Page last updated: 2024-10-26

valproic acid and Pancreatitis

valproic acid has been researched along with Pancreatitis in 98 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Pancreatitis: INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.

Research Excerpts

ExcerptRelevanceReference
"A 12-year-old boy developed pancreatitis, complicated by a pancreatic pseudocyst, as an adverse reaction to valproic acid (VPA) treatment for epilepsy."8.82Pancreatitis, complicated by a pancreatic pseudocyst associated with the use of valproic acid. ( Houben, ML; Stroink, H; van Dijken, PJ; Wilting, I, 2005)
"The author reports one case of pseudocyst of the pancreas, an uncommon disorder in children, secondary to pancreatitis in a 9-year-old girl treated with valproic acid for epilepsy."8.82Pancreatic pseudocyst caused by valproic acid: case report and review of the literature. ( Hernández, F; Queizán, A; Rivas, S, 2003)
"Valproic acid (VPA) is a commonly prescribed medication approved for use in the United States for epilepsy, migraine, and bipolar disorder."8.82Acute pancreatitis in children from Valproic acid: case series and review. ( Feldman-Winter, LB; Goldfarb, O; Grauso-Eby, NL; McAbee, GN, 2003)
"Acute pancreatitis is a rare, albeit severe, secondary effect of valproic acid which is probably due to an idiosyncratic reaction."8.79[Acute pancreatitis caused by valproic acid: apropos a case]. ( Bahamonde Carrasco, A; Morán Blanco, A; Olcoz Goñi, JL, 1996)
"We describe a case of a 31-year-old woman with cerebral palsy who developed fatal acute hemorrhagic pancreatitis while being treated with valproic acid to control her seizure activity."8.79Fatal acute pancreatitis caused by valproic acid. ( Evans, RJ; Jordan, J; Krolikowski, FJ; Miranda, RN, 1995)
"We describe three patients with seizure disorders in whom pancreatitis or pancreatic injury was probably caused by valproic acid, a widely used anticonvulsant drug."8.78Valproic acid-associated pancreatitis: report of three cases and a brief review. ( Bobo, RC; Bond, LW; Lott, JA; McClung, HJ; Murray, RD, 1990)
"An 11 year-old epileptic boy, treated with valproic acid developed after 11 months on therapy a severe acute pancreatitis."8.78[Acute pancreatitis and valproic acid]. ( Bovier Lapierre, M; Jalaguier, E; Kayemba Kay's Kabangu, S, 1991)
"We reported a case of acute pancreatitis occurring during administration of valproic acid for epilepsy."8.78[A case of acute pancreatitis during administration of valproic acid]. ( Ito, S; Kobayashi, K; Kuniya, T; Mimasu, S; Momota, T, 1993)
"Valproic acid (VPA) is a relatively safe drug widely used for the treatment of epileptic seizures and mania in bipolar disorder, as well as the prevention of migraine headaches."8.31Acute pancreatitis during valproic acid administration in a patient with vascular dementia, epileptic seizures, and psychiatric symptoms: a case report. ( Harada, M; Hashimoto, R; Igata, R; Ikenouchi, A; Isomoto, N; Konishi, Y; Okamoto, N; Shinkai, T; Yanaga, M; Yoshimura, R, 2023)
"Drug-induced acute pancreatitis is a rare condition in childhood, and information about the incidence of valproic acid-induced acute pancreatitis in the pediatric population is scarce."7.79Valproic acid-induced pancreatitis in a 15-year-old boy with juvenile myoclonic epilepsy. ( Talvik, I; Talvik, T; Uibo, O; Veri, K, 2013)
"Valproic acid-associated pancreatitis does not depend on valproic acid serum level and may occur any time after the onset of therapy."7.73The spectrum of valproic acid-associated pancreatitis. ( Fish, DL; Werlin, SL, 2006)
"A nondiabetic young male patient in hypomanic phase of bipolar disorder on maintenance treatment with sodium valproate, developed transient episode of acute pancreatitis and diabetic ketoacidosis after addition of chlorpromazine and halopridol."7.72Acute pancreatitis and diabetic ketoacidosis in non-diabetic person while on treatment with sodium valproate, chlorpromazine and haloperidol. ( Gupta, SB; Laghate, VD, 2004)
"In the past 6 years, 11 children on valproic acid have developed pancreatitis in our children's hospital."7.72Valproic acid-induced pancreatitis in childhood epilepsy: case series and review. ( Berg, M; Breault, R; Sinclair, DB, 2004)
"A 14-year-old child treated with valproic acid over several years for a seizure disorder developed abdominal pain with radiological evidence of acute pancreatitis."7.71A case of chronic pancreatic insufficiency due to valproic acid in a child. ( Cooper, MA; Groll, A, 2001)
"Four children treated with maintenance dialysis, three peritoneal and one hemodialysis, developed pancreatitis while receiving valproic acid (VPA) for chronic seizure disorders."7.68Pancreatitis in children on chronic dialysis treated with valproic acid. ( Ford, DM; Lum, GM; Portman, RJ, 1990)
"Four patients had pancreatitis associated with valproic acid therapy."7.67Pancreatitis associated with valproic acid therapy. ( Cruse, RP; Erenberg, G; Rothner, AD; Wyllie, E; Wyllie, R, 1984)
"The development of acute pancreatitis in an 8-year-old boy being treated with valproic acid for simple absence spells is documented."7.66Pancreatitis associated with valproic acid therapy. ( Batalden, PB; Cloyd, J; Van Dyne, BJ, 1979)
"Acute pancreatitis is rarely seen in children, and, in contrast to cases in adults, it is often drug induced."6.44Valproic acid-induced pancreatitis: 16 new cases and a review of the literature. ( Bell, N; Bettendorf, U; Brockmann, K; Büsing, D; Eckel, U; Gerstner, T; Hanefeld, F; Hebing, B; Hoffmann, R; Kasper, JM; Klostermann, W; König, S; Longin, E; Neumann, FW; Sandrieser, T; Weidner, B; Wiemer-Kruel, A; Wolff, M, 2007)
"Valproic acid (VPA) has been widely used more frequently as its approved indications have been expanded."5.62Rhabdomyolysis and Hepatotoxicity From Valproic Acid: Case Reports. ( Deb, S; Walker, CP, 2021)
"A definite cause of pancreatitis is due to the antiepileptic drug valproic acid (VPA)."5.42Valproic Acid Limits Pancreatic Recovery after Pancreatitis by Inhibiting Histone Deacetylases and Preventing Acinar Redifferentiation Programs. ( Criscimanna, A; Davis, AW; Dionise, ZR; Eisses, JF; Esni, F; Husain, SZ; Javed, TA; Jin, S; Lowe, ME; Monga, SP; Orabi, AI; Ozolek, JA; Poddar, M; Rohde, GK; Sarwar, S; Singh, S; Tosun, AB; Zhou, L, 2015)
"Acute pancreatitis is rarely seen in children, and it is often drug induced."5.35Acute hemorrhagic pancreatitis due to the use of valproic acid in a child. ( Köse, G; Ozaydin, E; Yükselgüngör, H, 2008)
