valproic acid has been researched along with Vasospasm, Intracranial in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Vasospasm, Intracranial: Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, CH | 1 |
| Tsai, YC | 1 |
| Tsai, TH | 1 |
| Kuo, KL | 1 |
| Su, YF | 1 |
| Chang, CH | 1 |
| Lin, CL | 1 |
| Tso, MK | 1 |
| Lass, E | 1 |
| Ai, J | 1 |
| Loch Macdonald, R | 1 |
2 other studies available for valproic acid and Vasospasm, Intracranial
| Article | Year |
|---|---|
Valproic Acid Reduces Vasospasm through Modulation of Akt Phosphorylation and Attenuates Neuronal Apoptosis in Subarachnoid Hemorrhage Rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Gene Expression Regulation; Humans; Neuro | 2021 |
Valproic Acid treatment after experimental subarachnoid hemorrhage.
Topics: Animals; Anticonvulsants; Cerebrovascular Circulation; Disease Models, Animal; Male; Mice, Inbred C5 | 2015 |