Page last updated: 2024-10-26

valproic acid and Vitamin B 12 Deficiency

valproic acid has been researched along with Vitamin B 12 Deficiency in 3 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Vitamin B 12 Deficiency: A nutritional condition produced by a deficiency of VITAMIN B 12 in the diet, characterized by megaloblastic anemia. Since vitamin B 12 is not present in plants, humans have obtained their supply from animal products, from multivitamin supplements in the form of pills, and as additives to food preparations. A wide variety of neuropsychiatric abnormalities is also seen in vitamin B 12 deficiency and appears to be due to an undefined defect involving myelin synthesis. (From Cecil Textbook of Medicine, 19th ed, p848)

Research Excerpts

ExcerptRelevanceReference
"Hyperhomocysteinemia is found to be closely associated with an enhanced risk of cerebral venous thrombosis."1.51An uncommon presentation of hyperhomocysteinemia and vitamin B ( D'Cruz, S; Kapur, V; Kaur, R, 2019)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Güneş, H1
Acıpayam, C1
Akgüngör, F1
Kütükçü, M1
Kapur, V1
D'Cruz, S1
Kaur, R1
Schwaninger, M1
Ringleb, P1
Winter, R1
Kohl, B1
Fiehn, W1
Rieser, PA1
Walter-Sack, I1

Other Studies

3 other studies available for valproic acid and Vitamin B 12 Deficiency

ArticleYear
Leukemia-like megaloblastic anemia in an autistic child receiving risperidone and valproic acid.
    Pediatrics international : official journal of the Japan Pediatric Society, 2020, Volume: 62, Issue:10

    Topics: Anemia, Megaloblastic; Autistic Disorder; Child; Humans; Leukemia; Risperidone; Valproic Acid; Vitam

2020
An uncommon presentation of hyperhomocysteinemia and vitamin B
    Journal of medical case reports, 2019, Feb-18, Volume: 13, Issue:1

    Topics: Adult; Anticoagulants; Anticonvulsants; Brain; Diuretics, Osmotic; Glycerol; Heparin; Humans; Hyperh

2019
Elevated plasma concentrations of homocysteine in antiepileptic drug treatment.
    Epilepsia, 1999, Volume: 40, Issue:3

    Topics: Age Factors; Ambulatory Care; Anticonvulsants; Carbamazepine; Convulsants; Depression, Chemical; Epi

1999