"A 12-year-old boy developed pancreatitis, complicated by a pancreatic pseudocyst, as an adverse reaction to valproic acid (VPA) treatment for epilepsy."4.82Pancreatitis, complicated by a pancreatic pseudocyst associated with the use of valproic acid. ( Houben, ML; Stroink, H; van Dijken, PJ; Wilting, I, 2005)
"The author reports one case of pseudocyst of the pancreas, an uncommon disorder in children, secondary to pancreatitis in a 9-year-old girl treated with valproic acid for epilepsy."4.82Pancreatic pseudocyst caused by valproic acid: case report and review of the literature. ( Hernández, F; Queizán, A; Rivas, S, 2003)
"Valproic acid (VPA) is a commonly prescribed medication approved for use in the United States for epilepsy, migraine, and bipolar disorder."4.82Acute pancreatitis in children from Valproic acid: case series and review. ( Feldman-Winter, LB; Goldfarb, O; Grauso-Eby, NL; McAbee, GN, 2003)
"We describe a case of a 31-year-old woman with cerebral palsy who developed fatal acute hemorrhagic pancreatitis while being treated with valproic acid to control her seizure activity."4.79Fatal acute pancreatitis caused by valproic acid. ( Evans, RJ; Jordan, J; Krolikowski, FJ; Miranda, RN, 1995)
"Acute pancreatitis is a rare, albeit severe, secondary effect of valproic acid which is probably due to an idiosyncratic reaction."4.79[Acute pancreatitis caused by valproic acid: apropos a case]. ( Bahamonde Carrasco, A; Morán Blanco, A; Olcoz Goñi, JL, 1996)
"We reported a case of acute pancreatitis occurring during administration of valproic acid for epilepsy."4.78[A case of acute pancreatitis during administration of valproic acid]. ( Ito, S; Kobayashi, K; Kuniya, T; Mimasu, S; Momota, T, 1993)
"We report a case of pancreatitis with fatal liver failure, in a 21-year-old, mentally retarded patient, taking valproic acid (VPA) therapy, together with a review of the literature of this rare side effect."4.78Valproic-acid-induced pancreatitis. Case report and review of the literature. ( Binek, J; Hany, A; Heer, M, 1991)
"We describe three patients with seizure disorders in whom pancreatitis or pancreatic injury was probably caused by valproic acid, a widely used anticonvulsant drug."4.78Valproic acid-associated pancreatitis: report of three cases and a brief review. ( Bobo, RC; Bond, LW; Lott, JA; McClung, HJ; Murray, RD, 1990)
"An 11 year-old epileptic boy, treated with valproic acid developed after 11 months on therapy a severe acute pancreatitis."4.78[Acute pancreatitis and valproic acid]. ( Bovier Lapierre, M; Jalaguier, E; Kayemba Kay's Kabangu, S, 1991)
"Valproic acid (VPA) is a relatively safe drug widely used for the treatment of epileptic seizures and mania in bipolar disorder, as well as the prevention of migraine headaches."4.31Acute pancreatitis during valproic acid administration in a patient with vascular dementia, epileptic seizures, and psychiatric symptoms: a case report. ( Harada, M; Hashimoto, R; Igata, R; Ikenouchi, A; Isomoto, N; Konishi, Y; Okamoto, N; Shinkai, T; Yanaga, M; Yoshimura, R, 2023)
"Drug-induced acute pancreatitis is a rare condition in childhood, and information about the incidence of valproic acid-induced acute pancreatitis in the pediatric population is scarce."3.79Valproic acid-induced pancreatitis in a 15-year-old boy with juvenile myoclonic epilepsy. ( Talvik, I; Talvik, T; Uibo, O; Veri, K, 2013)
"5 years old male with myoclonic epilepsy on Valproic acid (VPA) monotherapy, developed an acute pancreatitis."3.77VPA-induced recurrent pancreatitis in a cystic fibrosis carrier. ( Alexopoulou, E; Attilakos, A; Dinopoulos, A; Fretzayas, A; Karapanou, O; Tzetis, M, 2011)
"Our study underscores the importance of considering drugs as a cause and a contributor to pancreatitis in children, particularly valproic acid in young children."3.77Novel characterization of drug-associated pancreatitis in children. ( Bai, HX; Bhandari, V; Husain, SZ; Latif, SU; Ma, MH; Orabi, AI; Park, A, 2011)
"Valproic acid-associated pancreatitis does not depend on valproic acid serum level and may occur any time after the onset of therapy."3.73The spectrum of valproic acid-associated pancreatitis. ( Fish, DL; Werlin, SL, 2006)
" The example of pancreatitis risk with atypical antipsychotics, valproic acid, and valproate is used to discuss the strengths and limitations of MGPS versus traditional methods."3.72Pharmacovigilance in the 21st century: new systematic tools for an old problem. ( Doraiswamy, PM; Szarfman, A; Tonning, JM, 2004)
"A nondiabetic young male patient in hypomanic phase of bipolar disorder on maintenance treatment with sodium valproate, developed transient episode of acute pancreatitis and diabetic ketoacidosis after addition of chlorpromazine and halopridol."3.72Acute pancreatitis and diabetic ketoacidosis in non-diabetic person while on treatment with sodium valproate, chlorpromazine and haloperidol. ( Gupta, SB; Laghate, VD, 2004)
"In the past 6 years, 11 children on valproic acid have developed pancreatitis in our children's hospital."3.72Valproic acid-induced pancreatitis in childhood epilepsy: case series and review. ( Berg, M; Breault, R; Sinclair, DB, 2004)
"A 14-year-old child treated with valproic acid over several years for a seizure disorder developed abdominal pain with radiological evidence of acute pancreatitis."3.71A case of chronic pancreatic insufficiency due to valproic acid in a child. ( Cooper, MA; Groll, A, 2001)
"Pancreatitis is a serious adverse effect of valproic acid (VPA)."3.70On the toxicity of valproic-acid. ( Alonso, R; Cuiña, L; Moreiras Plaza, M; Rodríguez Goyanes, G, 1999)
"An 11-year-old girl with juvenile neuronal ceroid lipofuscinosis developed acute pancreatitis secondary to valproic acid treatment, which resolved after discontinuation of the medication and conservative treatment."3.69Valproate-associated acute pancreatitis in a child with neuronal ceroid lipofuscinosis. ( Talwar, D, 1994)
"We report the case of a young man suffering from epilepsy who developed chronic calcified pancreatitis after ten years of therapy with the anticonvulsant drugs carbamazepine and phenytoin."3.68Anticonvulsant-induced chronic pancreatitis. A case report. ( Billi, P; Broccoli, PL; Fontana, G; Melandri, R; Pezzilli, R, 1992)
