Page last updated: 2024-08-24

valsartan and Cardiac Toxicity

valsartan has been researched along with Cardiac Toxicity in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (14.29)24.3611
2020's12 (85.71)2.80

Authors

AuthorsStudies
Chen, L; Cheng, D; Fang, W; Liu, H; Tu, W; Wang, H; Wang, Q; Yu, Q; Zhu, N1
Akokay, P; Dindaş, F; Doğduş, M; Ekici, M; Erhan, F; Güngör, H; Yılmaz, MB1
Kim, BS; Kim, HJ; Lee, AH; Lim, YH; Park, IH; Shin, JH1
Akagi, S; Amioka, N; Hatipoglu, OF; Ito, H; Miyoshi, T; Nakamura, K; Saito, Y; Yonezawa, T; Yoshida, M1
Gok, M; Ozturk, C; Yalta, K; Yalta, T1
Lewicka, E; Sławiński, G1
Dogan, Z; Durmus, S; Ergun, DD; Gelisgen, R; Sahin, H; Senturk, GE; Senyigit, A; Uzun, H1
Ahmed Rifaai, R; Bayoumi, AMA; Mahmoud Refaie, MM; Shehata, S1
Chen, L; Cheng, D; Li, Z; Meng, L; Tu, W; Wang, H; Wang, Q; Yu, Q1
Dankowski, R; Nowicka, A; Sacharczuk, W; Szałek-Goralewska, A; Szyszka, A; Łojko-Dankowska, A1
Alanazi, AZ; Alanazi, WA; Alhazzani, K; Alhoshani, AR; Aljerian, K; Alotaibi, FN; Alotaibi, MR; Alswayyed, M; As Sobeai, HM1
Asselin, CY; Cheung, D; Czaykowski, P; Dingman, B; Edel, A; Goyal, V; Jassal, DS; Kim, E; Mittal, I; Mozolevska, V; Ravandi, A; Schwartz, A; Shaikh, B; Singal, PK; Thliveris, J1
Balmforth, C; Jhund, PS; Lefkowitz, M; McMurray, JJV; Packer, M; Rizkala, AR; Rouleau, JL; Shen, L; Shi, V; Simpson, J; Solomon, SD; Swedberg, K; Zile, MR1
Abdeltawab Mohammed, M; Aboud, HM; Mahmoud, MO; Sabry, D; Shafiq Awad, M1

Trials

1 trial(s) available for valsartan and Cardiac Toxicity

ArticleYear
Outcomes and Effect of Treatment According to Etiology in HFrEF: An Analysis of PARADIGM-HF.
    JACC. Heart failure, 2019, Volume: 7, Issue:6

    Topics: Aged; Aminobutyrates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Cardiomyopathy, Alcoholic; Cardiomyopathy, Dilated; Cardiotoxicity; Cardiovascular Diseases; Cause of Death; Dangerous Behavior; Diabetic Cardiomyopathies; Drug Combinations; Enalapril; Female; Heart Failure; Heart Valve Diseases; Hospitalization; Humans; Hypertension; Infections; Male; Middle Aged; Mortality; Myocardial Ischemia; Peripartum Period; Stroke Volume; Tetrazoles; Treatment Outcome; Valsartan; Virus Diseases

2019

Other Studies

13 other study(ies) available for valsartan and Cardiac Toxicity

ArticleYear
MSCs enhances the protective effects of valsartan on attenuating the doxorubicin-induced myocardial injury via AngII/NOX/ROS/MAPK signaling pathway.
    Aging, 2021, 09-29, Volume: 13, Issue:18

    Topics: Animals; Antibiotics, Antineoplastic; Cardiotoxicity; Cell Survival; Doxorubicin; Humans; MAP Kinase Signaling System; Mesenchymal Stem Cells; Myocytes, Cardiac; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Valsartan

2021
Angiotensin receptor-neprilysin inhibition by sacubitril/valsartan attenuates doxorubicin-induced cardiotoxicity in a pretreatment mice model by interfering with oxidative stress, inflammation, and Caspase 3 apoptotic pathway.
    Anatolian journal of cardiology, 2021, Volume: 25, Issue:11

    Topics: Aminobutyrates; Angiotensins; Animals; Biphenyl Compounds; Cardiotoxicity; Caspase 3; Doxorubicin; Inflammation; Mice; Neprilysin; Oxidative Stress; Receptors, Angiotensin; Valsartan

2021
Sacubitril/valsartan reduces endoplasmic reticulum stress in a rat model of doxorubicin-induced cardiotoxicity.
    Archives of toxicology, 2022, Volume: 96, Issue:4

