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valproic acid and Seizures, Febrile

valproic acid has been researched along with Seizures, Febrile in 62 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Seizures, Febrile: Seizures that occur during a febrile episode. It is a common condition, affecting 2-5% of children aged 3 months to five years. An autosomal dominant pattern of inheritance has been identified in some families. The majority are simple febrile seizures (generally defined as generalized onset, single seizures with a duration of less than 30 minutes). Complex febrile seizures are characterized by focal onset, duration greater than 30 minutes, and/or more than one seizure in a 24 hour period. The likelihood of developing epilepsy (i.e., a nonfebrile seizure disorder) following simple febrile seizures is low. Complex febrile seizures are associated with a moderately increased incidence of epilepsy. (From Menkes, Textbook of Child Neurology, 5th ed, p784)

Research Excerpts

ExcerptRelevanceReference
" The administration of two antiepileptic drugs, Sodium Valproate and Clonazepam, reduces significantly seizures occurrence compared with unmedicated controls."5.05[DPA and clonazepam activity in febrile convulsions: preliminary results]. ( Florio, C; Sorge, F; Steardo, L; Steardo, R, 1980)
" Intermittent diazepam prophylaxis at times of fever may or may not reduce the recurrence rate significantly, but there is no data to suggest that it improves the long-term outcome, as compared with short-term seizure control, in terms of IQ, cognition, academic progress, motor control, and subsequent epilepsy."4.81[Febrile convulsions, Treatment and prognosis]. ( Knudsen, FU, 2001)
"100 children with the first episode of febrile seizures (from 6 months to 4 years old) were investigated."2.71[Mexidol in treatment of children with generalized epilepsy and febrile seizures]. ( Kapanadze, N; Natriashvili, G; Natriashvili, S, 2005)
"The number of complex recurrences, however, were significantly higher in the valproic acid group than in the diazepam group."2.67Intermittent prophylaxis in febrile convulsions: diazepam or valproic acid? ( Ankerhus, J; Brems, M; Daugbjerg, P; Knudsen, FU; Mai, J, 1990)
"Valproic acid and diazepam were found to be equally effective in reducing the risk of recurrence of febrile convulsions."2.66Prophylactic treatment with valproic acid or diazepam in children with febrile convulsions. ( Hvorslev, V; Lee, K; Taudorf, K, 1986)
"Rate of recurrent febrile seizures was 16% in control group, and 5."2.66[Preventing the recurrence of febrile seizures: intermittent prevention with rectal diazepam compared with continuous treatment with sodium valproate]. ( Cabrero, A; Fernández, RM; Fidalgo, I; Mosquera, C; Rodríguez, J, 1987)
" They were subsequently followed up as outpatients, and Phenobarbital and sodium valproate levels were measured regularly to ascertain compliance with the treatment and to adjust the dosage accordingly."2.65Prevention of recurrent febrile convulsions--a randomized therapeutic assay: sodium valproate, phenobarbital and placebo. ( Gilly, R; Mamelle, JC; Mamelle, N; Plasse, JC; Revol, M, 1984)
" The dosage was phenobarbitone 3-6 mg/kg per day; sodium valproate 30-60 mg/kg per day."2.65Continuous sodium valproate or phenobarbitone in the prevention of 'simple' febrile convulsions. Comparison by a double-blind trial. ( Bower, B; Ngwane, E, 1980)
"Febrile seizures are the most common seizure disorder in childhood, occurring in 2-5% of children."2.41Treatment of children with simple febrile seizures: the AAP practice parameter. American Academy of Pediatrics. ( Baumann, RJ; Duffner, PK, 2000)
"Status epilepticus is an emergency situation that can often lead to death or neurocognitive deficits despite adequate therapy is conducted."2.41[Status epilepticus and its treatment]. ( Futó, J; Katalin, T, 2002)
