valproic acid has been researched along with Syncope in 11 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Syncope: A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This open label study suggests that the combination of valproate, lamotrigine, and a benzodiazepine can markedly reduce the frequency of epileptic drop attacks in patients with generalized or multifocal epilepsies." | 9.15 | Long-term control of epileptic drop attacks with the combination of valproate, lamotrigine, and a benzodiazepine: a 'proof of concept,' open label study. ( Bastos, FA; Machado, VH; Palmini, A; Rotert, R, 2011) |
| "This open label study suggests that the combination of valproate, lamotrigine, and a benzodiazepine can markedly reduce the frequency of epileptic drop attacks in patients with generalized or multifocal epilepsies." | 5.15 | Long-term control of epileptic drop attacks with the combination of valproate, lamotrigine, and a benzodiazepine: a 'proof of concept,' open label study. ( Bastos, FA; Machado, VH; Palmini, A; Rotert, R, 2011) |
| " The absence seizures were suppressed by treatment with valproate sodium, which had no effect on the self-induced apneas." | 3.67 | Syncopal attacks compulsively self-induced by Valsalva's maneuver associated with typical absence seizures. A case report. ( Aicardi, J; Gastaut, H; Misès, J, 1988) |
| "To evaluate Epileptic drop attacks (EDAs) treatment options among pediatric neurologists in Saudi Arabia (SA) and to develop a recommendation scheme for the management of EDAs in SA." | 1.91 | Treatment of drop attacks: Anti-seizure drug choices of pediatric neurologists in Saudi Arabia. ( Abbar, A; Abdulsbhan, M; Alelyani, R; Alhiniah, M; Alrajhi, A; Alshahrani, A; Badawi, A; Jan, M; Muthaffar, O; Rajab, R, 2023) |
| "Epileptic myoclonus is generally treated by valproate monotherapy, and this therapy has confirmed efficacy." | 1.38 | Stepwise synchronization through the corpus callosum is one cause of myoclonic jerks. ( Arai, H; Iimura, Y; Nakajima, M; Sugano, H, 2012) |
| "He had a subsequent syncopal episode and despite accidental destruction of his patient activator, vital ECG data from the event were transmitted wirelessly, enabling a cardiac arrhythmia to be excluded." | 1.36 | All is not lost: utilizing continuous remote ILR monitoring to diagnose syncope. ( Hong, PS; Sulke, N; Veasey, RA, 2010) |
| "We diagnosed this case as Lissauer's general paresis and treated with intravenous benzylpenicillin potassium 24 million units per day for 2 weeks." | 1.36 | [A case of Lissauer form of paretic neurosyphilis with drop attacks and dementia]. ( Arahata, S; Araki, E; Fujii, N; Furuya, H; Syouzaki, T, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Alhiniah, M | 1 |
| Alshahrani, A | 1 |
| Rajab, R | 1 |
| Alelyani, R | 1 |
| Badawi, A | 1 |
| Abbar, A | 1 |
| Abdulsbhan, M | 1 |
| Alrajhi, A | 1 |
| Muthaffar, O | 1 |
| Jan, M | 1 |
| Mishra, D | 1 |
| Juneja, M | 1 |
| Hong, PS | 1 |
| Veasey, RA | 1 |
| Sulke, N | 1 |
| Syouzaki, T | 1 |
| Arahata, S | 1 |
| Araki, E | 1 |
| Furuya, H | 1 |
| Fujii, N | 1 |
| Machado, VH | 1 |
| Palmini, A | 1 |
| Bastos, FA | 1 |
| Rotert, R | 1 |
| Iimura, Y | 1 |
| Sugano, H | 1 |
| Nakajima, M | 1 |
| Arai, H | 1 |
| Teng, PR | 1 |
| Shen, TY | 1 |
| Lai, TJ | 1 |
| Narang, M | 1 |
| Dua, T | 1 |
| Gomber, S | 1 |
| Mahajan, V | 1 |
| Gelisse, P | 1 |
| Serafini, A | 1 |
| Davy, JM | 1 |
| Balbe, M | 1 |
| Coubes, P | 1 |
| Crespel, A | 1 |
| van Rijckevorsel, K | 1 |
| Saussu, F | 1 |
| de Barsy, T | 1 |
| Aicardi, J | 1 |
| Gastaut, H | 1 |
| Misès, J | 1 |
1 trial available for valproic acid and Syncope
| Article | Year |
|---|---|
Long-term control of epileptic drop attacks with the combination of valproate, lamotrigine, and a benzodiazepine: a 'proof of concept,' open label study.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Drug Therapy, Combinat | 2011 |
10 other studies available for valproic acid and Syncope
| Article | Year |
|---|---|
Treatment of drop attacks: Anti-seizure drug choices of pediatric neurologists in Saudi Arabia.
Topics: Anticonvulsants; Child; Cross-Sectional Studies; Humans; Levetiracetam; Male; Neurologists; Saudi Ar | 2023 |
Ventricular ectopic beats in a child receiving carbamazepine.
Topics: Anticonvulsants; Carbamazepine; Child; Electrocardiography; Epilepsy; Humans; Male; Syncope; Valproi | 2013 |
All is not lost: utilizing continuous remote ILR monitoring to diagnose syncope.
Topics: Anxiety; Arrhythmias, Cardiac; Electrocardiography, Ambulatory; Epilepsy, Absence; Humans; Male; Mid | 2010 |
[A case of Lissauer form of paretic neurosyphilis with drop attacks and dementia].
Topics: Dementia; Humans; Male; Middle Aged; Neurosyphilis; Syncope; Valproic Acid | 2010 |
Stepwise synchronization through the corpus callosum is one cause of myoclonic jerks.
Topics: Anticonvulsants; Cognition Disorders; Corpus Callosum; Cortical Synchronization; Drug Resistance; El | 2012 |
Sulpiride-associated torsade de pointes in a woman with bipolar disorder.
Topics: Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Drug Therapy, Combination; Electrocardiogr | 2012 |
Cardiac syncope from occult transposition masquerading as convulsive epilepsy.
Topics: Anticonvulsants; Child, Preschool; Diagnosis, Differential; Heart Block; Humans; Male; Seizures; Syn | 2005 |
Video-EEG in syncopal attack due to ocular compression in an adolescent mistreated for epilepsy.
Topics: Adolescent; Cerebral Cortex; Diagnosis, Differential; Diagnostic Errors; Electroencephalography; Epi | 2007 |
Bradycardia, an epileptic ictal manifestation.
Topics: Adult; Anticonvulsants; Bradycardia; Electrocardiography; Electroencephalography; Epilepsy; Epilepsy | 1995 |
Syncopal attacks compulsively self-induced by Valsalva's maneuver associated with typical absence seizures. A case report.
Topics: Apnea; Child; Child Behavior; Compulsive Behavior; Electroencephalography; Epilepsy, Absence; Female | 1988 |