valproic acid has been researched along with Shock, Septic in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Z | 1 |
| Li, Y | 1 |
| Chong, W | 1 |
| Deperalta, DK | 1 |
| Duan, X | 1 |
| Liu, B | 1 |
| Halaweish, I | 1 |
| Zhou, P | 1 |
| Alam, HB | 1 |
| Shang, Y | 1 |
| Jiang, YX | 1 |
| Ding, ZJ | 1 |
| Shen, AL | 1 |
| Xu, SP | 1 |
| Yuan, SY | 1 |
| Yao, SL | 1 |
2 other studies available for valproic acid and Shock, Septic
| Article | Year |
|---|---|
Creating a prosurvival phenotype through a histone deacetylase inhibitor in a lethal two-hit model.
Topics: Acute Lung Injury; Animals; Ascitic Fluid; Histone Deacetylase Inhibitors; Interleukin-6; Male; Pero | 2014 |
Valproic acid attenuates the multiple-organ dysfunction in a rat model of septic shock.
Topics: Acute Kidney Injury; Animals; Blotting, Western; Chemical and Drug Induced Liver Injury; Lung Injury | 2010 |