systolic hypertension in the elderly: valsartan in elderly isolated systolic hypertension study.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Heart Rate; Humans; Hypertension; Male; Medical History Taking; Patient Selection; Proportional Hazards Models; Reference Values; Stroke; Systole; Tetrazoles; Valine; Valsartan | 2010 |
Effect of high-dose valsartan on inflammatory and lipid parameters in patients with Type 2 diabetes and hypertension.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; C-Reactive Protein; Cholesterol; Cholesterol, LDL; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Interleukin-6; Lipids; Male; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan | 2010 |
Use of automated blood pressure measurements in clinical trials and registration studies: data from the VALTOP Study.
Topics: Adult; Automation; Blood Pressure Determination; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Observer Variation; Reproducibility of Results; Sphygmomanometers; Tetrazoles; Valine; Valsartan | 2010 |
Is the reno-protective effect of valsartan dose dependent? A comparative study of 80 and 160 mg day(-1).
Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; beta 2-Microglobulin; Blood Pressure; Blood Urea Nitrogen; Collagen Type IV; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2010 |
Comparison of the effects of nebivolol and valsartan on BP reduction and sleep apnoea activity in patients with essential hypertension and OSA.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II Type 1 Receptor Blockers; Benzopyrans; Blood Pressure; Ethanolamines; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nebivolol; Polysomnography; Sleep Apnea Syndromes; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Gender-specific, multi-level determinants of outcomes of antihypertensive treatment: a sub-analysis of the Belgian PREVIEW study.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Belgium; Blood Pressure; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patients; Physicians; Prospective Studies; Sex Characteristics; Tetrazoles; Treatment Failure; Treatment Outcome; Valine; Valsartan | 2011 |
Chronotherapy with valsartan/amlodipine fixed combination: improved blood pressure control of essential hypertension with bedtime dosing.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circadian Rhythm; Drug Chronotherapy; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Sleep; Tetrazoles; Valine; Valsartan | 2010 |
Time to achieve blood pressure goal with a combination versus a conventional monotherapy approach in hypertensive patients with metabolic syndrome.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Comorbidity; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Metabolic Syndrome; Middle Aged; Prospective Studies; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2010 |
Angiotensin II receptor blockade with valsartan decreases plasma osteopontin levels in patients with essential hypertension.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; C-Reactive Protein; Female; Humans; Hypertension; Male; Middle Aged; Osteopontin; Tetrazoles; Valine; Valsartan | 2011 |
Effectiveness and safety of high-dose valsartan monotherapy in hypertension treatment: the ValTop study.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Strong suppression of the renin-angiotensin system has a renal-protective effect in hypertensive patients: high-dose ARB with ACE inhibitor (Hawaii) study.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Chronic Disease; Drug Therapy, Combination; Female; Hawaii; Humans; Hypertension; Imidazoles; Imidazolidines; Kidney; Kidney Diseases; Male; Middle Aged; Proteinuria; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2010 |
Evaluation of pharmacokinetic interactions between amlodipine, valsartan, and hydrochlorothiazide in patients with hypertension.
Topics: Adolescent; Adult; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2011 |
Serial measurement of growth-differentiation factor-15 in heart failure: relation to disease severity and prognosis in the Valsartan Heart Failure Trial.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Atrial Fibrillation; Biomarkers; Diabetic Angiopathies; Female; Growth Differentiation Factor 15; Heart Failure; Humans; Hypertension; Male; Middle Aged; Placebos; Prognosis; Regression Analysis; Risk Assessment; Risk Factors; Severity of Illness Index; Tetrazoles; Valine; Valsartan | 2010 |
Triple combination therapy with amlodipine, valsartan, and hydrochlorothiazide vs dual combination therapy with amlodipine and hydrochlorothiazide for stage 2 hypertensive patients.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Effects of valsartan and amlodipine on cardiorenal protection in Japanese hypertensive patients: the Valsartan Amlodipine Randomized Trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Asian People; Blood Pressure; Cardiovascular Diseases; Female; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
Combination angiotensin receptor blocker-neutral endopeptidase inhibitor provides additive blood pressure reduction over angiotensin receptor blocker alone.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Neprilysin; Pyridines; Renin-Angiotensin System; Tetrazoles; Thiazepines; Valsartan | 2010 |
Moderate versus intensive treatment of hypertension with amlodipine/valsartan for patients uncontrolled on angiotensin receptor blocker monotherapy.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Tetrazoles; Valine; Valsartan | 2011 |
24-Hour ambulatory blood pressure response to combination valsartan/hydrochlorothiazide and amlodipine/hydrochlorothiazide in stage 2 hypertension by ethnicity: the EVALUATE study.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Combinations; Ethnicity; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Racial Groups; Regression Analysis; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Long-term safety and efficacy of aliskiren and valsartan combination with or without the addition of HCT in patients with hypertension.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Amides; Antihypertensive Agents; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Follow-Up Studies; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Incidence; Male; Middle Aged; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan; Young Adult | 2010 |
Comparison of the antihypertensive efficacy of irbesartan/HCTZ and valsartan/HCTZ combination therapy: impact of age and gender.
Topics: Adolescent; Adult; Age Factors; Aged; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Prospective Studies; Sex Characteristics; Tetrazoles; Treatment Outcome; Valine; Valsartan; Young Adult | 2010 |
Evaluation of dosing time-related anti-hypertensive efficacy of valsartan in patients with type 2 diabetes.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Diabetic Nephropathies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2011 |
Optimising management of hypertension in primary care: the Valsartan Intensified Primary Care Reduction of Blood Pressure (Viper-Bp) study.
Topics: Blood Pressure; Cohort Studies; Data Collection; Disease Management; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Pilot Projects; Primary Health Care; Tetrazoles; Valine; Valsartan | 2011 |
Real-life safety and effectiveness of amlodipine/valsartan combination in the treatment of hypertension.
Topics: Administration, Oral; Amlodipine; Antihypertensive Agents; Bangladesh; Blood Pressure; Blood Pressure Monitoring, Ambulatory; China; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Egypt; Female; Heart Rate; Humans; Hypertension; Malaysia; Male; Middle Aged; Pakistan; Product Surveillance, Postmarketing; Russia; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
24-Hour ambulatory blood pressure control with triple-therapy amlodipine, valsartan and hydrochlorothiazide in patients with moderate to severe hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2011 |
Suppressive effects of valsartan on microalbuminuria and CRP in patients with metabolic syndrome (Val-Mets).
Topics: Aged; Aged, 80 and over; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; C-Reactive Protein; Diabetes Complications; Female; Humans; Hypertension; Male; Metabolic Syndrome; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan | 2011 |
Effects of the angiotensin receptor blocker azilsartan medoxomil versus olmesartan and valsartan on ambulatory and clinic blood pressure in patients with stages 1 and 2 hypertension.
Topics: Adult; Aged; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Oxadiazoles; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
Beneficial cardiometabolic actions of telmisartan plus amlodipine therapy in elderly patients with poorly controlled hypertension.
Topics: Adiponectin; Age Factors; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Drug Substitution; Drug Therapy, Combination; Female; Humans; Hypertension; Japan; Male; Prospective Studies; Telmisartan; Tetrazoles; Time Factors; Treatment Outcome; Up-Regulation; Valine; Valsartan | 2011 |
Enhanced cardiovascular protective effects of valsartan in high-risk hypertensive patients with left ventricular hypertrophy--sub-analysis of the KYOTO HEART study.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Electrocardiography; Female; Follow-Up Studies; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Risk Factors; Tetrazoles; Valine; Valsartan | 2011 |
Efficacy and tolerability of a single-pill combination of amlodipine/valsartan in Asian hypertensive patients not adequately controlled with valsartan monotherapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Asian People; Calcium Channel Blockers; China; Double-Blind Method; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hypertension; Korea; Male; Middle Aged; Tetrazoles; Thailand; Treatment Outcome; Valine; Valsartan; Young Adult | 2011 |
Rationale and design of the Newer Versus Older Antihypertensive Agents in African Hypertensive Patients (NOAAH) trial.
Topics: Adult; Africa South of the Sahara; Aged; Amlodipine; Antihypertensive Agents; Bisoprolol; Black People; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diuretics; Drug Combinations; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Research Design; Risk Factors; Tetrazoles; Valine; Valsartan | 2011 |
Effectiveness and safety of valsartan in children aged 6 to 16 years with hypertension.
Topics: Adolescent; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Child; Dose-Response Relationship, Drug; Double-Blind Method; Female; Headache; Humans; Hypertension; Incidence; Longitudinal Studies; Male; Prospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
[Antihypertensive and nephroprotective effectiveness of AT1-angiotensin II receptor blocker valsartan in average therapeutic and maximal daily dose in patients with arterial hypertension and chronic kidney disease].
Topics: Administration, Oral; Aged; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Chronic Disease; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Hypertension; Kidney; Kidney Diseases; Male; Middle Aged; Receptor, Angiotensin, Type 1; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan; Vascular Resistance | 2011 |
Telmisartan reduces neointima volume and pulse wave velocity 8 months after zotarolimus-eluting stent implantation in hypertensive type 2 diabetic patients.
Topics: Adiponectin; Aged; Ankle Brachial Index; Anti-Inflammatory Agents; Benzimidazoles; Benzoates; C-Reactive Protein; Coronary Stenosis; Diabetes Mellitus, Type 2; Disease Progression; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Hypertension; Interleukin-6; Male; Middle Aged; Neointima; Prospective Studies; Single-Blind Method; Sirolimus; Telmisartan; Tetrazoles; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha; Ultrasonography, Interventional; Valine; Valsartan | 2011 |
Influence of telmisartan on insulin response after glucose loading in obese patients with hypertension: ARB trial of hypertension in obese patients with hyperinsulinemia assessed by oral glucose tolerance test (ATHLETE).
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Glucose; Blood Pressure; Female; Glucose; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypertension; Insulin Resistance; Male; Obesity; Telmisartan; Tetrazoles; Valine; Valsartan | 2011 |
Effect of valsartan, hydrochlorothiazide, and their combination on 24-h ambulatory blood pressure response in elderly patients with systolic hypertension: a ValVET substudy.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Tetrazoles; Valine; Valsartan | 2011 |
Comparison of the novel angiotensin II receptor blocker azilsartan medoxomil vs valsartan by ambulatory blood pressure monitoring.
Topics: Age Factors; Aged; Antihypertensive Agents; Benzimidazoles; Biological Availability; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dose-Response Relationship, Drug; Double-Blind Method; Drug Monitoring; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hypertension; Male; Middle Aged; Oxadiazoles; Sex Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
Moderate dietary sodium restriction added to angiotensin converting enzyme inhibition compared with dual blockade in lowering proteinuria and blood pressure: randomised controlled trial.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Chronic Disease; Combined Modality Therapy; Cross-Over Studies; Diet, Sodium-Restricted; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Kidney Diseases; Lisinopril; Male; Middle Aged; Patient Compliance; Proteinuria; Sodium Chloride, Dietary; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
Combination angiotensin-receptor blocker (ARB)/calcium channel blocker with HCTZ vs the maximal recommended dose of an ARB with HCTZ in patients with stage 2 hypertension: the exforge as compared to losartan treatment in stage 2 systolic hypertension (EXA
Topics: Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Treatment Outcome; United States; Valine; Valsartan | 2011 |
Chronotherapy with valsartan/hydrochlorothiazide combination in essential hypertension: improved sleep-time blood pressure control with bedtime dosing.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Sleep; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
Varying patterns of the antihypertensive and antialbuminuric response to higher doses of renin-angiotensin-aldosterone system blockade in albuminuric hypertensive type 2 diabetes mellitus patients.
Topics: Aged; Albuminuria; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2011 |
[Efficacy of fixed combination amlodipine/valsartan in hospitalized patients with hypertensive disease].
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Drug Monitoring; Drug Synergism; Female; Humans; Hypertension; Inpatients; Male; Medication Adherence; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
Treating systolic hypertension in the very elderly with valsartan-hydrochlorothiazide vs. either monotherapy: ValVET primary results.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Systole; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
Office and ambulatory blood pressure-lowering effects of combination valsartan/hydrochlorothiazide vs. hydrochlorothiazide-based therapy in obese, hypertensive patients.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Comorbidity; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Obesity; Office Visits; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
The efficacy and safety of valsartan in obese and non-obese pediatric hypertensive patients.
Topics: Adolescent; Antihypertensive Agents; Blood Pressure; Child; Comorbidity; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; International Cooperation; Male; Obesity; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
[Comparative effects of nebivolol and valsartan on atrial electromechanical coupling in newly diagnosed stage 1 hypertensive patients].
Topics: Antihypertensive Agents; Atrial Fibrillation; Benzopyrans; Echocardiography, Doppler; Ethanolamines; Female; Humans; Hypertension; Male; Middle Aged; Nebivolol; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
Effects of valsartan and amlodipine on home blood pressure and cardiovascular events in Japanese hypertensive patients: a subanalysis of the VART.
Topics: Aged; Albuminuria; Amlodipine; Angina Pectoris; Antihypertensive Agents; Asian People; Blood Pressure; Cardiovascular Diseases; Cause of Death; Creatinine; Death, Sudden; Female; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Kidney Failure, Chronic; Male; Middle Aged; Myocardial Infarction; Stroke; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2012 |
Combination effect of calcium channel blocker and valsartan on cardiovascular event prevention in patients with high-risk hypertension: ancillary results of the KYOTO HEART Study.
Topics: Aged; Angina Pectoris; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Female; Heart Failure; Humans; Hypertension; Japan; Male; Middle Aged; Myocardial Infarction; Risk Factors; Stroke; Tetrazoles; Valine; Valsartan | 2012 |
Efficacy and safety of valsartan compared to enalapril in hypertensive children: a 12-week, randomized, double-blind, parallel-group study.
Topics: Adolescent; Antihypertensive Agents; Blood Pressure; Child; Drug-Related Side Effects and Adverse Reactions; Enalapril; Female; Humans; Hypertension; Male; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
[Effects of benazepril and valsartan on erythropoietin levels in patients with essential hypertension].
Topics: Adult; Aged; Aged, 80 and over; Benzazepines; Erythropoietin; Female; Hemoglobins; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2011 |
Distinct effects of fixed combinations of valsartan with either amlodipine or hydrochlorothiazide on lipoprotein subfraction profile in patients with hypertension.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Cholesterol; Female; Humans; Hydrochlorothiazide; Hypertension; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Particle Size; Tetrazoles; Triglycerides; Valine; Valsartan | 2013 |
[Comparative efficacy of original and generic valsartan arterial hypertension].
Topics: Antihypertensive Agents; Blood Pressure; Drug Monitoring; Drugs, Generic; Female; Humans; Hypertension; Male; Middle Aged; Risk Factors; Severity of Illness Index; Single-Blind Method; Tetrazoles; Therapeutic Equivalency; Treatment Outcome; Valine; Valsartan | 2011 |
Comparing antihypertensive effect and plasma ciclosporin concentration between amlodipine and valsartan regimens in hypertensive renal transplant patients receiving ciclosporin therapy.
Topics: Adult; Amlodipine; Antihypertensive Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Pressure; Cyclosporine; Cytochrome P-450 CYP3A; Double-Blind Method; Drug Interactions; Female; Genotype; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Male; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prospective Studies; Tetrazoles; Valine; Valsartan | 2011 |
Ambulatory blood pressure response to triple therapy with an angiotensin-receptor blocker (ARB), calcium-channel blocker (CCB), and HCTZ versus dual therapy with an ARB and HCTZ.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2011 |
Comparison between valsartan and amlodipine regarding cardiovascular morbidity and mortality in hypertensive patients with glucose intolerance: NAGOYA HEART Study.
Topics: Amlodipine; Antihypertensive Agents; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glucose Intolerance; Glycated Hemoglobin; Humans; Hypertension; Japan; Male; Middle Aged; Morbidity; Prospective Studies; Risk Factors; Survival Rate; Tetrazoles; Valine; Valsartan | 2012 |
Antihypertensive and metabolic effects of Angiotensin receptor blocker/diuretic combination therapy in obese, hypertensive African American and white patients.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Black or African American; Blood Glucose; Diuretics; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hyperglycemia; Hypertension; Insulin; Intention to Treat Analysis; Male; Middle Aged; Obesity, Abdominal; Prediabetic State; Tetrazoles; Treatment Outcome; Valine; Valsartan; White People | 2013 |
Effect of switching from telmisartan, valsartan, olmesartan, or losartan to candesartan on morning hypertension.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Asian People; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Female; Humans; Hypertension; Imidazoles; Japan; Losartan; Male; Middle Aged; Prospective Studies; Telmisartan; Tetrazoles; Valine; Valsartan | 2012 |
Antihypertensive response to thiazide diuretic or angiotensin receptor blocker in elderly hypertensives is not influenced by pretreatment plasma renin activity.
Topics: Age Factors; Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Renin; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan | 2012 |
Cardio-cerebrovascular protective effects of valsartan in high-risk hypertensive patients with coronary artery disease (from the Kyoto Heart Study).
Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Coronary Artery Disease; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Incidence; Japan; Male; Prospective Studies; Risk Factors; Stroke; Survival Rate; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2012 |
Efficacy and safety of valsartan in hypertensive Taiwanese patients: post-marketing surveillance study.
Topics: Aged; Antihypertensive Agents; Asian People; Blood Pressure; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hypertension; Male; Middle Aged; Product Surveillance, Postmarketing; Taiwan; Tetrazoles; Valine; Valsartan | 2011 |
Effects of valsartan versus olmesartan addition to amlodipine/hydrochlorothiazide combination in treating stage 2 hypertensive patients.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2012 |
[Series: Clinical study from Japan and its reflections; KYOTO HEART study].
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Humans; Hypertension; Japan; Prospective Studies; Research Design; Tetrazoles; Valine; Valsartan | 2012 |
Effects of valsartan on fibrinolysis in hypertensive patients with metabolic syndrome.
Topics: Adipocytes; Adiponectin; Aged; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta; Apolipoproteins E; Biomarkers; Cardiovascular Diseases; Disease Models, Animal; Female; Fibrinolysis; Humans; Hypertension; Japan; Male; Metabolic Syndrome; Mice; Mice, Knockout; Middle Aged; Plasminogen Activator Inhibitor 1; Prospective Studies; Receptor, Angiotensin, Type 1; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2012 |
[Effects of valsartan combined with amlodipine or hydrochlorothiazide regimen on blood pressure variation in elderly hypertensive patients].
Topics: Aged; Amlodipine; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2012 |
Effects of valsartan or ramipril addition to amlodipine/hydrochlorothiazide combination on left ventricular mass in diabetic hypertensive patients with left ventricular hypertrophy.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Ramipril; Tetrazoles; Valine; Valsartan | 2012 |
Effects of exercise therapy alone and in combination with a calcium channel blocker or an angiotensin receptor blocker in hypertensive patients.
Topics: Adult; Aged; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Exercise Therapy; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2012 |
The effects of telmisartan treatment on the abdominal fat depot in patients with metabolic syndrome and essential hypertension: Abdominal fat Depot Intervention Program of Okayama (ADIPO).
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Glucose; Blood Pressure; Body Mass Index; Body Weight; Female; Humans; Hypertension; Insulin Resistance; Intra-Abdominal Fat; Male; Metabolic Syndrome; Middle Aged; PPAR gamma; Subcutaneous Fat; Telmisartan; Tetrazoles; Tomography, X-Ray Computed; Treatment Outcome; Valine; Valsartan; Waist Circumference | 2013 |
Amlodipine/valsartan 5/160 mg versus valsartan 160 mg in Chinese hypertensives.
Topics: Adult; Aged; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Asian People; Blood Pressure; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2013 |
Relationship between the receptor occupancy profile and pleiotropic effects of angiotensin II receptor blockers.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Area Under Curve; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Dinoprost; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Humans; Hypertension; Insulin; Insulin Resistance; Irbesartan; Luminescent Measurements; Male; Middle Aged; Oxidative Stress; Radioligand Assay; Receptors, Angiotensin; Tetrazoles; Time Factors; Valine; Valsartan; Young Adult | 2013 |
Comparison of the efficacy and safety profiles of two fixed-dose combinations of antihypertensive agents, amlodipine/benazepril versus valsartan/hydrochlorothiazide, in patients with type 2 diabetes mellitus and hypertension: a 16-week, multicenter, rando
Topics: Aged; Albuminuria; Amlodipine; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Biomarkers; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; Drug Combinations; Female; Glycated Hemoglobin; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Prospective Studies; Taiwan; Tetrazoles; Time Factors; Treatment Outcome; Uric Acid; Valine; Valsartan | 2012 |
Post-marketing surveillance study of valsartan/amlodipine combination in Taiwanese hypertensive patients.
Topics: Aged; Amlodipine; Antihypertensive Agents; Asian People; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Product Surveillance, Postmarketing; Prospective Studies; Taiwan; Tetrazoles; Time Factors; Valine; Valsartan | 2012 |
The effect of valsartan versus non-RAAS treatment on autoregulation of cerebral blood flow.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cerebrovascular Circulation; Female; Humans; Hypertension; Male; Middle Aged; Pulse Wave Analysis; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2012 |
Efficacy and safety of valsartan in reducing blood pressure and albuminuria in Chinese patients with essential hypertension: a multicenter prospective open-label observational study.
Topics: Aged; Albuminuria; Antihypertensive Agents; Asian People; Blood Pressure; China; Diabetes Complications; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan | 2012 |
Cardiovascular outcomes in hypertensive patients: comparing single-agent therapy with combination therapy.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Prognosis; Retrospective Studies; Stroke; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2012 |
Changes in aortic pulse wave velocity in hypertensive postmenopausal women: comparison between a calcium channel blocker vs angiotensin receptor blocker regimen.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Postmenopause; Pulse Wave Analysis; Tetrazoles; Valine; Valsartan; Vascular Stiffness | 2012 |
Efficacy of aliskiren and valsartan in hypertensive patients with albuminuria: a randomized parallel-group study.
Topics: Albuminuria; Amides; Antihypertensive Agents; Demography; Female; Fumarates; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Pulse Wave Analysis; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2013 |
Improved blood pressure control with nifedipine GITS/valsartan combination versus high-dose valsartan monotherapy in mild-to-moderate hypertensive patients from Asia: results from the ADVISE study, a randomized trial.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Asian People; Blood Pressure; Comorbidity; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Prospective Studies; Tetrazoles; Valine; Valsartan; Young Adult | 2012 |
Aliskiren reduces home blood pressure and albuminuria in patients with hypertensive nephrosclerosis.
Topics: Adult; Aged; Albuminuria; Amides; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Female; Fumarates; Humans; Hypertension; Hypertension, Renal; Male; Middle Aged; Nephritis; Nephrosclerosis; Tetrazoles; Valine; Valsartan | 2013 |
The comparative effects of valsartan and amlodipine on vascular microinflammation in newly diagnosed hypertensive patients.
Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; C-Reactive Protein; Calcium Channel Blockers; Female; Humans; Hypertension; Inflammation Mediators; Male; Middle Aged; Prospective Studies; Risk Factors; Serum Amyloid P-Component; Tetrazoles; Valine; Valsartan; Vasculitis | 2013 |
Effects of valsartan on progression of kidney disease in Japanese hypertensive patients with advanced, predialysis, chronic kidney disease: Kanagawa Valsartan Trial (KVT).
