Page last updated: 2024-08-24

valsartan and Atherosclerosis

valsartan has been researched along with Atherosclerosis in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (52.38)29.6817
2010's10 (47.62)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Černe, D; Drevenšek, G; Janić, M; Lunder, M; Marc, J; Šabovič, M; Zupan, J1
Chai, M; Dong, Z; Ji, Q; Lin, Y; Liu, Y; Lu, Q; Meng, K; Wu, B; Yu, K; Zeng, Q; Zhang, J; Zhou, Y1
Fan, F; Li, S; Nie, W; Yan, H; Zhu, J; Zhu, W1
Higashi, Y; Hikita, K; Honda, M; Kawamoto, B; Muraoka, K; Saito, M; Sejima, T; Shimizu, S; Shimizu, T; Takenaka, A1
Chen, X; Deng, Y; Ding, D; Hu, X; Liao, Y; Pan, Y; Qiu, Z; Song, X; Wang, M; Wang, S; Wu, H; Yang, S; Zhang, H; Zhou, Y; Zhou, Z1
Alkhoder, A; Binongo, JN; Dhawan, SS; Jones, DP; Oshinski, JN; Quyyumi, AA; Ramadan, R1
He, S; Shi, W; Wang, L; Wang, X; Zhao, Y1
Akasaka, T; Goto, M; Ikejima, H; Imanishi, T; Kitabata, H; Kuroi, A; Mochizuki, S; Muragaki, Y; Takarada, S; Tanimoto, T; Tsujioka, H; Yoshida, K1
Akasaka, T; Goto, M; Ikejima, H; Imanishi, T; Kobayashi, K; Kuroi, A; Mochizuki, S; Muragaki, Y; Shiomi, M; Tsujioka, A; Tsujioka, H; Yoshida, K1
Baker, AB; Beigel, R; Chatzizisis, YS; Coskun, AU; Daley, W; Edelman, ER; Feldman, CL; Gerrity, RG; Jonas, M; Maynard, C; Stone, BV; Stone, PH1
Hawkins, NM; Huang, Z; Kober, L; Maggioni, AP; McMurray, JJ; Pfeffer, MA; Pieper, KS; Solomon, SD; Swedberg, K; Velazquez, EJ1
Horiuchi, M; Inaba, S; Iwai, M; Kanno, H; Mogi, M; Senba, I; Tomono, Y1
Fu, L; Gao, Q; Li, Y; Ma, D1
Janić, M; Jug, B; Lunder, M; Sabovič, M1
Aono, J; Higaki, J; Horiuchi, M; Inoue, K; Iwai, M; Nagai, T; Nishimura, K; Ogimoto, A; Okayama, H; Suzuki, J1
Chen, R; Horiuchi, M; Ide, A; Iwai, M; Li, Z; Min, LJ; Mogi, M; Okumura, M; Shiuchi, T; Suzuki, J; Tsuda, M1
Higaki, J; Horiuchi, M; Iwai, M; Mogi, M; Oshita, A; Suzuki, J; Yoshii, T1
Califf, R; Howlett, J; Køber, L; Maggioni, A; McMurray, J; Pfeffer, M; Pieper, K; Reed, S; Rouleau, J; Solomon, S; Swedberg, K; Van de Werf, F; Velazquez, E; White, H1
de Gasparo, M1
Azuma, K; Hirose, T; Ikeda, F; Kawamori, R; Mita, T; Ogihara, T; Otsuka, A; Tanaka, Y; Toyofuku, Y; Watada, H1
Horiuchi, M; Inaba, S; Iwai, M; Mogi, M; Tomono, Y1

Reviews

1 review(s) available for valsartan and Atherosclerosis

ArticleYear
New basic science initiatives with the angiotensin II receptor blocker valsartan.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2000, Volume: 1, Issue:2 Suppl

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atherosclerosis; Cell Proliferation; Endothelium, Vascular; Humans; Inflammation; Tetrazoles; Valine; Valsartan; Vasoconstriction; Ventricular Remodeling

2000

Trials

2 trial(s) available for valsartan and Atherosclerosis

ArticleYear
Chronic obstructive pulmonary disease is an independent predictor of death but not atherosclerotic events in patients with myocardial infarction: analysis of the Valsartan in Acute Myocardial Infarction Trial (VALIANT).
    European journal of heart failure, 2009, Volume: 11, Issue:3

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Atherosclerosis; Cause of Death; Confidence Intervals; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Prognosis; Proportional Hazards Models; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Survival Rate; Tetrazoles; Time Factors; Valine; Valsartan

2009
The effects of low-dose fluvastatin and valsartan combination on arterial function: a randomized clinical trial.
    European journal of internal medicine, 2012, Volume: 23, Issue:3

