Page last updated: 2024-10-26

valproic acid and Pleural Effusion

valproic acid has been researched along with Pleural Effusion in 17 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Pleural Effusion: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.

Research Excerpts

ExcerptRelevanceReference
"We present a case of eosinophilic pleural effusion due to valproic acid (VPA), a rare adverse event that has been reported previously."8.88Valproic acid-induced eosinophilic pleural effusion: a case report and review of the literature. ( Da'as, N; Esayag, Y; Kamenetsky, Z; Kleinman, Y; Samuels, N, 2012)
" We report on the case of a 40-year-old man who experienced an eosinophilic pleural effusion with blood hypereosinophilia that occurred nine weeks after a treatment with valproic acid was introduced."7.77[Eosinophilic pleural effusion related to taking valproic acid]. ( Bally, C; Burgel, PR; Dusser, D; Kanaan, R; Kraoua, S; Lacronique, J; Martin, C, 2011)
"To report a case of valproic acid-induced eosinophilic pleural effusion and to review the existing literature."7.74Valproic acid-induced eosinophilic pleural effusion: a case report and review of the literature. ( Bullington, W; Judson, MA; Sahn, SA, 2007)
"Valproic acid is a carboxylic acid used for the treatment of both seizure and mood disorders."5.32Valproic acid-induced eosinophilic pleural effusion. ( Federman, DG; Kravetz, JD, 2003)
"Valproate-induced pleural effusion is rare, but patients receiving treatment with valproic acid who develop respiratory symptoms should be examined for valproate-induced pleural effusion."5.12Clinical and pathophysiological characteristics of valproate-induced pleural effusion. ( Georgopoulou, A; Ismailos, G; Papadopoulou, E; Saroglou, M; Serasli, E; Tryfon, S; Vlachopoulos, D, 2021)
"We present a case of eosinophilic pleural effusion due to valproic acid (VPA), a rare adverse event that has been reported previously."4.88Valproic acid-induced eosinophilic pleural effusion: a case report and review of the literature. ( Da'as, N; Esayag, Y; Kamenetsky, Z; Kleinman, Y; Samuels, N, 2012)
" We report on the case of a 40-year-old man who experienced an eosinophilic pleural effusion with blood hypereosinophilia that occurred nine weeks after a treatment with valproic acid was introduced."3.77[Eosinophilic pleural effusion related to taking valproic acid]. ( Bally, C; Burgel, PR; Dusser, D; Kanaan, R; Kraoua, S; Lacronique, J; Martin, C, 2011)
"To report a case of valproic acid-induced eosinophilic pleural effusion and to review the existing literature."3.74Valproic acid-induced eosinophilic pleural effusion: a case report and review of the literature. ( Bullington, W; Judson, MA; Sahn, SA, 2007)
"A child with dyskinetic cerebral palsy who had been on sodium valproate for several years was transferred for drainage of a left sided pleural effusion."1.35Fungal pleural effusion secondary to a rare cause of pancreatic pseudocyst. ( Bush, A; Clarke, S; Gupta, A; Marrs, T; Rosenthal, M; Urquhart, D, 2009)
"Valproic acid is a carboxylic acid used for the treatment of both seizure and mood disorders."1.32Valproic acid-induced eosinophilic pleural effusion. ( Federman, DG; Kravetz, JD, 2003)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.88)18.2507
2000's6 (35.29)29.6817
2010's6 (35.29)24.3611
2020's4 (23.53)2.80

Authors

AuthorsStudies
Agossou, M1
Venissac, N1
Demir, UF1
Zhang, G1
Tryfon, S1
Papadopoulou, E1
Saroglou, M1
Vlachopoulos, D1
Georgopoulou, A1
Serasli, E1
Ismailos, G1
Aral, A1
Usta, MB1
Karabekiroglu, K1
Taşer, N1
Sarıkaya, M1
San Miguel López de Uralde, SM1
Prieto Peraita, M1
Blanco Bengoechea, EJ1
Gupta, A1
Marrs, T1
Urquhart, D1
Clarke, S1
Rosenthal, M1
Bush, A1
Fernández-Pérez, R1
Alvarez-Dobaño, JM1
Suárez-Antelo, J1
Codesido-Barcala, R1
Carballal-Calvo, F1
Arrojo-Romero, M1
de Leon, J1
Abdelhamid, MS1
Percival, M1
Sivakumaran, P1
Bally, C1
Martin, C1
Kraoua, S1
Kanaan, R1
Lacronique, J1
Dusser, D1
Burgel, PR1
Kamenetsky, Z1
Da'as, N1
Esayag, Y1
Kleinman, Y1
Samuels, N1
Kravetz, JD1
Federman, DG1
Bhatti, MA1
Zander, J1
Reeve, E1
Bullington, W1
Sahn, SA1
Judson, MA1
Kaufman, J1
O'Shaughnessy, IM1
Tonnelier, JM1
Mocquard, Y1
Broch, C1
Vandhuick, O1
Goas, P1
Goas, JY1

