valproic acid has been researched along with Magnesium Deficiency in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Magnesium Deficiency: A nutritional condition produced by a deficiency of magnesium in the diet, characterized by anorexia, nausea, vomiting, lethargy, and weakness. Symptoms are paresthesias, muscle cramps, irritability, decreased attention span, and mental confusion, possibly requiring months to appear. Deficiency of body magnesium can exist even when serum values are normal. In addition, magnesium deficiency may be organ-selective, since certain tissues become deficient before others. (Harrison's Principles of Internal Medicine, 12th ed, p1936)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shi, YJ | 1 |
| Gong, XW | 1 |
| Gong, HQ | 1 |
| Liang, PJ | 1 |
| Zhang, PM | 1 |
| Lu, QC | 1 |
| Dreier, JP | 1 |
| Heinemann, U | 1 |
2 other studies available for valproic acid and Magnesium Deficiency
| Article | Year |
|---|---|
Effect of the entorhinal cortex on ictal discharges in low-Mg²⁺-induced epileptic hippocampal slice models.
Topics: Animals; Anticonvulsants; CA1 Region, Hippocampal; Data Interpretation, Statistical; Electroencephal | 2014 |
Late low magnesium-induced epileptiform activity in rat entorhinal cortex slices becomes insensitive to the anticonvulsant valproic acid.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Electrophysiology; Epilepsy; Hippocampus; In | 1990 |