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Asian People; Blood Pressure; Comorbidity; Creatinine; Disease Progression; Female; Humans; Hypertension; Japan; Male; Middle Aged; Proteinuria; Renal Insufficiency, Chronic; Renal Replacement Therapy; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2013 |
An additional LDL-lowering effect of amlodipine; not only an antihypertensive?
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Cholesterol; Dyslipidemias; Essential Hypertension; Female; Humans; Hypertension; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Tetrazoles; Triglycerides; Valine; Valsartan | 2013 |
Effect of valsartan with bedtime dosing on chronic kidney disease patients with nondipping blood pressure pattern.
Topics: Adult; Analysis of Variance; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Chi-Square Distribution; Drug Chronotherapy; Echocardiography; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2013 |
The comparative effects of valsartan and amlodipine on vWf levels and N/L ratio in patients with newly diagnosed hypertension.
Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; Calcium Channel Blockers; Essential Hypertension; Female; Humans; Hypertension; Leukocyte Count; Lymphocytes; Male; Middle Aged; Neutrophils; Prospective Studies; Tetrazoles; Valine; Valsartan; von Willebrand Factor | 2013 |
Amlodipine seems to be superior to valsartan in decreasing microalbuminuria in newly diagnosed hypertensive patients: a novel effect to be explained with hyperfiltration?
Topics: Adult; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2013 |
Comparative effect of candesartan and amlodipine, and effect of switching from valsartan, losartan, telmisartan and olmesartan to candesartan, on early morning hypertension and heart rate.
Topics: Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Drug Substitution; Female; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Prospective Studies; Telmisartan; Tetrazoles; Valine; Valsartan | 2013 |
Randomized study of antihypertensive efficacy and safety of combination aliskiren/valsartan vs valsartan monotherapy in hypertensive participants with type 2 diabetes mellitus.
Topics: Aged; Amides; Antihypertensive Agents; Blood Pressure; Blood Urea Nitrogen; Comorbidity; Creatinine; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Humans; Hypertension; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2013 |
Efficacy of eplerenone added to renin-angiotensin blockade in hypertensive patients.
Topics: Abdominal Pain; Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Eplerenone; Female; Headache; Heart Rate; Humans; Hypertension; Irbesartan; Losartan; Male; Middle Aged; Patient Dropouts; Renin-Angiotensin System; Spironolactone; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2002 |
Microalbuminuria reduction with valsartan in patients with type 2 diabetes mellitus: a blood pressure-independent effect.
Topics: Adult; Aged; Albuminuria; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2002 |
[Efficacy and tolerance of ACE inhibitor invoril and angiotensin I At-receptor blocker diovan in patients with stages I-II of arterial hypertension].
Topics: Adult; Aged; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Drug Tolerance; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Valine; Valsartan | 2002 |
Influence of AT1 receptor blockade on blood pressure, renal haemodynamics and hormonal responses to intravenous angiotensin II infusion in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Losartan; Male; Middle Aged; Receptor, Angiotensin, Type 1; Renal Circulation; Renin; Tetrazoles; Valine; Valsartan | 2002 |
AT1-receptor blockade improves augmentation index: a double-blind, randomized, controlled study.
Topics: Adult; Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Aorta; Blood Pressure; Diastole; Diuretics; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pulse; Radial Artery; Receptor, Angiotensin, Type 1; Sodium Chloride Symporter Inhibitors; Systole; Tetrazoles; Valine; Valsartan | 2002 |
[Tolerance to valsartan in office practice in 3,197 hypertensive patients (the VALSE study)].
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Female; Humans; Hypertension; Male; Middle Aged; Office Visits; Prospective Studies; Tetrazoles; Valine; Valsartan | 2000 |
Effect of AT1 receptor blockade on endothelial function in essential hypertension.
Topics: Acetylcholine; Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Cohort Studies; Diuretics; Double-Blind Method; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; omega-N-Methylarginine; Receptor, Angiotensin, Type 1; Regional Blood Flow; Rest; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan; Vasodilator Agents | 2003 |
[Control of systolic blood pressure in the VALUE trial after 12 months].
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Double-Blind Method; Europe; Female; Germany; Humans; Hypertension; Male; Middle Aged; Prognosis; Reference Standards; Risk Factors; Tetrazoles; Valine; Valsartan | 2003 |
[Lowering of blood pressure, blood pressure amplitude and heart rate by treatment with valsartan or valsartan/hydrochlorothiazide. Results of an open observation study of 11,447 hypertensives].
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Safety; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan | 2003 |
Effects of valsartan with or without benazepril on blood pressure, angiotensin II, and endoxin in patients with essential hypertension.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure; Cardenolides; Digoxin; Female; Humans; Hypertension; Male; Middle Aged; Saponins; Tetrazoles; Valine; Valsartan | 2003 |
Valsartan/hydrochlorothiazide is effective in hypertensive patients inadequately controlled by valsartan monotherapy.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Diuretics; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan | 2003 |
The Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial in Slovakia.
Topics: Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Antihypertensive Agents; Cardiovascular Diseases; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Risk Factors; Slovakia; Tetrazoles; Valine; Valsartan | 2003 |
VALUE trial: Long-term blood pressure trends in 13,449 patients with hypertension and high cardiovascular risk.
Topics: Algorithms; Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Cohort Studies; Double-Blind Method; Drug Utilization; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Risk; Tetrazoles; Valine; Valsartan | 2003 |
[Efficiency of diovan (valsartane) in arterial hypertension patients].
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Endopeptidases; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2003 |
Administration time-dependent effects of valsartan on ambulatory blood pressure in hypertensive subjects.
Topics: Adult; Antihypertensive Agents; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Diastole; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Systole; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2003 |
Sexual activity in hypertensive men.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Coitus; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Sexual Behavior; Sodium Chloride Symporter Inhibitors; Surveys and Questionnaires; Tetrazoles; Valine; Valsartan | 2003 |
Efficacy of various antihypertensive agents as evaluated by indices of vascular stiffness in elderly hypertensive patients.
Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Ankle; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brachial Artery; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Male; Nifedipine; Pulsatile Flow; Tetrazoles; Thiazepines; Treatment Outcome; Valine; Valsartan | 2003 |
Direct comparison of the effects of valsartan and amlodipine on renal hemodynamics in human essential hypertension.
Topics: Amlodipine; Antihypertensive Agents; Double-Blind Method; Glomerular Filtration Rate; Humans; Hypertension; Microcirculation; Middle Aged; Renal Circulation; Tetrazoles; Valine; Valsartan | 2003 |
A randomized, double-blind, active-controlled, parallel-group comparison of valsartan and amlodipine in the treatment of isolated systolic hypertension in elderly patients: the Val-Syst study.
Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Sodium Chloride Symporter Inhibitors; Systole; Tetrazoles; Valine; Valsartan | 2003 |
Effect of valsartan and atenolol on sexual behavior in hypertensive postmenopausal women.
Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Atenolol; Blood Pressure; Female; Hormone Replacement Therapy; Humans; Hypertension; Libido; Middle Aged; Postmenopause; Sexual Behavior; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
Effects of valsartan compared with enalapril on blood pressure and cognitive function in elderly patients with essential hypertension.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cognition; Enalapril; Female; Humans; Hypertension; Male; Memory; Tetrazoles; Valine; Valsartan | 2004 |
Comparison of valsartan and amlodipine on ambulatory and morning blood pressure in hypertensive patients.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Chronotherapy; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
Effect of the angiotensin II antagonist valsartan on sexual function in hypertensive men.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II; Antihypertensive Agents; Blood Pressure; Erectile Dysfunction; Humans; Hypertension; Male; Middle Aged; Orgasm; Patient Satisfaction; Penile Erection; Sexual Behavior; Surveys and Questionnaires; Tetrazoles; Valine; Valsartan | 2003 |
Efficacy and tolerability of the combination valsartan/hydrochlorothiazide compared with amlodipine in a mild-to-moderately hypertensive Brazilian population.
Topics: Aged; Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brazil; Double-Blind Method; Drug Therapy, Combination; Edema; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Racial Groups; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2003 |
Effect of an angiotensin II type 1 receptor blocker, valsartan, on neurohumoral factors in patients with hypertension: comparison with a long-acting calcium channel antagonist, amlodipine.
Topics: Aged; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Coronary Disease; Delayed-Action Preparations; Female; Heart Failure; Humans; Hypertension; Male; Middle Aged; Natriuretic Peptide, Brain; Neurotransmitter Agents; Norepinephrine; Receptor, Angiotensin, Type 1; Tetrazoles; Time Factors; Valine; Valsartan | 2003 |
Effects of the angiotensin II receptor blockers telmisartan versus valsartan on the circadian variation of blood pressure: impact on the early morning period.
Topics: Adult; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Canada; Circadian Rhythm; Cross-Over Studies; Diastole; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Receptors, Angiotensin; Systole; Telmisartan; Tetrazoles; Treatment Outcome; United States; Valine; Valsartan | 2004 |
Comparison of the effects on 24-h ambulatory blood pressure of valsartan and amlodipine, alone or in combination with a low-dose diuretic, in elderly patients with isolated systolic hypertension (Val-syst Study).
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2004 |
Effects of telmisartan 80 mg and valsartan 160 mg on ambulatory blood pressure in patients with essential hypertension.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Tablets; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan; White People | 2004 |
Simvastatin reduces interleukin-1beta secretion by peripheral blood mononuclear cells in patients with essential hypertension.
Topics: Aged; Angiotensin II; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Hypertension; Inflammation; Interleukin-1; Leukocytes, Mononuclear; Lipids; Male; Middle Aged; Simvastatin; Tetrazoles; Valine; Valsartan | 2004 |
Effects of an angiotensin II receptor blocker, valsartan, on residual renal function in patients on CAPD.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Creatinine; Female; Humans; Hypertension; Japan; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Cavity; Peritoneal Dialysis, Continuous Ambulatory; Prospective Studies; Proteinuria; Retrospective Studies; Tetrazoles; Urine; Valine; Valsartan | 2004 |
Comparative effects of valsartan versus amlodipine on left ventricular mass and reactive oxygen species formation by monocytes in hypertensive patients with left ventricular hypertrophy.
Topics: Amlodipine; Antihypertensive Agents; Cross-Sectional Studies; Double-Blind Method; Echocardiography; Female; Flow Cytometry; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Monocytes; Prospective Studies; Reactive Oxygen Species; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Diuretics; Double-Blind Method; Endpoint Determination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Risk Factors; Sodium Chloride Symporter Inhibitors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
Comparison of valsartan 160 mg with lisinopril 20 mg, given as monotherapy or in combination with a diuretic, for the treatment of hypertension: the Blood Pressure Reduction and Tolerability of Valsartan in Comparison with Lisinopril (PREVAIL) study.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Chi-Square Distribution; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Italy; Lisinopril; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
Sustained antihypertensive activity of telmisartan compared with valsartan.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diastole; Double-Blind Method; Female; Half-Life; Humans; Hypertension; Male; Middle Aged; Placebos; Single-Blind Method; Systole; Telmisartan; Tetrazoles; Valine; Valsartan | 2004 |
Differential time effect profiles of amlodipine, as compared to valsartan, revealed by ambulatory blood pressure monitoring, self blood pressure measurements and dose omission protocol.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Time Factors; Valine; Valsartan | 2004 |
JIKEI HEART Study--a morbi-mortality and remodeling study with valsartan in Japanese patients with hypertension and cardiovascular disease.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Cardiovascular Diseases; Female; Follow-Up Studies; Heart Failure; Humans; Hypertension; Japan; Male; Middle Aged; Myocardial Ischemia; Quality of Life; Tetrazoles; Treatment Outcome; Valine; Valsartan; Ventricular Function, Left; Ventricular Remodeling | 2004 |
Ambulatory versus clinic blood pressure for the assessment of anti hypertensive efficacy in clinical trials: insights from the Val-Syst Study.
Topics: Aged; Aged, 80 and over; Ambulatory Care Facilities; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Male; Patient Selection; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
Effects of valsartan and nifedipine coat-core on systemic arterial stiffness in hypertensive patients.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arteries; Blood Flow Velocity; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
Use of 24-hour ambulatory blood pressure monitoring to assess antihypertensive efficacy: a comparison of olmesartan medoxomil, losartan potassium, valsartan, and irbesartan.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Double-Blind Method; Female; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Monitoring, Physiologic; Olmesartan Medoxomil; Single-Blind Method; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2005 |
Replacement of valsartan and candesartan by telmisartan in hypertensive patients with type 2 diabetes: metabolic and antiatherogenic consequences.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Hypertension; Male; Middle Aged; Telmisartan; Tetrazoles; Valine; Valsartan | 2005 |
Comparison of antihypertensive effects of an angiotensin-converting enzyme inhibitor, a calcium antagonist and a diuretic in patients with hypertension not controlled by angiotensin receptor blocker monotherapy.
Topics: Adolescent; Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chlorthalidone; Cross-Over Studies; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
24-hour ambulatory blood-pressure effects of valsartan and hydrochlorothiazide combinations compared with amlodipine in hypertensive patients at increased cardiovascular risk: a VAST sub-study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Risk Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
Valsartan reduces interleukin-1beta secretion by peripheral blood mononuclear cells in patients with essential hypertension.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Female; Humans; Hypertension; Interleukin-1; Leukocytes, Mononuclear; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2005 |
Renoprotective effect of early inhibition of the renin-angiotensin system in renal transplant recipients.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Creatinine; Enalapril; Follow-Up Studies; Humans; Hypertension; Kidney Function Tests; Kidney Transplantation; Losartan; Proteinuria; Ramipril; Renal Artery; Renin-Angiotensin System; Tetrazoles; Time Factors; Valine; Valsartan | 2005 |
Effect of valsartan on monocyte/endothelial cell activation markers and adiponectin in hypertensive patients with type 2 diabetes mellitus.
Topics: Aged; Biomarkers; Cytokines; Diabetes Mellitus, Type 2; Endothelial Cells; Female; Humans; Hypertension; Male; Middle Aged; Monocytes; Tetrazoles; Valine; Valsartan | 2006 |
Effects of valsartan and perindopril combination therapy on left ventricular hypertrophy and aortic arterial stiffness in patients with essential hypertension.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Ankle; Aorta; Blood Pressure Monitoring, Ambulatory; Drug Therapy, Combination; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Japan; Male; Middle Aged; Natriuretic Peptide, Brain; Perindopril; Prospective Studies; Pulse; Tetrazoles; Valine; Valsartan | 2005 |
Efficacy and tolerability of combination therapy with valsartan plus hydrochlorothiazide compared with amlodipine monotherapy in hypertensive patients with other cardiovascular risk factors: the VAST study.
Topics: Age Factors; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypercholesterolemia; Hypertension; Male; Middle Aged; Myocardial Infarction; Obesity; Risk Factors; Tetrazoles; Valine; Valsartan | 2005 |
Comparison of the effects of valsartan and felodipine on plasma leptin and insulin sensitivity in hypertensive obese patients.
Topics: Aged; Antihypertensive Agents; Felodipine; Female; Humans; Hypertension; Insulin Resistance; Leptin; Male; Middle Aged; Obesity; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
A comparison of valsartan and perindopril in the treatment of essential hypertension in the malaysian population.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Female; Follow-Up Studies; Humans; Hypertension; Malaysia; Male; Middle Aged; Perindopril; Prevalence; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
A noninferiority comparison of valsartan/hydrochlorothiazide combination versus amlodipine in black hypertensives.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Black People; Blood Pressure; Calcium Channel Blockers; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
Decrease in urinary albumin excretion associated with the normalization of nocturnal blood pressure in hypertensive subjects.
Topics: Adult; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Double-Blind Method; Drug Administration Schedule; Female; Fibrinogen; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan | 2005 |
Administration time-dependent effects of valsartan on ambulatory blood pressure in elderly hypertensive subjects.
Topics: Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Drug Administration Schedule; Female; Humans; Hypertension; Male; Prospective Studies; Tetrazoles; Valine; Valsartan | 2005 |
Treatment of non-dipper hypertension with bedtime administration of valsartan.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
Haemodynamic effects of eprosartan and valsartan in hypertensive patients during isometric and mental stress.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Female; Forearm; Hand Strength; Heart Rate; Humans; Hypertension; Imidazoles; Laser-Doppler Flowmetry; Male; Microcirculation; Middle Aged; Skin; Stress, Psychological; Tetrazoles; Thiophenes; Time Factors; Treatment Outcome; Valine; Valsartan | 2005 |
Antihypertensive efficacy and tolerability of two fixed-dose combinations of valsartan and hydrochlorothiazide compared with valsartan monotherapy in patients with stage 2 or 3 systolic hypertension: an 8-week, randomized, double-blind, parallel-group tri
Topics: Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Patient Compliance; Tetrazoles; Valine; Valsartan | 2005 |
Hemodynamic and metabolic responses to valsartan and atenolol in obese hypertensive patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Atenolol; Blood Glucose; Blood Pressure; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Obesity; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan | 2005 |
A home blood pressure monitoring study comparing the antihypertensive efficacy of two angiotensin II receptor antagonist fixed combinations.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Musculoskeletal Diseases; Prospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
Haemodynamic effects of AT1 inhibition and Ca2+-channel blockade in hypertensive patients during isometric stress.
Topics: Amlodipine; Analysis of Variance; Antihypertensive Agents; Calcium Channel Blockers; Cross-Over Studies; Double-Blind Method; Female; Forearm; Hand Strength; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Plethysmography; Tetrazoles; Valine; Valsartan; Vascular Resistance | 2006 |
Valsartan inhibits platelet activity at different doses in mild to moderate hypertensives: Valsartan Inhibits Platelets (VIP) trial.
Topics: Aged; Antihypertensive Agents; Blood Platelets; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; Male; Severity of Illness Index; Tetrazoles; Valine; Valsartan | 2006 |
[Valsartan in patients with arterial hypertension and type 2 diabetes mellitus. The lapaval study].
Topics: Adult; Aged; Antihypertensive Agents; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Humans; Hypertension; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan | 2005 |
Angiotensin II type 1 receptor blockers reduce urinary oxidative stress markers in hypertensive diabetic nephropathy.
Topics: Adult; Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Diabetic Nephropathies; Female; Humans; Hypertension; Male; Middle Aged; Oxidative Stress; Single-Blind Method; Tetrazoles; Trichlormethiazide; Valine; Valsartan | 2006 |
Selective angiotensin receptor antagonism with valsartan decreases arterial stiffness independently of blood pressure lowering in hypertensive patients.
Topics: Angiotensin II Type 1 Receptor Blockers; Arteries; Blood Pressure; Female; Hemodynamics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Male; Middle Aged; Plethysmography; Prospective Studies; Pulse; Tetrazoles; Valine; Valsartan | 2005 |
The angiotensin II receptor antagonist valsartan enhances lipoprotein lipase mass in preheparin serum in type 2 diabetes with hypertension.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Diabetes Mellitus, Type 2; Female; Humans; Hyperlipidemias; Hypertension; Lipoprotein Lipase; Lipoproteins; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2006 |
Valsartan, blood pressure reduction, and C-reactive protein: primary report of the Val-MARC trial.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; C-Reactive Protein; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Inflammation; Male; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan | 2006 |
The effect of oral glucose loads on tissue metabolism during angiotensin II receptor and beta-receptor blockade in obese hypertensive subjects.
Topics: Adipose Tissue; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Ethanol; Fatty Acids, Nonesterified; Female; Glucose; Glucose Tolerance Test; Glycerol; Humans; Hypertension; Insulin; Kinetics; Lactic Acid; Lipids; Male; Metabolism; Middle Aged; Muscle, Skeletal; Obesity; Tetrazoles; Valine; Valsartan | 2006 |
Angiotensin receptor blocker added to previous antihypertensive agents on arteries of diabetic hypertensive patients.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteries; Atenolol; Biopsy; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diastole; Female; Humans; Hypertension; Male; Middle Aged; Organ Culture Techniques; Subcutaneous Tissue; Systole; Tetrazoles; Time; Treatment Outcome; Valine; Valsartan | 2006 |
Effects of valsartan compared to amlodipine on preventing type 2 diabetes in high-risk hypertensive patients: the VALUE trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Risk Factors; Tetrazoles; Valine; Valsartan | 2006 |
Randomized, double-blind, crossover comparison of amlodipine and valsartan in african-americans with hypertension using 24-hour ambulatory blood pressure monitoring.
Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Black or African American; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypertension; Male; Tetrazoles; Valine; Valsartan | 2006 |
Effects of amlodipine and valsartan on vascular damage and ambulatory blood pressure in untreated hypertensive patients.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Carotid Arteries; Endothelium, Vascular; Female; Humans; Hypertension; Male; Middle Aged; Pulse; Tetrazoles; Valine; Valsartan; Vascular Resistance | 2006 |
Valsartan and retinal endothelial function in elderly hypertensive patients.
Topics: Aged; Aged, 80 and over; Blood Flow Velocity; Cholesterol, LDL; Endothelium, Vascular; Hemodynamics; Humans; Hypertension; Male; Middle Aged; omega-N-Methylarginine; Retinal Artery; Tetrazoles; Valine; Valsartan | 2006 |
The Valsartan Antihypertensive Long-Term Use Evaluation (VALUE) trial: outcomes in patients receiving monotherapy.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiac Output, Low; Diabetes Mellitus; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Incidence; Male; Middle Aged; Risk; Tetrazoles; Valine; Valsartan | 2006 |
Effects of the angiotensin II receptor blockers telmisartan vs valsartan in combination with hydrochlorothiazide 25 mg once daily for the treatment of hypertension.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Placebos; Telmisartan; Tetrazoles; United States; Valine; Valsartan | 2006 |
Targeting hypertension with valsartan: Lessons learned from the Valsartan/HCTZ versus Amlodipine in stage II hypertensive patients (VASt) trial.
Topics: Amlodipine; C-Reactive Protein; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Interleukin-6; Lipoproteins, LDL; Tetrazoles; Tissue Plasminogen Activator; Valine; Valsartan | 2006 |
Effect on blood pressure control of switching from valsartan monotherapy to losartan/hydrochlorothiazide in Asian patients with hypertension: results of a multicentre open-label trial.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Asian People; Blood Pressure; Drug Combinations; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan | 2006 |
Acute administration of a single dose of valsartan improves left ventricular functions: a pilot study to assess the role of tissue velocity echocardiography in patients with systemic arterial hypertension in the TVE-valsartan study I.
Topics: Adult; Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Dose-Response Relationship, Drug; Echocardiography, Doppler, Color; Female; Heart Rate; Humans; Hypertension; Image Processing, Computer-Assisted; Male; Middle Aged; Myocardial Contraction; Pilot Projects; Research Design; Stroke Volume; Sweden; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan; Ventricular Function, Left | 2006 |
Outcomes in subgroups of hypertensive patients treated with regimens based on valsartan and amlodipine: An analysis of findings from the VALUE trial.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Female; Heart Arrest; Heart Failure; Humans; Hypertension; Male; Middle Aged; Proportional Hazards Models; Sex Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2006 |
Additional antihypertensive effect of drugs in hypertensive subjects uncontrolled on diltiazem monotherapy: a randomized controlled trial using office and home blood pressure monitoring.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chlorthalidone; Diltiazem; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Office Visits; Sodium Chloride Symporter Inhibitors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2006 |
Effects of valsartan and indapamide on plasma cytokines in essential hypertension.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Chemokine CCL2; Chemokine CCL3; Chemokine CCL4; Cytokines; Diuretics; Female; Humans; Hypertension; Indapamide; Macrophage Inflammatory Proteins; Male; Middle Aged; P-Selectin; Tetrazoles; Valine; Valsartan | 2006 |
Efficacy and safety of valsartan, an angiotensin II receptor antagonist, in hypertension after renal transplantation: a randomized multicenter study.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Diastole; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Kidney Transplantation; Male; Middle Aged; Placebos; Postoperative Complications; Safety; Systole; Tetrazoles; Valine; Valsartan | 2006 |
Angiotensin type 2 receptor in resistance arteries of type 2 diabetic hypertensive patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arteries; Atenolol; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Receptor, Angiotensin, Type 2; Tetrazoles; Valine; Valsartan; Vascular Resistance; Vasodilation | 2007 |
Bradykinin B(2) receptor does not contribute to blood pressure lowering during AT(1) receptor blockade.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Bradykinin; Bradykinin B2 Receptor Antagonists; Cross-Over Studies; Cyclic GMP; Diet, Sodium-Restricted; Female; Heart Rate; Humans; Hypertension; Male; Receptor, Bradykinin B2; Renin; Sodium; Tetrazoles; Valine; Valsartan | 2007 |
Aliskiren, an orally effective renin inhibitor, provides antihypertensive efficacy alone and in combination with valsartan.