"Four children treated with maintenance dialysis, three peritoneal and one hemodialysis, developed pancreatitis while receiving valproic acid (VPA) for chronic seizure disorders."3.68Pancreatitis in children on chronic dialysis treated with valproic acid. ( Ford, DM; Lum, GM; Portman, RJ, 1990)
"Four patients had pancreatitis associated with valproic acid therapy."3.67Pancreatitis associated with valproic acid therapy. ( Cruse, RP; Erenberg, G; Rothner, AD; Wyllie, E; Wyllie, R, 1984)
"The development of acute pancreatitis in an 8-year-old boy being treated with valproic acid for simple absence spells is documented."3.66Pancreatitis associated with valproic acid therapy. ( Batalden, PB; Cloyd, J; Van Dyne, BJ, 1979)
"Acute pancreatitis is rarely seen in children, and, in contrast to cases in adults, it is often drug induced."2.44Valproic acid-induced pancreatitis: 16 new cases and a review of the literature. ( Bell, N; Bettendorf, U; Brockmann, K; Büsing, D; Eckel, U; Gerstner, T; Hanefeld, F; Hebing, B; Hoffmann, R; Kasper, JM; Klostermann, W; König, S; Longin, E; Neumann, FW; Sandrieser, T; Weidner, B; Wiemer-Kruel, A; Wolff, M, 2007)
"5 and year-old epileptic boy with severe acute pancreatitis which appeared 39 months after starting treatment with sodium valproate (VAP) at a daily dosage of 26."2.38[Acute pancreatitis caused by sodium valproate. Review of the literature apropos of a case in a child]. ( Boussard, N; de Miscault, G; Rose, E; Thome, M, 1991)
"A case of valproate induced acute pancreatitis operated as surgical abdomen has been reported here."1.72Valproate Induced Acute Pancreatitis - A Unique Case Report. ( Chauhan, V; Garg, GK; Kapur, A; Sharma, M, 2022)
"Valproic acid (VPA) has been widely used more frequently as its approved indications have been expanded."1.62Rhabdomyolysis and Hepatotoxicity From Valproic Acid: Case Reports. ( Deb, S; Walker, CP, 2021)
"As rare as drug-induced acute pancreatitis can be, it should not be overlooked, Moreover, the mechanism of how sodium valproate induces acute pancreatitis remains unknown."1.51Sodium valproate induced acute pancreatitis in a bipolar disorder patient: a case report. ( Huang, W; Ren, X; Shen, F; Xing, B, 2019)
"A definite cause of pancreatitis is due to the antiepileptic drug valproic acid (VPA)."1.42Valproic Acid Limits Pancreatic Recovery after Pancreatitis by Inhibiting Histone Deacetylases and Preventing Acinar Redifferentiation Programs. ( Criscimanna, A; Davis, AW; Dionise, ZR; Eisses, JF; Esni, F; Husain, SZ; Javed, TA; Jin, S; Lowe, ME; Monga, SP; Orabi, AI; Ozolek, JA; Poddar, M; Rohde, GK; Sarwar, S; Singh, S; Tosun, AB; Zhou, L, 2015)
"It has been reported that acute pancreatitis induced by VPA is caused by intermediate metabolites of VPA."1.40Development of acute pancreatitis caused by sodium valproate in a patient with bipolar disorder on hemodialysis for chronic renal failure: a case report. ( Okayasu, H; Osone, A; Ozeki, Y; Shimoda, K; Shinozaki, T, 2014)
"PFTS inhibited the growth of human pancreatic cancer cells in culture in a concentration- and time-dependent manner."1.39A novel Ras inhibitor (MDC-1016) reduces human pancreatic tumor growth in mice. ( Alston, N; Bartels, LE; Mackenzie, GG; Ouyang, N; Papayannis, I; Rigas, B; Vrankova, K; Xie, G, 2013)
"Although the relationship between xanthomata, hypertriglyceridemia, and diabetes may be well known in adults, in children, xanthomata are very rarely the presenting feature of diabetes of any cause."1.38Xanthomata and diabetes in an adolescent with familial dysbetalipoproteinemia 9 yr after valproate-induced pancreatitis. ( Fiorillo, L; Jetha, MM, 2012)
"The proportion of drug-induced acute pancreatitis was 5."1.36Incidence, severity, and etiology of drug-induced acute pancreatitis. ( Procházka, M; Procházka, V; Urbánek, K; Vinklerová, I, 2010)
"Acute pancreatitis is rarely seen in children, and it is often drug induced."1.35Acute hemorrhagic pancreatitis due to the use of valproic acid in a child. ( Köse, G; Ozaydin, E; Yükselgüngör, H, 2008)
" Adverse events and reasons for terminating the diet were tabulated."1.33Safety and tolerability of the ketogenic diet in pediatric epilepsy: effects of valproate combination therapy. ( Ghosh, S; Lyczkowski, DA; Pfeifer, HH; Thiele, EA, 2005)
"Post-ERCP pancreatitis was defined as abdominal pain and/or vomiting associated with amylase/lipase plasma levels equal to or greater than twice the upper normal value."1.32Are drugs a risk factor of post-ERCP pancreatitis? ( Bauret, P; Berthier, E; Blanc, F; Blayac, JP; Fabbro-Peray, P; Hanslik, B; Hillaire-Buys, D; Larrey, D; Melki, M; Pageaux, GP; Perney, P; Roques, V, 2003)
"Pancreatitis is more common in children than previously thought."1.32Pancreatitis in children. ( Frautschy, BC; Kugathasan, S; Werlin, SL, 2003)
"An acute pancreatitis is relatively common after intravenous administration."1.32[An acute pancreatitis in a child caused by Na-valproate]. ( Jeremić, Lj; Jovanović, M; Karadzić, D; Madić, J; Stanojević, G; Stojanović, M; Zivanović, D, 2004)
"Acute pancreatitis has been associated with a number of medications, including valproate (VPA)."1.31Acute pancreatitis coincident with valproate use: a critical review. ( Deaton, R; Pellock, JM; Sommerville, KW; Wilder, BJ, 2002)
"Valproic acid is an effective antiseizure medication that is also used for other indications such as migraine prophylaxis."1.30Multiorgan system failure caused by valproic acid toxicity. ( Pinkston, R; Walker, LA, 1997)
"The patients were comatose for 6 and 7 days and required mechanical ventilation for 7 and 10 days."1.29Life threatening intoxication with sodium valproate. ( Andersen, GO; Ritland, S, 1995)
"We report a fatal case of haemorrhagic pancreatic necrosis in a 15-year-old mentally retarded epileptic male who had been taking sodium valproate (VPA) in the recommended dosage for one and a half years."1.29[Fatal pancreatitis associated with valproate therapy]. ( Engelmann, MD; Henriksen, SD; Tingsgaard, LK, 1995)
"Pancreatitis is usually considered a rare side effect of valproate."1.29Valproate-associated pancreatitis and cholecystitis in six mentally retarded adults. ( Buzan, RD; Dubovsky, SL; Firestone, D; Thomas, M, 1995)
"Valproic acid is a reliable and comparatively safe drug in the treatment of special forms of absence seizures."1.27[Unapparent course of pancreatitis with pseudocyst development and cholestatic jaundice in anticonvulsive therapy with valproate]. ( Braun, E; Bundschu, HD; Spannagel, B, 1987)

