valproic acid has been researched along with Neuroendocrine Tumors in 3 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Neuroendocrine Tumors: Tumors whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumors include ectopic hormone production (often via APUD CELLS), the presence of tumor-associated antigens, and isozyme composition.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giordano, F | 1 |
| Naimo, GD | 1 |
| Nigro, A | 1 |
| Romeo, F | 1 |
| Paolì, A | 1 |
| De Amicis, F | 1 |
| Vivacqua, A | 1 |
| Morelli, C | 1 |
| Mauro, L | 1 |
| Panno, ML | 1 |
| Sun, L | 1 |
| Qian, Q | 1 |
| Sun, G | 1 |
| Mackey, LV | 1 |
| Fuselier, JA | 1 |
| Coy, DH | 1 |
| Yu, CY | 1 |
| Arvidsson, Y | 1 |
| Johanson, V | 1 |
| Pfragner, R | 1 |
| Wängberg, B | 1 |
| Nilsson, O | 1 |
3 other studies available for valproic acid and Neuroendocrine Tumors
| Article | Year |
|---|---|
Valproic Acid Addresses Neuroendocrine Differentiation of LNCaP Cells and Maintains Cell Survival.
Topics: Cell Differentiation; Cell Proliferation; Cell Survival; Humans; Neuroendocrine Tumors; Pancreatic N | 2019 |
Valproic acid induces NET cell growth arrest and enhances tumor suppression of the receptor-targeted peptide-drug conjugate via activating somatostatin receptor type II.
Topics: Animals; Apoptosis; Camptothecin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Hist | 2016 |
Cytotoxic Effects of Valproic Acid on Neuroendocrine Tumour Cells.
Topics: Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response R | 2016 |