Topics: Adult; Aged; Amides; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2007 |
Effect of valsartan addition to amlodipine on ankle oedema and subcutaneous tissue pressure in hypertensive patients.
Topics: Adult; Age Factors; Aged; Amlodipine; Ankle; Blood Pressure; Cross-Over Studies; Drug Therapy, Combination; Edema; Female; Humans; Hypertension; Male; Middle Aged; Placebos; Prospective Studies; Single-Blind Method; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2007 |
Ambulatory blood pressure monitoring after 1 year on valsartan or amlodipine-based treatment: a VALUE substudy.
Topics: Age Factors; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Denmark; Female; Heart Rate; Humans; Hypertension; Italy; Male; Middle Aged; Office Visits; Randomized Controlled Trials as Topic; Reproducibility of Results; Research; Risk Factors; Tetrazoles; United States; Valine; Valsartan | 2007 |
Controlled release nifedipine and valsartan combination therapy in patients with essential hypertension: the adalat CR and valsartan cost-effectiveness combination (ADVANCE-combi) study.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cost-Benefit Analysis; Delayed-Action Preparations; Drug Costs; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2006 |
Effects of the angiotensin II type 1 receptor antagonist valsartan on the expression of superoxide dismutase in hypertensive patients.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Blotting, Northern; Dizziness; Double-Blind Method; Exanthema; Female; Gene Expression Regulation, Enzymologic; Humans; Hypertension; Male; Middle Aged; Patient Dropouts; RNA, Messenger; Superoxide Dismutase; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2007 |
Effects of valsartan or amlodipine alone or in combination on plasma catecholamine levels at rest and during standing in hypertensive patients.
Topics: Adolescent; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; Catecholamines; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Posture; Rest; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2007 |
Comparison of increasing doses of olmesartan medoxomil, losartan potassium, and valsartan in patients with essential hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Olmesartan Medoxomil; Severity of Illness Index; Single-Blind Method; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2007 |
Effect of antihypertensive agents on plasma adiponectin levels in hypertensive patients with metabolic syndrome.
Topics: Adiponectin; Adrenergic beta-Antagonists; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Doxazosin; Female; Humans; Hypertension; Insulin Resistance; Lipids; Male; Metabolic Syndrome; Metoprolol; Middle Aged; Predictive Value of Tests; Prospective Studies; Ramipril; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2007 |
Comparison of valsartan/hydrochlorothiazide combination therapy at doses up to 320/25 mg versus monotherapy: a double-blind, placebo-controlled study followed by long-term combination therapy in hypertensive adults.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2007 |
Valsartan in a Japanese population with hypertension and other cardiovascular disease (Jikei Heart Study): a randomised, open-label, blinded endpoint morbidity-mortality study.
Topics: Adult; Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Coronary Disease; Endpoint Determination; Female; Follow-Up Studies; Heart Failure; Humans; Hypertension; Japan; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2007 |
Tolerability and blood pressure-lowering efficacy of the combination of amlodipine plus valsartan compared with lisinopril plus hydrochlorothiazide in adult patients with stage 2 hypertension.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2007 |
Amlodipine and valsartan combined and as monotherapy in stage 2, elderly, and black hypertensive patients: subgroup analyses of 2 randomized, placebo-controlled studies.
Topics: Age Factors; Aged; Amlodipine; Antihypertensive Agents; Black People; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Research Design; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2007 |
Reduction of QTc dispersion by the angiotensin II receptor blocker valsartan may be related to its anti-oxidative stress effect in patients with essential hypertension.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Collagen Type I; Collagen Type III; Electrocardiography; Female; Follow-Up Studies; Heart Rate; Humans; Hypertension; Hypertrophy, Left Ventricular; Lipid Peroxidation; Long QT Syndrome; Male; Oxidative Stress; Prospective Studies; Tetrazoles; Valine; Valsartan | 2007 |
Effect of angiotensin receptor blockade and antihypertensive drugs on diastolic function in patients with hypertension and diastolic dysfunction: a randomised trial.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Echocardiography; Female; Heart Rate; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Renin-Angiotensin System; Stroke Volume; Tetrazoles; Valine; Valsartan | 2007 |
Two multicenter, 8-week, randomized, double-blind, placebo-controlled, parallel-group studies evaluating the efficacy and tolerability of amlodipine and valsartan in combination and as monotherapy in adult patients with mild to moderate essential hyperten
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Edema; Female; Headache; Humans; Hypertension; Male; Middle Aged; Nasopharyngitis; Tetrazoles; Valine; Valsartan | 2007 |
Effects of valsartan alone versus valsartan/simvastatin combination on ambulatory blood pressure, C-reactive protein, lipoproteins, and monocyte chemoattractant protein-1 in patients with hyperlipidemia and hypertension.
Topics: Antihypertensive Agents; Biomarkers; Blood Pressure Monitoring, Ambulatory; C-Reactive Protein; Chemokine CCL2; Double-Blind Method; Drug Combinations; Drug Synergism; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Lipoproteins; Male; Middle Aged; Simvastatin; Tetrazoles; Valine; Valsartan | 2007 |
Efficacy and safety of combined use of aliskiren and valsartan in patients with hypertension: a randomised, double-blind trial.
Topics: Amides; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Endpoint Determination; Female; Fumarates; Humans; Hypertension; Male; Middle Aged; Renin; Tetrazoles; Valine; Valsartan | 2007 |
Is renoprotection by angiotensin receptor blocker dependent on blood pressure?: the Saitama Medical School, Albuminuria Reduction in Diabetics with Valsartan (STAR) study.
Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Calcium Channel Blockers; Diabetic Nephropathies; Drug Therapy, Combination; Humans; Hypertension; Kidney; Middle Aged; Tetrazoles; Valine; Valsartan | 2007 |
Effect of fluvastatin and valsartan, alone and in combination, on postprandial vascular inflammation and fibrinolytic activity in patients with essential hypertension.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Dietary Fats; Double-Blind Method; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Female; Fibrinolysis; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Indoles; Lipids; Male; Middle Aged; P-Selectin; Plasminogen Activator Inhibitor 1; Postprandial Period; Tetrazoles; Tissue Plasminogen Activator; Valine; Valsartan; Vasculitis | 2007 |
Impact of new-onset diabetes mellitus on cardiac outcomes in the Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial population.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Diabetes Complications; Diabetic Angiopathies; Double-Blind Method; Drug Administration Schedule; Female; Heart Failure; Heart Rate; Humans; Hypertension; Incidence; Male; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Tetrazoles; Valine; Valsartan | 2007 |
[The relationship between the gene polymorphism of TGF-beta1 and early renal injury in patients with essential hypertension, and the effect of the gene polymorphism of TGF- beta1 on the individual treatment with valsartan].
Topics: Aged; Albuminuria; Antihypertensive Agents; Blood Pressure; Female; Genetic Predisposition to Disease; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Tetrazoles; Time Factors; Transforming Growth Factor beta1; Treatment Outcome; Valine; Valsartan | 2007 |
[Intensive blood pressure reduction in patients with increased cardiovascular risk with high-dose combination therapy of 160 mg valsartan plus 25 mg hydrochlorothiazide. Results of the MACHT II observational study].
Topics: Antihypertensive Agents; Death, Sudden, Cardiac; Drug Administration Schedule; Drug Therapy, Combination; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Risk Assessment; Risk Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2007 |
Beneficial effects of valsartan in asymptomatic individuals with vascular or cardiac abnormalities: the DETECTIV Pilot Study.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Cardiovascular Diseases; Comorbidity; Coronary Artery Disease; Disease Progression; Double-Blind Method; Exercise Test; Female; Fluorescein Angiography; Health Status Indicators; Heart Diseases; Humans; Hypertension; Male; Middle Aged; Natriuretic Peptide, Brain; Pilot Projects; Predictive Value of Tests; Tetrazoles; Valine; Valsartan | 2007 |
Albuminuria response to very high-dose valsartan in type 2 diabetes mellitus.
Topics: Aged; Albuminuria; Antihypertensive Agents; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2007 |
Comparative effects of telmisartan and valsartan on insulin resistance in hypertensive patients with metabolic syndrome.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Female; Humans; Hypertension; Insulin Resistance; Male; Metabolic Syndrome; Middle Aged; Telmisartan; Tetrazoles; Valine; Valsartan | 2007 |
Angiotensin receptor blocker improves coronary flow velocity reserve in hypertensive patients: comparison with calcium channel blocker.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Blood Flow Velocity; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Echocardiography; Female; Humans; Hyperemia; Hypertension; Male; Middle Aged; Nifedipine; Tetrazoles; Valine; Valsartan | 2007 |
Efficacy and safety of valsartan 160/HCTZ 25 mg in fixed combination in hypertensive patients not controlled by candesartan 32 mg plus HCTZ 25 mg in free combination.
Topics: Benzimidazoles; Biphenyl Compounds; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Prospective Studies; Tetrazoles; Valine; Valsartan | 2007 |
Effect of valsartan compared with valsartan/hydrochlorothiazide on plasma levels of cellular adhesion molecules: the Val-MARC trial.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Drug Therapy, Combination; Epidemiologic Methods; Female; Humans; Hydrochlorothiazide; Hypertension; Intercellular Adhesion Molecule-1; Male; Middle Aged; Tetrazoles; Valine; Valsartan; Vascular Cell Adhesion Molecule-1 | 2008 |
[Therapeutic efficacy of valsartan and valsartan/HCTZ in mild to moderate hypertensive patients].
Topics: Adult; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2007 |
Comparison of effects of telmisartan and valsartan on late lumen loss and inflammatory markers after sirolimus-eluting stent implantation in hypertensive patients.
Topics: Adiponectin; Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biomarkers; Cholesterol; Cholesterol, LDL; Coronary Stenosis; Drug-Eluting Stents; Female; Humans; Hypertension; Immunosuppressive Agents; Interleukin-6; Male; Middle Aged; Single-Blind Method; Sirolimus; Telmisartan; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan | 2007 |
Effect of telmisartan on forearm postischemic hyperemia and serum asymmetric dimethylarginine levels.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Arginine; Benzimidazoles; Benzoates; Blood Pressure; Endothelium, Vascular; Female; Forearm; Humans; Hyperemia; Hypertension; Male; Middle Aged; Telmisartan; Tetrazoles; Valine; Valsartan | 2007 |
Aldosterone breakthrough during angiotensin II receptor blockade in hypertensive patients with diabetes mellitus.
Topics: Aged; Albuminuria; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2007 |
A randomized, double-blind study of valsartan versus metoprolol on arterial distensibility and endothelial function in essential hypertension.
Topics: Adult; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Brachial Artery; Carotid Arteries; Dose-Response Relationship, Drug; Double-Blind Method; Elasticity; Endothelium, Vascular; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Sympathetic Nervous System; Tetrazoles; Tunica Intima; Tunica Media; Ultrasonography; Valine; Valsartan | 2008 |
Effects of the angiotensin II receptor blockers telmisartan versus valsartan in combination with hydrochlorothiazide: a large, confirmatory trial.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Telmisartan; Tetrazoles; Valine; Valsartan | 2008 |
[Influence of valsartan, fluvastatin extended release and their combination on arterial pressure, parameters of lipid metabolism, and endothelial function in patients with hypertensive disease].
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Cholesterol; Delayed-Action Preparations; Endothelium, Vascular; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Indoles; Male; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan | 2007 |
Reduced incidence of new-onset atrial fibrillation with angiotensin II receptor blockade: the VALUE trial.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Atrial Fibrillation; Drug Therapy, Combination; Female; Humans; Hypertension; Incidence; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Efficacy of the combination of amlodipine and valsartan in patients with hypertension uncontrolled with previous monotherapy: the Exforge in Failure after Single Therapy (EX-FAST) study.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Retreatment; Tetrazoles; Valine; Valsartan | 2008 |
Ambulatory blood pressure-lowering effects of valsartan and enalapril after a missed dose in previously untreated patients with hypertension: a prospective, randomized, open-label, blinded end-point trial.
Topics: Antihypertensive Agents; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cholesterol; Enalapril; Female; Humans; Hypertension; Male; Medication Adherence; Middle Aged; Prospective Studies; Severity of Illness Index; Tetrazoles; Uric Acid; Valine; Valsartan | 2008 |
Renal protective effect in hypertensive patients: the high doses of angiotensin II receptor blocker (HARB) study.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Hypertension; Kidney; Male; Middle Aged; Proteinuria; Tetrazoles; Valine; Valsartan | 2007 |
Comparative evaluation of effect of valsartan/amlodipine and atenolol/amlodipine combinations on atrial fibrillation recurrence in hypertensive patients with type 2 diabetes mellitus.
Topics: Aged; Amlodipine; Anti-Arrhythmia Agents; Antihypertensive Agents; Atenolol; Atrial Fibrillation; Blood Pressure; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Electrocardiography; Female; Humans; Hypertension; Male; Middle Aged; Propafenone; Prospective Studies; Secondary Prevention; Tetrazoles; Valine; Valsartan | 2008 |
Valsartan Amlodipine Randomized Trial (VART): design, methods, and preliminary results.
Topics: 3-Iodobenzylguanidine; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Data Interpretation, Statistical; Endpoint Determination; Female; Follow-Up Studies; Humans; Hypertension; Informed Consent; Male; Middle Aged; Patient Selection; Prospective Studies; Radionuclide Imaging; Radiopharmaceuticals; Research Design; Risk Factors; Sample Size; Tetrazoles; Ultrasonography; Valine; Valsartan | 2008 |
High-risk myocardial infarction in the young: the VALsartan In Acute myocardial iNfarcTion (VALIANT) trial.
Topics: Adult; Age Factors; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Cardiovascular Diseases; Diabetes Complications; Female; Humans; Hypertension; Kaplan-Meier Estimate; Male; Middle Aged; Mortality; Multivariate Analysis; Myocardial Infarction; Proportional Hazards Models; Risk Factors; Sex Factors; Smoking; Survivors; Tetrazoles; Valine; Valsartan | 2008 |
Transforming growth factor-beta1 is associated with kidney damage in patients with essential hypertension: renoprotective effect of ACE inhibitor and/or angiotensin II receptor blocker.
Topics: Administration, Inhalation; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Double-Blind Method; Female; Humans; Hypertension; Kidney; Kidney Diseases; Male; Middle Aged; Prospective Studies; Tetrazoles; Transforming Growth Factor beta1; Valine; Valsartan | 2008 |
Effects of valsartan or amlodipine on endothelial function and oxidative stress after one year follow-up in patients with essential hypertension.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Asian People; Biomarkers; Blood Pressure; Brachial Artery; Calcium Channel Blockers; Deoxyguanosine; Dinoprost; Endothelium, Vascular; Female; Follow-Up Studies; Heart Rate; Humans; Hypertension; Male; Middle Aged; Oxidative Stress; Regional Blood Flow; Tetrazoles; Valine; Valsartan; Vasodilation | 2008 |
Valsartan improves arterial stiffness in type 2 diabetes independently of blood pressure lowering.
Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arteries; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Antiproteinuric effects of angiotensin receptor blockers: telmisartan versus valsartan in hypertensive patients with type 2 diabetes mellitus and overt nephropathy.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Arginine; Benzimidazoles; Benzoates; Blood Pressure; C-Reactive Protein; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dinoprost; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Proteinuria; Renin-Angiotensin System; Telmisartan; Tetrazoles; Valine; Valsartan | 2008 |
Effective and safe reduction of blood pressure with the combination of amlodipine 5 mg and valsartan 160 mg in hypertensive patients not controlled by calcium channel blocker monotherapy.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2008 |
Combination therapy versus monotherapy as initial treatment for stage 2 hypertension: a prespecified subgroup analysis of a community-based, randomized, open-label trial.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Retrospective Studies; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: a comparative study of the efficacy and safety against amlodipine.
Topics: Adult; Aged; Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Dizziness; Double-Blind Method; Drug Administration Schedule; Edema; Female; Headache; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1996 |
Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy and safety compared with placebo and enalapril.
Topics: Adult; Age Factors; Aged; Angiotensin II; Antihypertensive Agents; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 1996 |
Valsartan, a new angiotensin II receptor antagonist: a double-blind study comparing the incidence of cough with lisinopril and hydrochlorothiazide.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cough; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 1997 |
Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy and safety compared to hydrochlorothiazide.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Antihypertensive Agents; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1997 |
Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy, tolerability and safety compared to an angiotensin-converting enzyme inhibitor, lisinopril.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Lisinopril; Male; Middle Aged; Safety; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1997 |
The Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial of cardiovascular events in hypertension. Rationale and design.
Topics: Aged; Amlodipine; Angiotensin II; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Prospective Studies; Research Design; Risk Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1998 |
Valsartan and atenolol in patients with severe essential hypertension.
Topics: Adult; Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Atenolol; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 1998 |
Influence of the angiotensin II antagonist valsartan on left ventricular hypertrophy in patients with essential hypertension.
Topics: Angiotensin II; Antihypertensive Agents; Atenolol; Blood Pressure; Double-Blind Method; Echocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1998 |
Valsartan and hydrochlorothiazide in patients with essential hypertension. A multiple dose, double-blind, placebo controlled trial comparing combination therapy with monotherapy.
Topics: Adult; Angiotensin II; Antihypertensive Agents; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Fatigue; Female; Headache; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1998 |
[The hypotensive effect and tolerance of valsartan (Diovan) in hypertension in a general clinical practice].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Quality of Life; Tetrazoles; Time Factors; Valine; Valsartan | 1999 |
A comparison of the angiotensin II antagonists valsartan and losartan in the treatment of essential hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Diastole; Dizziness; Double-Blind Method; Female; Headache; Humans; Hypertension; Losartan; Male; Middle Aged; Patient Dropouts; Systole; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1999 |
Dose-response efficacy of valsartan, a new angiotensin II receptor blocker.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Posture; Renin; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1999 |
[Diovan efficacy and tolerance in mild and moderate hypertension].
Topics: Adult; Angiotensin II; Antihypertensive Agents; Blood Pressure; Drug Hypersensitivity; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Safety; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1999 |
Angiotensin II antagonism and the heart: valsartan in left ventricular hypertrophy.
Topics: Aged; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1999 |
Long-term potential of angiotensin receptor blockade for cardiovascular protection in hypertension: the VALUE trial. Valsartan Antihypertensive Long-term Use Evaluation.
Topics: Amlodipine; Animals; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Clinical Trials as Topic; Humans; Hypertension; Tetrazoles; Valine; Valsartan | 1999 |
Treatment with the angiotensin II antagonist valsartan in patients with chronic renal failure and hypertension.
Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Renal Circulation; Tetrazoles; Valine; Valsartan | 1999 |
Influence of the angiotensin II antagonist valsartan on left ventricular hypertrophy in patients with essential hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Atenolol; Diuretics; Drug Interactions; Heart Ventricles; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Organ Size; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Research Design; Tetrazoles; Valine; Valsartan | 1999 |
A comparison of valsartan and captopril in patients with essential hypertension in Indonesia.
Topics: Adult; Aged; Antihypertensive Agents; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1999 |
Assessment of angiotensin II receptor blockade in humans using a standardized angiotensin II receptor-binding assay.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biomarkers; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Irbesartan; Losartan; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reproducibility of Results; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents | 1999 |
Effects of valsartan on left ventricular diastolic function in patients with mild or moderate essential hypertension: comparison with enalapril.
Topics: Adult; Angiography; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Double-Blind Method; Enalapril; Exercise Test; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Radionuclide Imaging; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan; Ventricular Function, Left | 1999 |
Safety of the combination of valsartan and benazepril in patients with chronic renal disease. European Group for the Investigation of Valsartan in Chronic Renal Disease.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure; Creatinine; Drug Combinations; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Pilot Projects; Potassium; Proteinuria; Safety; Tetrazoles; Valine; Valsartan | 2000 |
The effect of valsartan and captopril on lipid parameters in patients with type II diabetes mellitus and nephropathy.
Topics: Adult; Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Hypertension; Lipids; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 1999 |
Efficacy and safety of valsartan compared with enalapril at different altitudes.
Topics: Adult; Altitude; Antihypertensive Agents; Colombia; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Safety; Tetrazoles; Valine; Valsartan | 2000 |
Additive hypotensive effect of angiotensin-converting enzyme inhibition and angiotensin-receptor antagonism in essential hypertension.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure; Cross-Over Studies; Diastole; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Humans; Hypertension; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Systole; Tetrazoles; Time Factors; Valine; Valsartan | 2000 |
Efficacy of valsartan in patients aged > or =65 years with systolic hypertension.
Topics: Aged; Antihypertensive Agents; Double-Blind Method; Female; Humans; Hypertension; Male; Placebos; Tetrazoles; Valine; Valsartan | 2000 |
[Diovan effectiveness in combined treatment of severe arterial hypertension].
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Clonidine; Diuretics; Drug Therapy, Combination; Electrocardiography, Ambulatory; Female; Humans; Hypertension; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Valine; Valsartan | 2000 |
A prospective, randomized, open-label trial comparing telmisartan 80 mg with valsartan 80 mg in patients with mild to moderate hypertension using ambulatory blood pressure monitoring.
Topics: Administration, Oral; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Female; Humans; Hypertension; Male; Middle Aged; Patient Compliance; Single-Blind Method; Telmisartan; Tetrazoles; Valine; Valsartan | 2000 |
Sexual activity in hypertensive men treated with valsartan or carvedilol: a crossover study.
Topics: Adult; Antihypertensive Agents; Carbazoles; Carvedilol; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Male; Middle Aged; Propanolamines; Sexual Behavior; Tetrazoles; Valine; Valsartan | 2001 |
Treatment of hypertension with valsartan combined with spironolactone.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Spironolactone; Tetrazoles; Valine; Valsartan | 2000 |
Canadian valsartan study in patients with mild-to-moderate hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Canada; Chronotherapy; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Racial Groups; Sex Factors; Single-Blind Method; Tetrazoles; Valine; Valsartan | 2001 |
Valsartan alone or with a diuretic or ACE inhibitor as treatment for African American hypertensives: relation to salt intake.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Black People; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pilot Projects; Prospective Studies; Sodium Chloride Symporter Inhibitors; Sodium, Dietary; Tetrazoles; Valine; Valsartan | 2001 |
Characteristics of 15,314 hypertensive patients at high coronary risk. The VALUE trial. The Valsartan Antihypertensive Long-term Use Evaluation.