"The risk of recurrences was significantly lower in children receiving continuous phenobarbital therapy than placebo (odds ratio 0."2.40A meta-analytic review of the preventive treatment of recurrences of febrile seizures. ( Rantala, H; Tarkka, R; Uhari, M, 1997)
"Five days later, febrile convulsions were induced by hyperthermal bath (45 Celcius degree)."1.36[Prophylactic efficacy of levetiracetam, valproate or phenobarbital on febrile convulsions in rats]. ( Cheng, M; Huang, Z; Li, SX, 2010)
"The role of prolonged febrile seizures in the genesis of hippocampal sclerosis is controversial; statistical analysis and data from epilepsy surgery suggest a causal relationship."1.35Development of hippocampal sclerosis after a complex febrile seizure. ( Bernhard, MK; Merkenschlager, A; Pfluger, T; Todt, H, 2009)
"Juvenile myoclonic epilepsy developed in two patients, and cryptogenic partial epilepsy in another."1.33Benign myoclonic epilepsy in infants: electroclinical features and long-term follow-up of 34 patients. ( Auvin, S; Badinand, N; De Bellecize, J; Isnard, H; Lamblin, MD; Motte, J; Pandit, F; Vallée, L; Villeneuve, N, 2006)
"The families of 42 children with febrile seizures were recruited after pediatric or neuropediatric consultation."1.31Treatment of febrile seizures: the influence of treatment efficacy and side-effect profile on value to parents. ( Camfield, CS; Camfield, PR; Dooley, JM; Gordon, KE; MacSween, J, 2001)
"Guidelines for the management of febrile seizures are presented."1.29[Treatment of febrile convulsions in infants]. ( Bourrillon, A, 1995)
"The low risk of non-febrile seizures and important side-effects of antiepileptic drugs have limited the use of continuous prophylaxis in children with recurrent febrile seizures."1.29[Risk factors in recurrent febrile seizures]. ( Fernández-Barreiro, A; Martín-Fernández, JJ; Moltó-Jordà, JM; Prieto-Muñoz, I; Salmerón, P; Villaverde, R, 1996)
"A pharmacokinetic study of sodium valproate (DPA) was undertaken in children treated with this drug after a febrile convulsion."1.27[Pharmacokinetic elements of sodium valproate. Use in febrile convulsions in children]. ( Beaune, P; Lenoir, G; Novella-Pequinot, MA; Perignon, F, 1983)
"Only when the epilepsy is uncontrolled despite high plasma concentrations which cannot be raised because of side effects, a second drug should be given."1.27[Pharmacotherapy of epilepsy--current problems and controversies]. ( Schmidt, D, 1983)
" Children can begin to receive valproate treatment in a dosage of 20 to 30 mg/kg per day in two or three divided doses."1.27Valproate monotherapy in children. ( Murphy, JV, 1988)
" Thus in adequate dosage both phenobarbitone and valproic acid were significantly better than no treatment in preventing febrile convulsions (p less than 0."1.26Successful prophylaxis against febrile convulsions with valproic acid or phenobarbitone. ( Smith, JA; Wallace, SJ, 1980)
"Phenobarbital has been shown to offer effective prophylaxis against childhood febrile convulsions."1.26Sodium valproate versus phenobarbital in the prophylactic treatment of febrile convulsions in childhood. ( Lee, K; Melchior, JC, 1981)
" The remaining 95 children were given sodium valproate; the dosage was 20-25 mg/kg/day b."1.26Phenobarbital, primidone and sodium valproate in the prophylaxis of febrile convulsions. ( Minagawa, K; Miura, H, 1981)
"A Consensus Development Conference on Febrile Seizures was held at the National Institutes of Health in USA in May 1980."1.26["Fever convulsions" in children. Current viewpoints on diagnosis, therapy and prognosis]. ( Helwig, H; Staudt, F, 1982)

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-199044 (70.97)18.7374
1990's6 (9.68)18.2507
2000's9 (14.52)29.6817
2010's2 (3.23)24.3611
2020's1 (1.61)2.80

