valproic acid has been researched along with Pain, Intractable in 3 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Pain, Intractable: Persistent pain that is refractory to some or all forms of treatment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with migraines have typically been given one group of medications for abortive treatment and another for preventative." | 1.31 | Use of intravenous valproate sodium in status migraine. ( Norton, J, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sindrup, SH | 2 |
| Otto, M | 2 |
| Bach, FW | 2 |
| Jensen, TS | 2 |
| Norton, J | 1 |
1 trial available for valproic acid and Pain, Intractable
| Article | Year |
|---|---|
Health-related quality of life and its predictive role for analgesic effect in patients with painful polyneuropathy.
Topics: Adult; Aged; Aged, 80 and over; Analgesia; Analgesics; Cross-Over Studies; Cyclohexanols; Drug Resis | 2007 |
2 other studies available for valproic acid and Pain, Intractable
| Article | Year |
|---|---|
Sodium valproate in painful diabetic polyneuropathy.
Topics: Anticonvulsants; Diabetic Neuropathies; Humans; Pain Measurement; Pain, Intractable; Randomized Cont | 2003 |
Use of intravenous valproate sodium in status migraine.
Topics: Acute Disease; Adult; Female; Humans; Infusions, Intravenous; Migraine Disorders; Nausea; Pain, Intr | 2000 |