Topics: Aged; Aged, 80 and over; Algorithms; Antihypertensive Agents; Clinical Protocols; Coronary Disease; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Risk Factors; Tetrazoles; Valine; Valsartan | 2001 |
[Experience in the use of valsartan with the aim to inhibit progression of kidney failure in patients with chronic glomerulonephritis].
Topics: Adult; Antihypertensive Agents; Chronic Disease; Female; Follow-Up Studies; Glomerulonephritis; Humans; Hypertension; Kidney Failure, Chronic; Kidney Function Tests; Male; Middle Aged; Proteinuria; Tetrazoles; Time Factors; Valine; Valsartan | 2001 |
Losartan versus valsartan in the treatment of patients with mild to moderate essential hypertension: data from a multicenter, randomized, double-blind, 12-week trial.
Topics: Adult; Antihypertensive Agents; Double-Blind Method; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Tetrazoles; Treatment Outcome; Uric Acid; Valine; Valsartan | 2001 |
A multicenter, randomized double-blind study of valsartan/hydrochlorothiazide combination versus amlodipine in patients with mild to moderate hypertension.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2001 |
[Antihypertensive effect of valsartan 80 mg and hydrochlorothiazide 12.5 mg evaluated by ambulatory blood pressure monitoring].
Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2001 |
Combination of hydrochlorothiazide or benazepril with valsartan in hypertensive patients unresponsive to valsartan alone.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure; Diuretics; Drug Combinations; Drug Resistance; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan | 2001 |
Antihypertensive effects of valsartan/hydrochlorothiazide combination in essential hypertension.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Kinetics; Male; Middle Aged; Tetrazoles; Therapeutic Equivalency; Treatment Outcome; Valine; Valsartan | 2001 |
Trough:peak ratio and smoothness index in the evaluation of 24-h blood pressure control in hypertension: a comparative study between valsartan/hydrochlorothiazide combination and amlodipine.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Tetrazoles; Time Factors; Valine; Valsartan | 2002 |
The efficacy of valsartan in essential hypertension and its effects on left ventricular hypertrophy.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Cohort Studies; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Middle Aged; Tetrazoles; Therapeutic Equivalency; Treatment Outcome; Ultrasonography; Valine; Valsartan | 2002 |
Reduction in arterial stiffness with angiotensin II antagonist is comparable with and additive to ACE inhibition.
Topics: Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Arteries; Blood Pressure; Captopril; Cross-Over Studies; Drug Synergism; Drug Therapy, Combination; Humans; Hypertension; Middle Aged; Pulse; Tetrazoles; Valine; Valsartan | 2002 |
Effect of indomethacin on the antihypertensive efficacy of valsartan and lisinopril: a multicentre study.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Chronic Disease; Drug Interactions; Female; Humans; Hypertension; Indomethacin; Lisinopril; Male; Middle Aged; Osteoarthritis; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2002 |
Effects of selective angiotensin II receptor blockade on sympathetic nerve activity in primary hypertensive subjects.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Double-Blind Method; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Muscle, Skeletal; Receptor, Angiotensin, Type 1; Sympathetic Nervous System; Tetrazoles; Valine; Valsartan; Vasodilator Agents | 2002 |
An ambulatory blood pressure monitoring study of the comparative antihypertensive efficacy of two angiotensin II receptor antagonists, irbesartan and valsartan.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Female; Humans; Hypertension; Irbesartan; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2002 |
Efficacy and tolerability of valsartan in patients with mild to moderate essential hypertension.
Topics: Administration, Oral; Adult; Aged; Antihypertensive Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Probability; Reference Values; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2002 |
Effect of antihypertensive treatment with valsartan or atenolol on sexual activity and plasma testosterone in hypertensive men.
Topics: Adult; Analysis of Variance; Antihypertensive Agents; Atenolol; Coitus; Double-Blind Method; Humans; Hypertension; Male; Middle Aged; Testosterone; Tetrazoles; Valine; Valsartan | 2002 |
362 other study(ies) available for valsartan and Hypertension
| Article | Year |
|---|---|
Synthesis and biological evaluation of new fluorine substituted derivatives as angiotensin II receptor antagonists with anti-hypertension and anti-tumor effects.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Antineoplastic Agents; Cell Line, Tumor; Humans; Hydrocarbons, Fluorinated; Hypertension; Male; Mice; Mice, Nude; Prostatic Neoplasms; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Structure-Activity Relationship; Xenograft Model Antitumor Assays | 2012 |
The ESC Guidelines on heart failure, sacubitril-valsartan in resistant hypertension, and new therapeutic targets in myocardial hypertrophy.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Drug Combinations; Heart Failure; Humans; Hypertension; Hypertrophy; Neprilysin; Stroke Volume; Tetrazoles; Valsartan | 2021 |
Targeting Cyclic Guanylate Monophosphate in Resistant Hypertension and Heart Failure: Are Sacubitril/Valsartan and Vericiguat Synergistic and Effective in Both Conditions?
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Drug Combinations; Heart Failure; Heterocyclic Compounds, 2-Ring; Humans; Hypertension; Neprilysin; Pyrimidines; Stroke Volume; Tetrazoles; Valsartan | 2021 |
Tom Nolan's research reviews-26 November 2021.
Topics: Adrenergic beta-Antagonists; Aminobutyrates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Cats; COVID-19; COVID-19 Serotherapy; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dogs; Drug Combinations; Gastric Inhibitory Polypeptide; Heart Sounds; History, 20th Century; Humans; Hypertension; Immunization, Passive; Incretins; Insulin Glargine; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; SARS-CoV-2; Thiazides; Valsartan | 2021 |
Cancer Risk of Angiotensin II Receptor Blocker Valsartan: A Population-based Study.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Neoplasms; Tetrazoles; Valine; Valsartan | 2022 |
Effects of Sacubitril/Valsartan on resistant hypertension and myocardial work in hemodialysis patients.
Topics: Adult; Aminobutyrates; Biphenyl Compounds; Double-Blind Method; Drug Combinations; Fatigue; Heart; Humans; Hypertension; Middle Aged; Prospective Studies; Renal Dialysis; Valsartan | 2022 |
Highly suspected valsartan-induced chronic erythema nodosum migrans in a patient with hypertension: a case report.
Topics: Aged; Chronic Disease; Erythema Nodosum; Female; Humans; Hypertension; Valsartan | 2022 |
Efficacy of angiotensin receptor neprilysin inhibitor in Asian patients with refractory hypertension.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Drug Combinations; Humans; Hypertension; Neprilysin; Receptors, Angiotensin; Tetrazoles; Valsartan | 2022 |
Sacubitril/Valsartan Improves Sexual Function and Fibrosis of the Clitoral and Vaginal Tissues in Female Spontaneously Hypertensive Rats.
Topics: Aminobutyrates; Animals; Biphenyl Compounds; Female; Fibrosis; Hypertension; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Valsartan | 2022 |
Sacubitril/valsartan-A new weapon for fighting the hypertension paradox.
Topics: Aminobutyrates; Biphenyl Compounds; Drug Combinations; Heart Failure; Humans; Hypertension; Tetrazoles; Valsartan | 2022 |
Effect of Yiqi Huayu Pinggan Zishen Formula Combined with Valsartan in the Treatment of Hypertension and Its Effect on MMP-9, Ang II, and MCP-1.
Topics: Angiotensin II; Antihypertensive Agents; Chemokine CCL2; Drugs, Chinese Herbal; Humans; Hypertension; Matrix Metalloproteinase 9; Syndrome; Valsartan | 2022 |
Effectiveness and safety of sacubitril/valsartan for patients with hypertension and heart failure in the real-world setting: A retrospective study in China.
Topics: Adult; Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Creatinine; Drug Combinations; Heart Failure; Humans; Hypertension; Natriuretic Peptide, Brain; Retrospective Studies; Tetrazoles; Uric Acid; Valsartan | 2022 |
[Clinical case: early connection of valsartan/sacubitril in the treatment of hypertension].
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Drug Combinations; Heart Failure; Humans; Hypertension; Metabolic Syndrome; Stroke Volume; Tetrazoles; Valsartan | 2022 |
Eco-friendly spectrophotometric evaluation of triple-combination therapies in the treatment strategy of patients suffering from hypertension during coronavirus pandemic - Spectralprint recognition study.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Coronavirus; Humans; Hydrochlorothiazide; Hypertension; Leukemia, Myeloid, Acute; Pandemics; Spectrophotometry; Valsartan | 2022 |
The impact of Sacubitril/Valsartan on cardiac fibrosis early after myocardial infarction in hypertensive rats.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Drug Combinations; Fibrosis; Heart Failure; Hypertension; Myocardial Infarction; Rats; Rats, Inbred SHR; Tetrazoles; Valsartan | 2022 |
Implication of sacubitril/valsartan on N-terminal pro B-type natriuretic peptide levels in hypertensive patients.
Topics: Aged; Aminobutyrates; Biphenyl Compounds; Heart Failure; Humans; Hypertension; Natriuretic Peptide, Brain; Retrospective Studies; Tetrazoles; Valsartan | 2022 |
Blood pressure-independent renoprotective effects of small interference RNA targeting liver angiotensinogen in experimental diabetes.
Topics: Albuminuria; Angiotensin II; Animals; Blood Pressure; Diabetes Mellitus, Experimental; Humans; Hypertension; Kidney Diseases; Liver; Rats; Renin; Renin-Angiotensin System; RNA, Small Interfering; Valsartan | 2023 |
Benefits of Valsartan and Amlodipine in Lipolysis through PU.1 Inhibition in Fructose-Induced Adiposity.
Topics: Activating Transcription Factor 3; Adiposity; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Fructose; Humans; Hypertension; Lipase; Lipolysis; Monoacylglycerol Lipases; Obesity; Stearoyl-CoA Desaturase; Tetrazoles; Triglycerides; Valsartan | 2022 |
Effectiveness and safety evaluation of sacubitril/valsartan in blood pressure control and clinical outcomes for elderly patients with heart failure and hypertension: A prospective cohort study.
Topics: Aged; Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure; Drug Combinations; Heart Failure; Humans; Hypertension; Hypotension; Prospective Studies; Stroke Volume; Tetrazoles; Valsartan; Ventricular Function, Left | 2023 |
Effects of the July 2018 worldwide valsartan recall and shortage on global trends in antihypertensive medication use: a time-series analysis in 83 countries.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Humans; Hypertension; Tetrazoles; Valsartan | 2023 |
Efficacy and safety of sacubitril/valsartan after switching from azilsartan in hemodialysis patients with hypertension.
Topics: Aged; Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Drug Combinations; Heart Failure; Humans; Hypertension; Male; Stroke Volume; Tetrazoles; Valsartan | 2023 |
Efficacy and safety of single pill combination of amlodipine and valsartan in hypertensive Saudi patients.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Therapy, Combination; Humans; Hypertension; Leukemia, Myeloid, Acute; Prospective Studies; Saudi Arabia; Tetrazoles; Valsartan | 2023 |
Pharmacokinetics and pharmacodynamics of sacubitril/valsartan in peritoneal dialysis patients.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Cross-Sectional Studies; Dialysis Solutions; Drug Combinations; Heart Failure; Humans; Hypertension; Peritoneal Dialysis; Stroke Volume; Tetrazoles; Valsartan; Ventricular Function, Left | 2023 |
Neferine ameliorates hypertensive vascular remodeling modulating multiple signaling pathways in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Collagen; Hypertension; Male; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pulse Wave Analysis; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA; Signal Transduction; Transforming Growth Factor beta1; Valsartan; Vascular Remodeling | 2023 |
Understanding the dosing-time-dependent antihypertensive effect of valsartan and aspirin through mathematical modeling.
Topics: Antihypertensive Agents; Aspirin; Humans; Hypertension; Tetrazoles; Valine; Valsartan | 2023 |
Improved Persistence to Medication, Decreased Cardiovascular Events and Reduced All-Cause Mortality in Hypertensive Patients With Use of Single-Pill Combinations: Results From the START-Study.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Humans; Hypertension; Medication Adherence; Retrospective Studies; Tetrazoles; Valsartan | 2023 |
Sacubitril/valsartan reverses cardiac structure and function in experimental model of hypertension-induced hypertrophic cardiomyopathy.
Topics: Animals; Cardiomyopathy, Hypertrophic; Hypertension; Models, Theoretical; Myocytes, Cardiac; Rats; Rats, Inbred WKY; Tetrazoles; Valsartan | 2023 |
Effect of Fixed-dose Combination Amlodipine/Valsartan in Comparison to Two Drug Combination Nebivolol/Valsartan on 24-Hour Ambulatory Blood Pressure.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Humans; Hypertension; Nebivolol; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2023 |
Effects of Valsartan and Amlodipine Tablets Combined with α-Lipoic Acid on T-AOC, IL-6 and β2-MG Levels in Patients with Diabetic Nephropathy.
Topics: Amlodipine; Antihypertensive Agents; Antioxidants; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Hypertension; Interleukin-6; Tablets; Thioctic Acid; Valsartan | 2023 |
Effectiveness and Safety of a Fixed-Dose Combination of Valsartan and Rosuvastatin (Rovatitan
Topics: Antihypertensive Agents; Cholesterol, LDL; Humans; Hyperlipidemias; Hypertension; Rosuvastatin Calcium; Treatment Outcome; Valsartan | 2023 |
Impact of multimorbidity on mortality in heart failure with reduced ejection fraction: which comorbidities matter most? An analysis of PARADIGM-HF and ATMOSPHERE.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Atmosphere; Biphenyl Compounds; Comorbidity; Drug Combinations; Heart Failure; Humans; Hypertension; Multimorbidity; Stroke; Stroke Volume; Tetrazoles; Valsartan | 2023 |
Valsartan, Losartan and Irbesartan use in the USA, UK, Canada and Denmark after the nitrosamine recalls: a descriptive cohort study.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Canada; Cohort Studies; Denmark; Humans; Hypertension; Irbesartan; Losartan; Retrospective Studies; Tetrazoles; United Kingdom; Valsartan | 2023 |
Marked Increase in Urinary C-peptide Levels after Treatment with Sacubitril/Valsartan in Patients with Type 2 Diabetes Mellitus and Hypertension.
Topics: Aged; Angiotensin Receptor Antagonists; Biphenyl Compounds; C-Peptide; Diabetes Mellitus, Type 2; Drug Combinations; Heart Failure; Humans; Hypertension; Male; Stroke Volume; Tetrazoles; Valsartan | 2023 |
A collaborative study of the impact of N-nitrosamines presence and ARB recall on ARB utilization - results from IQVIA™ Disease Analyzer Germany.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Germany; Humans; Hypertension; Irbesartan; Losartan; Nitrosamines; Valsartan | 2023 |
Sacubitril/valsartan reduces susceptibility to atrial fibrillation by improving atrial remodeling in spontaneously hypertensive rats.
Topics: Aminobutyrates; Angiotensins; Animals; Antihypertensive Agents; Atrial Fibrillation; Atrial Remodeling; Biphenyl Compounds; Drug Combinations; Hypertension; Neprilysin; Rats; Rats, Inbred SHR; Tetrazoles; Valsartan | 2023 |
Effects of 5-fluorouracil Co-administration on Blood Pressure in Patients Maintained on Antihypertensives: a Retrospective Case Series.
Topics: Amlodipine; Antihypertensive Agents; Antineoplastic Agents; Blood Pressure; Cytochrome P-450 CYP3A; Drug Therapy, Combination; Fluorouracil; Humans; Hypertension; Nifedipine; Retrospective Studies; Tetrazoles; Valine; Valsartan | 2023 |
Therapeutic improvements of nifedipine controlled-release tablets combined with sacubitril valsartan on patients with diabetic nephropathy complicated with hypertension.
Topics: Biphenyl Compounds; Delayed-Action Preparations; Diabetes Mellitus; Diabetic Nephropathies; Drug Combinations; Humans; Hypertension; Nifedipine; Tetrazoles; Valsartan | 2023 |
Consensus document on the use of sacubitril/valsartan in patients with heart failure: Consejo Interamericano de Falla Cardiaca e Hipertensión Pulmonar (CIFACAH) of the Inter-American Society of Cardiology (IASC).
Topics: Angiotensin Receptor Antagonists; Cardiology; Consensus; Heart Failure; Humans; Hypertension; Quality of Life; Stroke Volume; Tetrazoles; United States; Valsartan; Ventricular Dysfunction, Left | 2023 |
Population Impact of Generic Valsartan Recall.
Topics: Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Drugs, Generic; Female; Humans; Hypertension; Male; Middle Aged; Valsartan | 2020 |
Angiotensin-neprilysin inhibition confers renoprotection in rats with diabetes and hypertension by limiting podocyte injury.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diabetes Mellitus; Drug Combinations; Hypertension; Male; Neprilysin; Podocytes; Protective Agents; Rats; Tetrazoles; Valsartan | 2020 |
A post-marketing survey evaluating the safety and efficacy of a fixed-dose single-pill combination of cilnidipine and valsartan in patients with hypertension: Real-world JSH 2014 and 2019 implementations.
Topics: Aged; Antihypertensive Agents; Blood Pressure Determination; Dihydropyridines; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hypertension; Japan; Male; Product Surveillance, Postmarketing; Valsartan | 2020 |
[Features of fibrosis and disorders of the collagen metabolism of the interstitial matrix of the myocardium in patients with arterial hypertension and possibilities of their correction with sartname.]
Topics: Aged; Case-Control Studies; Collagen; Female; Fibrosis; Heart; Humans; Hypertension; Myocardium; Spironolactone; Valsartan | 2019 |
Tandospirone enhances the anti-myocardial fibrosis effect of valsartan in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Cardiomyopathies; Drug Synergism; Fibrosis; Gene Expression; Hypertension; Immunohistochemistry; Isoindoles; Male; Models, Biological; Myocardium; Piperazines; Pyrimidines; Rats; Rats, Inbred SHR; Serotonin Receptor Agonists; Smad3 Protein; Transforming Growth Factor beta; Valsartan | 2020 |
Impact of the Generic Valsartan Recall in Alberta, Canada.
Topics: Aged; Alberta; Antihypertensive Agents; Carcinogens; Databases, Factual; Dimethylnitrosamine; Drug Recalls; Drug Substitution; Drugs, Generic; Emergency Service, Hospital; Humans; Hypertension; Office Visits; Stroke; Valsartan | 2020 |
Single-pill combination of cilnidipine, an L-/N-type calcium channel blocker, and valsartan effectively reduces home pulse pressure in patients with uncontrolled hypertension and sympathetic hyperactivity: The HOPE-Combi survey.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Humans; Hypertension; Tetrazoles; Valsartan | 2020 |
Public Health Outcomes May Differ After Switching from Brand-Name to Generic Angiotensin II Receptor Blockers.
Topics: Aged; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Canada; Cohort Studies; Female; Humans; Hypertension; Male; Public Health; Receptors, Angiotensin; Retrospective Studies; Tetrazoles; Treatment Outcome; Valsartan | 2020 |
Differential effects of low-dose sacubitril and/or valsartan on renal disease in salt-sensitive hypertension.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Drug Combinations; Hypertension; Kidney Diseases; Male; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary; Tetrazoles; Valsartan | 2020 |
Clinical experience with therapeutic dose of Low-Molecular-Weight Heparin.
Topics: Aged; Anti-Inflammatory Agents; Anticoagulants; Antihypertensive Agents; Azithromycin; Combined Modality Therapy; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Therapy, Combination; Enoxaparin; Humans; Hydroxychloroquine; Hypertension; Male; Oxygen Inhalation Therapy; Pandemics; Pneumonia, Viral; Thrombophilia; Tomography, X-Ray Computed; Valsartan | 2020 |
Antihypertensive Efficacy of LCZ696 (Sacubitril/Valsartan) in Hypertension.
Topics: Aminobutyrates; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Drug Combinations; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Valsartan | 2020 |
Hierarchical modeling of blood pressure determinants and outcomes following valsartan treatment in hypertensive patients with known comorbidities: pooled analysis of six prospective real-world studies including 11,999 patients.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Comorbidity; Diabetes Mellitus; Female; Humans; Hypertension; Male; Middle Aged; Models, Statistical; Prospective Studies; Risk Factors; Valsartan | 2021 |
No evidence for brain renin-angiotensin system activation during DOCA-salt hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Brain; Brain Stem; Desoxycorticosterone Acetate; Hypertension; Male; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary; Valsartan | 2021 |
Single-pill combination of cilnidipine, an l-/n-type calcium channel blocker, and valsartan reduces the day-by-day variability of morning home systolic blood pressure in patients with treated hypertension: A sub-analysis of the HOPE-combi survey.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Humans; Hypertension; Tetrazoles; Valsartan | 2021 |
Gender-stratified hierarchical modeling of patient and physician determinants of antihypertensive treatment outcomes: pooled analysis of seven prospective real-world studies with 17,044 patients.
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Male; Physicians; Prospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2021 |
Time-Dependent Effects of Individual and Combined Treatments With Nebivolol, Lisinopril, and Valsartan on Blood Pressure and Vascular Reactivity to Angiotensin II and Norepinephrine.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Drug Combinations; Hypertension; Lisinopril; Male; Nebivolol; Norepinephrine; Rats, Inbred SHR; Rats, Wistar; Time; Valsartan; Vascular Resistance; Vasoconstrictor Agents | 2021 |
Angiotensin receptor neprilysin inhibitor for patients with heart failure and reduced ejection fraction: Real-world experience from Turkey (ARNi-TR).
Topics: Aged; Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Diuretics; Drug Combinations; Female; Furosemide; Glycated Hemoglobin; Heart Failure; Humans; Hypertension; Male; Middle Aged; Natriuretic Peptide, Brain; Neprilysin; Peptide Fragments; Retrospective Studies; Stroke Volume; Turkey; Valsartan; Ventricular Dysfunction, Left | 2021 |
The role of sacubitril/valsartan in the treatment of chronic heart failure with reduced ejection fraction in hypertensive patients with comorbidities: From clinical trials to real-world settings.
Topics: Aged; Aminobutyrates; Biphenyl Compounds; Chronic Disease; Clinical Studies as Topic; Drug Combinations; Female; Heart Failure; Humans; Hypertension; Male; Patient Readmission; Prognosis; Severity of Illness Index; Stroke Volume; Treatment Outcome; Valsartan; Ventricular Dysfunction, Left | 2020 |
Sacubitril/valsartan for heart failure with preserved ejection fraction and resistant hypertension: one shot for a double strike?
Topics: Aminobutyrates; Biphenyl Compounds; Drug Combinations; Heart Failure; Humans; Hypertension; Stroke Volume; Tetrazoles; Valsartan | 2021 |
Comparative beneficial effects of nebivolol and nebivolol/valsartan combination against mitochondrial dysfunction in angiotensin II-induced pathology in H9c2 cardiomyoblasts.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiomegaly; Cell Culture Techniques; Drug Combinations; Heart; Hypertension; Inflammation; Mechanistic Target of Rapamycin Complex 1; Mitochondria; Myoblasts, Cardiac; Myocardium; Nebivolol; Organelle Biogenesis; Oxidative Stress; Rats; Reactive Oxygen Species; Valsartan | 2021 |
Oxidative stress: link between hypertension and diabetes.