Authors

AuthorsStudies
Yang, Y1
Zeng, Q1
Cheng, M2
Niu, X1
Xiangwei, W1
Gong, P1
Li, W1
Ma, J1
Zhang, X1
Yang, X1
Yang, Z1
Sun, D1
Zhou, S1
Liao, J1
Jiang, Y1
Zhang, Y1
Merkenschlager, A1
Todt, H1
Pfluger, T1
Bernhard, MK1
Huang, Z1
Li, SX1
Kaur, M1
Marawar, R1
Ritaccio, A1
Natriashvili, G1
Natriashvili, S1
Kapanadze, N1
Auvin, S1
Pandit, F1
De Bellecize, J1
Badinand, N1
Isnard, H1
Motte, J1
Villeneuve, N1
Lamblin, MD1
Vallée, L1
Nowack, WJ2
Johnson, RN2
Hanna, GR2
Steardo, L1
Florio, C1
Sorge, F1
Steardo, R1
Perignon, F1
Novella-Pequinot, MA1
Beaune, P1
Lenoir, G1
Johnson, DD1
Crawford, KD1
Crawford, RD1
Williams, LH1
Reynolds, RP1
Emery, JL1
de la Morena García, E1
Borges Domingo, MT1
Escorihuela, R1
Sandiumenge, J1
Schmidt, D1
Herranz, JL2
Armijo, JA2
Arteaga, R1
Olson, JE1
Scher, MS1
Holtzman, D1
Monaco, F1
Mele, G2
Meloni, T2
Franca, V2
Sotgia, A1
Mutani, R1
Mamelle, N2
Mamelle, JC2
Plasse, JC2
Revol, M2
Gilly, R2
Ogunmekan, AO1
Gram, L2
Bentsen, KD2
Wallace, SJ2
Smith, JA2
Jeavons, PM1
Ngwane, E1
Bower, B1
Cowen, J1
Harris, F1
Pearce, JL1
Giles, HM1
Addy, DP2
Lee, K2
Melchior, JC1
Minagawa, K1
Miura, H1
Valiente, R1
Masala, A1
Alagna, S1
Rovasio, PP1
Rassu, S1
Staudt, F1
Helwig, H1
Bourrillon, A1
Martín-Fernández, JJ1
Moltó-Jordà, JM1
Villaverde, R1
Salmerón, P1
Prieto-Muñoz, I1
Fernández-Barreiro, A1
Rantala, H1
Tarkka, R1
Uhari, M1
Cavazzuti, GB1
Baumann, RJ1
Duffner, PK1
Nagarajan, L1
Johnston, K1
Williams, S1
Knudsen, FU2
Gordon, KE1
Dooley, JM1
Camfield, PR1
Camfield, CS1
MacSween, J1
Autret-Leca, E1
Ployet, JL1
Jonville-Bera, AP1
Katalin, T1
Futó, J1
Julien, RM1
Fowler, GW1
Vigevano, F1
Di Capua, M1
Fusco, L1
Ricci, S1
Sebastianelli, R1
Lucchini, P1
Daugbjerg, P1
Brems, M1
Mai, J1
Ankerhus, J1
McKinlay, I1
Newton, R1
Klepel, H1
Koch, RD1
Tzenow, H1
Taudorf, K1
Hvorslev, V1
Ishikawa, T1
Ogino, C1
Furuyama, M1
Kanayama, M1
Awaya, A1
Yamaguchi, A1
Rosman, NP1
Mosquera, C1
Rodríguez, J1
Cabrero, A1
Fidalgo, I1
Fernández, RM1
Newton, RW1
Murphy, JV1
Rohmann, E1
Sengbusch, S1
Hobusch, D1
Popp, K1
Schwebke, D1
Koivikko, M1

Reviews

8 reviews available for valproic acid and Seizures, Febrile

ArticleYear
[Use of phenobarbital in febrile convulsive crisis].
    Anales espanoles de pediatria, 1983, Volume: 18, Issue:2

    Topics: Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Nervous System Diseases; Phenobarbital; Recurr

1983
A meta-analytic review of the preventive treatment of recurrences of febrile seizures.
    The Journal of pediatrics, 1997, Volume: 131, Issue:6

    Topics: Anticonvulsants; Chi-Square Distribution; Child; Diazepam; Drug Administration Schedule; Fever; Huma

1997
Treatment of children with simple febrile seizures: the AAP practice parameter. American Academy of Pediatrics.
    Pediatric neurology, 2000, Volume: 23, Issue:1