Research

Studies (98)

TimeframeStudies, this research(%)All Research%
pre-199023 (23.47)18.7374
1990's24 (24.49)18.2507
2000's31 (31.63)29.6817
2010's15 (15.31)24.3611
2020's5 (5.10)2.80

Authors

AuthorsStudies
Chauhan, V1
Sharma, M1
Kapur, A1
Garg, GK1
Wartman, C1
VandenBerg, A1
Yanaga, M1
Okamoto, N1
Hashimoto, R1
Igata, R1
Konishi, Y1
Ikenouchi, A1
Isomoto, N1
Shinkai, T1
Harada, M1
Yoshimura, R1
Walker, CP1
Deb, S1
Huang, W1
Ren, X1
Shen, F1
Xing, B1
Finsterer, J1
Quan, W1
Shao, Q1
Zhang, H1
Liu, FH1
Zhang, XH1
Gupta, J1
Sinha, R1
Jauhari, P1
Malik, R1
Chakrabarty, B1
Gulati, S1
Yaman, A1
Kendirli, T1
Odek, C1
Bektaş, O1
Kuloğlu, Z1
Koloğlu, M1
Ince, E1
Deda, G1
Mackenzie, GG1
Bartels, LE1
Xie, G1
Papayannis, I1
Alston, N1
Vrankova, K1
Ouyang, N1
Rigas, B1
Okayasu, H1
Shinozaki, T1
Osone, A1
Ozeki, Y1
Shimoda, K1
Veri, K1
Uibo, O1
Talvik, I1
Talvik, T1
Eisses, JF1
Criscimanna, A1
Dionise, ZR1
Orabi, AI2
Javed, TA1
Sarwar, S1
Jin, S1
Zhou, L1
Singh, S1
Poddar, M1
Davis, AW1
Tosun, AB1
Ozolek, JA1
Lowe, ME1
Monga, SP1
Rohde, GK1
Esni, F1
Husain, SZ2
Kanofsky, JD1
Woesner, ME1
Guevara-Campos, J1
González-Guevara, L1
Vacaro-Bolívar, I1
Rojas, JM1
Santos, BL1
Fernandes, RM1
Neves, FF1
Vinklerová, I1
Procházka, M1
Procházka, V1
Urbánek, K1
Kwan, SY1
Bai, HX1
Ma, MH1
Park, A1
Latif, SU1
Bhandari, V1
Dinopoulos, A1
Karapanou, O1
Alexopoulou, E1
Tzetis, M1
Attilakos, A1
Fretzayas, A1
Jetha, MM1
Fiorillo, L1
Jakobović, J1
Butković, D1
Popović, L1
Skarić, I1
Mikecin, L1
Yazdani, K1
Lippmann, M1
Gala, I1
Pellock, JM1
Wilder, BJ1
Deaton, R1
Sommerville, KW1
Queizán, A1
Hernández, F1
Rivas, S1
Grauso-Eby, NL1
Goldfarb, O1
Feldman-Winter, LB1
McAbee, GN1
Gonzalez-Heydrich, J1
Raches, D1
Wilens, TE1
Leichtner, A1
Mezzacappa, E1
Werlin, SL2
Kugathasan, S1
Frautschy, BC1
Perney, P1
Berthier, E1
Pageaux, GP1
Hillaire-Buys, D1
Roques, V1
Fabbro-Peray, P1
Melki, M1
Hanslik, B1
Bauret, P1
Larrey, D1
Blayac, JP1
Blanc, F1
Yoshikawa, H1
Szarfman, A1
Tonning, JM1
Doraiswamy, PM1
Sinclair, DB1
Berg, M1
Breault, R1
Laghate, VD1
Gupta, SB1
Houben, ML1
Wilting, I1
Stroink, H1
van Dijken, PJ1
Eyer, F1
Felgenhauer, N1
Gempel, K1
Steimer, W1
Gerbitz, KD1
Zilker, T1
Stojanović, M2
Zivanović, D1
Madić, J1
Karadzić, D1
Stanojević, G1
Jovanović, M1
Jeremić, Lj1
Lyczkowski, DA1
Pfeifer, HH1
Ghosh, S1
Thiele, EA1
Phillips, RA1
Nadel, ES1
Brown, DF1
Fish, DL1
Gerstner, T3
Büsing, D1
Bell, N3
Longin, E2
Kasper, JM1
Klostermann, W1
Hebing, B1
Hanefeld, F1
Eckel, U1
Hoffmann, R1
Bettendorf, U1
Weidner, B1
Wiemer-Kruel, A1
Brockmann, K1
Neumann, FW1
Sandrieser, T1
Wolff, M1
König, S2
Zaccara, G1
Franciotta, D1
Perucca, E1
Bauer, MO1
Koenig, SA1
Ben Salem, C1
Biour, M1
Hmouda, H1
Bouraoui, A1
Ozaydin, E1
Yükselgüngör, H1
Köse, G1
Kozu, T1
Sasaki, M1
Tonoda, S1
Aoki, Y1
Katsumi, M1
Murphy, MJ1
Lyon, IW1
Taylor, JW1
Mitts, G1
Mangini, RJ1
Parker, PH1
Helinek, GL1
Ghishan, FK1
Greene, HL1
Bale, JF1
Gay, PE1
Madsen, JA1
Torelli, D2
Galeone, D2
Lamontanara, G2
Wyllie, E1
Wyllie, R1
Cruse, RP1
Erenberg, G1
Rothner, AD1
Williams, LH1
Reynolds, RP1
Emery, JL1
Isom, JB1
Coulter, DL2
Allen, RJ3
Lankisch, PG1
Criée, CP1
Ng, JY1
Disney, AP1
Jones, TE1
Purdie, G1
Callaghan, N1
O'Hare, J1
O'Driscoll, D1
O'Neill, B1
Daly, M1
Tobias, JD1
Capers, C1
Sims, P1
Holcomb, GW1
Buzan, RD1
Firestone, D1
Thomas, M1
Dubovsky, SL1
Engelmann, MD1
Henriksen, SD1
Tingsgaard, LK1
Werth, B1
Kuhn, M1
Hartmann, K1
Reinhart, WH1
Andersen, GO1
Ritland, S1
Evans, RJ1
Miranda, RN1
Jordan, J1
Krolikowski, FJ1
Croizet, O1
Louvel, D1
Teulière, JP1
Buscail, L1
Escourrou, J1
Frexinos, J1
Talwar, D1
Momota, T1
Ito, S1
Kobayashi, K1
Mimasu, S1
Kuniya, T1
Bahamonde Carrasco, A1
Morán Blanco, A1
Olcoz Goñi, JL1
Riikonen, R1
Levin, TL1
Berdon, WE1
Seigle, RR1
Nash, MA1
Pinkston, R1
Walker, LA1
Moreiras Plaza, M1
Rodríguez Goyanes, G1
Cuiña, L1
Alonso, R1
Fecik, SE1
Stoner, SC1
Raphael, J1
Lindsey, C1
Cooper, MA1
Groll, A1
Munhoz, RP1
dos Santos, ML1
Hernández-Fustes, OJ1
Chapman, SA1
Wacksman, GP1
Patterson, BD1
Taira, N1
Nishi, H1
Mano, M1
Waki, N1
Tsugita, Y1
Takashima, S1
Fukuda, K1
Komatsubara, S1
Grosse, P1
Rüsch, L1
Schmitz, B1
Camfield, PR1
Bagnell, P1
Camfield, CS1
Tibbles, JA1
Batalden, PB1
Van Dyne, BJ1
Cloyd, J1
Ozawa, Y1
Inagaki, Y1
Yonei, Y1
Tsukada, N1
Okawa, H1
Kiryu, Y1
Oda, M1
Pezzilli, R1
Billi, P1
Melandri, R1
Broccoli, PL1
Fontana, G1
Kayemba Kay's Kabangu, S1
Bovier Lapierre, M1
Jalaguier, E1
Rose, E1
de Miscault, G1
Thome, M1
Boussard, N1
Binek, J1
Hany, A1
Heer, M1
Lott, JA1
Bond, LW1
Bobo, RC1
McClung, HJ1
Murray, RD1
Walker, RM1
Smith, GS1
Barsoum, NJ1
Macallum, GE1
Ford, DM1
Portman, RJ1
Lum, GM1
Bouget, J1
Deugnier, Y1
Camus, C1
Thoreux, PH1
Letulzo, Y1
Thomas, R1
Ramée, MP1
Gram, L1
Bentsen, KD1
Dobrilla, G2
Felder, M2
Chilovi, F2
Rosenberg, HK1
Ortega, W1
Braun, E1
Spannagel, B1
Bundschu, HD1