Topics: Amlodipine; Diabetes Mellitus, Type 2; Humans; Hypertension; Oxidative Stress; Valsartan | 2017 |
mRNA levels of circadian clock components Bmal1 and Per2 alter independently from dosing time-dependent efficacy of combination treatment with valsartan and amlodipine in spontaneously hypertensive rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Aorta; ARNTL Transcription Factors; Blood Pressure; Circadian Clocks; Drug Administration Schedule; Drug Therapy, Combination; Heart Ventricles; Hypertension; Kidney; Male; Period Circadian Proteins; Plasminogen Activator Inhibitor 1; Rats; Rats, Inbred SHR; RNA, Messenger; Valsartan | 2017 |
Potential Cardiovascular and Renal Protective Effects of Vitamin D and Coenzyme Q
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Cardiovascular Diseases; Hypertension; Kidney Diseases; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Ubiquinone; Valsartan; Vitamin D; Vitamins | 2017 |
Impact of the Commercialization of Three Generic Angiotensin II Receptor Blockers on Adverse Events in Quebec, Canada: A Population-Based Time Series Analysis.
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Databases, Factual; Drug Costs; Drug Substitution; Drugs, Generic; Emergency Service, Hospital; Humans; Hypertension; Losartan; Patient Admission; Patient Safety; Population Surveillance; Quebec; Referral and Consultation; Retrospective Studies; Risk Factors; Tetrazoles; Therapeutic Equivalency; Time Factors; Treatment Outcome; Valsartan | 2017 |
Angiotensin II Receptor-Neprilysin Inhibitor Sacubitril/Valsartan Improves Endothelial Dysfunction in Spontaneously Hypertensive Rats.
Topics: Aminobutyrates; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Endothelium, Vascular; Hypertension; KATP Channels; Male; Membrane Potentials; Mesenteric Artery, Superior; Neprilysin; Protease Inhibitors; Rats, Inbred SHR; Renin-Angiotensin System; Signal Transduction; Tetrazoles; Time Factors; Valsartan; Vasodilation; Vasodilator Agents | 2017 |
Advantages of sacubitril/valsartan beyond blood pressure control in arterial hypertension.
Topics: Aminobutyrates; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Drug Combinations; Essential Hypertension; Humans; Hypertension; Imidazoles; Tetrazoles; Valsartan | 2017 |
Aliskiren and valsartan in combination is a promising therapy for hypertensive renal injury in rats.
Topics: Amides; Animals; Antihypertensive Agents; Blood Pressure; Blood Urea Nitrogen; Creatinine; Drug Therapy, Combination; Enzyme Inhibitors; Fumarates; Hypertension; Kidney; Kidney Diseases; Male; NG-Nitroarginine Methyl Ester; Oxidative Stress; Proteinuria; Rats; Rats, Wistar; Valsartan | 2018 |
Sacubitril/valsartan instead of renin-angiotensin system inhibition alone: A step forward in resistant hypertension.
Topics: Aminobutyrates; Antihypertensive Agents; Biphenyl Compounds; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Hypertension; Neprilysin; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Tetrazoles; Treatment Outcome; Valsartan | 2018 |
Benefits and pitfalls of sacubitril/valsartan treatment in patients with hypertension.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Drug Combinations; Humans; Hypertension; Risk Assessment; Tetrazoles; Valsartan | 2018 |
Blood pressure variability and risk of cardiovascular events and death in patients with hypertension and different baseline risks.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Female; Heart Failure; Humans; Hypertension; Male; Middle Aged; Mortality; Myocardial Infarction; Prognosis; Proportional Hazards Models; Stroke; Valsartan | 2018 |
Nebivolol/Valsartan (Byvalson) for Hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Drug Combinations; Humans; Hypertension; Nebivolol; Valsartan | 2018 |
Combined Angiotensin Receptor-Neprilysin Inhibitors Improve Cardiac and Vascular Function Via Increased NO Bioavailability in Heart Failure.
Topics: Aminobutyrates; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Biphenyl Compounds; Disease Models, Animal; Drug Combinations; Heart Failure; Hypertension; Male; Myocardium; Natriuretic Peptides; Neprilysin; Nitric Oxide; Protease Inhibitors; Rats, Inbred SHR; Stroke Volume; Tetrazoles; Valsartan; Ventricular Function, Left | 2018 |
Comparison of real-world effectiveness between valsartan and non-RAS inhibitor monotherapy on the incidence of new diabetes in Chinese hypertensive patients: An electronic health recording system based study.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; China; Diabetic Angiopathies; Diuretics; Female; Humans; Hypertension; Male; Middle Aged; Valsartan | 2019 |
Effects of dual angiotensin type 1 receptor/neprilysin inhibition vs. angiotensin type 1 receptor inhibition on target organ injury in the stroke-prone spontaneously hypertensive rat.
Topics: Aminobutyrates; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Biphenyl Compounds; Blood Pressure; Cyclic GMP; Drug Combinations; Hypertension; Male; Neprilysin; Proteinuria; Rats; Rats, Inbred SHR; Stroke; Tetrazoles; Valsartan | 2018 |
Perindopril 3.5 mg/amlodipine 2.5 mg versus renin-angiotensin system inhibitor monotherapy as first-line treatment in hypertension: a combined analysis.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Female; Humans; Hypertension; Irbesartan; Male; Middle Aged; Perindopril; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Valsartan | 2018 |
Is sacubitril/valsartan safe for treatment of hypertension at any age?
Topics: Age Factors; Aminobutyrates; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Clinical Decision-Making; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Tetrazoles; Treatment Outcome; Valsartan | 2019 |
[THE COMBINED THERAPY IN HYPERTENSIVE PATIENTS WITH DYSLIPIDEMIA].
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Drug Combinations; Drug Therapy, Combination; Dyslipidemias; Fenofibrate; Humans; Hypertension; Hypolipidemic Agents; Middle Aged; Valsartan | 2018 |
Measuring Central or Peripheral Blood Pressure Levels? That is the Question in the Modern Clinical Practice of Hypertension.
Topics: Amlodipine; Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Nebivolol; Valsartan | 2018 |
Low-dose combination therapy to control sustained ambulatory hypertension-Basic principles and future directions.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Humans; Hypertension; Nifedipine; Valsartan; Vascular Stiffness | 2019 |
Angiotensin receptor neprilysin inhibition for the treatment of hypertension: the neglected child in cardiovascular pharmacotherapy.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Clinical Decision-Making; Drug Combinations; Humans; Hypertension; Neprilysin; Patient Selection; Protease Inhibitors; Renin-Angiotensin System; Tetrazoles; Treatment Outcome; Valsartan | 2019 |
Severe acute interstitial nephritis induced by valsartan: A case report.
Topics: Angiotensin II Type 1 Receptor Blockers; Creatinine; Female; Glucocorticoids; Humans; Hypertension; Middle Aged; Nephritis, Interstitial; Valsartan | 2019 |
Angiotensin converting enzyme and neprilysin inhibition alter pain response in dexhamethasone-induced hypertensive rats.
Topics: Aminobutyrates; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Dexamethasone; Disease Models, Animal; Drug Combinations; Hypertension; Male; Neprilysin; Pain; Pain Threshold; Peptidyl-Dipeptidase A; Ramipril; Rats; Rats, Wistar; Renin-Angiotensin System; Tetrazoles; Valsartan | 2019 |
Hypertension Hot Potato - Anatomy of the Angiotensin-Receptor Blocker Recalls.
Topics: Angiotensin II Type 1 Receptor Blockers; Dimethylnitrosamine; Drug Contamination; Drug Recalls; Humans; Hypertension; Irbesartan; Losartan; Nitrosamines; United States; United States Food and Drug Administration; Valsartan | 2019 |
AHU377+Valsartan (LCZ696) Modulates Renin-Angiotensin System (RAS) in the Cardiac of Female Spontaneously Hypertensive Rats Compared With Valsartan.
Topics: Aminobutyrates; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Drug Combinations; Female; Fibrosis; Gene Expression Regulation; Hypertension; Hypertrophy, Left Ventricular; Myocytes, Cardiac; Neprilysin; Oxidative Stress; Protease Inhibitors; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Signal Transduction; Tetrazoles; Valsartan; Vasodilation; Ventricular Function, Left; Ventricular Remodeling | 2019 |
The PARAGON Heart Failure trial - ongoing investigation of the angiotensin receptor antagonist/neprilysin inhibitor sacubitril/valsartan in heart failure patients with hypertension and preserved ejection fraction.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Clinical Trials as Topic; Drug Combinations; Heart Failure; Humans; Hypertension; Neprilysin; Stroke Volume; Tetrazoles; Treatment Outcome; Valsartan | 2019 |
Pill burden in hypertensive patients treated with single-pill combination therapy--an observational study.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Cost of Illness; Drug Combinations; Drug Therapy, Combination; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan | 2013 |
Amlodipine increases vitamin D levels more than valsartan in newly diagnosed hypertensive patients: pointing to an additional effect on bone metabolism or a novel marker of inflammation?
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Biomarkers; Bone Remodeling; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan; Vitamin D | 2013 |
Modelling of blood pressure outcomes in patients with and without established cardiovascular or renal disease following treatment with valsartan (the PREVIEW study).
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Belgium; Blood Pressure; Blood Pressure Determination; Cardiovascular Diseases; Chi-Square Distribution; Comparative Effectiveness Research; Female; General Practice; Humans; Hypertension; Kidney Diseases; Linear Models; Logistic Models; Male; Middle Aged; Odds Ratio; Prospective Studies; Risk Assessment; Risk Factors; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2013 |
[Effectiveness of antihypertensive treatment and control of blood pressure: is it improvable?].
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Drug Combinations; Drug Therapy, Combination; Humans; Hypertension; Oxadiazoles; Tetrazoles; Valsartan | 2013 |
Valsartan in the treatment of hypertension.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Retrospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan; Young Adult | 2013 |
Platelet activation in essential hypertension during exercise: pre- and post-treatment changes with an angiotensin II receptor blocker.
Topics: Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Carotid Intima-Media Thickness; Essential Hypertension; Exercise; Female; Humans; Hypertension; Male; Middle Aged; Platelet Activation; Tetrazoles; Valine; Valsartan | 2014 |
Research misconduct and scientific integrity: a call for a global forum.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Hypertension; Japan; Scientific Misconduct; Tetrazoles; Valine; Valsartan | 2013 |
Hierarchical modeling of patient and physician determinants of blood pressure outcomes in adherent vs nonadherent hypertensive patients: pooled analysis of 6 studies with 14,646 evaluable patients.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Cohort Studies; Female; Humans; Hypertension; Linear Models; Logistic Models; Male; Middle Aged; Models, Statistical; Patient Compliance; Physician-Patient Relations; Practice Patterns, Physicians'; Self Report; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2013 |
Scleroderma renal crisis in an elderly patient with overlap syndrome.
Topics: Aged; Biopsy; Enalapril; Female; Humans; Hypertension; Kidney; Renal Dialysis; Renal Insufficiency; Scleroderma, Systemic; Sjogren's Syndrome; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2013 |
Japanese Society of Hypertension official comment on valsartan papers.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Humans; Hypertension; Retraction of Publication as Topic; Scientific Misconduct; Societies; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2013 |
Maintaining goal blood pressures after switching from olmesartan to other angiotensin receptor blockers.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Drug Substitution; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Retrospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2013 |
Comparative effect of angiotensin II type I receptor blockers on serum uric acid in hypertensive patients with type 2 diabetes mellitus: a retrospective observational study.
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Imidazoles; Logistic Models; Losartan; Male; Middle Aged; Multivariate Analysis; Olmesartan Medoxomil; Retrospective Studies; Telmisartan; Tetrazoles; Treatment Outcome; Uric Acid; Valine; Valsartan | 2013 |
Plasma renin activity testing to guide triple antirenin system drug therapy in a patient with difficult-to-treat hypertension.
Topics: Aged; Amides; Antihypertensive Agents; Carbazoles; Carvedilol; Fumarates; Humans; Hypertension; Male; Propanolamines; Renin; Tetrazoles; Valine; Valsartan | 2014 |
Plasma renin activity testing to guide triple antirenin system drug therapy in a patient with difficult-to-treat hypertension.
Topics: Aged; Amides; Antihypertensive Agents; Blood Pressure; Carbazoles; Carvedilol; Drug Therapy, Combination; Fumarates; Humans; Hypertension; Male; Practice Guidelines as Topic; Precision Medicine; Predictive Value of Tests; Propanolamines; Renin; Renin-Angiotensin System; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2013 |
Effects of the angiotensin receptor blocker Valsartan (Valsacor®) on arterial pressure, indices of myocardial diastolic function and global longitudinal strain in patients with uncontrolled arterial hypertension.
Topics: Adult; Aged; Aged, 80 and over; Arterial Pressure; Drug Therapy, Combination; Echocardiography; Echocardiography, Doppler; Female; Follow-Up Studies; Heart Failure, Diastolic; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction; Tetrazoles; Valine; Valsartan | 2013 |
Examining the association of olmesartan and other angiotensin receptor blockers with overall and cause-specific mortality.
Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Cardiovascular Diseases; Cohort Studies; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Proportional Hazards Models; Registries; Retrospective Studies; Survival Rate; Taiwan; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2014 |
Valsartan-induced acute pancreatitis.
Topics: Angiotensin II Type 1 Receptor Blockers; Cholangiopancreatography, Endoscopic Retrograde; Cholangiopancreatography, Magnetic Resonance; Diagnosis, Differential; Humans; Hypertension; Male; Middle Aged; Pancreatitis, Acute Necrotizing; Sphincterotomy, Endoscopic; Tetrazoles; Valine; Valsartan | 2014 |
Renin-angiotensin system blockade and exercise-induced increase in aortic stiffness.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arteries; Essential Hypertension; Exercise; Female; Humans; Hypertension; Male; Tetrazoles; Valine; Valsartan; Vascular Stiffness | 2014 |
Exercise-induced pulse wave velocity changes in untreated patients with essential hypertension: the effect of an angiotensin receptor antagonist.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arteries; Blood Pressure; Blood Pressure Determination; Electrocardiography; Essential Hypertension; Exercise; Female; Humans; Hypertension; Male; Middle Aged; Pulse Wave Analysis; Tetrazoles; Valine; Valsartan; Vascular Stiffness | 2014 |
Clinical trial rigging: again!
Topics: Angina Pectoris; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Humans; Hypertension; Retraction of Publication as Topic; Scientific Misconduct; Stroke; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2014 |
Nebivolol and valsartan: useful treatment for hypertension?
Topics: Antihypertensive Agents; Benzopyrans; Ethanolamines; Female; Humans; Hypertension; Male; Nebivolol; Tetrazoles; Valine; Valsartan | 2014 |
Efficacy and safety of valsartan/amlodipine single-pill combination in patients with essential hypertension (PEAK LOW).
Topics: Administration, Oral; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Turkey; Valine; Valsartan | 2014 |
Valsartan prevents neointimal hyperplasia after carotid artery stenting by suppressing endothelial cell injuries.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Biomarkers; Calcium Channel Blockers; Carotid Arteries; Carotid Stenosis; Endothelial Cells; Female; Humans; Hyperplasia; Hypertension; Male; Prospective Studies; Stents; Tetrazoles; Treatment Outcome; Ultrasonography; Valine; Valsartan | 2015 |
Blood pressure variability, impaired autonomic function and vascular senescence in aged spontaneously hypertensive rats are ameliorated by angiotensin blockade.
Topics: Aging; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Autonomic Nervous System; Baroreflex; beta-Galactosidase; Blood Pressure; Drug Evaluation, Preclinical; Endothelium, Vascular; Hypertension; Imidazoles; Myocardium; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Norepinephrine; Organ Size; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reflex, Abnormal; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan; Vasodilation | 2014 |
Blood pressure control and satisfaction of hypertensive patients following a switch to combined drugs of an angiotensin receptor blocker and a calcium channel blocker in clinical practice of nephrology.
Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Azetidinecarboxylic Acid; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Drug Combinations; Drug Costs; Drug Substitution; Female; Humans; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Nephrology; Patient Satisfaction; Practice Patterns, Physicians'; Renal Insufficiency, Chronic; Retrospective Studies; Surveys and Questionnaires; Telmisartan; Tetrazoles; Valsartan | 2015 |
Comparative effects of valsartan in combination with cilnidipine or amlodipine on cardiac remodeling and diastolic dysfunction in Dahl salt-sensitive rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Dihydropyridines; Drug Evaluation, Preclinical; Drug Therapy, Combination; Heart; Hypertension; Hypertrophy, Left Ventricular; Male; Myocytes, Cardiac; Oxidative Stress; Rats, Inbred Dahl; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan; Ventricular Remodeling | 2015 |
Autoantibodies against β1 receptor and AT1 receptor in type 2 diabetes patients with left ventricular dilatation.
Topics: Aged; Antihypertensive Agents; Autoantibodies; Biomarkers; Diabetes Mellitus, Type 2; Dilatation, Pathologic; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Metoprolol; Middle Aged; Predictive Value of Tests; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, beta-1; Risk Factors; Sensitivity and Specificity; Tetrazoles; Valine; Valsartan | 2014 |
Elevated pressure causes endothelial dysfunction in mouse carotid arteries by increasing local angiotensin signaling.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Carotid Arteries; Endothelium, Vascular; Hydrazines; Hypertension; Indoles; Losartan; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Reactive Oxygen Species; Signal Transduction; Tetrazoles; Valine; Valsartan; Vasodilation | 2015 |
Should blood pressure medication be taken in the morning or evening?
Topics: Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Male; Valsartan | 2015 |
Comment on 'Time of administration important? Morning versus evening dosing of valsartan'.
Topics: Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Male; Valsartan | 2015 |
Comment on 'Time of administration important? Morning versus evening dosing of valsartan'.
Topics: Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Male; Valsartan | 2015 |
Real-world effectiveness of amlodipine/valsartan and amlodipine/valsartan/hydrochlorothiazide in high-risk patients and other subgroups.
Topics: Administration, Oral; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Asia; Blood Pressure; Calcium Channel Blockers; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Middle East; Prospective Studies; Tablets; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2015 |
Nano vesicular lipid carriers of angiotensin II receptor blocker: Anti-hypertensive and skin toxicity study in focus.
Topics: Acrylic Resins; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Ethanolamines; Hypertension; Liposomes; Polyethylene Glycols; Rats; Rats, Wistar; Skin Absorption; Valsartan | 2016 |
LCZ696, Angiotensin II Receptor-Neprilysin Inhibitor, Ameliorates High-Salt-Induced Hypertension and Cardiovascular Injury More Than Valsartan Alone.
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Circadian Rhythm; Cyclic GMP; Drug Combinations; Drug Evaluation, Preclinical; Endothelium, Vascular; Fibrosis; Heart; Hypertension; Inflammation; Male; Myocardium; Neprilysin; Oxidative Stress; Random Allocation; Rats, Inbred SHR; Sodium, Dietary; Tetrazoles; Valsartan; Vascular Remodeling | 2015 |
Noninferiority studies with multiple reference treatments.
Topics: Benzimidazoles; Blood Pressure; Equivalence Trials as Topic; Humans; Hypertension; Imidazoles; Oxadiazoles; Reference Standards; Research Design; Sample Size; Tetrazoles; Treatment Outcome; Valsartan | 2017 |
The ameliorated longevity and pharmacokinetics of valsartan released from a gel system of ultradeformable vesicles.
Topics: Administration, Topical; Animals; Drug Delivery Systems; Gels; Hypertension; Rats; Rats, Wistar; Skin Absorption; Valsartan | 2016 |
[Sleep apnea: RR lowering drugs need to be administered in the evening].
Topics: Amlodipine; Blood Pressure; Cross-Over Studies; Drug Chronotherapy; Drug Therapy, Combination; Humans; Hypertension; Sleep Apnea, Obstructive; Tetrazoles; Valine; Valsartan | 2015 |
Tetrahydrobiopterin reverse left ventricular hypertrophy and diastolic dysfunction through the PI3K/p-Akt pathway in spontaneously hypertensive rats.
Topics: Animals; Biopterins; Blood Pressure; Body Weight; Diastole; Hypertension; Hypertrophy, Left Ventricular; Male; Organ Size; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Valine; Valsartan | 2015 |
Telmisartan reduces atrial arrhythmia susceptibility through the regulation of RAS-ERK and PI3K-Akt-eNOS pathways in spontaneously hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Apoptosis; Arrhythmias, Cardiac; Atrial Remodeling; Benzimidazoles; Benzoates; Blood Pressure; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Heart Rate; Hypertension; Male; Myocytes, Cardiac; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; ras Proteins; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Telmisartan; Time Factors; Valsartan | 2015 |
Comparison of amlodipine/valsartan/hydrochlorothiazide single pill combination and free combination: adherence, persistence, healthcare utilization and costs.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Cohort Studies; Drug Combinations; Female; Hospitalization; Humans; Hydrochlorothiazide; Hypertension; Male; Medication Adherence; Middle Aged; Patient Acceptance of Health Care; Retrospective Studies; Valsartan | 2015 |
Clinical Effectiveness, Safety and Tolerability of Amlodipine/Valsartan in Hypertensive Patients: the Indonesian Subset of the EXCITE Study.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cough; Drug Combinations; Drug Substitution; Dyslipidemias; Edema; Female; Headache; Humans; Hypertension; Indonesia; Male; Medication Adherence; Middle Aged; Prospective Studies; Valsartan | 2015 |
Dyrk1A-ASF-CaMKIIδ Signaling Is Involved in Valsartan Inhibition of Cardiac Hypertrophy in Renovascular Hypertensive Rats.
Topics: Alternative Splicing; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiomegaly; Dyrk Kinases; Echocardiography; Hypertension; Male; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Valsartan | 2016 |
Vesicovascular reflexes in the spontaneously hypertensive rat.
Topics: Animals; Antihypertensive Agents; Atherosclerosis; Blood Pressure; Blood Vessels; Epinephrine; Hypertension; Male; Myocardium; Nifedipine; Norepinephrine; Pulse Wave Analysis; Rats; Rats, Inbred SHR; Rats, Wistar; Reflex; Valsartan; Vasodilator Agents | 2016 |
Hypertension - state of the art 2015.
Topics: Aminobutyrates; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Drug Combinations; Humans; Hypertension; Medication Adherence; Sodium, Dietary; Tetrazoles; Valsartan | 2016 |
Effect of angiotensin receptor blockade on central aortic systolic blood pressure in hypertensive Asians measured using radial tonometry: an open prospective cohort study.
Topics: Adult; Angiotensin Receptor Antagonists; Aorta; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diastole; Female; Humans; Hypertension; Male; Manometry; Middle Aged; Prospective Studies; Receptors, Angiotensin; Systole; Valsartan; Young Adult | 2016 |
The velocity of antihypertensive effects of seven angiotensin II receptor blockers determined by home blood pressure measurements.
Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Blood Pressure Determination; Female; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Oxadiazoles; Self Care; Telmisartan; Tetrazoles; Time Factors; Valsartan | 2016 |
Influence of initial angiotensin receptor blockers on treatment persistence in uncomplicated hypertension: A nation-wide population-based study.
Topics: Acrylates; Adult; Aged; Angiotensin Receptor Antagonists; Biphenyl Compounds; Cohort Studies; Female; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Medication Adherence; Middle Aged; Outcome Assessment, Health Care; Republic of Korea; Retrospective Studies; Risk Factors; Tetrazoles; Thiophenes; Valsartan | 2016 |
Effect of Valsartan on Cerebellar Adrenomedullin System Dysregulation During Hypertension.
