valproic acid has been researched along with Thoracic Neoplasms in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Thoracic Neoplasms: New abnormal growth of tissue in the THORAX.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Valproic acid (VPA) is an established drug in the long-term therapy of epilepsy." | 1.36 | Epigenetic modifiers as anticancer drugs: effectiveness of valproic acid in neural crest-derived tumor cells. ( Ferreri, AM; Guerra, F; Orlandi, M; Papi, A; Rocchi, P, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Papi, A | 1 |
| Ferreri, AM | 1 |
| Rocchi, P | 1 |
| Guerra, F | 1 |
| Orlandi, M | 1 |
| Ziauddin, MF | 1 |
| Yeow, WS | 1 |
| Maxhimer, JB | 1 |
| Baras, A | 1 |
| Chua, A | 1 |
| Reddy, RM | 1 |
| Tsai, W | 1 |
| Cole, GW | 1 |
| Schrump, DS | 1 |
| Nguyen, DM | 1 |
2 other studies available for valproic acid and Thoracic Neoplasms
| Article | Year |
|---|---|
Epigenetic modifiers as anticancer drugs: effectiveness of valproic acid in neural crest-derived tumor cells.
Topics: Anticonvulsants; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation | 2010 |
Valproic acid, an antiepileptic drug with histone deacetylase inhibitory activity, potentiates the cytotoxic effect of Apo2L/TRAIL on cultured thoracic cancer cells through mitochondria-dependent caspase activation.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Non-Small-Cell Lung; Caspases; Cell Line, Tumor | 2006 |