Reviews

20 reviews available for valproic acid and Pancreatitis

ArticleYear
Valproate: Not All Boxed Warnings Are Created Equal.
    The Annals of pharmacotherapy, 2022, Volume: 56, Issue:12

    Topics: Anticonvulsants; Chemical and Drug Induced Liver Injury; Drug Labeling; Drug-Related Side Effects an

2022
Valproic acid-induced acute pancreatitis and multiorgan failure in a child.
    Pediatric emergency care, 2013, Volume: 29, Issue:5

    Topics: Abdominal Pain; Acute Disease; Anticonvulsants; Child; Delayed Diagnosis; Diagnostic Errors; Dissemi

2013
Fatal pancreatitis associated with valproic acid: review of the literature.
    Medicine, 2002, Volume: 81, Issue:4

    Topics: Fatal Outcome; Humans; Male; Middle Aged; Pancreatitis; Valproic Acid

2002
Pancreatic pseudocyst caused by valproic acid: case report and review of the literature.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 2003, Volume: 13, Issue:1

    Topics: Amylases; Anticonvulsants; Child; Epilepsy; Female; Humans; Pancreatic Pseudocyst; Pancreatitis; Val

2003
Acute pancreatitis in children from Valproic acid: case series and review.
    Pediatric neurology, 2003, Volume: 28, Issue:2

    Topics: Acute Disease; Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Fatal Outcome; Female

2003
Pancreatitis, complicated by a pancreatic pseudocyst associated with the use of valproic acid.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2005, Volume: 9, Issue:2

    Topics: Acute Disease; Anticonvulsants; Child; Epilepsy; Humans; Male; Pancreatic Pseudocyst; Pancreatitis;

2005
Valproic acid-induced pancreatitis: 16 new cases and a review of the literature.
    Journal of gastroenterology, 2007, Volume: 42, Issue:1

    Topics: Amylases; Anticonvulsants; Child; Germany; Health Surveys; Humans; Lipase; Pancreatitis; Severity of

2007
Idiosyncratic adverse reactions to antiepileptic drugs.
    Epilepsia, 2007, Volume: 48, Issue:7

    Topics: Age Factors; Anemia, Aplastic; Anticonvulsants; B-Lymphocytes; Central Nervous System Diseases; Chem

2007
[Drug-induced pancreatitis].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Azathioprine;

2007
Oral valproic acid for epilepsy--long-term experience in therapy and side effects.
    Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:2

    Topics: Administration, Oral; Animals; Anticonvulsants; Epilepsy; Gastrointestinal Diseases; Humans; Pancrea

2008
Fatal acute pancreatitis caused by valproic acid.
    The American journal of forensic medicine and pathology, 1995, Volume: 16, Issue:1

    Topics: Acute Disease; Adult; Cerebral Palsy; Fatal Outcome; Female; Humans; Pancreatitis; Seizures; Valproi

1995
[A case of acute pancreatitis during administration of valproic acid].
    No to hattatsu = Brain and development, 1993, Volume: 25, Issue:5

    Topics: Acute Disease; Adolescent; Epilepsy; Humans; Male; Pancreatitis; Valproic Acid

1993
[Acute pancreatitis caused by valproic acid: apropos a case].
    Gastroenterologia y hepatologia, 1996, Volume: 19, Issue:5

    Topics: Acute Disease; Adolescent; Anticonvulsants; Drug Therapy, Combination; Humans; Male; Pancreatitis; V

1996
Pancreatitis associated with valproic acid: a review of the literature.
    Pharmacotherapy, 2001, Volume: 21, Issue:12

    Topics: Amylases; Anticonvulsants; Humans; Pancreatitis; Valproic Acid

2001
Pancreatitis induced by valproic acid: report of a case.
    Surgery today, 2001, Volume: 31, Issue:11

    Topics: Adult; Anticonvulsants; Cholangiopancreatography, Endoscopic Retrograde; Chronic Disease; Female; Fi

2001
[Acute pancreatitis and valproic acid].
    Pediatrie, 1991, Volume: 46, Issue:12

    Topics: Acute Disease; Child; Epilepsy; Humans; Male; Pancreatitis; Valproic Acid

1991
[Acute pancreatitis caused by sodium valproate. Review of the literature apropos of a case in a child].
    Pediatrie, 1991, Volume: 46, Issue:12

    Topics: Acute Disease; Child; Humans; Male; Pancreatitis; Prognosis; Valproic Acid

1991
Valproic-acid-induced pancreatitis. Case report and review of the literature.
    Journal of clinical gastroenterology, 1991, Volume: 13, Issue:6

    Topics: Adult; Chemical and Drug Induced Liver Injury; Humans; Male; Pancreatitis; Valproic Acid

1991
Valproic acid-associated pancreatitis: report of three cases and a brief review.
    Clinical chemistry, 1990, Volume: 36, Issue:2

    Topics: Adolescent; Child, Preschool; Female; Humans; Pancreatitis; Valproic Acid

1990
Valproate: an updated review.
    Acta neurologica Scandinavica, 1985, Volume: 72, Issue:2

    Topics: Abnormalities, Drug-Induced; Brain Diseases; Chemical and Drug Induced Liver Injury; Coma; Dyskinesi

1985

Trials

1 trial available for valproic acid and Pancreatitis

ArticleYear
Comparative study of ethosuximide and sodium valproate in the treatment of typical absence seizures (petit mal).
    Developmental medicine and child neurology, 1982, Volume: 24, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Epilepsy, Absen

1982

Other Studies

77 other studies available for valproic acid and Pancreatitis

ArticleYear
Valproate Induced Acute Pancreatitis - A Unique Case Report.
    Current drug safety, 2022, Volume: 17, Issue:4