Topics: Adrenomedullin; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Catalase; Cerebellum; Disease Models, Animal; Glutathione Peroxidase; Hypertension; Male; Random Allocation; Rats, Inbred SHR; Rats, Inbred WKY; Receptor Activity-Modifying Protein 1; Receptor Activity-Modifying Protein 2; Receptor Activity-Modifying Protein 3; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Valsartan | 2017 |
The effect of fixed-dose combination of valsartan and amlodipine on nighttime blood pressure in patients with non-dipper hypertension.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cohort Studies; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Valsartan | 2016 |
On the top of ARB N/L type Ca channel blocker leads to less elevation of aldosterone.
Topics: Aged; Aldosterone; Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Renin-Angiotensin System; Valsartan | 2016 |
Influence of Age and Race on 24-Hour Ambulatory Blood Pressure Responses to Valsartan, Hydrochlorothiazide, and Their Combination: Implications for Clinical Practice.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antihypertensive Agents; Black or African American; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Treatment Outcome; Valsartan; White People; Young Adult | 2017 |
Byvalson--a beta blocker/ARB combination for hypertension.
Topics: Adrenergic beta-1 Receptor Agonists; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Drug Administration Schedule; Drug Combinations; Drug Interactions; Humans; Hypertension; Nebivolol; Treatment Outcome; Valsartan | 2016 |
Long-Term Angiotensin II Receptor Blockade Limits Hypertension, Aortic Dysfunction, and Structural Remodeling in a Rat Model of Chronic Kidney Disease.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Aortic Diseases; Blood Pressure; Cathepsin D; Cathepsin L; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hypertension; Kidney; Male; Matrix Metalloproteinase 9; NF-kappa B; Polycystic Kidney Diseases; Rats, Inbred Lew; Renal Insufficiency, Chronic; Time Factors; Valsartan; Vascular Remodeling; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2016 |
Sacubitril/valsartan in the treatment of arterial hypertension: an unaccomplished promise?
Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Drug Combinations; Humans; Hypertension; Tetrazoles; Valsartan | 2017 |
Role of the renin-angiotensin-aldosterone system in collecting duct-derived endothelin-1 regulation of blood pressure.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Base Sequence; Blood Pressure; DNA Primers; Endothelin-1; Female; Hypertension; Kidney Tubules, Collecting; Male; Mice; Mice, Knockout; Mineralocorticoid Receptor Antagonists; Renin; Renin-Angiotensin System; Spironolactone; Tetrazoles; Valine; Valsartan | 2008 |
Can changing antihypertensive administration time alone reduce the risk for CVD in nondipper patients with CKD?
Topics: Antihypertensive Agents; Cardiovascular Diseases; Chronotherapy; Follow-Up Studies; Humans; Hypertension; Incidence; Renal Insufficiency, Chronic; Risk Assessment; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2008 |
Antihypertensive therapy in children: implications for future studies.
Topics: Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Hypertension; Male; Randomized Controlled Trials as Topic; Severity of Illness Index; Tetrazoles; Valine; Valsartan | 2008 |
Significance of pulsatility of brachial artery pressure for blood pressure control.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Brachial Artery; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Pulsatile Flow; Pulse; Tetrazoles; Valine; Valsartan | 2008 |
Application in the STRATHE trial of a score system to compare the efficacy and the tolerability of different therapeutic strategies in the management of hypertension.
Topics: Amlodipine; Antihypertensive Agents; Atenolol; Double-Blind Method; Drug Therapy, Combination; France; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Losartan; Perindopril; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Long-term effects of angiotensin II receptor blockade with valsartan on carotid arterial stiffness and hemodynamic alterations in patients with essential hypertension.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Blood Flow Velocity; Carotid Artery, Common; Elasticity; Female; Humans; Hypertension; Male; Prospective Studies; Tetrazoles; Time Factors; Treatment Outcome; Tunica Media; Ultrasonography; Valine; Valsartan; Vascular Resistance | 2008 |
Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation.
Topics: Acetophenones; Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Astrocytes; Blood Pressure; Cerebral Cortex; Enzyme Activation; Enzyme Inhibitors; Humans; Hydralazine; Hypertension; Inflammation; Male; NADPH Oxidases; Neurons; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Sodium Chloride; Stroke; Tetrazoles; Valine; Valsartan | 2008 |
Adherence with multiple-combination antihypertensive pharmacotherapies in a US managed care database.
Topics: Adolescent; Adult; Age Factors; Aged; Amlodipine; Antihypertensive Agents; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Insurance Claim Review; Male; Managed Care Programs; Middle Aged; Patient Compliance; Tetrazoles; United States; Valine; Valsartan | 2008 |
Cost-effectiveness analysis: controlled-release nifedipine and valsartan combination therapy in patients with essential hypertension: the adalat CR and valsartan cost-effectiveness combination (ADVANCE-Combi) study.
Topics: Amlodipine; Cost-Benefit Analysis; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Japan; Nifedipine; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2008 |
Valsartan improves L-NAME-exacerbated cardiac fibrosis with TGF-ß inhibition and apoptosis induction in spontaneously hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Caspase 3; Fibrosis; Hypertension; Male; Myocardium; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred SHR; RNA; Tetrazoles; Transforming Growth Factor beta; Valine; Valsartan; Ventricular Remodeling | 2008 |
Effects of 12-month valsartan therapy on glycation and oxidative stress markers in type 2 diabetic subjects with hypertension.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adiponectin; Aged; Albuminuria; Antihypertensive Agents; Aryldialkylphosphatase; Biomarkers; C-Reactive Protein; Carotid Arteries; Diabetes Mellitus, Type 2; Dinoprost; Female; Glycation End Products, Advanced; Humans; Hypertension; Male; Middle Aged; Oxidative Stress; Tetrazoles; Valine; Valsartan | 2008 |
Primary CNS lymphoma presenting as fever of unknown origin.
Topics: Antihypertensive Agents; Antineoplastic Agents; Antitubercular Agents; Aspirin; Brain Neoplasms; Cranial Irradiation; Diagnosis, Differential; Fatal Outcome; Fever of Unknown Origin; Humans; Hypertension; Indapamide; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Tetrazoles; Tuberculosis; Valine; Valsartan | 2009 |
Effectiveness of add-on therapy with amlodipine in hypertensive patients receiving valsartan.
Topics: Adolescent; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cohort Studies; Databases, Factual; Drug Resistance; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Retrospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan; Young Adult | 2008 |
Chronotherapeutic drug delivery for early morning surge in blood pressure: a programmable delivery system.
Topics: Blood Pressure; Drug Chronotherapy; Drug Delivery Systems; Hypertension; Solubility; Tablets, Enteric-Coated; Tetrazoles; Valine; Valsartan | 2009 |
Triple fixed-dose combination therapy: back to the past.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Diastole; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Systole; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Silica in oral drugs as a possible sarcoidosis-inducing antigen.
Topics: Administration, Oral; Antigens; Antihypertensive Agents; Bisoprolol; Causality; Chemistry, Pharmaceutical; Doxazosin; Humans; Hypertension; Male; Middle Aged; Pharmaceutical Vehicles; Sarcoidosis, Pulmonary; Silicon Dioxide; Tetrazoles; Valine; Valsartan | 2009 |
Exforge HCT.
Topics: Amlodipine; Amlodipine, Valsartan Drug Combination; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Drug Combinations; Drug Costs; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Valine; Valsartan | 2009 |
Re: Efficacy and safety of the single pill combination of amlodipine 10 mg plus valsartan 160 mg in hypertensive patients not controlled by amlodipine 10 mg plus olmesartan 20 mg in free combination.
Topics: Amlodipine; Antihypertensive Agents; Clinical Trials as Topic; Dosage Forms; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Tablets; Tetrazoles; Treatment Failure; Treatment Outcome; Valine; Valsartan | 2009 |
Significance of angiotensin II receptor blockers with high affinity to angiotensin II type 1 receptors for vascular protection in rats.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Carotid Arteries; Hypertension; Imidazoles; Immunohistochemistry; In Vitro Techniques; Male; Muscle Relaxation; NADPH Oxidases; Peptidyl-Dipeptidase A; Protective Agents; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Renin; Reverse Transcriptase Polymerase Chain Reaction; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Tetrazoles; Valine; Valsartan; Vascular Diseases | 2009 |
AT(1) receptor blockers increase insulin-like growth factor-I production by stimulating sensory neurons in spontaneously hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Ganglia, Spinal; Hypertension; Imidazoles; Insulin-Like Growth Factor I; Kidney; Losartan; Male; Myocardium; Nifedipine; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; RNA, Messenger; Sensory Receptor Cells; Telmisartan; Tetrazoles; Valine; Valsartan; Vasodilator Agents | 2009 |
Very high doses of valsartan provide renoprotection independently of blood pressure in a type 2 diabetic nephropathy rat model.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Hypertension; Linear Models; Male; Proteinuria; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Valine; Valsartan | 2009 |
Angiotensin receptor blockers: baseline therapy in hypertension?
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Humans; Hypertension; Risk Factors; Tetrazoles; Valine; Valsartan | 2009 |
Angiotensin II receptor blocker, valsartan, increases myocardial blood volume and regresses hypertrophy in hypertensive patients.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Blood Volume; Case-Control Studies; Echocardiography, Doppler; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2009 |
The role of baseline blood pressure in guiding treatment choice: a secondary analysis of the use of valsartan/hydrochlorothiazide as initial therapy in hypertensive adults in a randomized, double-blind, placebo-controlled trial.
Topics: Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Randomized Controlled Trials as Topic; Retrospective Studies; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
The surge of Japanese studies supporting the use of angiotensin receptor blockers in hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Humans; Hypertension; Japan; Tetrazoles; Valine; Valsartan | 2009 |
Amlodipine/valsartan/hydrochlorothiazide: fixed-dose combination in hypertension.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials, Phase III as Topic; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Valine; Valsartan | 2009 |
Effects of valsartan on morbidity and mortality in uncontrolled hypertensive patients with high cardiovascular risks: KYOTO HEART Study.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Humans; Hypertension; Stroke; Tetrazoles; Valine; Valsartan | 2010 |
HOTLINE III: KYOTO shows ARBs have efficacy in Asian populations.
Topics: Antihypertensive Agents; Humans; Hypertension; Japan; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2009 |
Economic impact of switching from valsartan to other angiotensin receptor blockers in patients with hypertension.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Cost-Benefit Analysis; Deductibles and Coinsurance; Drugs, Generic; Fees, Pharmaceutical; Female; Health Care Costs; Health Services; Humans; Hypertension; Male; Matched-Pair Analysis; Medication Adherence; Middle Aged; Tetrazoles; United States; Valine; Valsartan | 2010 |
Challenges of therapeutic substitution of drugs for economic reasons: focus on CVD prevention.
Topics: Angiotensin II Type 1 Receptor Blockers; Cost Control; Cost-Benefit Analysis; Drugs, Generic; Europe; Fees, Pharmaceutical; Health Care Costs; Humans; Hypertension; Medication Adherence; Patient Preference; Tetrazoles; Therapeutic Equivalency; United Kingdom; United States; Valine; Valsartan | 2010 |
Blood pressure lowering with valsartan is associated with maintenance of cerebral blood flow and cerebral perfusion reserve in hypertensive patients with cerebral small vessel disease.
Topics: Acetazolamide; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Cerebral Arteries; Cerebrovascular Circulation; Diuretics; Female; Humans; Hypertension; Intracranial Arteriosclerosis; Male; Microcirculation; Middle Aged; Nerve Fibers, Myelinated; Positron-Emission Tomography; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Blood-pressure reduction with LCZ696.
Topics: Aminobutyrates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Drug Combinations; Humans; Hypertension; Neprilysin; Tetrazoles; Valine; Valsartan | 2010 |
[Effect of valsartan on ultrastructure in the brain tissue and expression of Klotho gene in spontaneously hypertensive rats].
Topics: Animals; Antihypertensive Agents; Brain; Glucuronidase; Hypertension; Intercellular Adhesion Molecule-1; Klotho Proteins; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Valine; Valsartan; Vascular Cell Adhesion Molecule-1 | 2010 |
Role of valsartan, amlodipine and hydrochlorothiazide fixed combination in blood pressure control: an update.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Valine; Valsartan | 2010 |
Economic evaluation of irbesartan in combination with hydrochlorothiazide in the treatment of hypertension in Greece.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Cardiovascular Diseases; Clinical Trials as Topic; Cost-Benefit Analysis; Drug Combinations; Female; Greece; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Losartan; Male; Markov Chains; Middle Aged; Models, Economic; Quality of Life; Sex Factors; Tetrazoles; Valine; Valsartan | 2011 |
Trial watch: dual inhibition shows promise in hypertension.
Topics: Aminobutyrates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Clinical Trials, Phase II as Topic; Drug Combinations; Humans; Hypertension; Neprilysin; Tetrazoles; Valsartan | 2010 |
Pharmaceutical composition of valsartan: beta-cyclodextrin: physico-chemical characterization and anti-hypertensive evaluation.
Topics: Animals; Antihypertensive Agents; Cyclodextrins; Hypertension; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Rats; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Tetrazoles; Valine; Valsartan | 2010 |
Comparison of amlodipine/valsartan fixed-dose combination therapy and conventional therapy.
Topics: Aged; Amlodipine; Antihypertensive Agents; Drug Combinations; Female; Health Services; Humans; Hypertension; Male; Medical Audit; Middle Aged; Outcome Assessment, Health Care; Retrospective Studies; Tetrazoles; Valine; Valsartan | 2010 |
Chart review of patients on valsartan-based single-pill combinations vs. ARB-based free combinations for BP goal achievement.
Topics: Adult; Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Comorbidity; Down-Regulation; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Retrospective Studies; Tablets; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Effect of valsartan on the incidence of diabetes.
Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Confounding Factors, Epidemiologic; Diabetes Mellitus, Type 2; Diuretics; Humans; Hypertension; Incidence; Tetrazoles; Valine; Valsartan | 2010 |
Therapeutic implications of high-dose angiotensin receptor blocker monotherapy in mild-to-moderate hypertensive patients.
Topics: Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Dose-Response Relationship, Drug; Humans; Hypertension; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Local angiotensin II aggravates cardiac remodeling in hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Collagen; Desoxycorticosterone; Dinoprost; Disease Models, Animal; Heart Rate; Hypertension; Male; Membrane Glycoproteins; Mice; Mice, Transgenic; Myocardium; Myocytes, Cardiac; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta1; Valine; Valsartan | 2010 |
The N-type and L-type calcium channel blocker cilnidipine suppresses renal injury in Dahl rats fed a high-salt diet.
Topics: Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; Disease Models, Animal; Drug Therapy, Combination; Glomerulonephritis; Hypertension; Kidney; Kidney Diseases; Male; Organ Size; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Tetrazoles; Time Factors; Valine; Valsartan | 2010 |
Fosinopril and valsartan intervention in gene expression of Klotho, MMP-9, TIMP-1, and PAI-1 in the kidney of spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Fibrosis; Fosinopril; Glucuronidase; Hypertension; Kidney; Klotho Proteins; Male; Matrix Metalloproteinase 9; Plasminogen Activator Inhibitor 1; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Tetrazoles; Tissue Inhibitor of Metalloproteinase-1; Valine; Valsartan | 2010 |
[CCB uptitration is superior to ARB uptitration in CKD patients who do not reach target blood pressure with ARB/CCB combined therapy].
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Calcium Channel Blockers; Chronic Disease; Drug Therapy, Combination; Glomerular Filtration Rate; Hypertension; Kidney Diseases; Nifedipine; Tetrazoles; Time Factors; Valine; Valsartan | 2010 |
Determinants of masked hypertension in hypertensive patients treated in a primary care setting.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Cardiovascular Diseases; Comorbidity; Diabetes Complications; Drug Therapy, Combination; Dyslipidemias; Female; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Male; Masked Hypertension; Middle Aged; Obesity; Prevalence; Primary Health Care; Quebec; Risk; Tetrazoles; Valine; Valsartan; White Coat Hypertension | 2012 |
Temporary treatment with AT1 receptor blocker, valsartan, from early stage of hypertension prevented vascular remodeling.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Arteries; Blood Vessels; Disease Models, Animal; Hydralazine; Hypertension; Mice; Mice, Inbred C57BL; NADPH Oxidases; Neointima; Oxidative Stress; Renin; Tetrazoles; Valine; Valsartan | 2011 |
Telmisartan provides better renal protection than valsartan in a rat model of metabolic syndrome.
Topics: Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Pressure; Body Weight; Dietary Fats; Disease Models, Animal; Hypertension; Kidney Diseases; Male; Metabolic Syndrome; PPAR gamma; Rats; Rats, Inbred SHR; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
Efficacy, safety, and tolerability of valsartan/hydrochlorothiazide in Asian patients with essential hypertension.
Topics: Adult; Antihypertensive Agents; Asia; Asian People; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Pacific Islands; Tetrazoles; Valine; Valsartan; Young Adult | 2011 |
Amlodipine + valsartan + hydrochlorothiazide. A 3-drug fixed-dose combination for hypertension: too many drawbacks.
Topics: Amlodipine; Antihypertensive Agents; Drug Combinations; Drug Packaging; Humans; Hydrochlorothiazide; Hypertension; Medication Errors; Tetrazoles; Valine; Valsartan | 2011 |
[Correction of aldosterone level as marker of RAAS dysfunction in patients with arterial hypertension degree II-III and chronic kidney diseases].
Topics: Aged; Aldosterone; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biomarkers; Drug Therapy, Combination; Enalapril; Female; Fumarates; Humans; Hypertension; Indapamide; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Randomized Controlled Trials as Topic; Renal Insufficiency, Chronic; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2011 |
Emerging benefits of AT1 receptor antagonists with pleiotropic anti-inflammatory activity.
Topics: Animals; Benzimidazoles; Benzoates; Hypertension; Kidney Diseases; Male; Metabolic Syndrome; Telmisartan; Tetrazoles; Valine; Valsartan | 2011 |
Irbesartan prevents metabolic syndrome in rats via activation of peroxisome proliferator-activated receptor γ.
Topics: Adiponectin; Adipose Tissue; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Gene Expression Regulation; Glucose Transporter Type 4; Hypertension; Hypertriglyceridemia; Hypoglycemic Agents; Insulin Resistance; Irbesartan; Male; Metabolic Syndrome; Pioglitazone; PPAR gamma; Rats; Rats, Inbred SHR; RNA, Messenger; Tetrazoles; Thiazolidinediones; Valine; Valsartan | 2011 |
Role of angiotensin-(1-7) in rostral ventrolateral medulla in blood pressure regulation via sympathetic nerve activity in Wistar-Kyoto and spontaneous hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Peptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System; Tetrazoles; Valine; Valsartan | 2011 |
Effects of multiple factorial intervention on ambulatory BP profile and renal function in hypertensive type 2 diabetic patients with overt nephropathy - a pilot study.
Topics: Albuminuria; Anticholesteremic Agents; Antihypertensive Agents; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Comorbidity; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Fatty Acids, Monounsaturated; Female; Fluvastatin; Glomerular Filtration Rate; Heart Rate; Humans; Hypertension; Indoles; Kidney; Lipids; Male; Middle Aged; Pilot Projects; Prospective Studies; Regression Analysis; Tetrazoles; Valine; Valsartan | 2011 |
Formulation and optimization of nanotransfersomes using experimental design technique for accentuated transdermal delivery of valsartan.
Topics: Administration, Cutaneous; Animals; Antihypertensive Agents; Disease Models, Animal; Drug Delivery Systems; Humans; Hypertension; Liposomes; Nanospheres; Particle Size; Rats; Rats, Wistar; Tetrazoles; Valine; Valsartan | 2012 |
[The significance of generic valsartan in the treatment of patients].
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Drugs, Generic; Humans; Hypertension; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2011 |
Comparison of real-world adherence, healthcare resource utilization and costs for newly initiated valsartan/amlodipine single-pill combination versus angiotensin receptor blocker/calcium channel blocker free-combination therapy.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Drug Combinations; Female; Health Care Costs; Health Services; Humans; Hypertension; Male; Medication Adherence; Middle Aged; Retrospective Studies; Tetrazoles; United States; Valine; Valsartan | 2011 |
Beneficial effects of combination of valsartan and amlodipine on salt-induced brain injury in hypertensive rats.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Brain; Calcium Channel Blockers; Calcium Channels; Carotid Arteries; Drug Therapy, Combination; Endothelial Cells; Hypertension; Hypoxia-Ischemia, Brain; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Random Allocation; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Sodium Chloride, Dietary; Tetrazoles; Tyrosine; Valine; Valsartan | 2011 |
Cardiovascular effects of the combination of levosimendan and valsartan in hypertensive Dahl/Rapp rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Cardiomegaly; Cardiovascular Diseases; Diet, Sodium-Restricted; Echocardiography; Heart; Heart Failure; Heart Rate; Hydrazones; Hypertension; Kidney; Male; Myocytes, Cardiac; Pyridazines; Rats; Rats, Inbred Dahl; RNA, Messenger; Simendan; Sodium Chloride, Dietary; Sodium, Dietary; Tetrazoles; Valine; Valsartan; Vasodilator Agents; Ventricular Remodeling | 2011 |
Patient- and physician-level determinants of blood pressure response to treatment in normal weight and overweight patients (the PREVIEW study).
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Belgium; Blood Pressure; Body Mass Index; Body Weight; Clinical Competence; Female; Guideline Adherence; Humans; Hypertension; Linear Models; Logistic Models; Male; Medication Adherence; Middle Aged; Odds Ratio; Overweight; Practice Guidelines as Topic; Practice Patterns, Physicians'; Prospective Studies; Risk Factors; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2013 |
Modelling of blood pressure and total cardiovascular risk outcomes after second-line valsartan therapy: the BSCORE study.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Linear Models; Logistic Models; Male; Middle Aged; Odds Ratio; Prospective Studies; Risk Assessment; Risk Factors; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2011 |
Cardiovascular protection with danshensu in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Body Weight; Cardiotonic Agents; Cardiovascular System; Chronic Disease; Drug Administration Schedule; Drug Evaluation, Preclinical; Heart; Heart Function Tests; Hypertension; Lactates; Large-Conductance Calcium-Activated Potassium Channels; Male; Mesenteric Arteries; Molecular Targeted Therapy; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type II; Patch-Clamp Techniques; Phytotherapy; Plant Preparations; Plant Roots; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Salvia miltiorrhiza; Tetrazoles; Valine; Valsartan | 2011 |
Evolutionary cost analysis of valsartan initiation among patients with hypertension: a time series approach.
Topics: Adolescent; Adult; Antihypertensive Agents; Costs and Cost Analysis; Databases, Factual; Female; Humans; Hypertension; Male; Middle Aged; Retrospective Studies; Tetrazoles; United States; Valine; Valsartan; Young Adult | 2012 |
Comparison of the efficacy and safety of single-pill fixed-dose combinations of losartan/hydrochlorothiazide and valsartan/hydrochlorothiazide in patients with hypertension (SALT-VAT study).
Topics: Aged; Blood Pressure; Drug Combinations; Drug Substitution; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
Blood pressure outcomes in patients receiving angiotensin II receptor blockers in primary care: a comparative effectiveness analysis from electronic medical record data.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Black or African American; Blood Pressure; Diabetes Mellitus; Electronic Health Records; Female; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Obesity; Primary Health Care; Retrospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan; White People; Young Adult | 2011 |
Cost-effectiveness analysis of valsartan versus losartan and the effect of switching.