    Topics: Adult; Aging; Angiotensin II Type 1 Receptor Blockers; Atherosclerosis; Blood Flow Velocity; Brachial Artery; Carotid Arteries; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endothelium, Vascular; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Middle Aged; Pulsatile Flow; Tetrazoles; Valine; Valsartan; Vascular Stiffness

2012

Other Studies

18 other study(ies) available for valsartan and Atherosclerosis

ArticleYear
The low-dose atorvastatin and valsartan combination effectively protects the arterial wall from atherogenic diet-induced impairment in the guinea pig.
    European journal of pharmacology, 2014, Nov-15, Volume: 743

    Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Atherosclerosis; Atorvastatin; Diet, Atherogenic; Drug Therapy, Combination; Female; Guinea Pigs; Heptanoic Acids; Interleukin-1beta; Male; Nitric Oxide Synthase Type III; Plaque, Atherosclerotic; Protective Agents; Pyrroles; Tetrazoles; Valine; Valsartan

2014
Valsartan Attenuates Atherosclerosis via Upregulating the Th2 Immune Response in Prolonged Angiotensin II-Treated ApoE(-/-) Mice.
    Molecular medicine (Cambridge, Mass.), 2015, Feb-09, Volume: 21

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antibodies, Monoclonal; Apolipoproteins E; Atherosclerosis; Blood Pressure; Body Weight; Disease Models, Animal; Inflammation; Interleukin-5; Lipids; Male; Mice; Mice, Knockout; Plaque, Atherosclerotic; T-Lymphocyte Subsets; Th2 Cells; Valsartan

2015
Angiotensin II Promotes Atherogenesis through upregulating the Expression of Connexin 43 in Dendritic Cells.
    Cellular and molecular biology (Noisy-le-Grand, France), 2015, Jul-31, Volume: 61, Issue:3

    Topics: Angiotensin II; Animals; Apolipoproteins E; Atherosclerosis; Blood Pressure; CD40 Antigens; Cells, Cultured; Connexin 43; Dendritic Cells; Immunohistochemistry; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; Up-Regulation; Valsartan

2015
Vesicovascular reflexes in the spontaneously hypertensive rat.
    Life sciences, 2016, Jan-01, Volume: 144

    Topics: Animals; Antihypertensive Agents; Atherosclerosis; Blood Pressure; Blood Vessels; Epinephrine; Hypertension; Male; Myocardium; Nifedipine; Norepinephrine; Pulse Wave Analysis; Rats; Rats, Inbred SHR; Rats, Wistar; Reflex; Valsartan; Vasodilator Agents

2016
ATRQβ-001 vaccine prevents atherosclerosis in apolipoprotein E-null mice.
    Journal of hypertension, 2016, Volume: 34, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antibodies, Neutralizing; Aorta; Apolipoproteins E; Apoptosis; Atherosclerosis; Chemokine CCL2; Coronary Vessels; Endothelial Cells; Humans; Macrophages; Male; Mice; Mice, Knockout; Plaque, Atherosclerotic; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Scavenger Receptors, Class E; Vaccines; Valsartan; Vasoconstrictor Agents

2016
Effect of Angiotensin II Type I Receptor Blockade with Valsartan on Carotid Artery Atherosclerosis: A Double Blind Randomized Clinical Trial Comparing Valsartan and Placebo (EFFERVESCENT).
    American heart journal, 2016, Volume: 174

    Topics: Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Atherosclerosis; Carotid Artery Diseases; Carotid Intima-Media Thickness; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Prospective Studies; Treatment Outcome; Valsartan; Young Adult

2016
Nitric oxide synthesis-promoting effects of valsartan in human umbilical vein endothelial cells via the Akt/adenosine monophosphate-activated protein kinase/endothelial nitric oxide synthase pathway.
    Bosnian journal of basic medical sciences, 2017, May-20, Volume: 17, Issue:2

    Topics: Adenosine Monophosphate; AMP-Activated Protein Kinases; Antihypertensive Agents; Atherosclerosis; Chromones; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Human Umbilical Vein Endothelial Cells; Humans; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Valsartan

2017
Renin inhibitor aliskiren improves impaired nitric oxide bioavailability and protects against atherosclerotic changes.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 52, Issue:3

    Topics: Acetylcholine; Amides; Animals; Antihypertensive Agents; Atherosclerosis; Biopterins; Blood Pressure; Drug Therapy, Combination; Endothelium, Vascular; Fumarates; Heart Rate; HSP90 Heat-Shock Proteins; Hyperlipidemias; Inflammation Mediators; Lipids; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rabbits; Renin; Tetrazoles; Tyrosine; Valine; Valsartan; Vasodilation; Vasodilator Agents

2008
Combined effects of an 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor and angiotensin II receptor antagonist on nitric oxide bioavailability and atherosclerotic change in myocardial infarction-prone Watanabe heritable hyperlipidemic rabbits.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:6