    Topics: Acute Disease; Adolescent; Child; Humans; Pancreatitis; Seizures; Valproic Acid

2022
Acute pancreatitis during valproic acid administration in a patient with vascular dementia, epileptic seizures, and psychiatric symptoms: a case report.
    Journal of medical case reports, 2023, May-29, Volume: 17, Issue:1

    Topics: Acute Disease; Aged; Amylases; Anticonvulsants; Dementia, Vascular; Epilepsy; Humans; Male; Pancreat

2023
Rhabdomyolysis and Hepatotoxicity From Valproic Acid: Case Reports.
    Journal of pharmacy practice, 2021, Volume: 34, Issue:4

    Topics: Adult; Anticonvulsants; Blood Coagulation Disorders; Chemical and Drug Induced Liver Injury; Female;

2021
Sodium valproate induced acute pancreatitis in a bipolar disorder patient: a case report.
    BMC pharmacology & toxicology, 2019, 11-29, Volume: 20, Issue:1

    Topics: Amylases; Antimanic Agents; Bipolar Disorder; Humans; Male; Middle Aged; Pancreatitis; Treatment Out

2019
Valproic acid for myoclonic epilepsy in POLG1 carriers can be fatal.
    Folia neuropathologica, 2021, Volume: 59, Issue:1

    Topics: Acute Disease; Anticonvulsants; Child; Diffuse Cerebral Sclerosis of Schilder; DNA Polymerase gamma;

2021
Acute Pancreatitis Associated with Valproate Treatment.
    Chinese medical journal, 2018, Aug-05, Volume: 131, Issue:15

    Topics: Acute Disease; Antimanic Agents; Chronic Disease; Humans; Pancreatitis; Valproic Acid

2018
Acute Severe Pancreatitis: A Dreadful Complication of Sodium Valproate.
    Indian journal of pediatrics, 2019, Volume: 86, Issue:7

    Topics: Abdominal Pain; Acute Disease; Child; Fever; Humans; Male; Pancreatitis; Tachypnea; Valproic Acid

2019
A novel Ras inhibitor (MDC-1016) reduces human pancreatic tumor growth in mice.
    Neoplasia (New York, N.Y.), 2013, Volume: 15, Issue:10

    Topics: Animals; Antineoplastic Agents; Benzoates; Cell Line, Tumor; Drug Synergism; Female; Heterografts; H

2013
Development of acute pancreatitis caused by sodium valproate in a patient with bipolar disorder on hemodialysis for chronic renal failure: a case report.
    BMC psychiatry, 2014, Mar-29, Volume: 14

    Topics: Abdominal Pain; Acute Disease; Anticonvulsants; Bipolar Disorder; Humans; Japan; Kidney Failure, Chr

2014
Valproic acid-induced pancreatitis in a 15-year-old boy with juvenile myoclonic epilepsy.
    Medicina (Kaunas, Lithuania), 2013, Volume: 49, Issue:11

    Topics: Acute Disease; Adolescent; Anticonvulsants; Estonia; Humans; Male; Myoclonic Epilepsy, Juvenile; Pan

2013
Valproic Acid Limits Pancreatic Recovery after Pancreatitis by Inhibiting Histone Deacetylases and Preventing Acinar Redifferentiation Programs.
    The American journal of pathology, 2015, Volume: 185, Issue:12

    Topics: Acinar Cells; Animals; Anticonvulsants; Cell Differentiation; Cell Proliferation; Ceruletide; Histon

2015
Clozapine-Valproate Adverse Drug Reactions and the Need for a Clozapine Rechallenge Case File.
    The primary care companion for CNS disorders, 2017, Jan-05, Volume: 19, Issue:1

    Topics: Acute Kidney Injury; Antimanic Agents; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; H

2017
Acute pancreatitis associated to the use of valproic acid.
    Arquivos de neuro-psiquiatria, 2009, Volume: 67, Issue:2B

    Topics: Acute Disease; Child; Epilepsy; Female; Humans; Pancreatitis; Valproic Acid

2009
Valproic acid-induced pancreatitis in an adult.
    Arquivos de neuro-psiquiatria, 2010, Volume: 68, Issue:1

    Topics: Adult; Anticonvulsants; Epilepsy; Humans; Male; Pancreatitis; Valproic Acid

2010
Incidence, severity, and etiology of drug-induced acute pancreatitis.
    Digestive diseases and sciences, 2010, Volume: 55, Issue:10

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Child; Child, Preschool; Cr

2010
The role of intravenous valproate in convulsive status epilepticus in the future.
    Acta neurologica Taiwanica, 2010, Volume: 19, Issue:2

    Topics: Anticonvulsants; Humans; Injections, Intravenous; Liver; Pancreatitis; Phenytoin; Practice Guideline

2010
Novel characterization of drug-associated pancreatitis in children.
    Journal of pediatric gastroenterology and nutrition, 2011, Volume: 53, Issue:4

    Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Child; Child, Preschool; Comorbidity; Crohn Dise

2011
VPA-induced recurrent pancreatitis in a cystic fibrosis carrier.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2011, Volume: 15, Issue:5

    Topics: Anticonvulsants; Child, Preschool; Cystic Fibrosis; Epilepsies, Myoclonic; Genetic Carrier Screening

2011
Xanthomata and diabetes in an adolescent with familial dysbetalipoproteinemia 9 yr after valproate-induced pancreatitis.
    Pediatric diabetes, 2012, Volume: 13, Issue:5

    Topics: Adolescent; Child, Preschool; Diabetes Complications; Female; Humans; Hyperlipoproteinemia Type III;

2012
[Acute childhood pancreatitis caused by valproate].
    Lijecnicki vjesnik, 2009, Volume: 131 Suppl 3

    Topics: Acute Disease; Adolescent; Anticonvulsants; Female; Humans; Pancreatitis; Valproic Acid

2009
Acute pancreatitis coincident with valproate use: a critical review.
    Epilepsia, 2002, Volume: 43, Issue:11

    Topics: Acute Disease; Adolescent; Adult; Amylases; Anticonvulsants; Child; Child, Preschool; Controlled Cli

2002
Retrospective study of hepatic enzyme elevations in children treated with olanzapine, divalproex, and their combination.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2003, Volume: 42, Issue:10

    Topics: Adolescent; Alanine Transaminase; Antimanic Agents; Antipsychotic Agents; Aspartate Aminotransferase

2003
Pancreatitis in children.
    Journal of pediatric gastroenterology and nutrition, 2003, Volume: 37, Issue:5

    Topics: Abdominal Pain; Adolescent; Amylases; Biliary Tract Diseases; Child; Child, Preschool; Hospitals, Pe

2003
Are drugs a risk factor of post-ERCP pancreatitis?
    Gastrointestinal endoscopy, 2003, Volume: 58, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Cholangiopancreatography, Endoscopic Retro

2003
The difficulties of diagnosing VPA-induced pancreatitis in children with severe motor and intellectual disabilities.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2004, Volume: 8, Issue:2

    Topics: Acute Disease; Anticonvulsants; Child, Preschool; Epilepsy; Female; Humans; Intellectual Disability;