Topics: Antihypertensive Agents; Cardiovascular Diseases; Cost-Benefit Analysis; Drug Substitution; Fees, Pharmaceutical; Humans; Hypertension; Insurance, Health, Reimbursement; Losartan; Outcome Assessment, Health Care; Quality-Adjusted Life Years; Tetrazoles; United States; Valine; Valsartan | 2012 |
The effect of valsartan on left ventricular myocardial functions in hypertensive patients with left ventricular hypertrophy.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomechanical Phenomena; Blood Pressure; Echocardiography, Doppler; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardial Contraction; Prospective Studies; Recovery of Function; Tetrazoles; Time Factors; Treatment Outcome; Turkey; Valine; Valsartan; Ventricular Function, Left | 2012 |
Valsartan, an angiotensin receptor blocker treats sexual dysfunction in a female hypertensive: a case report.
Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Middle Aged; Orgasm; Sexual Dysfunction, Physiological; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
Valsartan: in children and adolescents with hypertension.
Topics: Adolescent; Antihypertensive Agents; Blood Pressure; Child; Enalapril; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2012 |
Aquaporin changes during diabetic retinopathy in rats are accelerated by systemic hypertension and are linked to the renin-angiotensin system.
Topics: Adrenergic beta-1 Receptor Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Aquaporins; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glial Fibrillary Acidic Protein; Hypertension; Metoprolol; Nerve Fibers; Neuroglia; Rats; Rats, Inbred WKY; Renin-Angiotensin System; Retina; Tetrazoles; Valine; Valsartan | 2012 |
Comparative efficacy of aliskiren/valsartan vs valsartan in nocturnal dipper and nondipper hypertensive patients: a pooled analysis.
Topics: Adult; Aged; Amides; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fumarates; Humans; Hypertension; Male; Middle Aged; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2012 |
The effect of valsartan and nebivolol treatment on ADMA and pentraxin-3 levels in hypertensive patients.
Topics: Adult; Antihypertensive Agents; Arginine; Benzopyrans; C-Reactive Protein; Ethanolamines; Female; Humans; Hypertension; Male; Middle Aged; Nebivolol; Serum Amyloid P-Component; Tetrazoles; Valine; Valsartan | 2012 |
Does response of RAS blockade on serum K+ levels influence its glycemic-mitigating response when combined with hydrochlorothiazide?
Topics: Aged; Antihypertensive Agents; Blood Glucose; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypertension; Insulin; Male; Middle Aged; Obesity, Abdominal; Outpatients; Postprandial Period; Potassium; Renin-Angiotensin System; Statistics as Topic; Tetrazoles; Valine; Valsartan | 2012 |
A comparison of the effects of fixed dose vs. single-agent combinations on 24-h blood pressure variability.
Topics: Aged; Amlodipine; Amlodipine, Valsartan Drug Combination; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Time Factors; Valine; Valsartan | 2012 |
Additive effects of cilnidipine and angiotensin II receptor blocker in preventing the progression of diabetic nephropathy in diabetic spontaneously hypertensive rats.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dihydropyridines; Disease Progression; Drug Therapy, Combination; Glomerulonephritis; Glucagon; Glucose Transporter Type 1; Glycated Hemoglobin; Glycogen; Hypertension; Kidney; Male; Norepinephrine; Proteinuria; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta1; Valine; Valsartan | 2013 |
Improving drug adherence using fixed combinations caused beneficial treatment outcomes and decreased health-care costs in patients with hypertension.
Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Health Care Costs; Humans; Hypertension; Male; Medication Adherence; Middle Aged; Prospective Studies; Retrospective Studies; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2013 |
The occurrence rate of cerebrovascular and cardiac events in patients receiving antihypertensive therapy from the post-marketing surveillance data for valsartan in Japan (J-VALID).
Topics: Aged; Angina Pectoris; Angiotensin Receptor Antagonists; Antihypertensive Agents; Cardiovascular Diseases; Cerebral Hemorrhage; Cerebral Infarction; Cerebrovascular Disorders; Female; Health Surveys; Heart Failure; Humans; Hypertension; Incidence; Japan; Male; Middle Aged; Myocardial Infarction; Product Surveillance, Postmarketing; Prospective Studies; Registries; Retrospective Studies; Stroke; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2013 |
Hypertension and the J-curve phenomenon: implications for tight blood pressure control.
Topics: Antihypertensive Agents; Cardiovascular Diseases; Cerebrovascular Disorders; Female; Humans; Hypertension; Male; Product Surveillance, Postmarketing; Tetrazoles; Valine; Valsartan | 2013 |
[Antihypertensive therapy and dynamics of vascular wall rigidity in elderly patients with non-valvular atrial fibrillation].
Topics: Aged; Ankle Brachial Index; Anticholesteremic Agents; Antihypertensive Agents; Arterial Pressure; Arteries; Atrial Fibrillation; Combined Modality Therapy; Drug Monitoring; Female; Fluorobenzenes; Humans; Hypertension; Male; Myocardial Infarction; Perindopril; Pulse Wave Analysis; Pyrimidines; Rosuvastatin Calcium; Stroke; Sulfonamides; Tetrazoles; Treatment Outcome; Ultrasonography, Doppler, Duplex; Valine; Valsartan; Vascular Resistance | 2012 |
Hemodynamic and hormonal changes to dual renin-angiotensin system inhibition in experimental hypertension.
Topics: Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Fumarates; Heart Rate; Hemodynamics; Hypertension; Kidney; Male; Rats; Renin; Renin-Angiotensin System; Telemetry; Tetrazoles; Valine; Valsartan | 2013 |
Comparative efficacy of irbesartan/ hydrochlorothiazide and valsartan/hydrochlorothiazide combination in lowering blood pressure: a retrospective observational study in Oman.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diabetes Complications; Diabetes Mellitus; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Oman; Retrospective Studies; Tetrazoles; Valine; Valsartan | 2013 |
Exfoliative esophagitis in a patient with metastatic renal cell carcinoma during sunitinib treatment.
Topics: Amlodipine; Antihypertensive Agents; Antineoplastic Agents; Aspirin; Carcinoma, Renal Cell; Cyclooxygenase 2 Inhibitors; Esophagitis; Humans; Hypertension; Indoles; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Nephrectomy; Pyrroles; Sunitinib; Tetrazoles; Valine; Valsartan | 2013 |
[24-hour arterial hypertension profile and heart rhythm variability in patients with arterial hypertension and NIDDM].
Topics: Angiotensin-Converting Enzyme Inhibitors; Circadian Rhythm; Diabetes Mellitus, Type 2; Enalapril; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2002 |
[Fixed combination of AT1 blocker and diuretic. Stroke preventive combination for hypertension].
Topics: Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Stroke; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2002 |
Ventrolateral medulla AT1 receptors support blood pressure in hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Brain Stem; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hypertension; Injections; Kynurenic Acid; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents | 2002 |
Tissue angiotensin II during progression or ventricular hypertrophy to heart failure in hypertensive rats; differential effects on PKC epsilon and PKC beta.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Disease Progression; Echocardiography; Enzyme Activation; Heart Failure; Hypertension; Male; Myocardium; Organ Size; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-epsilon; Protein Transport; Rats; Rats, Inbred Dahl; Stress, Mechanical; Tetrazoles; Valine; Valsartan; Ventricular Function, Left | 2002 |
The safety of valsartan: results of a postmarketing surveillance study on 12881 patients in England.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Cohort Studies; Dizziness; Drug Monitoring; England; Female; Headache; Humans; Hypertension; Male; Middle Aged; Nausea; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Product Surveillance, Postmarketing; Tetrazoles; Valine; Valsartan | 2002 |
Irbesartan substitution for valsartan or losartan in treating hypertension.
Topics: Aged; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Female; Humans; Hypertension; Irbesartan; Losartan; Male; Middle Aged; Retrospective Studies; Tetrazoles; Therapeutic Equivalency; Valine; Valsartan | 2002 |
Prolonged treatment with the AT1 receptor blocker, valsartan, increases small and large artery compliance in uncomplicated essential hypertension.
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Elasticity; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan; Vascular Resistance | 2002 |
[Lowering blood pressure with sartans. Are there differences?].
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Cross-Over Studies; Humans; Hypertension; Losartan; Randomized Controlled Trials as Topic; Telmisartan; Tetrazoles; Valine; Valsartan | 2002 |
Disparate effects of angiotensin II antagonists and calcium channel blockers on albuminuria in experimental diabetes and hypertension: potential role of nephrin.
Topics: Albuminuria; Amlodipine; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Drug Therapy, Combination; Hypertension; Kidney Glomerulus; Male; Membrane Proteins; Proteins; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Sclerosis; Systole; Tetrazoles; Valine; Valsartan; Verapamil | 2003 |
Aminopeptidase activity in renovascular hypertension.
Topics: Aminopeptidases; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Down-Regulation; Heart Atria; Heart Ventricles; Hypertension; Hypertension, Renovascular; Lung; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan | 2003 |
Valsartan-induced hepatotoxicity in a HBs-Ag-Positive patient.
Topics: Antihypertensive Agents; Chemical and Drug Induced Liver Injury; Female; Hepatitis B Surface Antigens; Humans; Hypertension; Middle Aged; Tetrazoles; Valine; Valsartan | 2003 |
Reversal of interstitial fibroblast hyperplasia via apoptosis in hypertensive rat heart with valsartan or enalapril.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Apoptosis; Enalapril; Fibroblasts; Heart Ventricles; Hyperplasia; Hypertension; Hypertrophy, Left Ventricular; In Situ Nick-End Labeling; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Valine; Valsartan | 2003 |
[High dose sartan plus thiazide. Power duo in hypertension].
Topics: Antihypertensive Agents; Dose-Response Relationship, Drug; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Valine; Valsartan | 2003 |
Ventrolateral medulla AT1 receptors support arterial pressure in Dahl salt-sensitive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Hypertension; Male; Medulla Oblongata; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Sodium Chloride; Tetrazoles; Valine; Valsartan | 2003 |
Cardiovascular hypertrophy in diabetic spontaneously hypertensive rats: optimizing blockade of the renin-angiotensin system.
Topics: Alanine; Amiodarone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Captopril; Cardiomegaly; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Enzyme Inhibitors; Hypertension; Hypertrophy; Male; Mesenteric Arteries; Neprilysin; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2003 |
[Hypertension therapy. Does AT-1 blocker help love life?].
Topics: Angiotensin Receptor Antagonists; Angiotensins; Antihypertensive Agents; Clinical Trials as Topic; Erectile Dysfunction; Humans; Hypertension; Male; Orgasm; Penile Erection; Sex; Tetrazoles; Time Factors; Valine; Valsartan | 2003 |
[High dose sartan plus diuretic. More power in hypertension and its sequelae].
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Combinations; Heart Rate; Hydrochlorothiazide; Hypertension; Receptor, Angiotensin, Type 1; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan | 2003 |
Enhanced angiotensin-mediated responses in the nucleus tractus solitarii of spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensins; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Interactions; Functional Laterality; Glutamic Acid; Heart Rate; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Solitary Nucleus; Species Specificity; Tetrazoles; Valine; Valsartan | 2003 |
Cardiology patient page. Angiotensin receptor blockers.
Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Diuretics; Dizziness; Drug Combinations; Drug Interactions; Heart Failure; Humans; Hypertension; Imidazoles; Irbesartan; Kidney Diseases; Losartan; Olmesartan Medoxomil; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan | 2003 |
[Fast-acting sartan. High blood pressure therapy without long waiting time].
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Olmesartan Medoxomil; Rats; Tetrazoles; Time Factors; Valine; Valsartan | 2003 |
Role of angiotensin II and reactive oxygen species in cyclosporine A-dependent hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antioxidants; Blood Pressure; Creatinine; Cyclic N-Oxides; Cyclosporine; Hypertension; Immunosuppressive Agents; Male; Proteinuria; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Spin Labels; Tetrazoles; Valine; Valsartan | 2003 |
[Double profit for hypertensive patients. Blood pressure decreases--frequency of coitus increases].
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Coitus; Erectile Dysfunction; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2003 |
[Dosage equivalents of AT1-receptor antagonists available in Germany].
Topics: Acrylates; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Germany; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Olmesartan Medoxomil; Placebos; Telmisartan; Tetrazoles; Therapeutic Equivalency; Thiophenes; Time Factors; Valine; Valsartan | 2003 |
Successful treatment of severe hypertension with the combination of angiotensin converting enzyme inhibitor and angiotensin II receptor blocker.
Topics: Adult; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Humans; Hypertension; Male; Severity of Illness Index; Tetrazoles; Thiazepines; Valine; Valsartan | 2003 |
[Episodes of depression with attempted suicide after taking valsartan with hydrochlorothiazide].
Topics: Adult; Antihypertensive Agents; Depression; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Suicide, Attempted; Tetrazoles; Valine; Valsartan | 2003 |
Combined treatment with an AT1 receptor blocker and angiotensin converting enzyme inhibitor has an additive effect on inhibiting neointima formation via improvement of nitric oxide production and suppression of oxidative stress.
Topics: Angioplasty, Balloon; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Carotid Artery Injuries; Disease Models, Animal; Hypertension; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Tetrazoles; Tunica Intima; Valine; Valsartan | 2004 |
[AT-1 blockers are different in their effects. The forgetful patients begin to notice it especially].
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diuretics; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Losartan; Meta-Analysis as Topic; Placebos; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors; Stroke; Tetrazoles; Time Factors; Valine; Valsartan | 2003 |
RhoA activation in vascular smooth muscle cells from stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Cells, Cultured; Cyclic AMP; Cyclic GMP; Hypertension; Muscle, Smooth, Vascular; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Signal Transduction; Stroke; Tetrazoles; Valine; Valsartan | 2004 |
Valsartan treatment of hypertension--does VALUE add value?
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Endpoint Determination; Humans; Hypertension; Losartan; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Valine; Valsartan | 2004 |
Blood pressure dependent and independent effects of antihypertensive treatment on clinical events in the VALUE Trial.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
Effects of the angiotensin-1 receptor blocker valsartan compared with amlodipine on renal hemodynamics.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Glomerular Filtration Rate; Humans; Hypertension; Microcirculation; Receptor, Angiotensin, Type 1; Renal Circulation; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
[The value of VALUE--a hypertension study which compared valsartan with amlodipine. New data support early, optimal blood pressure control for high-risk patients].
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Risk Factors; Tetrazoles; Valine; Valsartan | 2004 |
[First fixed combination of sartan and high-dosage diuretic. A strong duo against high blood pressure].
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Patient Compliance; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan | 2004 |
[Hyperkalemia. Main symptoms: muscle weakness, cardiac arrhythmias].
Topics: Arrhythmias, Cardiac; Drug Therapy, Combination; Electrocardiography; Heart Failure; Humans; Hyperkalemia; Hypertension; Male; Middle Aged; Muscle Weakness; Spironolactone; Tetrazoles; Valine; Valsartan | 2004 |
Systemic hemodynamics in non-anesthetized L-NAME- and DOCA-salt-treated mice.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiac Output; Desoxycorticosterone; Drug Synergism; Enzyme Inhibitors; Hemodynamics; Hypertension; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Sodium Chloride; Tetrazoles; Time Factors; Valine; Valsartan; Vascular Resistance | 2004 |
Effects of telmisartan 80 mg and valsartan 160 mg on ambulatory blood pressure in patients with essential hypertension.
Topics: Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Humans; Hypertension; Telmisartan; Tetrazoles; Valine; Valsartan | 2004 |
[New combination of high dosage sartan and 25 mg HCT. Systolic blood pressure lowered by 21 mmHg].
Topics: Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Receptor, Angiotensin, Type 1; Tetrazoles; Valine; Valsartan | 2004 |
Sartans for hypertension--implications of the Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Clinical Trials as Topic; Humans; Hypertension; Tetrazoles; Valine; Valsartan | 2004 |
Abrogation of oxidative stress improves insulin sensitivity in the Ren-2 rat model of tissue angiotensin II overexpression.
Topics: Administration, Oral; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cyclic N-Oxides; Disease Models, Animal; Glucose; Hypertension; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Spin Labels; Tetrazoles; Valine; Valsartan | 2005 |
[Despite drug treatment, ever second hypertensive patient with morning blood pressure too high].
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Circadian Rhythm; Clinical Trials as Topic; Drug Administration Schedule; Humans; Hypertension; Losartan; Telmisartan; Tetrazoles; Valine; Valsartan | 2004 |
[Preventing end-organ damage in hypertension. What is the significance of the VALUE Study for general practice?].
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Cardiovascular Diseases; Cause of Death; Humans; Hypertension; Myocardial Infarction; Randomized Controlled Trials as Topic; Survival Rate; Tetrazoles; Valine; Valsartan | 2004 |
VALUE in hypertension treatment.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Cardiovascular Diseases; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2004 |
[AT1 blocker or calcium antagonist in treatment of hypertension. What protects the heart better?].
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Cardiovascular Diseases; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Hypertension; Risk Factors; Tetrazoles; Valine; Valsartan | 2004 |
[VALUE study underscores the significance of reaching aimed blood pressure values for minimizing cardiovascular risks].
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors; Sodium Chloride Symporter Inhibitors; Tetrazoles; Time Factors; Valine; Valsartan | 2004 |
Angiotensin receptor blockers and myocardial infarction.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Myocardial Infarction; Tetrazoles; Truth Disclosure; Valine; Valsartan | 2004 |
Valuable lessons from VALUE.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Humans; Hypertension; Tetrazoles; Valine; Valsartan | 2004 |
The value of VALUE: the importance of lowering blood pressure quickly.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Middle Aged; Risk Factors; Tetrazoles; Valine; Valsartan | 2004 |
Telmisartan is a promising cardiometabolic sartan due to its unique PPAR-gamma-inducing property.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Cardiovascular Diseases; Diabetes Mellitus; Diabetes Mellitus, Type 2; Humans; Hypertension; Insulin Resistance; PPAR gamma; Renin-Angiotensin System; Telmisartan; Tetrazoles; Valine; Valsartan | 2005 |
Automated office and home phone-transmitted blood pressure recordings in uncontrolled hypertension treated with valsartan and hydrochlorothiazide.
Topics: Adult; Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Automation; Blood Pressure; Blood Pressure Determination; Blood Pressure Monitoring, Ambulatory; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Oscillometry; Telephone; Tetrazoles; Time Factors; Valine; Valsartan | 2004 |
Changes in plasma lipids during renin-angiotensin system blockade by combination therapy (enalapril plus valsartan) in patients with diabetes and hypertension.
Topics: Diabetes Mellitus, Type 2; Drug Therapy, Combination; Enalapril; Humans; Hypertension; Lipids; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2005 |
Is there more to life than blood pressure?
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
NAD(P)H-dependent superoxide production in platelets: the role of angiotensin II and protein kinase C.
Topics: Aged; Alkaloids; Angiotensin II; Angiotensin Receptor Antagonists; Benzophenanthridines; Blood Platelets; Female; Humans; Hypertension; Male; Membrane Glycoproteins; Middle Aged; NADH, NADPH Oxidoreductases; NADPH Oxidase 2; NADPH Oxidases; Phenanthridines; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate; Tetrazoles; Valine; Valsartan | 2005 |
[The effect and mechanism of felodipine and valsartan on a novel salt-sensitive hypertensive rat induced by sensory denervation].
Topics: Animals; Antihypertensive Agents; Blood Pressure; Felodipine; Hypertension; Male; Rats; Rats, Wistar; Sodium Chloride, Dietary; Tetrazoles; Valine; Valsartan | 2005 |
Efficacy and duration of action of the four selective angiotensin II subtype 1 receptor blockers, losartan, candesartan, valsartan and telmisartan, in patients with essential hypertension determined by home blood pressure measurements.
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure Monitoring, Ambulatory; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Telmisartan; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2005 |
Aliskiren, a human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats.
Topics: Albuminuria; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Animals, Genetically Modified; Blood Pressure; Cardiomegaly; Dose-Response Relationship, Drug; Echocardiography; Fumarates; Humans; Hypertension; Kidney; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles; Valine; Valsartan | 2005 |
Modulation of 24-h blood pressure profiles: a new target for treatment?
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Humans; Hypertension; Tetrazoles; Valine; Valsartan | 2005 |
[Effects of angiotensin II on extracellular signal-regulated protein kinases signaling pathway in cultured vascular smooth muscle cells from Wistar-Kyoto rats and spontaneously hypertensive rats].
Topics: Angiotensin II; Animals; Cells, Cultured; Dual Specificity Phosphatase 1; Extracellular Signal-Regulated MAP Kinases; Hypertension; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Tetrazoles; Valine; Valsartan | 2005 |
Effects of angiotensin II receptor blockade with valsartan on pro-inflammatory cytokines in patients with essential hypertension.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; C-Reactive Protein; Cytokines; Female; Humans; Hypertension; Interleukin-6; Male; Middle Aged; Serum Amyloid A Protein; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan | 2005 |
Evaluation of intrarenal hemodynamics by Doppler ultrasonography for renoprotective effect of angiotensin receptor blockade.
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Female; Hemodynamics; Humans; Hypertension; Kidney; Kidney Diseases; Losartan; Male; Middle Aged; Tetrazoles; Ultrasonography, Doppler; Valine; Valsartan | 2005 |
[Hypertension and diabetic nephropathy, a dangerous duo].
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diuretics; Drug Therapy, Combination; Enalapril; Glomerular Filtration Rate; Humans; Hypertension; Male; Metabolic Syndrome; Ramipril; Tetrazoles; Valine; Valsartan | 2005 |
Effects of glitazones on blood pressure and vascular structure in mesenteric resistance arteries and basilar artery from genetically hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Basilar Artery; Blood Pressure; Disease Models, Animal; Drug Therapy, Combination; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hypertrophy, Left Ventricular; Mesenteric Arteries; Pioglitazone; Rats; Rats, Inbred SHR; Rats, Wistar; Rosiglitazone; Simvastatin; Tetrazoles; Thiazolidinediones; Tunica Media; Valine; Valsartan | 2005 |
ADMA and oxidative stress may relate to the progression of renal disease: rationale and design of the VIVALDI study.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arginine; Benzimidazoles; Benzoates; Clinical Protocols; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dinoprost; Endothelium, Vascular; Humans; Hypertension; Middle Aged; Multicenter Studies as Topic; Oxidative Stress; Randomized Controlled Trials as Topic; Renal Insufficiency; Telmisartan; Tetrazoles; Valine; Valsartan | 2005 |
[Dilation of the brachial artery in response to sublingual nitroglycerin can predict the antihypertensive effects of valsartan: a study using novel high-frequency high-frame-rate ultrasound imaging].
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Brachial Artery; Female; Humans; Hypertension; Male; Middle Aged; Nitroglycerin; Predictive Value of Tests; Tetrazoles; Ultrasonography; Valine; Valsartan; Vasodilation; Vasodilator Agents | 2006 |
Blood pressure control with valsartan and hydrochlorothiazide in clinical practice: the MACHT Observational Study.
Topics: Aged; Blood Pressure; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2006 |
[Successful mega studies with heart patients. Valsartan possesses cardioprotective action].
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Captopril; Clinical Trials as Topic; Drug Therapy, Combination; Heart Failure; Humans; Hypertension; Long-Term Care; Myocardial Infarction; Secondary Prevention; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2006 |
[Biliary stenosis, hepatitis A and valsartan: multifactorial hepatotoxicity in a surgical patient].
Topics: Antihypertensive Agents; Chemical and Drug Induced Liver Injury; Cholestasis; Hepatitis A; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2006 |
[Scientific evidence--applied in routine general practice. Successful decrease in pressure and risk].
