valproic acid has been researched along with Respiratory Insufficiency in 9 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Respiratory Insufficiency: Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "An open-label, randomized controlled study was conducted at a tertiary care teaching hospital to compare efficacy and safety of intravenous sodium valproate versus diazepam infusion for control of refractory status epilepticus." | 9.12 | Intravenous sodium valproate versus diazepam infusion for the control of refractory status epilepticus in children: a randomized controlled trial. ( Mehta, V; Singhi, P; Singhi, S, 2007) |
| "No patient in the VPA group developed respiratory depression, hypotension, or hepatic dysfunction, whereas in the DZP group, 5." | 6.76 | Valproate versus diazepam for generalized convulsive status epilepticus: a pilot study. ( Chen, WB; Fan, CQ; Gao, R; Ren, Y; Su, YY; Wang, L; Zhang, YZ; Zhao, JW, 2011) |
| "Valproic acid (VPA) has shown potent anti-inflammatory effect and attenuates acute lung injury." | 5.48 | Valproic acid attenuates the risk of acute respiratory failure in patients with subarachnoid hemorrhage. ( Chien, WC; Chu, SJ; Chung, CH; Chung, TT; Liao, WI; Tsai, SH; Wang, JC, 2018) |
| "Behavior, seizures, death, EEGs, and ECGs were observed and measured." | 5.28 | Cocaine-induced respiratory depression and seizures are synergistic mechanisms of cocaine-induced death in rats. ( Albertson, TE; Derlet, RW; Tseng, CC, 1992) |
| "An open-label, randomized controlled study was conducted at a tertiary care teaching hospital to compare efficacy and safety of intravenous sodium valproate versus diazepam infusion for control of refractory status epilepticus." | 5.12 | Intravenous sodium valproate versus diazepam infusion for the control of refractory status epilepticus in children: a randomized controlled trial. ( Mehta, V; Singhi, P; Singhi, S, 2007) |
| "No patient in the VPA group developed respiratory depression, hypotension, or hepatic dysfunction, whereas in the DZP group, 5." | 2.76 | Valproate versus diazepam for generalized convulsive status epilepticus: a pilot study. ( Chen, WB; Fan, CQ; Gao, R; Ren, Y; Su, YY; Wang, L; Zhang, YZ; Zhao, JW, 2011) |
| "Valproic acid (VPA) has shown potent anti-inflammatory effect and attenuates acute lung injury." | 1.48 | Valproic acid attenuates the risk of acute respiratory failure in patients with subarachnoid hemorrhage. ( Chien, WC; Chu, SJ; Chung, CH; Chung, TT; Liao, WI; Tsai, SH; Wang, JC, 2018) |
| "Behavior, seizures, death, EEGs, and ECGs were observed and measured." | 1.28 | Cocaine-induced respiratory depression and seizures are synergistic mechanisms of cocaine-induced death in rats. ( Albertson, TE; Derlet, RW; Tseng, CC, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Bataineh, AM | 1 |
| Yassin, A | 1 |
| El-Salem, K | 1 |
| Bashayreh, SY | 1 |
| Alhayk, KA | 1 |
| Al Qawasmeh, M | 1 |
| Kofahi, RM | 1 |
| Al-Mistarehi, AH | 1 |
| Liao, WI | 1 |
| Chien, WC | 1 |
| Chung, CH | 1 |
| Wang, JC | 1 |
| Chung, TT | 1 |
| Chu, SJ | 1 |
| Tsai, SH | 1 |
| Amathieu, R | 1 |
| Levesque, E | 1 |
| Merle, JC | 1 |
| Chemit, M | 1 |
| Costentin, C | 1 |
| Compagnon, P | 1 |
| Dhonneur, G | 1 |
| Presecki, P | 1 |
| Grosić, V | 1 |
| Silić, A | 1 |
| Mihanović, M | 1 |
| Chen, WB | 1 |
| Gao, R | 1 |
| Su, YY | 1 |
| Zhao, JW | 1 |
| Zhang, YZ | 1 |
| Wang, L | 1 |
| Ren, Y | 1 |
| Fan, CQ | 1 |
| Mehta, V | 1 |
| Singhi, P | 1 |
| Singhi, S | 1 |
| Sikma, MA | 1 |
| Mier, JC | 1 |
| Meulenbelt, J | 1 |
| Trehan, R | 1 |
| Clark, CF | 1 |
| Tseng, CC | 1 |
| Derlet, RW | 1 |
| Albertson, TE | 1 |
1 review available for valproic acid and Respiratory Insufficiency
| Article | Year |
|---|---|
[Severe toxic acute liver failure: etiology and treatment].
Topics: Acetaminophen; Acetylcysteine; Acute Kidney Injury; Anti-Infective Agents; Blood Coagulation Disorde | 2013 |
2 trials available for valproic acid and Respiratory Insufficiency
| Article | Year |
|---|---|
Valproate versus diazepam for generalized convulsive status epilepticus: a pilot study.
Topics: Adult; Aged; Anticonvulsants; Cerebrovascular Disorders; Diazepam; Drug Resistance; Electroencephalo | 2011 |
Intravenous sodium valproate versus diazepam infusion for the control of refractory status epilepticus in children: a randomized controlled trial.
Topics: Anticonvulsants; Child; Child, Preschool; Diazepam; Female; Humans; Hypotension; Infant; Infusions, | 2007 |
6 other studies available for valproic acid and Respiratory Insufficiency
| Article | Year |
|---|---|
A 73-Year-Old Woman with Respiratory Failure and Stimulus-Induced Rhythmic, Periodic, or Ictal Discharges (SIRPIDs) in the Absence of a Detectable Brain Insult Diagnosed and Monitored by Continuous Electroencephalogram (EEG) and Treated with Valproate, Ca
Topics: Aged; Brain; Carbamazepine; Clonazepam; Electroencephalography; Female; Humans; Patient Discharge; R | 2021 |
Valproic acid attenuates the risk of acute respiratory failure in patients with subarachnoid hemorrhage.
Topics: Acute Disease; Adult; Aged; Anti-Inflammatory Agents; Databases, Factual; Female; Humans; Incidence; | 2018 |
Infection or idiosyncratic reaction to antiepileptic drugs?
Topics: Adult; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Clozapine; Diagnosis, Differential; | 2010 |
Massive valproic acid overdose, a misleading case.
Topics: Adult; Ammonia; Anticonvulsants; Antidotes; Charcoal; Coma; Drug Overdose; Epilepsy; Humans; Male; P | 2008 |
Valproic acid-induced truncal weakness and respiratory failure.
Topics: Aged; Bipolar Disorder; Drug Therapy, Combination; Humans; Male; Muscular Diseases; Respiratory Insu | 1993 |
Cocaine-induced respiratory depression and seizures are synergistic mechanisms of cocaine-induced death in rats.
Topics: Animals; Cocaine; Death; Dizocilpine Maleate; Drug Synergism; Electrocardiography; Electroencephalog | 1992 |