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Drug Therapy, Combin

2000
[Febrile convulsions, Treatment and prognosis].
    Ugeskrift for laeger, 2001, Feb-19, Volume: 163, Issue:8

    Topics: Analgesics, Non-Narcotic; Anticonvulsants; Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Phe

2001
[Status epilepticus and its treatment].
    Orvosi hetilap, 2002, Jun-02, Volume: 143, Issue:22

    Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Epilepsia Partialis Continua; Epilepsies, Par

2002
Phenobarbitone and febrile convulsions.
    Archives of disease in childhood, 1990, Volume: 65, Issue:9

    Topics: Humans; Infant; Intelligence; Phenobarbital; Seizures, Febrile; Time Factors; Valproic Acid

1990
Valproate: an updated review.
    Acta neurologica Scandinavica, 1985, Volume: 72, Issue:2

    Topics: Abnormalities, Drug-Induced; Brain Diseases; Chemical and Drug Induced Liver Injury; Coma; Dyskinesi

1985
Febrile seizures.
    Emergency medicine clinics of North America, 1987, Volume: 5, Issue:4

    Topics: Child; Child, Preschool; Diagnosis, Differential; Diazepam; Electroencephalography; Epilepsy; Female

1987

Trials

12 trials available for valproic acid and Seizures, Febrile

ArticleYear
[Mexidol in treatment of children with generalized epilepsy and febrile seizures].
    Georgian medical news, 2005, Issue:122

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalogra

2005
[DPA and clonazepam activity in febrile convulsions: preliminary results].
    Bollettino della Societa italiana di biologia sperimentale, 1980, Jun-15, Volume: 56, Issue:11

    Topics: Benzodiazepinones; Child, Preschool; Clinical Trials as Topic; Clonazepam; Humans; Infant; Receptors

1980
Prevention of recurrent febrile convulsions--a randomized therapeutic assay: sodium valproate, phenobarbital and placebo.
    Neuropediatrics, 1984, Volume: 15, Issue:1

    Topics: Child, Preschool; Clinical Trials as Topic; Dose-Response Relationship, Drug; Electroencephalography

1984
Controlled and comparative trials of valproate performed in Europe and Asia.
    Epilepsia, 1984, Volume: 25 Suppl 1

    Topics: Adolescent; Adult; Asia; Carbamazepine; Child; Clinical Trials as Topic; Epilepsy; Europe; Humans; P

1984
Continuous sodium valproate or phenobarbitone in the prevention of 'simple' febrile convulsions. Comparison by a double-blind trial.
    Archives of disease in childhood, 1980, Volume: 55, Issue:3

    Topics: Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Male; Phenobarbital; Random A

1980
[Efficacy of sodium dipropylacetate compared with phenobarbital and placebo in the prevention of recurrence of febrile convulsions].
    Pediatrie, 1982, Volume: 37, Issue:6

    Topics: Child, Preschool; Clinical Trials as Topic; Female; Humans; Infant; Male; Phenobarbital; Placebos; R

1982
Prevention of febrile convulsions with dipropylacetate (Depakine).
    Epilepsia, 1975, Volume: 16, Issue:4

    Topics: Anticonvulsants; Child, Preschool; Humans; Phenobarbital; Primidone; Seizures, Febrile; Valproic Aci

1975
Intermittent prophylaxis in febrile convulsions: diazepam or valproic acid?
    Acta neurologica Scandinavica, 1990, Volume: 82, Issue:1

    Topics: Diazepam; Female; Humans; Infant; Male; Prospective Studies; Randomized Controlled Trials as Topic;

1990
Intention to treat febrile convulsions with rectal diazepam, valproate or phenobarbitone.
    Developmental medicine and child neurology, 1989, Volume: 31, Issue:5

    Topics: Administration, Rectal; Child; Child, Preschool; Diazepam; Female; Humans; Infant; Male; Phenobarbit

1989
Prophylactic treatment with valproic acid or diazepam in children with febrile convulsions.
    Acta paediatrica Scandinavica, 1986, Volume: 75, Issue:4

