Page last updated: 2024-10-26

valproic acid and Pneumonia

valproic acid has been researched along with Pneumonia in 8 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Pneumonia: Infection of the lung often accompanied by inflammation.

Research Excerpts

ExcerptRelevanceReference
" In the present study, VPA in combination with two differentiating agents, 13-cis retinoic acid and 1,25-dihydroxyvitamin D3, was given to 19 previously untreated patients with MDS or CMML."6.73Valproic acid combined with 13-cis retinoic acid and 1,25-dihydroxyvitamin D3 in the treatment of patients with myelodysplastic syndromes. ( Hallman, H; Honkanen, T; Juvonen, E; Kauppila, M; Koistinen, P; Kutila, A; Mikkola, M; Nyländen, P; Poikonen, E; Rauhala, A; Savolainen, ER; Siitonen, T; Sinisalo, M; Suominen, M; Terävä, V; Timonen, T, 2007)
"Valproic acid (VPA) has shown potent anti-inflammatory effect and attenuates acute lung injury."5.48Valproic acid attenuates the risk of acute respiratory failure in patients with subarachnoid hemorrhage. ( Chien, WC; Chu, SJ; Chung, CH; Chung, TT; Liao, WI; Tsai, SH; Wang, JC, 2018)
"This report describes an 85-year-old Chinese male inpatient who twice received concomitant administration of meropenem and valproic acid for the treatment of pneumonia and poststroke epilepsy, respectively."3.75Effect of concomitant administration of meropenem and valproic acid in an elderly Chinese patient. ( Gu, J; Huang, Y, 2009)
"A 55-year-old woman was diagnosed with pneumonia and was treated with meropenem; 5 days later she developed epileptic seizures."3.73Epileptic seizures caused by low valproic acid levels from an interaction with meropenem. ( Carcas, A; Fudio, S; Ortega, R; Piñana, E, 2006)
" In the present study, VPA in combination with two differentiating agents, 13-cis retinoic acid and 1,25-dihydroxyvitamin D3, was given to 19 previously untreated patients with MDS or CMML."2.73Valproic acid combined with 13-cis retinoic acid and 1,25-dihydroxyvitamin D3 in the treatment of patients with myelodysplastic syndromes. ( Hallman, H; Honkanen, T; Juvonen, E; Kauppila, M; Koistinen, P; Kutila, A; Mikkola, M; Nyländen, P; Poikonen, E; Rauhala, A; Savolainen, ER; Siitonen, T; Sinisalo, M; Suominen, M; Terävä, V; Timonen, T, 2007)
"Valproic acid (VPA) has shown potent anti-inflammatory effect and attenuates acute lung injury."1.48Valproic acid attenuates the risk of acute respiratory failure in patients with subarachnoid hemorrhage. ( Chien, WC; Chu, SJ; Chung, CH; Chung, TT; Liao, WI; Tsai, SH; Wang, JC, 2018)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (50.00)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liao, WI1
Chien, WC1
Chung, CH1
Wang, JC1
Chung, TT1
Chu, SJ1
Tsai, SH1
Yang, SY1
Liao, YT1
Liu, HC1
Chen, WJ1
Chen, CC1
Kuo, CJ1
Nagai, Y1
Limberis, MP1
Zhang, H1
Gu, J1
Huang, Y1
Kochanek, AR1
Fukudome, EY1
Li, Y1
Smith, EJ1
Liu, B1
Velmahos, GC1
deMoya, M1
King, D1
Alam, HB1
Bourgeois, JA1
Koike, AK1
Simmons, JE1
Telles, S1
Eggleston, C1
Fudio, S1
Carcas, A1
Piñana, E1
Ortega, R1
Siitonen, T1
Timonen, T1
Juvonen, E1
Terävä, V1
Kutila, A1
Honkanen, T1
Mikkola, M1
Hallman, H1
Kauppila, M1
Nyländen, P1
Poikonen, E1
Rauhala, A1
Sinisalo, M1
Suominen, M1
Savolainen, ER1
Koistinen, P1

Trials

1 trial available for valproic acid and Pneumonia

ArticleYear
Valproic acid combined with 13-cis retinoic acid and 1,25-dihydroxyvitamin D3 in the treatment of patients with myelodysplastic syndromes.
    Haematologica, 2007, Volume: 92, Issue:8

    Topics: Acetylation; Aged; Aged, 80 and over; Calcitriol; Cheilitis; Chemical and Drug Induced Liver Injury;

2007

Other Studies

7 other studies available for valproic acid and Pneumonia

ArticleYear
Valproic acid attenuates the risk of acute respiratory failure in patients with subarachnoid hemorrhage.
    QJM : monthly journal of the Association of Physicians, 2018, Feb-01, Volume: 111, Issue:2

    Topics: Acute Disease; Adult; Aged; Anti-Inflammatory Agents; Databases, Factual; Female; Humans; Incidence;

2018
Antipsychotic drugs, mood stabilizers, and risk of pneumonia in bipolar disorder: a nationwide case-control study.
    The Journal of clinical psychiatry, 2013, Volume: 74, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar

2013
Modulation of Treg function improves adenovirus vector-mediated gene expression in the airway.
    Gene therapy, 2014, Volume: 21, Issue:2

    Topics: Adaptive Immunity; Animals; Cystic Fibrosis; Dependovirus; Disease Models, Animal; Gene Transfer Tec

2014
Effect of concomitant administration of meropenem and valproic acid in an elderly Chinese patient.
    The American journal of geriatric pharmacotherapy, 2009, Volume: 7, Issue:1

    Topics: Aged, 80 and over; Anti-Bacterial Agents; Anticonvulsants; Drug Administration Schedule; Drug Intera

2009
Histone deacetylase inhibitor treatment attenuates MAP kinase pathway activation and pulmonary inflammation following hemorrhagic shock in a rodent model.
    The Journal of surgical research, 2012, Volume: 176, Issue:1

    Topics: Animals; Apoptosis; Disease Models, Animal; Histone Deacetylase Inhibitors; Lung; Male; Mitogen-Acti

2012
Adjunctive valproic acid for delirium and/or agitation on a consultation-liaison service: a report of six cases.
    The Journal of neuropsychiatry and clinical neurosciences, 2005,Spring, Volume: 17, Issue:2

    Topics: Alcohol Withdrawal Delirium; Alcoholism; Anticonvulsants; Delirium; Fever; Humans; Injections, Intra

2005
Epileptic seizures caused by low valproic acid levels from an interaction with meropenem.
    Journal of clinical pharmacy and therapeutics, 2006, Volume: 31, Issue:4

    Topics: Anticonvulsants; Drug Interactions; Epilepsy; Female; Humans; Meropenem; Middle Aged; Pneumonia; Thi

2006