valproic acid has been researched along with Muscular Dystrophy in 4 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Seizures were controlled in a few weeks with intramuscular synthetic ACTH, followed by valproic acid." | 3.81 | LAMA2-related congenital muscular dystrophy complicated by West syndrome. ( Camacho, A; de Aragón, AM; Dekomien, G; Hernández-Laín, A; Núñez, N; Simón, R, 2015) |
| "Muscular dystrophies are debilitating neuromuscular disorders for which no cure exists." | 1.62 | Valproic acid stimulates myogenesis in pluripotent stem cell-derived mesodermal progenitors in a NOTCH-dependent manner. ( Breuls, N; Carai, P; Deroose, C; Garrido, GM; Giarratana, N; Heymans, S; Ranga, A; Sampaolesi, M; Yedigaryan, L, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Breuls, N | 1 |
| Giarratana, N | 1 |
| Yedigaryan, L | 1 |
| Garrido, GM | 1 |
| Carai, P | 1 |
| Heymans, S | 1 |
| Ranga, A | 1 |
| Deroose, C | 1 |
| Sampaolesi, M | 1 |
| Camacho, A | 1 |
| Núñez, N | 1 |
| Dekomien, G | 1 |
| Hernández-Laín, A | 1 |
| de Aragón, AM | 1 |
| Simón, R | 1 |
| Larochelle, N | 1 |
| Teng, Q | 1 |
| Gilbert, R | 1 |
| Deol, JR | 1 |
| Karpati, G | 1 |
| Holland, PC | 1 |
| Nalbantoglu, J | 1 |
| Murphy, DG | 1 |
| Davidson, WS | 1 |
4 other studies available for valproic acid and Muscular Dystrophy
| Article | Year |
|---|---|
Valproic acid stimulates myogenesis in pluripotent stem cell-derived mesodermal progenitors in a NOTCH-dependent manner.
Topics: Animals; Cell Differentiation; Cell Lineage; Cells, Cultured; Coculture Techniques; Disease Models, | 2021 |
LAMA2-related congenital muscular dystrophy complicated by West syndrome.
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Brain; Child, Preschool; Electroencephalography; Human | 2015 |
Modulation of coxsackie and adenovirus receptor expression for gene transfer to normal and dystrophic skeletal muscle.
Topics: Adenoviridae; Animals; Coxsackie and Adenovirus Receptor-Like Membrane Protein; Dystrophin; Mice; Mi | 2010 |
Inhibition studies on chicken muscle aldose reductase.
Topics: Aldehyde Reductase; Animals; Chickens; Kinetics; Male; Muscles; Muscular Dystrophies; Sugar Alcohol | 1985 |