2004
Pharmacovigilance in the 21st century: new systematic tools for an old problem.
    Pharmacotherapy, 2004, Volume: 24, Issue:9

    Topics: Adverse Drug Reaction Reporting Systems; Antipsychotic Agents; Humans; Pancreatitis; Pharmacoepidemi

2004
Valproic acid-induced pancreatitis in childhood epilepsy: case series and review.
    Journal of child neurology, 2004, Volume: 19, Issue:7

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Diagnosis, Differential; Dose-Response Relatio

2004
Acute pancreatitis and diabetic ketoacidosis in non-diabetic person while on treatment with sodium valproate, chlorpromazine and haloperidol.
    The Journal of the Association of Physicians of India, 2004, Volume: 52

    Topics: Acute Disease; Adult; Antimanic Agents; Bipolar Disorder; Chlorpromazine; Diabetic Ketoacidosis; Dia

2004
Acute valproate poisoning: pharmacokinetics, alteration in fatty acid metabolism, and changes during therapy.
    Journal of clinical psychopharmacology, 2005, Volume: 25, Issue:4

    Topics: Anticonvulsants; Brain Edema; Carnitine; Drug Overdose; Fatty Acids; Female; Humans; Hyperammonemia;

2005
[An acute pancreatitis in a child caused by Na-valproate].
    Acta chirurgica Iugoslavica, 2004, Volume: 51, Issue:3

    Topics: Acute Disease; Adolescent; Anticonvulsants; Female; Humans; Pancreatitis; Valproic Acid

2004
Safety and tolerability of the ketogenic diet in pediatric epilepsy: effects of valproate combination therapy.
    Epilepsia, 2005, Volume: 46, Issue:9

    Topics: Acidosis; Anticonvulsants; Child; Child, Preschool; Combined Modality Therapy; Dietary Fats; Epileps

2005
Epigastric pain.
    The Journal of emergency medicine, 2006, Volume: 30, Issue:1

    Topics: Abdominal Pain; Adult; Antimanic Agents; Bipolar Disorder; Diagnosis, Differential; Female; Gastriti

2006
The spectrum of valproic acid-associated pancreatitis.
    Pediatrics, 2006, Volume: 118, Issue:4

    Topics: Adolescent; Amylases; Anticonvulsants; Child; Child, Preschool; Female; Humans; Length of Stay; Lipa

2006
Reversible hepatotoxicity, pancreatitis, coagulation disorder and simultaneous bone marrow suppression with valproate in a 2-year-old girl.
    Seizure, 2007, Volume: 16, Issue:6

    Topics: Blood Coagulation Disorders; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Child, Pr

2007
Valproic acid-induced pancreatitis.
    Journal of gastroenterology, 2007, Volume: 42, Issue:7

    Topics: Adolescent; Adult; Anticonvulsants; Child; Databases, Factual; Female; Humans; Male; Middle Aged; Pa

2007
Acute hemorrhagic pancreatitis due to the use of valproic acid in a child.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2008, Volume: 12, Issue:2

    Topics: Acute Disease; Anticonvulsants; Child; Epilepsy, Generalized; Hemorrhage; Humans; Intellectual Disab

2008
Pancreatitis due to valproic acid.
    Lancet (London, England), 1980, May-31, Volume: 1, Issue:8179

    Topics: Child; Female; Humans; Pancreatitis; Valproic Acid

1980
Valproic acid associated pancreatitis in an adult.
    Lancet (London, England), 1981, Jan-03, Volume: 1, Issue:8210

    Topics: Age Factors; Aged; Epilepsies, Myoclonic; Humans; Male; Pancreatitis; Valproic Acid

1981
Drug-induced pancreatitis--additional review.
    Gastroenterology, 1980, Volume: 79, Issue:3

    Topics: Amylases; Humans; Methyldopa; Pancreatitis; Valproic Acid

1980
Recurrent pancreatitis induced by valproic acid. A case report and review of the literature.
    Gastroenterology, 1981, Volume: 80, Issue:4

    Topics: Adolescent; Amylases; Anticonvulsants; Humans; Male; Pancreatitis; Valproic Acid

1981
Monitoring of serum amylase levels during valproic acid therapy.
    Annals of neurology, 1982, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Amylases; Child; Child, Preschool; Humans; Middle Aged; Pancreatitis; Valproic Ac

1982
Serum amylase in patients treated with sodium valproate.
    Acta neurologica, 1982, Volume: 4, Issue:6

    Topics: Acute Disease; Adolescent; Amylases; Child; Child, Preschool; Clinical Enzyme Tests; Female; Humans;

1982
Pancreatitis associated with valproic acid therapy.
    American journal of diseases of children (1960), 1984, Volume: 138, Issue:10

    Topics: Abdomen; Adolescent; Adult; Amylases; Blood Coagulation Disorders; Child; Child, Preschool; Female;

1984
Pancreatitis during sodium valproate treatment.
    Archives of disease in childhood, 1983, Volume: 58, Issue:7

    Topics: Acute Disease; Female; Hemorrhage; Humans; Infant; Pancreatitis; Seizures, Febrile; Valproic Acid

1983
On the toxicity of valproic acid.
    American journal of diseases of children (1960), 1984, Volume: 138, Issue:10

    Topics: Adolescent; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Female; Humans; Infant;

1984
Pancreatitis associated with valproic acid therapy for epilepsy.
    Annals of neurology, 1980, Volume: 7, Issue:1

    Topics: Child; Epilepsies, Myoclonic; Humans; Male; Pancreatitis; Valproic Acid

1980
Valproic acid induced pancreatitis in children.
    Pediatrics, 1980, Volume: 65, Issue:6

    Topics: Age Factors; Child; Humans; Pancreatitis; Valproic Acid

1980
[Acute pancreatitis during anticonvulsant therapy using sodium valproinate (ergenyl)].
    Deutsche medizinische Wochenschrift (1946), 1980, Jun-20, Volume: 105, Issue:25

    Topics: Acute Disease; Adult; Female; Humans; Pancreatitis; Valproic Acid

1980
Acute pancreatitis and sodium valproate.
    The Medical journal of Australia, 1982, Oct-16, Volume: 2, Issue:8

    Topics: Acute Disease; Adult; Female; Humans; Kidney Diseases; Pancreatitis; Valproic Acid

1982
Several hematic parameters in children treated with sodium valproate.
    Acta neurologica, 1982, Volume: 4, Issue:6

    Topics: Blood Platelet Disorders; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Female; H

1982
Necrotizing pancreatitis after 10 years of therapy with valproic acid.
    Clinical pediatrics, 1995, Volume: 34, Issue:8

    Topics: Child; Humans; Male; Necrosis; Pancreatitis; Seizures; Time Factors; Valproic Acid

1995
Valproate-associated pancreatitis and cholecystitis in six mentally retarded adults.
    The Journal of clinical psychiatry, 1995, Volume: 56, Issue:11

    Topics: Adult; Anticonvulsants; Bipolar Disorder; Cholecystitis; Comorbidity; Epilepsy; Humans; Intellectual

