valproic acid has been researched along with Psychoses, Drug in 13 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this preliminary report from a placebo-controlled, double-blind, dose-response study on the use of pergolide mesylate for cocaine dependence in outpatients 8 out of 235 subjects noted adverse events requiring breaking of the blind." | 2.68 | Pergolide mesylate. Adverse events occurring in the treatment of cocaine dependence. ( Cochrane, CE; Kajdasz, DK; Malcolm, R; Moore, JW, 1997) |
| " A final dosage of 60 mg/kg was used." | 1.32 | Acute psychosis associated with levetiracetam. ( Karagianni, J; Lazopoulou, D; Michelakou, D; Youroukos, S, 2003) |
| "Seven patients with refractory seizure disorders and neuropsychiatric symptoms believed secondary to felbamate are presented." | 1.29 | Neuropsychiatric side effects related to treatment with felbamate. ( Brillman, J; Cavalier, J; Cress, K; Duffy, JD; McConnell, H; Snyder, PJ; Valeriano, J; Weilburg, J, 1996) |
| "Valproic acid is infrequently used for treatment of psychosis." | 1.28 | Neuroleptic-valproic acid combination in treatment of psychotic symptoms: a three-case report. ( Bryant, S; Flack, J; Morrison, P; Wassef, A; Watson, DJ, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (53.85) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gupta, P | 1 |
| Tundup, T | 1 |
| Singh, J | 1 |
| Deb, KS | 1 |
| Verma, R | 1 |
| Kumar, N | 1 |
| Pope, JD | 1 |
| Choy, KW | 1 |
| Drummer, OH | 1 |
| Schneider, HG | 1 |
| Youroukos, S | 1 |
| Lazopoulou, D | 1 |
| Michelakou, D | 1 |
| Karagianni, J | 1 |
| Reynolds, EH | 1 |
| Parajua, JL | 1 |
| Goñi, M | 1 |
| Feijoo, M | 1 |
| Diehl, LW | 1 |
| Abbas, A | 1 |
| Styra, R | 1 |
| McConnell, H | 1 |
| Snyder, PJ | 1 |
| Duffy, JD | 1 |
| Weilburg, J | 1 |
| Valeriano, J | 1 |
| Brillman, J | 1 |
| Cress, K | 1 |
| Cavalier, J | 1 |
| Malcolm, R | 1 |
| Moore, JW | 1 |
| Kajdasz, DK | 1 |
| Cochrane, CE | 1 |
| Bellmann, MH | 1 |
| Ross, EM | 1 |
| McKee, RJ | 1 |
| Larkin, JG | 1 |
| Brodie, MJ | 1 |
| Wassef, A | 1 |
| Watson, DJ | 1 |
| Morrison, P | 1 |
| Bryant, S | 1 |
| Flack, J | 1 |
| Shukla, S | 1 |
| Turner, WJ | 1 |
| Newman, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Dose Response Trial of Pergolide for Cocaine Dependence[NCT00000248] | Phase 3 | 0 participants | Interventional | 1996-02-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for valproic acid and Psychoses, Drug
| Article | Year |
|---|---|
Mental effects of antiepileptic medication: a review.
Topics: Adolescent; Adult; Anticonvulsants; Attention; Barbiturates; Brain Chemistry; Carbamazepine; Child; | 1983 |
1 trial available for valproic acid and Psychoses, Drug
| Article | Year |
|---|---|
Pergolide mesylate. Adverse events occurring in the treatment of cocaine dependence.
Topics: Adult; Antimanic Agents; Cardiovascular Physiological Phenomena; Cardiovascular System; Cocaine; Dop | 1997 |
11 other studies available for valproic acid and Psychoses, Drug
| Article | Year |
|---|---|
Treatment complexities in psychosis associated with cabergoline treatment in patients having pituitary prolactinomas.
Topics: Adult; Cabergoline; Dopamine Agonists; Female; GABA Agents; Humans; Pituitary Neoplasms; Prolactinom | 2018 |
Harmala Alkaloids Identify Ayahausca Intoxication in a Urine Drug Screen.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Banisteriopsis; Chromatography, Liquid; Hallucinogens | 2019 |
Acute psychosis associated with levetiracetam.
Topics: Anticonvulsants; Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy | 2003 |
[Psychotic behavior induced by valproic acid].
Topics: Adult; Female; Humans; Psychoses, Substance-Induced; Valproic Acid | 1984 |
[Complications of valproic acid therapy: an overview (author's transl)].
Topics: Adult; Alcohol Withdrawal Delirium; Chemical and Drug Induced Liver Injury; Child; Coma; Electroence | 1981 |
Valproate prophylaxis against steroid induced psychosis.
Topics: Adult; Bipolar Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans | 1994 |
Neuropsychiatric side effects related to treatment with felbamate.
Topics: Adult; Anticonvulsants; Drug Interactions; Felbamate; Female; Humans; Male; Middle Aged; Phenylcarba | 1996 |
Side effects of sodium valproate.
Topics: Adolescent; Humans; Male; Psychoses, Substance-Induced; Valerates; Valproic Acid | 1977 |
Acute psychosis with carbamazepine and sodium valproate.
Topics: Acute Disease; Adult; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy, Tempora | 1989 |
Neuroleptic-valproic acid combination in treatment of psychotic symptoms: a three-case report.
Topics: Adult; Antipsychotic Agents; Drug Therapy, Combination; Female; Hallucinations; Humans; Male; Middle | 1989 |
Bromocriptine-related psychosis and treatment.
Topics: Adult; Bromocriptine; Female; Haloperidol; Humans; Pituitary Neoplasms; Prolactin; Psychoses, Substa | 1985 |