valproic acid has been researched along with Obsessive-Compulsive Disorder in 15 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Obsessive-Compulsive Disorder: An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors present a case of obsessive-compulsive disorder (OCD) resistant to conventional treatments, which improved following nicotine augmentation administered as 4 mg chewing gum." | 7.73 | Nicotine augmentation for refractory obsessive-compulsive disorder. A case report. ( Biondi, M; Garavini, A; Pasquini, M, 2005) |
| "The authors present a case of obsessive-compulsive disorder (OCD) resistant to conventional treatments, which improved following nicotine augmentation administered as 4 mg chewing gum." | 3.73 | Nicotine augmentation for refractory obsessive-compulsive disorder. A case report. ( Biondi, M; Garavini, A; Pasquini, M, 2005) |
| "Sydenham's chorea is a symptom of rheumatic fever and results from an autoimmune attack on the CNS." | 2.39 | Neuropsychiatric aspects of Sydenham's chorea: a comprehensive review. ( Moore, DP, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (33.33) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lazic, SE | 1 |
| Amerio, A | 1 |
| Tonna, M | 1 |
| Odone, A | 1 |
| Stubbs, B | 1 |
| Ghaemi, SN | 1 |
| Bisol, LW | 1 |
| Lara, DR | 1 |
| Egashira, N | 1 |
| Abe, M | 1 |
| Shirakawa, A | 1 |
| Niki, T | 1 |
| Mishima, K | 1 |
| Iwasaki, K | 1 |
| Oishi, R | 1 |
| Fujiwara, M | 1 |
| Rharrabti, S | 1 |
| Aalouane, R | 1 |
| Berigan, T | 1 |
| Pasquini, M | 1 |
| Garavini, A | 1 |
| Biondi, M | 1 |
| Pallanti, S | 1 |
| DeCaria, CM | 1 |
| Grant, JE | 1 |
| Urpe, M | 1 |
| Hollander, E | 1 |
| Gulsun, M | 1 |
| Gulcat, Z | 1 |
| Aydin, H | 1 |
| Zink, M | 1 |
| Englisch, S | 1 |
| Knopf, U | 1 |
| Kuwilsky, A | 1 |
| Dressing, H | 1 |
| Deltito, JA | 1 |
| Suppes, T | 1 |
| Rush, AJ | 1 |
| Corá-Locatelli, G | 1 |
| Greenberg, BD | 1 |
| Martin, JD | 1 |
| Murphy, DL | 1 |
| Moore, DP | 1 |
| Mahendran, R | 1 |
1 review available for valproic acid and Obsessive-Compulsive Disorder
| Article | Year |
|---|---|
Neuropsychiatric aspects of Sydenham's chorea: a comprehensive review.
Topics: Adult; Autoimmune Diseases; Chorea; Comorbidity; Haloperidol; Humans; Mental Disorders; Obsessive-Co | 1996 |
14 other studies available for valproic acid and Obsessive-Compulsive Disorder
| Article | Year |
|---|---|
Analytical strategies for the marble burying test: avoiding impossible predictions and invalid p-values.
Topics: Analysis of Variance; Animals; Anxiety; Autistic Disorder; Behavior, Animal; Calcium Carbonate; Dise | 2015 |
Treatment of comorbid bipolar disorder and anxiety disorders: A great challenge to modern psychiatry.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Citalopram; Comorbidity; Humans; Mal | 2016 |
Improvement of obsessive-compulsive disorder with divalproex and lamotrigine in two patients with bipolar II disorder.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Female; Humans; Lamotrigine; Male; Obsessive-Compulsive Di | 2009 |
Effects of mood stabilizers on marble-burying behavior in mice: involvement of GABAergic system.
Topics: Animals; Antipsychotic Agents; Baclofen; Behavior, Animal; Bicuculline; Carbamazepine; Dose-Response | 2013 |
[Severe trichotillomania associated with obsessive ideation].
Topics: Adult; Antidepressive Agents; Cognitive Behavioral Therapy; Drug Therapy, Combination; Female; Human | 2012 |
Modafinil treatment of excessive sedation associated with divalproex sodium.
Topics: Adult; Antimanic Agents; Benzhydryl Compounds; Bipolar Disorder; Central Nervous System Stimulants; | 2004 |
Nicotine augmentation for refractory obsessive-compulsive disorder. A case report.
Topics: Acetylcholine; Adult; Antidepressive Agents, Tricyclic; Clomipramine; Drug Resistance; GABA Agents; | 2005 |
Reliability and validity of the pathological gambling adaptation of the Yale-Brown Obsessive-Compulsive Scale (PG-YBOCS).
Topics: Adult; Disruptive, Impulse Control, and Conduct Disorders; Female; Fluvoxamine; Gambling; Humans; Li | 2005 |
Treatment of compulsive sexual behaviour with clomipramine and valproic acid.
Topics: Adult; Antidepressive Agents, Tricyclic; Antimanic Agents; Clomipramine; Drug Administration Schedul | 2007 |
Augmentation of clozapine with valproic Acid for clozapine-induced obsessive-compulsive symptoms.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Humans; Male; O | 2007 |
Valproate pretreatment for the difficult-to-treat patient with OCD.
Topics: 1-Naphthylamine; Antidepressive Agents; Clomipramine; Drug Therapy, Combination; Fluoxetine; Humans; | 1994 |
Medication optimization during clozapine treatment.
Topics: 1-Naphthylamine; Adult; Clozapine; Drug Therapy, Combination; Humans; Lithium; Male; Obsessive-Compu | 1996 |
Valproate monotherapy in an SRI-intolerant OCD patient.
Topics: Adult; Humans; Male; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Selective Sero | 1998 |
Obsessive-compulsive symptoms with risperidone.
Topics: Antipsychotic Agents; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Fluox | 1999 |