valproic acid has been researched along with Penile Induration in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Penile Induration: A condition characterized by hardening of the PENIS due to the formation of fibrous plaques on the dorsolateral aspect of the PENIS, usually involving the membrane (tunica albuginea) surrounding the erectile tissue (corpus cavernosum penis). This may eventually cause a painful deformity of the shaft or constriction of the urethra, or both.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the therapeutic effects of valproic acid (VPA) on erectile dysfunction and reducing penile fibrosis in streptozocin (STZ)-induced diabetic rats." | 3.83 | Antifibrogenic role of valproic acid in streptozotocin induced diabetic rat penis. ( Bayraktar, C; Eren, H; Gurgen, SG; Karaguzel, E; Kazaz, IO; Kutlu, O; Kutlu, S; Okatan, AE, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hannan, JL | 1 |
| Kutlu, O | 2 |
| Stopak, BL | 1 |
| Liu, X | 1 |
| Castiglione, F | 1 |
| Hedlund, P | 1 |
| Burnett, AL | 1 |
| Bivalacqua, TJ | 1 |
| Karaguzel, E | 1 |
| Gurgen, SG | 1 |
| Okatan, AE | 1 |
| Kutlu, S | 1 |
| Bayraktar, C | 1 |
| Kazaz, IO | 1 |
| Eren, H | 1 |
2 other studies available for valproic acid and Penile Induration
| Article | Year |
|---|---|
Valproic acid prevents penile fibrosis and erectile dysfunction in cavernous nerve-injured rats.
Topics: Animals; Blotting, Western; Erectile Dysfunction; Fibrosis; Histone Deacetylase Inhibitors; Histone | 2014 |
Antifibrogenic role of valproic acid in streptozotocin induced diabetic rat penis.
Topics: Animals; Apoptosis; Diabetes Mellitus, Experimental; Erectile Dysfunction; Humans; Injections, Intra | 2016 |