Page last updated: 2024-10-26

valproic acid and Primary Myelofibrosis

valproic acid has been researched along with Primary Myelofibrosis in 1 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Primary Myelofibrosis: A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Inoue, Y1
Suzuki, T1
Takimoto, M1
Irei, M1
Yoshioka, S1
Shibuya, Y1
Kato, M1
Koike, M1
Takahashi, M1

Other Studies

1 other study available for valproic acid and Primary Myelofibrosis

ArticleYear
Treatment with valproic acid for myelofibrosis with myeloid metaplasia.
    Annals of hematology, 2005, Volume: 84, Issue:12

    Topics: Aged; Anticonvulsants; Blood Cell Count; Epilepsy; Female; Hemorrhage; Humans; Primary Myelofibrosis

2005