    Topics: Aminobutyrates; Animals; Biphenyl Compounds; Cardiotoxicity; Doxorubicin; Drug Combinations; Endoplasmic Reticulum Stress; Heart Failure; Male; Rats; Rats, Sprague-Dawley; Valsartan; Water

2022
LCZ696 ameliorates doxorubicin-induced cardiomyocyte toxicity in rats.
    Scientific reports, 2022, 03-23, Volume: 12, Issue:1

    Topics: Aminobutyrates; Animals; Apoptosis; Biphenyl Compounds; Cardiotoxicity; Doxorubicin; Drug Combinations; Male; Myocytes, Cardiac; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Valsartan

2022
Sacubitril-valsartan: Hope or hype in the battle against cardiotoxicity due to cancer treatment?
    Kardiologia polska, 2022, Volume: 80, Issue:9

    Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Cardiotoxicity; Drug Combinations; Heart Failure; Humans; Neoplasms; Stroke Volume; Tetrazoles; Valsartan

2022
Sacubitril-valsartan: Hope or hype in the battle against cardiotoxicity due to cancer treatment? Authors' reply.
    Kardiologia polska, 2022, Volume: 80, Issue:9

    Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Biphenyl Compounds; Cardiotoxicity; Drug Combinations; Heart Failure; Humans; Neoplasms; Stroke Volume; Tetrazoles; Valsartan

2022
Empagliflozin and sacubitril/valsartan reverse methotrexate cardiotoxicity by repressing oxidative stress and hypoxia in heart embryonic H9c2 cardiomyocytes - the role of morphology of mitochondria observed on electron microscopy.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:9

    Topics: Animals; Antioxidants; Cardiotoxicity; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Methotrexate; Microscopy, Electron; Mitochondria; Myocytes, Cardiac; Oxidants; Oxidative Stress; Rats; Valsartan

2023
Sacubitril/valsartan cardioprotective effect against cisplatin-induced cardiotoxicity via modulation of VEGF/eNOS and TLR4/TNFα/IL6 signalling pathways.
    The Journal of pharmacy and pharmacology, 2023, Sep-01, Volume: 75, Issue:9

    Topics: Animals; Cardiotoxicity; Cisplatin; Interleukin-6; Male; Nitric Oxide Synthase; Rats; Rats, Wistar; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha; Valsartan; Vascular Endothelial Growth Factor A

2023
Protective effects of valsartan administration on doxorubicin‑induced myocardial injury in rats and the role of oxidative stress and NOX2/NOX4 signaling.
    Molecular medicine reports, 2020, Volume: 22, Issue:5

    Topics: Animals; Apoptosis; Cardiotoxicity; Cell Line; Disease Models, Animal; Doxorubicin; Gene Expression Regulation; Heart Function Tests; Male; NADPH Oxidase 2; NADPH Oxidase 4; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Valsartan

2020
Sacubitril/valsartan as first-line therapy in anthracycline-induced cardiotoxicity.
    Kardiologia polska, 2021, Volume: 79, Issue:9

    Topics: Aminobutyrates; Anthracyclines; Biphenyl Compounds; Cardiotoxicity; Drug Combinations; Humans; Valsartan

2021
Protective effect of valsartan against doxorubicin-induced cardiotoxicity: Histopathology and metabolomics in vivo study.
    Journal of biochemical and molecular toxicology, 2021, Volume: 35, Issue:9

    Topics: Animals; Cardiotonic Agents; Cardiotoxicity; Doxorubicin; Gene Expression Regulation; Male; Metabolomics; Rats; Rats, Sprague-Dawley; Valsartan

2021
Role of renin-angiotensin system antagonists in the prevention of bevacizumab- and sunitinib-mediated cardiac dysfunction.
    American journal of physiology. Heart and circulatory physiology, 2019, 03-01, Volume: 316, Issue:3

    Topics: Amides; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Antineoplastic Agents; Bevacizumab; Cardiotoxicity; Fumarates; Hydralazine; Male; Mice; Mice, Inbred C57BL; Perindopril; Renin-Angiotensin System; Sunitinib; Valsartan; Ventricular Dysfunction

2019
Preparation and appraisal of self-assembled valsartan-loaded amalgamated Pluronic F127/Tween 80 polymeric micelles: Boosted cardioprotection
    Journal of drug targeting, 2020, Volume: 28, Issue:3

    Topics: Animals; Cardiotonic Agents; Cardiotoxicity; Cisplatin; Drug Liberation; Male; Micelles; NF-E2-Related Factor 2; Particle Size; Poloxamer; Polymers; Polysorbates; Rats; Rats, Wistar; RNA, Long Noncoding; Thioredoxins; Valsartan

2020