    Topics: Child; Child, Preschool; Clinical Trials as Topic; Diazepam; Female; Humans; Infant; Male; Recurrenc

1986
[Preventing the recurrence of febrile seizures: intermittent prevention with rectal diazepam compared with continuous treatment with sodium valproate].
    Anales espanoles de pediatria, 1987, Volume: 27, Issue:5

    Topics: Administration, Rectal; Adolescent; Adult; Child; Diazepam; Drug Administration Schedule; Female; Hu

1987
Randomised controlled trials of phenobarbitone and valproate in febrile convulsions.
    Archives of disease in childhood, 1988, Volume: 63, Issue:10

    Topics: Child; Child, Preschool; Clinical Trials as Topic; Humans; Infant; Phenobarbital; Random Allocation;

1988

Other Studies

42 other studies available for valproic acid and Seizures, Febrile

ArticleYear
GABRB3-related epilepsy: novel variants, clinical features and therapeutic implications.
    Journal of neurology, 2022, Volume: 269, Issue:5

    Topics: Electroencephalography; Epilepsies, Myoclonic; Epilepsy; Fever; Humans; Infant; Levetiracetam; Recep

2022
Development of hippocampal sclerosis after a complex febrile seizure.
    European journal of pediatrics, 2009, Volume: 168, Issue:4

    Topics: Anticonvulsants; Child, Preschool; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Sclerosis;

2009
[Prophylactic efficacy of levetiracetam, valproate or phenobarbital on febrile convulsions in rats].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2010, Volume: 12, Issue:7

    Topics: Animals; Anticonvulsants; Levetiracetam; Male; Phenobarbital; Piracetam; Rats; Recurrence; Seizures,

2010
Postictal psychosis in a 3-year-old child.
    Journal of child neurology, 2012, Volume: 27, Issue:10

    Topics: Child, Preschool; Electroencephalography; Female; Humans; Psychotic Disorders; Seizures, Febrile; Va

2012
Benign myoclonic epilepsy in infants: electroclinical features and long-term follow-up of 34 patients.
    Epilepsia, 2006, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Cerebral Cortex; Child; Child, Preschool; Comorbid

2006
Effect of hyperthermia on a thalamocortical system in the kitten and the cat: a preliminary study.
    Neurological research, 1983, Volume: 5, Issue:3

    Topics: Animals; Cats; Cerebral Cortex; Fever; Phenytoin; Seizures, Febrile; Thalamus; Valproic Acid

1983
[Pharmacokinetic elements of sodium valproate. Use in febrile convulsions in children].
    Archives francaises de pediatrie, 1983, Volume: 40, Issue:1

    Topics: Child, Preschool; Humans; Infant; Kinetics; Seizures, Febrile; Valproic Acid

1983
Febrile seizures in epileptic chicks: the effects of phenobarbital, phenytoin and valproate.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1983, Volume: 10, Issue:2

    Topics: Animals; Chickens; Disease Models, Animal; Phenobarbital; Phenytoin; Reaction Time; Seizures, Febril

1983
Pancreatitis during sodium valproate treatment.
    Archives of disease in childhood, 1983, Volume: 58, Issue:7

    Topics: Acute Disease; Female; Hemorrhage; Humans; Infant; Pancreatitis; Seizures, Febrile; Valproic Acid

1983
[Plasma levels of valproic acid].
    Revista clinica espanola, 1983, Apr-30, Volume: 169, Issue:2

    Topics: Child, Preschool; Female; Humans; Immunoenzyme Techniques; Infant; Male; Seizures, Febrile; Valproic

1983
[Pharmacotherapy of epilepsy--current problems and controversies].
    Fortschritte der Neurologie-Psychiatrie, 1983, Volume: 51, Issue:11

    Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy,

1983
Effectiveness and toxicity of phenobarbital, primidone, and sodium valproate in the prevention of febrile convulsions, controlled by plasma levels.
    Epilepsia, 1984, Volume: 25, Issue:1

    Topics: Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Male; Phenobarbital; Prim