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Drug Therapy, Combination; Evidence-Based Medicine; Family Practice; Germany; Heart Failure; Humans; Hypertension; Myocardial Infarction; Product Surveillance, Postmarketing; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2006 |
Effect of valsartan, an angiotensin II receptor blocker, on markers of oxidation and glycation in Japanese type 2 diabetic subjects: blood pressure-independent effect of valsartan.
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Body Weight; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Glycosylation; Humans; Hypertension; Japan; Tetrazoles; Thiobarbituric Acid Reactive Substances; Valine; Valsartan | 2006 |
Valsartan reduces serum cystatin C and the renal vascular resistance in patients with essential hypertension.
Topics: Adult; Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Flow Velocity; Blood Pressure; Creatinine; Cystatin C; Cystatins; Female; Humans; Hypertension; Japan; Kidney; Kidney Function Tests; Male; Middle Aged; Prospective Studies; Pulsatile Flow; Renal Circulation; Tetrazoles; Treatment Outcome; Ultrasonography, Doppler; Valine; Valsartan; Vascular Resistance | 2006 |
The Valsartan Antihypertensive Long-Term Use Evaluation trial: a study in contrasts.
Topics: Angiotensin II Type 1 Receptor Blockers; Cardiovascular Diseases; Drug Administration Schedule; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2006 |
Hematuria in a patient with class IV lupus nephritis.
Topics: Antihypertensive Agents; Biopsy; Cyclophosphamide; El Salvador; Female; Follow-Up Studies; Glomerular Basement Membrane; Glomerular Mesangium; Glucocorticoids; Hematuria; Hispanic or Latino; Humans; Hydrochlorothiazide; Hydroxychloroquine; Hypertension; Immunosuppressive Agents; Kidney Glomerulus; Lisinopril; Lupus Nephritis; Middle Aged; Nifedipine; Prednisone; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2006 |
Rationale and design: the VALsartan In Diastolic Dysfunction (VALIDD) Trial: evolving the management of diastolic dysfunction in hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Comorbidity; Diastole; Double-Blind Method; Echocardiography, Doppler; Humans; Hypertension; Randomized Controlled Trials as Topic; Research Design; Tetrazoles; Valine; Valsartan; Ventricular Dysfunction | 2006 |
Angiotensin receptor blockers and myocardial infarction: the importance of dosage.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Hypertension; Myocardial Infarction; Research Design; Tetrazoles; Valine; Valsartan | 2006 |
[Lowering blood pressure substantially--and the diabetes risk as well?].
Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitors; Circadian Rhythm; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Germany; Humans; Hypertension; Sodium Chloride Symporter Inhibitors; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2006 |
[Dilemma of antihypertensive therapy: high blood pressure diminishes, potency sometimes, too].
Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Atenolol; Diuretics; Erectile Dysfunction; Humans; Hypertension; Male; Myocardial Infarction; Tetrazoles; Time Factors; Valine; Valsartan | 2006 |
Lack of pharmacokinetic interactions of aliskiren, a novel direct renin inhibitor for the treatment of hypertension, with the antihypertensives amlodipine, valsartan, hydrochlorothiazide (HCTZ) and ramipril in healthy volunteers.
Topics: Adolescent; Adult; Amides; Amlodipine; Antihypertensive Agents; Drug Interactions; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Ramipril; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2006 |
Angiotensin II/AT2 receptor-induced vasodilation in stroke-prone spontaneously hypertensive rats involves nitric oxide and cGMP-dependent protein kinase.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Cyclic GMP-Dependent Protein Kinases; Hypertension; Nitric Oxide; Rats; Receptors, Angiotensin; Stroke; Tetrazoles; Valine; Valsartan; Vasodilation | 2006 |
Effects of valsartan therapy on protein glycoxidation.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Arginine; Dinoprost; Female; Glycation End Products, Advanced; Glycosylation; Humans; Hypertension; Lysine; Male; Malondialdehyde; Middle Aged; Oxidation-Reduction; Proteins; Tetrazoles; Valine; Valsartan | 2006 |
Retinal dysfunction in diabetic ren-2 rats is ameliorated by treatment with valsartan but not atenolol.
Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Antihypertensive Agents; Atenolol; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Electroretinography; Female; Hypertension; Neuroglia; Photic Stimulation; Rats; Retina; Tetrazoles; Valine; Valsartan | 2007 |
Risk of diabetes in a real-world setting among patients initiating antihypertensive therapy with valsartan or amlodipine.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Databases, Factual; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Multivariate Analysis; Retrospective Studies; Risk Assessment; Risk Factors; Risk Reduction Behavior; Tetrazoles; Time Factors; Treatment Outcome; United States; Valine; Valsartan | 2007 |
Sodium, arterial stiffness, and cardiovascular mortality in hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Carotid Arteries; Compliance; Disease Models, Animal; Hypertension; Male; Rats; Rats, Inbred SHR; Sodium Chloride, Dietary; Tetrazoles; Time Factors; Valine; Valsartan | 2007 |
Valsartan versus lisinopril or extended-release metoprolol in preventing cardiovascular and renal events in patients with hypertension.
Topics: Antihypertensive Agents; Cardiovascular Diseases; Delayed-Action Preparations; Female; Humans; Hypertension; Insurance Claim Review; Kidney Diseases; Lisinopril; Male; Metoprolol; Middle Aged; Multivariate Analysis; Retrospective Studies; Risk Factors; Tetrazoles; Valine; Valsartan | 2007 |
[Fetal toxicity of angiotensin-II-receptor inhibitors. Case report].
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Female; Humans; Hypertension; Infant, Newborn; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Renal Insufficiency; Tetrazoles; Valine; Valsartan | 2007 |
VALIDD should not invalidate angiotensin-receptor blockers.
Topics: Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Myocardial Infarction; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2007 |
[Convincing results from the JIKEI Study].
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Controlled Clinical Trials as Topic; Coronary Disease; Heart Failure; Humans; Hypertension; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2006 |
[Blood pressure lowering and risk reduction under treatment with valsartan and its combination with hydrochlorothiazide (HCT)].
Topics: Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Prospective Studies; Risk Factors; Tetrazoles; Valine; Valsartan | 2006 |
Angiotensin II type 1 receptor blocker reduces monocyte adhesion to endothelial cells in spontaneously hypertensive rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta; Atherosclerosis; Blood Pressure; Cell Adhesion; Deoxyguanosine; Endothelial Cells; Hydralazine; Hypertension; Male; Monocytes; Rats; Rats, Inbred SHR; Tetrazoles; Tunica Intima; Tunica Media; Valine; Valsartan | 2007 |
New-onset diabetes, antihypertensive treatment, and outcome.
Topics: Antihypertensive Agents; Cardiovascular Diseases; Diabetes Complications; Drug Administration Schedule; Humans; Hypertension; Prognosis; Risk Assessment; Risk Factors; Tetrazoles; Valine; Valsartan | 2007 |
Antihypertensive therapies.
Topics: Amides; Antihypertensive Agents; Blood Pressure; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diuretics; Drug Design; Drug Industry; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Renin; Tetrazoles; Valine; Valsartan | 2007 |
Effect of beta-adrenergic and renin-angiotensin system blockade on myocyte apoptosis and oxidative stress in diabetic hypertensive rats.
Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Diabetes Complications; Diabetes Mellitus, Experimental; Hypertension; Male; Metoprolol; Myocytes, Cardiac; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Streptozocin; Tetrazoles; Valine; Valsartan | 2007 |
Dual inhibition of the renin system by aliskiren and valsartan.
Topics: Amides; Antihypertensive Agents; Drug Therapy, Combination; Fumarates; Humans; Hyperkalemia; Hypertension; Renin; Tetrazoles; Valine; Valsartan | 2007 |
Novel mechanism and role of angiotensin II induced vascular endothelial injury in hypertensive diastolic heart failure.
Topics: Acetophenones; Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Apoptosis; Biopterins; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Endothelium, Vascular; Heart Failure, Diastolic; Hydralazine; Hypertension; Male; MAP Kinase Kinase Kinase 5; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Nitric Oxide Synthase Type III; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Signal Transduction; Sodium Chloride, Dietary; Superoxides; Tetrazoles; Time Factors; Valine; Valsartan; Vasodilation | 2007 |
Effect of antecedent hypertension and follow-up blood pressure on outcomes after high-risk myocardial infarction.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Captopril; Cardiovascular Diseases; Female; Follow-Up Studies; Heart Failure; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Prognosis; Risk Factors; Stroke; Tetrazoles; Valine; Valsartan; Ventricular Dysfunction, Left | 2008 |
The JIKEI trial.
Topics: Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Japan; Randomized Controlled Trials as Topic; Stroke; Tetrazoles; Valine; Valsartan | 2007 |
[New effective dosage of valsartan. High dosage--effective against high blood pressure].
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Diabetic Nephropathies; Dose-Response Relationship, Drug; Heart Failure; Humans; Hypertension; Prognosis; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2007 |
[Risk oriented therapy of hypertension. Lowering blood pressure and risk].
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Diabetic Nephropathies; Humans; Hypertension; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Valine; Valsartan | 2007 |
Two amlodipine/ARB combinations for hypertension.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Drug Combinations; Humans; Hypertension; Imidazoles; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2007 |
Effects of combined AT1 receptor antagonist/NEP inhibitor on vascular remodeling and cardiac fibrosis in SHRSP.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Endomyocardial Fibrosis; Endothelium, Vascular; Hydralazine; Hypertension; Male; Mesenteric Arteries; Neprilysin; Rats; Rats, Inbred SHR; Rats, Wistar; Stroke; Tetrazoles; Tyrosine; Valine; Valsartan | 2008 |
Switch strategies in the management of hypertension: a cost minimisation analysis of angiotensin receptor blocker based regimen.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cost-Benefit Analysis; Drug Costs; Humans; Hypertension; Irbesartan; Losartan; Markov Chains; Tetrazoles; Valine; Valsartan | 2008 |
Higher persistence with valsartan compared with enalapril in daily practice.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Prescriptions; Enalapril; Female; Humans; Hypertension; Male; Medicine; Middle Aged; Multivariate Analysis; Netherlands; Registries; Sex Factors; Specialization; Tetrazoles; Valine; Valsartan | 2007 |
Angiotensin receptor blockers: dose does matter.
Topics: Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Long-term safety, tolerability and efficacy of aliskiren in combination with valsartan in patients with hypertension: a 6-month interim analysis.
Topics: Aged; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hyperkalemia; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System; Risk Factors; Tetrazoles; Time Factors; Valine; Valsartan | 2008 |
Inhibition of vascular angiotensin-converting enzyme by telmisartan via the peroxisome proliferator-activated receptor gamma agonistic property in rats.
Topics: Acetylcholine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Carotid Arteries; Disease Models, Animal; Hypertension; Male; NADPH Oxidases; Peptidyl-Dipeptidase A; PPAR gamma; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Telmisartan; Tetrazoles; Valine; Valsartan; Vasodilation; Vasodilator Agents | 2007 |
Decreased expression of angiotensin II type 1 and type 2 receptors in the brain after long-term administration of antihypertensive drugs in stroke-prone spontaneously hypertensive rat.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Brain Stem; Calcium Channel Blockers; Cerebral Cortex; Disease Models, Animal; Down-Regulation; Enalapril; Hypertension; Male; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Stroke; Tetrazoles; Time Factors; Valine; Valsartan | 2008 |
Improved glucose metabolism following blockade of angiotensin converting enzyme but not angiotensin AT1 receptors.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzazepines; Blood Glucose; Blood Pressure; Body Weight; Drug Tolerance; Glucose Intolerance; Hypertension; Insulin Resistance; Lipids; Rats; Rats, Inbred SHR; Tetrazoles; Valine; Valsartan | 1995 |
Antihypertensive therapy augments endothelium-dependent relaxations in coronary arteries of spontaneously hypertensive rats.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Arginine; Coronary Vessels; Endothelium, Vascular; Hypertension; Muscle, Smooth, Vascular; Nitric Oxide; Pyrimidines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Valine; Valsartan | 1994 |
Effects of prolonged blockade of the renin angiotensin system on striated muscle microcirculation of spontaneously hypertensive rats.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzazepines; Body Weight; Hemodynamics; Hypertension; Male; Microcirculation; Muscle, Skeletal; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Tetrazoles; Time Factors; Valine; Valsartan | 1996 |
Vascular hypertrophy and albumin permeability in a rat model combining hypertension and diabetes mellitus. Effects of calcium antagonism, angiotensin converting enzyme inhibition, and angiotensin II-AT1-receptor blockade.
Topics: Analysis of Variance; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Capillary Permeability; Cardiomegaly; Coloring Agents; Coronary Vessels; Diabetes Mellitus, Experimental; Dihydropyridines; Evans Blue; Hypertension; Hypertrophy; Kidney; Male; Mesenteric Arteries; Ramipril; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Serum Albumin; Tetrazoles; Valine; Valsartan | 1996 |
Valsartan for hypertension.
Topics: Adult; Antihypertensive Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hypertension; Tetrazoles; Valine; Valsartan | 1997 |
Pharmacological profile of valsartan, a non-peptide angiotensin II type 1 receptor antagonist. 1st communication: antihypertensive effects of valsartan in hypertensive models.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Dogs; Enalapril; Heart Rate; Hypertension; Hypertension, Renal; Male; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Tetrazoles; Valine; Valsartan | 1997 |
Pharmacological profile of valsartan, a non-peptide angiotensin II type 1 receptor antagonist. 2nd communication: valsartan prevents end-organ damage in spontaneously hypertensive stroke-prone rats during 1-year treatment.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Body Weight; Cardiomegaly; Cerebrovascular Disorders; Enalapril; Heart Rate; Hypertension; Male; Mesentery; Muscle Contraction; Organ Size; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Valine; Valsartan | 1997 |
Secreted protein acidic and rich in cysteine expression after subtotal nephrectomy and blockade of the renin-angiotensin system.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Autoradiography; Fluorescent Antibody Technique, Indirect; Gene Expression; Hypertension; In Situ Hybridization; Male; Microscopy, Fluorescence; Nephrectomy; Osteonectin; Postoperative Period; Ramipril; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Valine; Valsartan | 1997 |
[AT1 receptor antagonists in treatment of hypertension].
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Hypertension; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1997 |
[Differential therapy of hypertension becomes more specific. Interview by Dr. R.-G. Sommer].
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Hypertension; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1997 |
Effects of valsartan and hydrochlorothiazide alone and in combination on blood pressure and heart rate in conscious-telemetered spontaneously hypertensive rats (SHR).
Topics: Animals; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Heart Rate; Hydrochlorothiazide; Hypertension; Male; Rats; Rats, Inbred SHR; Telemetry; Tetrazoles; Valine; Valsartan | 1998 |
Synergistic effects of combined converting enzyme inhibition and angiotensin II antagonism on blood pressure in conscious telemetered spontaneously hypertensive rats.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Blood Pressure; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Heart Rate; Hypertension; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Telemetry; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1998 |
Protective effects of valsartan and benazeprilat in salt-loaded stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Cerebrovascular Disorders; Genetic Predisposition to Disease; Heart Rate; Hypertension; Infusion Pumps; Kidney; Myocardium; Proteinuria; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System; Sodium Chloride; Tetrazoles; Valine; Valsartan | 1998 |
The effect of renin-angiotensin system inhibitors on pro- and anti-inflammatory cytokine production.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cytokines; Humans; Hypertension; Interleukin-1; Interleukin-6; Lipopolysaccharides; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan | 1998 |
Efficacy of angiotensin II antagonists in hypertension.
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diuretics; Drug Interactions; Drug Therapy, Combination; Humans; Hypertension; Irbesartan; Losartan; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1999 |
Valsartan. Just a second-line antihypertensive drug.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Pregnancy; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1999 |
By the way, doctor... I am 87 and have been taking blood pressure medications for years. In the past, side effects were a problem, but for about the last year I've done very well taking valsartan (Diovan) and hydrochlorothiazide (Esidrex). Now My blood pr
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Humans; Hydrochlorothiazide; Hypertension; Systole; Tetrazoles; Valine; Valsartan | 2000 |
AT1-receptor blockers.
Topics: Angiotensin I; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Heart Failure; Humans; Hypertension; Irbesartan; Losartan; Meta-Analysis as Topic; Tetrazoles; Valine; Valsartan | 2000 |
Enalapril and valsartan improve cyclosporine A-induced vascular dysfunction in spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Cyclosporine; Dose-Response Relationship, Drug; Enalapril; Hypertension; Male; Mesenteric Arteries; Nitroprusside; Norepinephrine; Rats; Rats, Inbred SHR; Renal Artery; Systole; Tetrazoles; Valine; Valsartan; Vasoconstriction; Vasodilation | 2000 |
Basilar artery remodelling in the genetically hypertensive rat: effects of nitric oxide synthase inhibition and treatment with valsartan and enalapril.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Basilar Artery; Blood Pressure; Brain; Enalapril; Enzyme Inhibitors; Hypertension; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR; Stroke; Tetrazoles; Valine; Valsartan; Ventricular Function, Left | 2000 |
Comparison of enalapril and valsartan in cyclosporine A-induced hypertension and nephrotoxicity in spontaneously hypertensive rats on high-sodium diet.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Bradykinin; Bradykinin Receptor Antagonists; Cyclosporine; Dose-Response Relationship, Drug; Drinking; Eating; Electrolytes; Enalapril; Heart Rate; Hypertension; Hypertrophy, Left Ventricular; Kallikreins; Kidney; Kidney Diseases; Male; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Renin; Sodium, Dietary; Tetrazoles; Urination; Valine; Valsartan | 2000 |
Favourable effects on arterial wave reflection and pulse pressure amplification of adding angiotensin II receptor blockade in resistant hypertension.
Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aorta; Arteries; Blood Pressure; Brachial Artery; Drug Resistance; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Pulse; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Regional Blood Flow; Tetrazoles; Valine; Valsartan | 2000 |
[Contribution of the renin-angiotensin system to blood pressure variability in hyperthyroid rats].
Topics: Angiotensin I; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Cardiomegaly; Chronic Disease; Disease Models, Animal; Fever; Fourier Analysis; Heart Rate; Hypertension; Hyperthyroidism; Injections, Intraperitoneal; Male; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Signal Processing, Computer-Assisted; Tachycardia; Tetrazoles; Thyroid Hormones; Thyrotoxicosis; Thyroxine; Valine; Valsartan; Weight Loss | 2000 |
Efficacy and tolerability of angiotensin II type 1 receptor antagonists in dialysis patients using AN69 dialysis membranes.
Topics: Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Drug Tolerance; Female; Humans; Hypertension; Male; Membranes, Artificial; Middle Aged; Renal Dialysis; Renal Insufficiency; Tetrazoles; Valine; Valsartan | 2001 |
Endothelial dysfunction and xanthine oxidoreductase activity in rats with human renin and angiotensinogen genes.
Topics: Acetylcholine; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihypertensive Agents; Dinoprost; Disease Models, Animal; Endothelium, Vascular; F2-Isoprostanes; Humans; Hypertension; Ketone Oxidoreductases; Male; Nitrates; Nitrites; Nitroprusside; Norepinephrine; Rats; Rats, Sprague-Dawley; Renal Artery; Renin; Superoxide Dismutase; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents; Vasodilation | 2001 |
Endothelial dysfunction and salt-sensitive hypertension in spontaneously diabetic Goto-Kakizaki rats.
Topics: Acetylcholine; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Diabetes Mellitus, Type 1; Endothelium, Vascular; Heart Rate; Hypertension; In Vitro Techniques; Mesenteric Arteries; Neprilysin; Nitroprusside; Norepinephrine; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium, Dietary; Tetrazoles; Valine; Valsartan | 2001 |
Inhibition of platelet activation in stroke-prone spontaneously hypertensive rats: comparison of losartan, candesartan, and valsartan.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Platelets; Blood Pressure; Humans; Hypertension; Losartan; P-Selectin; Platelet Activation; Platelet Adhesiveness; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stroke; Tetrazoles; Thromboxane A2; Valine; Valsartan | 2001 |
Salt sensitivity in genetically hypertensive rats of the Lyon strain.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Drug Resistance; Hypertension; Kidney; Male; Perindopril; Rats; Sodium Chloride, Dietary; Tetrazoles; Valine; Valsartan | 2001 |
Angiotensin-II-receptor inhibitors in pregnancy.
Topics: Abnormalities, Drug-Induced; Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Female; Humans; Hypertension; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, First; Prenatal Care; Risk Assessment; Sensitivity and Specificity; Tetrazoles; Time Factors; Valine; Valsartan | 2001 |
[The taboo topic of sexual activity in hypertensive patients. Pioneer study from Pavia proves: potency is not impaired].
Topics: Adult; Antihypertensive Agents; Carbazoles; Carvedilol; Cross-Over Studies; Double-Blind Method; Erectile Dysfunction; Humans; Hypertension; Male; Middle Aged; Propanolamines; Randomized Controlled Trials as Topic; Risk Factors; Taboo; Tetrazoles; Valine; Valsartan | 2001 |
Fetal toxic effects and angiotensin-II-receptor antagonists.
Topics: Abnormalities, Drug-Induced; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Female; Humans; Hypertension; Losartan; Pregnancy; Pregnancy Complications, Cardiovascular; Tetrazoles; Valine; Valsartan | 2001 |
Effect of combination of valsartan with benazepril on blood pressure and left ventricular hypertrophy in SHR.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Drug Therapy, Combination; Hypertension; Hypertrophy, Left Ventricular; Male; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Valine; Valsartan | 2000 |
Effects of nitric oxide synthase inhibition and low-salt diet on blood pressure and mesenteric resistance artery remodelling in genetically hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Enzyme Inhibitors; Heart Ventricles; Hypertension; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Sodium Chloride, Dietary; Systole; Tetrazoles; Valine; Valsartan; Vascular Resistance | 2001 |
Effects of valsartan on mechanical properties of the carotid artery in spontaneously hypertensive rats under high-salt diet.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Body Weight; Carotid Arteries; Dose-Response Relationship, Drug; Fibronectins; Hypertension; Immunohistochemistry; Male; Protein Isoforms; Rats; Rats, Inbred SHR; Sodium Chloride, Dietary; Tetrazoles; Valine; Valsartan | 2001 |
Influence of Valsartan on myocardial apoptosis in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Apoptosis; Cardiomegaly; Hypertension; Myocardium; Rats; Rats, Inbred SHR; Rats, Wistar; Tetrazoles; Valine; Valsartan | 2002 |
Combination of non-hypotensive doses of valsartan and enalapril improves survival of spontaneously hypertensive rats with endothelial dysfunction.
Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Creatinine; Dose-Response Relationship, Drug; Drug Combinations; Enalapril; Endothelium, Vascular; Hypertension; Male; Rats; Rats, Inbred SHR; Survival Analysis; Tetrazoles; Valine; Valsartan | 2000 |
[Sartans for lowering blood pressure. Hypertensive patients need not fear potency].
Topics: Antihypertensive Agents; Clinical Trials as Topic; Erectile Dysfunction; Humans; Hypertension; Male; Tetrazoles; Valine; Valsartan | 2002 |
Valsartan therapy has additive anti-oxidative effect to that of fluvastatin therapy against low-density lipoprotein oxidation: studies in hypercholesterolemic and hypertensive patients.
Topics: Analysis of Variance; Antioxidants; Drug Synergism; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hypercholesterolemia; Hypertension; Indoles; Lipoproteins, LDL; Oxidation-Reduction; Tetrazoles; Valine; Valsartan | 2002 |