valproic acid has been researched along with Pancreatic Diseases in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Pancreatic Diseases: Pathological processes of the PANCREAS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Clinical data on epilepsy, characteristics of VPA treatment, risk factors for VHT, laboratory data on liver and pancreas functions, and adverse effects were collected." | 1.48 | Variants p.Q1236H and p.E1143G in mitochondrial DNA polymerase gamma POLG1 are not associated with increased risk for valproate-induced hepatotoxicity or pancreatic toxicity: A retrospective cohort study of patients with epilepsy. ( Ansakorpi, H; Eriksson, K; Haapala, P; Haataja, L; Hinttala, R; Hynynen, J; Jyrkilä, A; Kälviäinen, R; Kärppä, M; Komulainen-Ebrahim, J; Lähdetie, J; Majamaa, K; Mäkitalo, A; Myllynen, P; Pokka, T; Pylvänen, L; Rantala, H; Sokka, A; Uusimaa, J; Vieira, P; Ylikotila, P, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hynynen, J | 1 |
| Pokka, T | 1 |
| Komulainen-Ebrahim, J | 1 |
| Myllynen, P | 1 |
| Kärppä, M | 1 |
| Pylvänen, L | 1 |
| Kälviäinen, R | 1 |
| Sokka, A | 1 |
| Jyrkilä, A | 1 |
| Lähdetie, J | 1 |
| Haataja, L | 1 |
| Mäkitalo, A | 1 |
| Ylikotila, P | 1 |
| Eriksson, K | 1 |
| Haapala, P | 1 |
| Ansakorpi, H | 1 |
| Hinttala, R | 1 |
| Vieira, P | 1 |
| Majamaa, K | 1 |
| Rantala, H | 1 |
| Uusimaa, J | 1 |
| Jimenez-Rodriguezvila, M | 1 |
| Caro-Patón, A | 1 |
| Conde, M | 1 |
| Dueñas-Laita, A | 1 |
| Martin-Lorente, JL | 1 |
| Fernandez Perez de Villalain, MJ | 1 |
| Gonzalez Martinez de Zarate, JL | 1 |
| Marañon, A | 1 |
2 other studies available for valproic acid and Pancreatic Diseases
| Article | Year |
|---|---|
Variants p.Q1236H and p.E1143G in mitochondrial DNA polymerase gamma POLG1 are not associated with increased risk for valproate-induced hepatotoxicity or pancreatic toxicity: A retrospective cohort study of patients with epilepsy.
Topics: Adolescent; Adult; Alanine Transaminase; Anticonvulsants; Aspartate Aminotransferases; Chemical and | 2018 |
Side-effects of sodium valproate, mainly related to its hepatic and pancreatic toxicity.
Topics: Adolescent; Adult; Aged; Amylases; Body Weight; Chemical and Drug Induced Liver Injury; Child; Child | 1986 |