Page last updated: 2024-10-26

valproic acid and Neoplasms, Bone Marrow

valproic acid has been researched along with Neoplasms, Bone Marrow in 1 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

ExcerptRelevanceReference
" In this study, we investigated the effect of this anticancer drug alone and in combination with a histone deacetylase (HDAC) inhibitor, valproic acid (VPA), on a human UKF-NB-4 neuroblastoma cell line."7.78Impact of histone deacetylase inhibitor valproic acid on the anticancer effect of etoposide on neuroblastoma cells. ( Eckschlager, T; Groh, T; Hrabeta, J; Poljakova, J; Stiborova, M, 2012)
" In this study, we investigated the effect of this anticancer drug alone and in combination with a histone deacetylase (HDAC) inhibitor, valproic acid (VPA), on a human UKF-NB-4 neuroblastoma cell line."3.78Impact of histone deacetylase inhibitor valproic acid on the anticancer effect of etoposide on neuroblastoma cells. ( Eckschlager, T; Groh, T; Hrabeta, J; Poljakova, J; Stiborova, M, 2012)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Groh, T1
Hrabeta, J1
Poljakova, J1
Eckschlager, T1
Stiborova, M1

Other Studies

1 other study available for valproic acid and Neoplasms, Bone Marrow

ArticleYear
Impact of histone deacetylase inhibitor valproic acid on the anticancer effect of etoposide on neuroblastoma cells.
    Neuro endocrinology letters, 2012, Volume: 33 Suppl 3

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Bone Marrow Neoplasms; Brain Neoplasms; Cell Cycle; Ce

2012