Page last updated: 2024-10-26

valproic acid and Stunted Growth

valproic acid has been researched along with Stunted Growth in 7 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

ExcerptRelevanceReference
"We have evaluated 19 children who were exposed to valproic acid (VPA) in utero to look for manifestations of a fetal valproate syndrome (FVS), as proposed by Di Liberti et al."4.77Verification of the fetal valproate syndrome phenotype. ( Ardinger, HH; Atkin, JF; Blackston, RD; Clarren, SK; Elsas, LJ; Flannery, DB; Harrod, MJ; Lammer, EJ; Livingstone, S; Pellock, JM, 1988)
" Anthropometric measurements, staging of pubertal maturation, and clinical manifestations of hyperandrogenism were assessed, as well as measurement of serum levels of testosterone, dehydroepiandrosterone sulfate (DHEAS), sex hormone-binding globulin (SHBG), and free androgen index (FAI)."3.72Physical growth and endocrinal disorders during pubertal maturation in girls with epilepsy. ( Abd El-Basset, FZ; El Barbary, NS; El-Khayat, HA; Hakky, SM; Mohamed, MS; Nassef, NM; Tohamy, SM; Tomoum, HY; Zaky, AA, 2004)
"Corneal dermoids may regress spontaneously."1.72Spontaneous Partial Regression of Bilateral Grade III Corneal Dermoids Associated With Fetal Valproate Spectrum Disorder. ( Colak, D; Kiratli, H; Koç, İ, 2022)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Kiratli, H1
Colak, D1
Koç, İ1
El-Khayat, HA1
Abd El-Basset, FZ1
Tomoum, HY1
Tohamy, SM1
Zaky, AA1
Mohamed, MS1
Hakky, SM1
El Barbary, NS1
Nassef, NM1
Penning, C1
van der Wouden, JC1
Kurowski, HL1
Gospe, SM1
Zeman, FJ1
Grivetti, LE1
Van Maele-Fabry, G1
Clotman, F1
Gofflot, F1
Bosschaert, J1
Picard, JJ1
Massa, G1
Lecoutere, D1
Casaer, P1
Ardinger, HH1
Atkin, JF1
Blackston, RD1
Elsas, LJ1
Clarren, SK1
Livingstone, S1
Flannery, DB1
Pellock, JM1
Harrod, MJ1
Lammer, EJ1

Reviews

1 review available for valproic acid and Stunted Growth

ArticleYear
Verification of the fetal valproate syndrome phenotype.
    American journal of medical genetics, 1988, Volume: 29, Issue:1

    Topics: Abnormalities, Drug-Induced; Facial Bones; Female; Growth Disorders; Humans; Infant; Infant, Newborn

1988

Other Studies

6 other studies available for valproic acid and Stunted Growth

ArticleYear
Spontaneous Partial Regression of Bilateral Grade III Corneal Dermoids Associated With Fetal Valproate Spectrum Disorder.
    Cornea, 2022, Sep-01, Volume: 41, Issue:9

    Topics: Abnormalities, Drug-Induced; Child; Choristoma; Corneal Diseases; Dermoid Cyst; Female; Growth Disor

2022
Physical growth and endocrinal disorders during pubertal maturation in girls with epilepsy.
    Epilepsia, 2004, Volume: 45, Issue:9

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Dehydroepiandrosterone; Epilepsy; Female; Growth;

2004
Increased plasma leptin levels and valproate use in patients with Rett syndrome.
    The Journal of pediatrics, 2007, Volume: 151, Issue:4

    Topics: Anticonvulsants; Biomarkers; Growth Disorders; Humans; Leptin; Rett Syndrome; Valproic Acid

2007
Nutritional factors and anticonvulsant therapies: effect on growth in children with epilepsy.
    The American journal of clinical nutrition, 1993, Volume: 58, Issue:6

    Topics: Carbamazepine; Child; Child Nutritional Physiological Phenomena; Child, Preschool; Cross-Sectional S

1993
Postimplantation mouse embryos cultured in vitro. Assessment with whole-mount immunostaining and in situ hybridization.
    The International journal of developmental biology, 1997, Volume: 41, Issue:2

    Topics: Animals; Congenital Abnormalities; Culture Techniques; Embryo, Mammalian; Embryonic and Fetal Develo

1997
Prognosis in fetal valproate syndrome.
    The Journal of pediatrics, 1987, Volume: 111, Issue:2

    Topics: Behavior; Child, Preschool; Female; Growth Disorders; Humans; Pregnancy; Prenatal Exposure Delayed E

1987