1995
[Fatal pancreatitis associated with valproate therapy].
    Ugeskrift for laeger, 1995, Jul-31, Volume: 157, Issue:31

    Topics: Acute Disease; Adolescent; Fatal Outcome; Humans; Male; Necrosis; Pancreatitis; Valproic Acid

1995
[Drug-induced pancreatitis: experience of the Swiss Drug Adverse Effects Center (SANZ) 1981-1993].
    Schweizerische medizinische Wochenschrift, 1995, Apr-15, Volume: 125, Issue:15

    Topics: Acute Disease; Adolescent; Adult; Aged; Child; Female; Humans; Male; Middle Aged; Pancreatitis; Retr

1995
Life threatening intoxication with sodium valproate.
    Journal of toxicology. Clinical toxicology, 1995, Volume: 33, Issue:3

    Topics: Adult; Clonazepam; Coma; Female; Humans; Pancreatitis; Valproic Acid

1995
[Acute pancreatitis induced by valproic acid].
    Gastroenterologie clinique et biologique, 1994, Volume: 18, Issue:10

    Topics: Acute Disease; Adult; Epilepsy, Absence; Humans; Male; Pancreatitis; Valproic Acid

1994
Valproate-associated acute pancreatitis in a child with neuronal ceroid lipofuscinosis.
    Journal of child neurology, 1994, Volume: 9, Issue:1

    Topics: Acute Disease; Child; Female; Humans; Liver; Neuronal Ceroid-Lipofuscinoses; Pancreatitis; Seizures;

1994
Misdiagnosis of pancreatitis during valproate treatment in gastro-oesophageal reflux.
    Archives of disease in childhood, 1996, Volume: 75, Issue:4

    Topics: Adolescent; Diagnostic Errors; Gastroesophageal Reflux; Humans; Male; Pancreatitis; Valproic Acid

1996
Valproic-acid-associated pancreatitis and hepatic toxicity in children with endstage renal disease.
    Pediatric radiology, 1997, Volume: 27, Issue:2

    Topics: Adolescent; Anticonvulsants; Chemical and Drug Induced Liver Injury; Child; Fatal Outcome; Fatty Liv

1997
Multiorgan system failure caused by valproic acid toxicity.
    The American journal of emergency medicine, 1997, Volume: 15, Issue:5

    Topics: Acute Kidney Injury; Anticonvulsants; Emergencies; Humans; Liver Failure; Male; Middle Aged; Migrain

1997
On the toxicity of valproic-acid.
    Clinical nephrology, 1999, Volume: 51, Issue:3

    Topics: Acute Disease; Adult; Anticonvulsants; Epilepsy, Tonic-Clonic; Humans; Kidney Failure, Chronic; Male

1999
Recurrent acute pancreatitis associated with valproic acid use for mood stabilization.
    Journal of clinical psychopharmacology, 1999, Volume: 19, Issue:5

    Topics: Acute Disease; Adult; Antimanic Agents; Humans; Male; Pancreatitis; Schizophrenia, Paranoid; Valproi

1999
A case of chronic pancreatic insufficiency due to valproic acid in a child.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2001, Volume: 15, Issue:2

    Topics: Adolescent; Anticonvulsants; Chronic Disease; Exocrine Pancreatic Insufficiency; Follow-Up Studies;

2001
[Fatal necro-hemorrhagic pancreatitis related to sodium valproate: case report].
    Arquivos de neuro-psiquiatria, 2001, Volume: 59, Issue:3-B

    Topics: Acute Disease; Anticonvulsants; Child; Epilepsy; Fatal Outcome; Humans; Male; Necrosis; Pancreatitis

2001
Pancreatitis complicating treatment with intravenous valproic acid.
    Journal of neurology, 2002, Volume: 249, Issue:4

    Topics: Adult; Aged; Epilepsy; Female; Humans; Injections, Intravenous; Male; Middle Aged; Pancreatitis; Val

2002
Pancreatitis due to valproic acid.
    Lancet (London, England), 1979, Jun-02, Volume: 1, Issue:8127

    Topics: Child; Child, Preschool; Female; Gastritis; Humans; Male; Pancreatitis; Seizures; Valproic Acid

1979
Pancreatitis associated with valproic acid therapy.
    Pediatrics, 1979, Volume: 64, Issue:4

    Topics: Acute Disease; Child; Epilepsy, Absence; Humans; Male; Pancreatitis; Valproic Acid

1979
[An adult case of Reye like syndrome and acute pancreatitis associated with sodium valproate].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1992, Volume: 89, Issue:7

    Topics: Acute Disease; Biopsy; Humans; Liver; Male; Middle Aged; Pancreatitis; Reye Syndrome; Valproic Acid

1992
Anticonvulsant-induced chronic pancreatitis. A case report.
    The Italian journal of gastroenterology, 1992, Volume: 24, Issue:5

    Topics: Adult; Anticonvulsants; Carbamazepine; Chronic Disease; Cytochrome P-450 Enzyme System; Epilepsy; Fr

1992
Preclinical toxicology of the anticonvulsant calcium valproate.
    Toxicology, 1990, Volume: 63, Issue:2

    Topics: Animals; Anticonvulsants; Atrophy; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclini

1990
Pancreatitis in children on chronic dialysis treated with valproic acid.
    Pediatric nephrology (Berlin, Germany), 1990, Volume: 4, Issue:3

    Topics: Child; Child, Preschool; Female; Humans; Infant; Kidney Failure, Chronic; Male; Pancreatitis; Renal

1990
[Valproic acid: association of a fatal acute hepatitis and pancreatitis].
    Annales de medecine interne, 1990, Volume: 141, Issue:5

    Topics: Adult; Chemical and Drug Induced Liver Injury; Humans; Male; Pancreatitis; Valproic Acid

1990
[Proven relationship between drugs and pancreatitis].
    Deutsche medizinische Wochenschrift (1946), 1986, May-30, Volume: 111, Issue:22

    Topics: Asparaginase; Azathioprine; Diuretics; Drug-Related Side Effects and Adverse Reactions; Estrogens; H

1986
Hemorrhagic pancreatitis in a young child following valproic acid therapy. Clinical and ultrasonic assessment.
    Clinical pediatrics, 1987, Volume: 26, Issue:2

    Topics: Acute Disease; Child, Preschool; Hemorrhage; Humans; Male; Pancreatitis; Seizures; Ultrasonography;

1987
[Unapparent course of pancreatitis with pseudocyst development and cholestatic jaundice in anticonvulsive therapy with valproate].
    Klinische Wochenschrift, 1987, May-04, Volume: 65, Issue:9

    Topics: Adolescent; Cholangiopancreatography, Endoscopic Retrograde; Cholestasis, Extrahepatic; Chronic Dise

1987
Valproic acid toxicity.
    American journal of diseases of children (1960), 1985, Volume: 139, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Epilepsy; Humans; Infant; Pancreati

1985
[Acute drug-induced pancreatitis].
    Schweizerische medizinische Wochenschrift, 1985, Jun-22, Volume: 115, Issue:25

    Topics: Acute Disease; Asparaginase; Azathioprine; Chlorothiazide; Drug-Related Side Effects and Adverse Rea

1985