valproic acid has been researched along with Malaria in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Eight hours after 2 of 3 prophylactic antimalarial treatments with mefloquine generalized tonic-clonic seizures occurred." | 3.68 | [Suspected convulsive side-effect of mefloquine (Lariam)]. ( Besser, R; Krämer, G, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lev, D | 1 |
| Yahalom, G | 1 |
| Rabinowicz, S | 1 |
| Leshem, E | 1 |
| Schwartz, E | 1 |
| Besser, R | 1 |
| Krämer, G | 1 |
2 other studies available for valproic acid and Malaria
| Article | Year |
|---|---|
Opsoclonus-myoclonus as a presentation of post-malaria neurological syndrome.
Topics: Anticonvulsants; Electroencephalography; Humans; Israel; Liberia; Malaria; Male; Middle Aged; Opsocl | 2020 |
[Suspected convulsive side-effect of mefloquine (Lariam)].
Topics: Adult; Drug Therapy, Combination; Electroencephalography; Epilepsies, Myoclonic; Epilepsy, Tonic-Clo | 1991 |