    Topics: Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Animals; Atherosclerosis; Biological Availability; Drug Therapy, Combination; Echocardiography; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Myocardial Infarction; Nitric Oxide; Quinolines; Rabbits; Reactive Oxygen Species; Tetrazoles; Tyrosine; Valine; Valsartan

2008
Attenuation of inflammation and expansive remodeling by Valsartan alone or in combination with Simvastatin in high-risk coronary atherosclerotic plaques.
    Atherosclerosis, 2009, Volume: 203, Issue:2

    Topics: Animals; Antihypertensive Agents; Atherosclerosis; Blood Pressure; Coronary Artery Disease; Disease Models, Animal; Endothelium, Vascular; Inflammation; Lipids; Male; Rabbits; Risk; Simvastatin; Stress, Mechanical; Tetrazoles; Valine; Valsartan

2009
AT2 receptor deficiency attenuates adipocyte differentiation and decreases adipocyte number in atherosclerotic mice.
    American journal of hypertension, 2009, Volume: 22, Issue:7

    Topics: Adipocytes; Adipose Tissue; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Apolipoproteins E; Atherosclerosis; Cell Count; Cell Differentiation; Cholesterol, Dietary; Insulin Receptor Substrate Proteins; Male; Mice; Mice, Knockout; NADPH Oxidases; Receptor, Angiotensin, Type 2; Tetrazoles; Valine; Valsartan

2009
Valsartan alleviates atherosclerotic lesions in pulmonary arteries of rabbits via an endothelium-dependent mechanism.
    Acta cardiologica, 2010, Volume: 65, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Atherosclerosis; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Endothelium, Vascular; Lipids; Male; Nitric Oxide; Pulmonary Artery; Rabbits; Tetrazoles; Treatment Outcome; Valine; Valsartan; Vasodilation

2010
Deletion of the angiotensin II type 1a receptor prevents atherosclerotic plaque rupture in apolipoprotein E-/- mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:6

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apolipoproteins E; Atherosclerosis; Carotid Artery Diseases; Carotid Artery, Common; CD36 Antigens; Disease Models, Animal; Disease Progression; Focal Adhesion Kinase 1; Gene Deletion; JNK Mitogen-Activated Protein Kinases; Lipids; Lipoproteins, LDL; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Plaque, Atherosclerotic; Receptor, Angiotensin, Type 1; Rupture, Spontaneous; Superoxides; Tetrazoles; Time Factors; Valine; Valsartan

2012
Deletion of angiotensin II type 2 receptor exaggerated atherosclerosis in apolipoprotein E-null mice.
    Circulation, 2005, Sep-13, Volume: 112, Issue:11

    Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cells, Cultured; Gene Deletion; Imidazoles; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Oxidative Stress; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Tetrazoles; Valine; Valsartan

2005
Eplerenone with valsartan effectively reduces atherosclerotic lesion by attenuation of oxidative stress and inflammation.
    Arteriosclerosis, thrombosis, and vascular biology, 2006, Volume: 26, Issue:4

    Topics: Aldosterone; Animals; Aorta; Atherosclerosis; Blood Pressure; Cells, Cultured; Chemokine CCL2; Cholesterol, Dietary; Diet, Atherogenic; Enzyme Activation; Eplerenone; Inflammation; Male; Mice; Muscle, Smooth, Vascular; NADPH Oxidases; Oxidative Stress; Spironolactone; Superoxides; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan

2006
The effect of valsartan, captopril, or both on atherosclerotic events after acute myocardial infarction: an analysis of the Valsartan in Acute Myocardial Infarction Trial (VALIANT).
    Journal of the American College of Cardiology, 2006, Feb-21, Volume: 47, Issue:4

    Topics: Aged; Angina Pectoris; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Atherosclerosis; Captopril; Cardiovascular Diseases; Disease-Free Survival; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Randomized Controlled Trials as Topic; Recurrence; Stroke; Tetrazoles; Valine; Valsartan

2006
Angiotensin II type 1 receptor blocker reduces monocyte adhesion to endothelial cells in spontaneously hypertensive rats.
    Endocrine journal, 2007, Volume: 54, Issue:4

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta; Atherosclerosis; Blood Pressure; Cell Adhesion; Deoxyguanosine; Endothelial Cells; Hydralazine; Hypertension; Male; Monocytes; Rats; Rats, Inbred SHR; Tetrazoles; Tunica Intima; Tunica Media; Valine; Valsartan

2007
Blockade of AT1 receptor improves adipocyte differentiation in atherosclerotic and diabetic models.
    American journal of hypertension, 2008, Volume: 21, Issue:2

    Topics: Adipocytes, White; Adiponectin; Angiotensin II Type 1 Receptor Blockers; Animals; Apolipoproteins E; Atherosclerosis; Cell Differentiation; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Gene Deletion; Gene Expression; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Obesity; PPAR gamma; Receptor, Angiotensin, Type 1; Tetrazoles; Valine; Valsartan

2008