valproic acid has been researched along with Renal Insufficiency, Chronic in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Renal Insufficiency, Chronic: Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To quantify absolute and relative risks of chronic kidney disease (CKD) progression and acute kidney injury (AKI) in people who initiated lithium compared with valproate therapy and to investigate the association between cumulative use and elevated lithium levels and kidney outcomes." | 4.31 | Absolute and Relative Risks of Kidney Outcomes Associated With Lithium vs Valproate Use in Sweden. ( Bellocco, R; Bosi, A; Carrero, JJ; Ceriani, L; Chang, Z; Clase, CM; Elinder, CG; Fu, EL; Landén, M; Runesson, B; Sjölander, A, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Damba, JJ | 1 |
| Bodenstein, K | 1 |
| Lavin, P | 1 |
| Drury, J | 1 |
| Sekhon, H | 1 |
| Renoux, C | 1 |
| Trinh, E | 1 |
| Rej, S | 1 |
| Greenway, KT | 1 |
| Bosi, A | 1 |
| Clase, CM | 1 |
| Ceriani, L | 1 |
| Sjölander, A | 1 |
| Fu, EL | 1 |
| Runesson, B | 1 |
| Chang, Z | 1 |
| Landén, M | 1 |
| Bellocco, R | 1 |
| Elinder, CG | 1 |
| Carrero, JJ | 1 |
1 review available for valproic acid and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Psychotropic Drugs and Adverse Kidney Effects: A Systematic Review of the Past Decade of Research.
Topics: Aged; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Diabetes Insipi | 2022 |
1 other study available for valproic acid and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Absolute and Relative Risks of Kidney Outcomes Associated With Lithium vs Valproate Use in Sweden.
Topics: Acute Kidney Injury; Adult; Albuminuria; Cohort Studies; Creatinine; Female; Humans; Kidney; Lithium | 2023 |