1984
Effects of anticonvulsants on hyperthermia-induced seizures in the rat pup.
    Epilepsia, 1984, Volume: 25, Issue:1

    Topics: Animals; Animals, Newborn; Behavior, Animal; Body Temperature; Differential Threshold; Disease Model

1984
A longitudinal study of valproate free fraction in the specific age group at greatest risk for febrile convulsions (children below 3 years).
    Epilepsia, 1984, Volume: 25, Issue:2

    Topics: Female; Humans; Infant; Kinetics; Male; Seizures, Febrile; Tears; Valproic Acid

1984
Prevention of febrile convulsions with sodium valproate.
    The Central African journal of medicine, 1984, Volume: 30, Issue:2

    Topics: Follow-Up Studies; Humans; Infant; Seizures, Febrile; Time Factors; Valproic Acid

1984
Successful prophylaxis against febrile convulsions with valproic acid or phenobarbitone.
    British medical journal, 1980, Feb-09, Volume: 280, Issue:6211

    Topics: Child, Preschool; Female; Humans; Infant; Male; Phenobarbital; Recurrence; Seizures; Seizures, Febri

1980
Prophylaxis against febrile convulsions.
    British medical journal, 1980, Mar-01, Volume: 280, Issue:6214

    Topics: Child; Humans; Phenobarbital; Seizures; Seizures, Febrile; Valproic Acid

1980
Prophylaxis against febrile convulsions.
    British medical journal, 1980, Mar-22, Volume: 280, Issue:6217

    Topics: Chemical and Drug Induced Liver Injury; Child; Humans; Seizures; Seizures, Febrile; Valproic Acid

1980
Prophylaxis against febrile convulsions.
    British medical journal, 1980, Apr-19, Volume: 280, Issue:6221

    Topics: Child, Preschool; Diagnosis, Differential; Epilepsy; Humans; Infant; Phenobarbital; Seizures; Seizur

1980
Prevention of simple febrile convulsions.
    Archives of disease in childhood, 1980, Volume: 55, Issue:10

    Topics: Child; Humans; Phenobarbital; Seizures; Seizures, Febrile; Valproic Acid

1980
Continuous sodium valproate or phenobarbitone in the prevention of 'simple' febrile convulsions.
    Archives of disease in childhood, 1980, Volume: 55, Issue:8

    Topics: Humans; Infant; Infant, Newborn; Phenobarbital; Recurrence; Seizures; Seizures, Febrile; Valproic Ac

1980
Prophylaxis and febrile convulsions.
    Archives of disease in childhood, 1981, Volume: 56, Issue:2

    Topics: Child; Child, Preschool; Diazepam; Epilepsy; Humans; Infant; Phenobarbital; Recurrence; Seizures; Se

1981
Febrile convulsions: long-term treatment.
    British medical journal (Clinical research ed.), 1981, Feb-28, Volume: 282, Issue:6265

    Topics: Anticonvulsants; Child; Child, Preschool; Humans; Infant; Phenobarbital; Prognosis; Recurrence; Seiz

1981
Sodium valproate versus phenobarbital in the prophylactic treatment of febrile convulsions in childhood.
    European journal of pediatrics, 1981, Volume: 137, Issue:2

    Topics: Child Behavior Disorders; Child, Preschool; Female; Humans; Infant; Male; Phenobarbital; Seizures, F

1981
Phenobarbital, primidone and sodium valproate in the prophylaxis of febrile convulsions.
    Brain & development, 1981, Volume: 3, Issue:4

    Topics: Child, Preschool; Dose-Response Relationship, Drug; Humans; Infant; Phenobarbital; Primidone; Recurr

1981
[Relation between plasma levels of valproic acid alone and its efficacy and toxicity in pediatric patients under chronic treatment].
    Archivos de farmacologia y toxicologia, 1981, Volume: 7, Issue:1

    Topics: Child; Child, Preschool; Drug Evaluation; Epilepsy; Humans; Infant; Seizures; Seizures, Febrile; Val

1981
Febrile convulsions: intellectual progress in relation to anticonvulsant therapy and to recurrence of fits.
    Archives of disease in childhood, 1982, Volume: 57, Issue:2

