valproic acid has been researched along with Scleroderma, Localized in 3 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Scleroderma, Localized: A term used to describe a variety of localized asymmetrical SKIN thickening that is similar to those of SYSTEMIC SCLERODERMA but without the disease features in the multiple internal organs and BLOOD VESSELS. Lesions may be characterized as patches or plaques (morphea), bands (linear), or nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Morphea, a specific type of cutaneous sclerosis, is known in the pediatric age group, but not as an adverse effect to the antiepileptic valproic acid." | 1.32 | Localized morphea: a rare adverse effect of valproic acid. ( El-Tal, Ael-K; Ferzli, GT; Kibbi, AG; Mikati, MA, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Slimani, S | 1 |
| Hounas, F | 1 |
| Ladjouze-Rezig, A | 1 |
| Ferzli, GT | 1 |
| El-Tal, Ael-K | 1 |
| Kibbi, AG | 1 |
| Mikati, MA | 1 |
| Goihman-Yahr, M | 1 |
| Leal, G | 1 |
| Essenfeld-Yahr, E | 1 |
3 other studies available for valproic acid and Scleroderma, Localized
| Article | Year |
|---|---|
Multiple linear sclerodermas with a diffuse Parry-Romberg syndrome.
Topics: Child; Facial Hemiatrophy; Female; Humans; Scleroderma, Localized; Valproic Acid | 2009 |
Localized morphea: a rare adverse effect of valproic acid.
Topics: Adolescent; Humans; Male; Scleroderma, Localized; Valproic Acid | 2003 |
Generalized morphea: a side effect of valproate sodium?
Topics: Child; Epilepsy, Absence; Female; Humans; Scleroderma, Localized; Valproic Acid | 1980 |