Page last updated: 2024-10-26

valproic acid and Retinal Diseases

valproic acid has been researched along with Retinal Diseases in 7 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Retinal Diseases: Diseases involving the RETINA.

Research Excerpts

ExcerptRelevanceReference
"Vigabatrin acts as an inhibitor of gamma-aminobutyric acid (GABA) transaminase."1.30Outer retinal dysfunction in patients treated with vigabatrin. ( Arndt, CF; Defoort-Dhellemmes, S; Derambure, P; Hache, JC, 1999)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iizuka, N1
Morita, A1
Kawano, C1
Mori, A1
Sakamoto, K1
Kuroyama, M1
Ishii, K1
Nakahara, T1
Zhang, Z1
Qin, X1
Tong, N1
Zhao, X1
Gong, Y1
Shi, Y1
Wu, X1
Zhang, ZZ1
Wu, XW1
Gong, YY1
Zhang, W1
Yin, LL1
Lobefalo, L1
Rapinese, M1
Altobelli, E1
Di Mascio, R1
Lattanzi, D1
Gallenga, PE1
Chiarelli, F1
Verrotti, A1
Nizamie, SH1
Chatterjee, S1
Arndt, CF1
Derambure, P1
Defoort-Dhellemmes, S1
Hache, JC1
Ozkul, Y1
Gurler, B1
Uckardes, A1
Bozlar, S1

Other Studies

7 other studies available for valproic acid and Retinal Diseases

ArticleYear
Anti-angiogenic effects of valproic acid in a mouse model of oxygen-induced retinopathy.
    Journal of pharmacological sciences, 2018, Volume: 138, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Disease Models, Animal; Mice; Neovascularization, Pathologic; Oxyg

2018
Valproic acid-mediated neuroprotection in retinal ischemia injury via histone deacetylase inhibition and transcriptional activation.
    Experimental eye research, 2012, Volume: 94, Issue:1

    Topics: Acetylation; Animals; Apoptosis; Apoptotic Protease-Activating Factor 1; Axons; Caspase 3; Cytochrom

2012
[Protective effect of valproic acid on ischemia-reperfusion induced injury in retina of rat].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2012, Volume: 48, Issue:8

    Topics: Animals; bcl-2-Associated X Protein; HSP70 Heat-Shock Proteins; Male; Proto-Oncogene Proteins c-bcl-

2012
Retinal nerve fiber layer and macular thickness in adolescents with epilepsy treated with valproate and carbamazepine.
    Epilepsia, 2006, Volume: 47, Issue:4

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Color Vision Defects; Epilepsy; Female; Follow-Up

2006
Affective psychosis in Eales' disease and response to sodium valproate.
    General hospital psychiatry, 1994, Volume: 16, Issue:5

    Topics: Adult; Affective Disorders, Psychotic; Combined Modality Therapy; Electroconvulsive Therapy; Humans;

1994
Outer retinal dysfunction in patients treated with vigabatrin.
    Neurology, 1999, Apr-12, Volume: 52, Issue:6

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Electrooculography; Electroretinography; Epilepsies

1999
Visual functions in epilepsy patients on valproate monotherapy.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2002, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Electroretinography; Epilepsy; Female; Humans; Male; Reference V

2002