valproic acid has been researched along with Sensation Disorders in 7 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Sensation Disorders: Disorders of the special senses (i.e., VISION; HEARING; TASTE; and SMELL) or somatosensory system (i.e., afferent components of the PERIPHERAL NERVOUS SYSTEM).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propranolol was titrated to 180 mg/d in 28 patients, to 240 mg/d in 1, and downward in 3." | 2.68 | A comparison of divalproex with propranolol and placebo for the prophylaxis of migraine without aura. ( Kaniecki, RG, 1997) |
| "We included 43 patients with migraine without aura in a triple-blind, placebo- and dose-controlled, crossover study of the prophylactic effect of slow-release sodium valproate; 34 patients completed the trial." | 2.67 | Sodium valproate has a prophylactic effect in migraine without aura: a triple-blind, placebo-controlled crossover study. ( Brinck, T; Jensen, R; Olesen, J, 1994) |
| "A novel intrastriatal rotenone model of Parkinson's disease was used to examine the neuroprotective effects of valproic acid (VPA), which is known to upregulate neurotrophic factors and other protective proteins in the brain." | 1.40 | Neuroprotection by valproic acid in an intrastriatal rotenone model of Parkinson's disease. ( Carriere, CH; Kang, NH; Niles, LP, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carriere, CH | 1 |
| Kang, NH | 1 |
| Niles, LP | 1 |
| Yao, ZG | 1 |
| Jing, HY | 1 |
| Wang, DM | 1 |
| Lv, BB | 1 |
| Li, JM | 1 |
| Liu, FF | 1 |
| Fan, H | 1 |
| Sun, XC | 1 |
| Qin, YJ | 1 |
| Zhao, MQ | 1 |
| Salazar, Z | 1 |
| Tschopp, L | 1 |
| Calandra, C | 1 |
| Micheli, F | 1 |
| Williams, JA | 1 |
| Barreiro, CJ | 1 |
| Nwakanma, LU | 1 |
| Lange, MS | 1 |
| Kratz, LE | 1 |
| Blue, ME | 1 |
| Berrong, J | 1 |
| Patel, ND | 1 |
| Gott, VL | 1 |
| Troncoso, JC | 1 |
| Johnston, MV | 1 |
| Baumgartner, WA | 1 |
| Jensen, R | 1 |
| Brinck, T | 1 |
| Olesen, J | 1 |
| Rothrock, JF | 1 |
| Kaniecki, RG | 1 |
2 trials available for valproic acid and Sensation Disorders
| Article | Year |
|---|---|
Sodium valproate has a prophylactic effect in migraine without aura: a triple-blind, placebo-controlled crossover study.
Topics: Adult; Female; Headache; Humans; Male; Middle Aged; Migraine Disorders; Muscle Contraction; Placebos | 1994 |
A comparison of divalproex with propranolol and placebo for the prophylaxis of migraine without aura.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Cross-Over Studies; Female; GABA Agents; Human | 1997 |
5 other studies available for valproic acid and Sensation Disorders
| Article | Year |
|---|---|
Neuroprotection by valproic acid in an intrastriatal rotenone model of Parkinson's disease.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Dopaminergic Neurons; Functional Laterality; | 2014 |
Valproic acid ameliorates olfactory dysfunction in APP/PS1 transgenic mice of Alzheimer's disease: Ameliorations from the olfactory epithelium to the olfactory bulb.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Mice; Olfactory Bulb; Olfactory Mucosa; | 2016 |
Pisa syndrome and parkinsonism secondary to valproic acid in Huntington's disease.
Topics: Aged; Anticonvulsants; Humans; Huntington Disease; Male; Parkinson Disease, Secondary; Sensation Dis | 2008 |
Valproic acid prevents brain injury in a canine model of hypothermic circulatory arrest: a promising new approach to neuroprotection during cardiac surgery.
Topics: Animals; Apoptosis; Aspartic Acid; Behavior, Animal; Biomarkers; Brain; Brain Chemistry; Brain Damag | 2006 |
Successful treatment of persistent migraine aura with divalproex sodium.
Topics: Female; Humans; Middle Aged; Migraine Disorders; Sensation Disorders; Valproic Acid | 1997 |