valproic acid has been researched along with Porphyria, Acute Intermittent in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Porphyria, Acute Intermittent: An autosomal dominant porphyria that is due to a deficiency of HYDROXYMETHYLBILANE SYNTHASE in the LIVER, the third enzyme in the 8-enzyme biosynthetic pathway of HEME. Clinical features are recurrent and life-threatening neurologic disturbances, ABDOMINAL PAIN, and elevated level of AMINOLEVULINIC ACID and PORPHOBILINOGEN in the urine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute intermittent porphyria is an autosomal dominant inborn error of heme biosynthesis." | 1.30 | [Acute intermittent porphyria associated with epilepsy in a child: diagnostic and therapeutic difficulties]. ( Carrière, JP; Chaix, Y; Gencourt, C; Grouteau, E, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Noval Menéndez, J | 1 |
| Campoamor, MT | 1 |
| Laborda, B | 1 |
| López-Colina, G | 1 |
| Chaix, Y | 1 |
| Gencourt, C | 1 |
| Grouteau, E | 1 |
| Carrière, JP | 1 |
2 other studies available for valproic acid and Porphyria, Acute Intermittent
| Article | Year |
|---|---|
[Acute Intermittent porphyria and valproic acid].
Topics: Anticonvulsants; Female; Humans; Middle Aged; Porphyria, Acute Intermittent; Seizures; Valproic Acid | 2012 |
[Acute intermittent porphyria associated with epilepsy in a child: diagnostic and therapeutic difficulties].
Topics: Anticonvulsants; Child; Clonazepam; Drug Therapy, Combination; Epilepsies, Partial; Humans; Male; Po | 1997 |