    Topics: Child Development; Child, Preschool; Humans; Infant; Intelligence; Intelligence Tests; Phenobarbital

1982
Effect of long-term treatment with sodium valproate on gonadotrophin and prolactin secretion in paediatric patients.
    British journal of clinical pharmacology, 1981, Volume: 12, Issue:6

    Topics: Adult; Female; Follicle Stimulating Hormone; Gonadotropins; Humans; Luteinizing Hormone; Male; Prola

1981
["Fever convulsions" in children. Current viewpoints on diagnosis, therapy and prognosis].
    Fortschritte der Medizin, 1982, Jun-24, Volume: 100, Issue:24

    Topics: Child, Preschool; Diagnosis, Differential; Diazepam; Epilepsy; Humans; Infant; Parents; Phenobarbita

1982
[Treatment of febrile convulsions in infants].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1995, Volume: 2, Issue:8

    Topics: Anticonvulsants; Diazepam; Humans; Infant; Recurrence; Seizures, Febrile; Valproic Acid

1995
[Risk factors in recurrent febrile seizures].
    Revista de neurologia, 1996, Volume: 24, Issue:136

    Topics: Child, Preschool; Electroencephalography; Female; Humans; Infant; Male; Recurrence; Retrospective St

1996
Hypothermia and thermoregulatory derangements induced by valproic acid.
    Neurology, 2001, Jan-09, Volume: 56, Issue:1

    Topics: Anticonvulsants; Body Temperature Regulation; Child, Preschool; Humans; Hypothermia; Male; Seizures,

2001
Treatment of febrile seizures: the influence of treatment efficacy and side-effect profile on value to parents.
    Pediatrics, 2001, Volume: 108, Issue:5

    Topics: Adult; Anticonvulsants; Anxiety; Attitude; Child, Preschool; Diazepam; Educational Status; Female; H

2001
[Treatment of febrile convulsions].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2002, Volume: 9, Issue:1

    Topics: Age Factors; Analgesics, Non-Narcotic; Anticonvulsants; Carbamazepine; Child, Preschool; Diazepam; D

2002
Febrile seizures and thalamocortical activity: a comparison of effects of valproate and phenytoin.
    Transactions of the American Neurological Association, 1979, Volume: 104

    Topics: Animals; Cats; Cerebral Cortex; Neural Pathways; Phenytoin; Seizures; Seizures, Febrile; Thalamus; V

1979
A comparative study of the efficacy of newer antiepiletpic drugs on experimentally-induced febrile convulsions.
    Neuropharmacology, 1977, Volume: 16, Issue:11

    Topics: Animals; Anticonvulsants; Body Temperature; Carbamazepine; Clonazepam; Male; Mice; Phenobarbital; Se

1977
Sixth-month benign familial convulsions.
    Epilepsy research. Supplement, 1992, Volume: 6

    Topics: Electroencephalography; Epilepsies, Partial; Female; Follow-Up Studies; Humans; Infant; Male; Phenob

1992
[Possible uses of Convulsofin liquid in the treatment of pediatric epilepsies].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1986, Volume: 38, Issue:3

    Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Epilepsies, Myoclonic; Epilepsies, Partia

1986
Serum valproate concentrations in epileptic children with favourable responses.
    Brain & development, 1987, Volume: 9, Issue:3

    Topics: Adolescent; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilepsies, Partial; Epilepsy

1987
Valproate monotherapy in children.
    The American journal of medicine, 1988, Jan-25, Volume: 84, Issue:1A

    Topics: Anticonvulsants; Child; Drug Therapy, Combination; Epilepsies, Myoclonic; Epilepsy; Epilepsy, Absenc

1988
[Prognosis of complicated febrile convulsions in therapy with primidone, cathine-phenobarbital and calcium valproinate].
    Kinderarztliche Praxis, 1988, Volume: 56, Issue:10

    Topics: Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Male; Phenobarbital; Phe

1988
[Use of sodium valproate in children].
    Pediatriia, 1985, Issue:7

    Topics: Epilepsy; Humans; Infant; Seizures, Febrile; Valproic Acid

1985