Reviews

3 reviews available for valproic acid and Pleural Effusion

ArticleYear
Valproic acid-induced eosinophilic pleural effusion: A case report and brief review.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2020, Volume: 32, Issue:4

    Topics: Aged; Eosinophils; Humans; Male; Pleural Effusion; Valproic Acid

2020
Clinical and pathophysiological characteristics of valproate-induced pleural effusion.
    Clinical toxicology (Philadelphia, Pa.), 2021, Volume: 59, Issue:10

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Eosinophilia; Female; Humans; Lupus Erythematosus, Systemi

2021
Valproic acid-induced eosinophilic pleural effusion: a case report and review of the literature.
    The neurologist, 2012, Volume: 18, Issue:1

    Topics: Adult; Eosinophilia; Exudates and Transudates; Humans; Male; Pleural Effusion; Seizures; Valproic Ac

2012

Other Studies

14 other studies available for valproic acid and Pleural Effusion

ArticleYear
[Sodium valproate-induced pleural effusion: When it changes sides!]
    Revue des maladies respiratoires, 2022, Volume: 39, Issue:2

    Topics: Humans; Pleural Effusion; Pleurisy; Valproic Acid

2022
Valproic acid associated pleuropericardial effusion: case report.
    Ideggyogyaszati szemle, 2020, Jan-30, Volume: 73, Issue:1-2

    Topics: Anticonvulsants; Epilepsy; Female; Humans; Pericardial Effusion; Pleural Effusion; Valproic Acid; Yo

2020
Valproic acid-induced eosinophilic pleural effusion in a patient with pediatric bipolar disorder.
    Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists, 2017, Volume: 9, Issue:3

    Topics: Antimanic Agents; Bipolar Disorder; Child; Humans; Pleural Effusion; Valproic Acid

2017
An unusual case of pleuropericardial neutrophilic effusion associated with valproate.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2015, Volume: 114, Issue:4

    Topics: Adult; Cough; Dyspnea; Echocardiography; Epilepsy; Female; Humans; Pericardial Effusion; Pericardioc

2015
[Pulmonary eosinophilia associated with valproic acid].
    Medicina clinica, 2015, Jun-08, Volume: 144, Issue:11

    Topics: Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Anxiety Disorders; Bronchoalveolar Lavage Flu

2015
Fungal pleural effusion secondary to a rare cause of pancreatic pseudocyst.
    Pediatric pulmonology, 2009, Volume: 44, Issue:6

    Topics: Anticonvulsants; Candida glabrata; Candidiasis; Cerebral Palsy; Child, Preschool; Female; Humans; Ia

2009
Eosinophilic pleural effusion associated with the addition of sodium valproate.
    Journal of clinical psychopharmacology, 2009, Volume: 29, Issue:3

    Topics: Antimanic Agents; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Eosinophilia; Female;

2009
Sodium valproate - a rare cause of eosinophilic pleural effusion.
    Internal medicine journal, 2011, Volume: 41, Issue:11

    Topics: Eosinophilia; Humans; Male; Middle Aged; Pleural Effusion; Valproic Acid

2011
[Eosinophilic pleural effusion related to taking valproic acid].
    Revue de pneumologie clinique, 2011, Volume: 67, Issue:6

    Topics: Adult; Antimanic Agents; Blood Cell Count; Eosinophilia; Eosinophils; Humans; Male; Pleural Effusion

2011
Valproic acid-induced eosinophilic pleural effusion.
    Southern medical journal, 2003, Volume: 96, Issue:8

    Topics: Adult; Anti-Bacterial Agents; Antimanic Agents; Ceftazidime; Chest Pain; Cough; Drainage; Drug Thera

2003
Clozapine-induced pericarditis, pericardial tamponade, polyserositis, and rash.
    The Journal of clinical psychiatry, 2005, Volume: 66, Issue:11

    Topics: Adult; Anticonvulsants; Antipsychotic Agents; Cardiac Tamponade; Clozapine; Drug Eruptions; Drug The

2005
Valproic acid-induced eosinophilic pleural effusion: a case report and review of the literature.
    The American journal of the medical sciences, 2007, Volume: 333, Issue:5

    Topics: Adult; Eosinophilia; Humans; Male; Pleural Effusion; Valproic Acid

2007
Eosinophilic pleural effusion associated with valproic acid administration.
    Southern medical journal, 1995, Volume: 88, Issue:8

    Topics: Adult; Epilepsy; Humans; Male; Pleural Effusion; Pulmonary Eosinophilia; Valproic Acid

1995
[Febrile pleuropericarditis during valproic acid treatment].
    Presse medicale (Paris, France : 1983), 2001, Jan-20, Volume: 30, Issue:2

    Topics: Anticonvulsants; Epilepsy; Female; Fever; Humans; Middle Aged; Pericarditis; Pleural Effusion; Valpr

2001