Page last updated: 2024-10-26

valproic acid and Peripheral Nerve Diseases

valproic acid has been researched along with Peripheral Nerve Diseases in 11 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

ExcerptRelevanceReference
" Reversible dystonia may occasionally be precipitated by phenytoin or carbamazepine; asterixis by phenytoin, barbiturates or carbamazepine; and, more commonly, tremor by valproate."4.77Adverse neuropsychiatric effects of anticonvulsant drugs. ( Reynolds, EH; Trimble, MR, 1985)
"Young adult outpatients with epilepsy on monotherapy for no less than 6 months with carbamazepine (CBZ), valproic acid (VPA), oxcarbazepine (OXC) and topiramate (TPM) were examined."3.76Effects of the antiepileptic drugs on peripheral nerve function. ( Boylu, E; Domaç, FM; Misirli, H; Saraçoğlu, M; Senol, MG, 2010)
" The neurologic symptoms resolved upon VPA dosage reduction."1.29Apparent valproic acid neurotoxicity in a hypoalbuminemic patient. ( Beinlich, BR; Collins, DM; Gidal, BE, 1993)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's2 (18.18)18.2507
2000's3 (27.27)29.6817
2010's3 (27.27)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Günay, Ç1
Edem, P1
Hız-Kurul, AS1
Yaşar, E1
Yiş, U1
Marusic, S1
Obreli Neto, PR1
Vuletic, V1
Kirin, M1
Wilimowska, J1
Kłys, M1
Jawień, W1
Rodriguez-Menendez, V1
Tremolizzo, L1
Cavaletti, G1
Boylu, E1
Domaç, FM1
Misirli, H1
Senol, MG1
Saraçoğlu, M1
Winkler, I2
Blotnik, S1
Shimshoni, J1
Yagen, B2
Devor, M2
Bialer, M2
Sobol, E1
Steinman, A1
Gidal, BE1
Collins, DM1
Beinlich, BR1
Skelton, WP1
Skelton, NR1
Reynolds, EH1
Trimble, MR1
Lipsky, MS1

Reviews

2 reviews available for valproic acid and Peripheral Nerve Diseases

ArticleYear
Targeting cancer and neuropathy with histone deacetylase inhibitors: two birds with one stone?
    Current cancer drug targets, 2008, Volume: 8, Issue:4

    Topics: Animals; Antineoplastic Agents; Cisplatin; Enzyme Inhibitors; Epigenesis, Genetic; Histone Deacetyla

2008
Adverse neuropsychiatric effects of anticonvulsant drugs.
    Drugs, 1985, Volume: 29, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Biogenic Amines; Carba

1985

Other Studies

9 other studies available for valproic acid and Peripheral Nerve Diseases

ArticleYear
Recurrent painful ophthalmoplegic neuropathy: a report of two new pediatric cases.
    The Turkish journal of pediatrics, 2022, Volume: 64, Issue:3

    Topics: Child; Child, Preschool; Female; Headache; Humans; Magnetic Resonance Imaging; Ophthalmoplegia; Opht

2022
Peripheral mononeuropathy associated with valproic acid poisoning in an adult patient.
    International journal of clinical pharmacology and therapeutics, 2014, Volume: 52, Issue:9

    Topics: Adult; Antimanic Agents; Bipolar Disorder; Drug Overdose; Humans; Male; Mononeuropathies; Neurologic

2014
Analysis of variability of concentrations of valproic acid (VPA) and its selected metabolites in the blood serum of patients treated with VPA and patients hospitalized because of VPA poisoning.
    Archiwum medycyny sadowej i kryminologii, 2014, Volume: 64, Issue:4

    Topics: Anticonvulsants; Bipolar Disorder; Drug Overdose; Epilepsy; Female; Humans; Male; Peripheral Nervous

2014
Effects of the antiepileptic drugs on peripheral nerve function.
    Acta neurologica Scandinavica, 2010, Volume: 121, Issue:1

    Topics: Anticonvulsants; Carbamazepine; Epilepsy; Female; Fructose; Humans; Male; Median Nerve; Neural Condu

2010
Efficacy of antiepileptic isomers of valproic acid and valpromide in a rat model of neuropathic pain.
    British journal of pharmacology, 2005, Volume: 146, Issue:2

    Topics: Analgesics; Animals; Anticonvulsants; Hyperalgesia; Isomerism; Ligation; Male; Pain; Pain Measuremen

2005
Efficacy of antiepileptic tetramethylcyclopropyl analogues of valproic acid amides in a rat model of neuropathic pain.
    Neuropharmacology, 2005, Volume: 49, Issue:8

    Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Male; Pain; Pain Measurement; Peripheral

2005
Apparent valproic acid neurotoxicity in a hypoalbuminemic patient.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:1

    Topics: Adult; Humans; Male; Peripheral Nervous System Diseases; Serum Albumin; Valproic Acid

1993
Nutritional depletion polyneuropathy and valproic acid.
    Archives of internal medicine, 1993, Apr-12, Volume: 153, Issue:7

    Topics: Aged; Humans; Male; Peripheral Nervous System Diseases; Thiamine Deficiency; Valproic Acid

1993
Chronic hiccups.
    American family physician, 1986, Volume: 34, Issue:5

    Topics: Adult; Anticonvulsants; Central Nervous System Diseases; Chronic Disease; Diabetes Complications; Fe

1986