valproic acid has been researched along with Thrombocytopathy in 8 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Valproic acid (VPA) is an antiepileptic drug frequently used in children." | 1.34 | Severe bleeding complications during antiepileptic treatment with valproic acid in children. ( Albisetti, M; Cannizzaro, E; Schmugge, M; Wohlrab, G, 2007) |
| " These side-effects are dose-related, and the daily dosage should never exceed 40 mg/kg." | 1.26 | [Sodium valproate, platelet dysfunction and bleeding (author's transl)]. ( Loiseau, P, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cannizzaro, E | 1 |
| Albisetti, M | 1 |
| Wohlrab, G | 1 |
| Schmugge, M | 1 |
| Loiseau, P | 2 |
| Erenberg, G | 1 |
| Rothner, AD | 1 |
| Henry, CE | 1 |
| Cruse, RP | 1 |
| Torelli, D | 1 |
| Galeone, D | 1 |
| Lamontanara, G | 1 |
| von Voss, H | 2 |
| Schulte-Berbühl, R | 1 |
| Göbel, U | 2 |
| Klose, PK | 1 |
| Pache, HD | 1 |
| Uhl, HC | 1 |
| Petrich, C | 1 |
| Karch, D | 1 |
| Schulz, HU | 1 |
1 review available for valproic acid and Thrombocytopathy
| Article | Year |
|---|---|
Sodium valproate, platelet dysfunction, and bleeding.
Topics: Blood Platelet Disorders; Hemorrhagic Disorders; Humans; Platelet Function Tests; Valproic Acid | 1981 |
1 trial available for valproic acid and Thrombocytopathy
| Article | Year |
|---|---|
Valproic acid in the treatment of intractable absence seizures in children: a single-blind clinical and quantitative EEG study.
Topics: Adolescent; Anticonvulsants; Blood Platelet Disorders; Child; Child, Preschool; Clinical Trials as T | 1982 |
6 other studies available for valproic acid and Thrombocytopathy
| Article | Year |
|---|---|
Severe bleeding complications during antiepileptic treatment with valproic acid in children.
Topics: Adolescent; Anticonvulsants; Blood Platelet Disorders; Child, Preschool; Epilepsy; Humans; Infant; I | 2007 |
[Sodium valproate, platelet dysfunction and bleeding (author's transl)].
Topics: Blood Platelet Disorders; Epilepsy; Humans; Thrombocytopenia; Valproic Acid | 1981 |
Several hematic parameters in children treated with sodium valproate.
Topics: Blood Platelet Disorders; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Female; H | 1982 |
Side effects of sodium valproate (sodium di-N-propylacetate) on malonyldialdehyde-production and other platelet function tests.
Topics: Adult; Blood Platelet Disorders; Blood Platelets; Child; Epilepsy; Factor IX; Factor VIII; Fibrinoge | 1978 |
[Disorders of hemostasis caused by dipropylacetate].
Topics: Blood Platelet Disorders; Child; Disseminated Intravascular Coagulation; Epilepsy, Tonic-Clonic; Fem | 1977 |
Letter: Sodium valproate and platelet function.
Topics: Anticonvulsants; Blood Coagulation Tests; Blood Platelet Disorders; Child; Humans; Thrombelastograph | 1976 |