valproic acid has been researched along with Nodding Syndrome in 4 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Nodding Syndrome: Unexplained neurologic condition characterized by episodes of atonic seizures, convulsions or staring spells with further cognitive decline.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nodding syndrome is a highly debilitating, generalized seizure disorder, affecting children in subregions of sub-Saharan Africa." | 1.56 | Dried Blood Microsampling-Based Therapeutic Drug Monitoring of Antiepileptic Drugs in Children With Nodding Syndrome and Epilepsy in Uganda and the Democratic Republic of the Congo. ( Colebunders, R; Delahaye, L; Hotterbeekx, A; Idro, R; Mandro, M; Ogwang, R; Stove, CP; Velghe, S, 2020) |
| "The primary outcome was the number of seizures in the past month (30 days)." | 1.48 | Asymptomatic malaria parasitaemia and seizure control in children with nodding syndrome; a cross-sectional study. ( Akun, P; Anguzu, R; Idro, R; Kayongo, E; Marsh, K; Newton, CRJC; Ningwa, A; Ogwang, R, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Velghe, S | 1 |
| Delahaye, L | 1 |
| Ogwang, R | 2 |
| Hotterbeekx, A | 1 |
| Colebunders, R | 1 |
| Mandro, M | 1 |
| Idro, R | 3 |
| Stove, CP | 1 |
| Anguzu, R | 1 |
| Akun, P | 1 |
| Ningwa, A | 1 |
| Kayongo, E | 1 |
| Marsh, K | 1 |
| Newton, CRJC | 1 |
| Namusoke, H | 1 |
| Abbo, C | 1 |
| Mutamba, BB | 1 |
| Kakooza-Mwesige, A | 1 |
| Opoka, RO | 1 |
| Musubire, AK | 1 |
| Mwaka, AD | 1 |
| Opar, BT | 1 |
| de Polo, G | 1 |
| Romaniello, R | 1 |
| Otim, A | 1 |
| Benjamin, K | 1 |
| Bonanni, P | 1 |
| Borgatti, R | 1 |
1 review available for valproic acid and Nodding Syndrome
| Article | Year |
|---|---|
Neurophysiological and clinical findings on Nodding Syndrome in 21 South Sudanese children and a review of the literature.
Topics: Adolescent; Anticonvulsants; Brain; Child; Electroencephalography; Female; Follow-Up Studies; Humans | 2015 |
3 other studies available for valproic acid and Nodding Syndrome
| Article | Year |
|---|---|
Dried Blood Microsampling-Based Therapeutic Drug Monitoring of Antiepileptic Drugs in Children With Nodding Syndrome and Epilepsy in Uganda and the Democratic Republic of the Congo.
Topics: Anticonvulsants; Carbamazepine; Child; Chromatography, Liquid; Democratic Republic of the Congo; Dri | 2020 |
Asymptomatic malaria parasitaemia and seizure control in children with nodding syndrome; a cross-sectional study.
Topics: Adolescent; Anticonvulsants; Antiparasitic Agents; Child; Cross-Sectional Studies; Doxycycline; Fema | 2018 |
Patients with nodding syndrome in Uganda improve with symptomatic treatment: a cross-sectional study.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Cohort Studies; Cross-Sectional Studies; Femal | 2014 |