valproic acid has been researched along with Meningioma in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Meningioma: A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Hyperammonemic coma is determined through a complicated differential diagnosis, and although it can also be induced as a side effect of valproate (VPA), this cause is frequently unrecognized or confused with upper gastrointestinal hemorrhage (UGH)-induced hepatic encephalopathy." | 2.55 | Hyperammonemic coma after craniotomy: Hepatic encephalopathy from upper gastrointestinal hemorrhage or valproate side effect?: Case report and literature review. ( Gao, L; Guo, X; Wei, J; Xing, B; Xu, Z, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, X | 1 |
| Wei, J | 1 |
| Gao, L | 1 |
| Xing, B | 1 |
| Xu, Z | 1 |
| Chiou, HY | 1 |
| Lai, WK | 1 |
| Huang, LC | 1 |
| Huang, SM | 1 |
| Chueh, SH | 1 |
| Ma, HI | 1 |
| Hueng, DY | 1 |
1 review available for valproic acid and Meningioma
| Article | Year |
|---|---|
Hyperammonemic coma after craniotomy: Hepatic encephalopathy from upper gastrointestinal hemorrhage or valproate side effect?: Case report and literature review.
Topics: Anticonvulsants; Coma; Craniotomy; Diagnosis, Differential; Female; Gastrointestinal Hemorrhage; Hep | 2017 |
1 other study available for valproic acid and Meningioma
| Article | Year |
|---|---|
Valproic acid promotes radiosensitization in meningioma stem-like cells.
Topics: Apoptosis; Cell Cycle Checkpoints; Cell Differentiation; Down-Regulation; Humans; Meningioma; Neopla | 2015 |