valproic acid has been researched along with Macular Degeneration in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Macular Degeneration: Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aims of our study were to evaluate whether color vision and macular function are impaired in epileptic adolescents, to study if the monotherapy with valproic acid (VPA) and carbamazepine (CBZ) can affect color vision and macular function and to determine the possible relationship between color vision, retinal function and antiepileptic drugs (AEDs) dosage and their serum concentrations." | 2.72 | Color vision and macular recovery time in epileptic adolescents treated with valproate and carbamazepine. ( Chiarelli, F; Gallenga, PE; Iannetti, P; Lobefalo, L; Spalice, A; Tocco, AM; Verrotti, A, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SanGiovanni, JP | 1 |
| Rosen, R | 1 |
| Kaushal, S | 1 |
| Verrotti, A | 1 |
| Lobefalo, L | 1 |
| Tocco, AM | 1 |
| Spalice, A | 1 |
| Gallenga, PE | 1 |
| Chiarelli, F | 1 |
| Iannetti, P | 1 |
1 trial available for valproic acid and Macular Degeneration
| Article | Year |
|---|---|
Color vision and macular recovery time in epileptic adolescents treated with valproate and carbamazepine.
Topics: Adolescent; Analysis of Variance; Anticonvulsants; Carbamazepine; Color Perception; Epilepsy; Female | 2006 |
1 other study available for valproic acid and Macular Degeneration
| Article | Year |
|---|---|
Application and interpretation of genome-wide association (GWA) studies for informing pharmacogenomic research - examples from the field of age-related macular degeneration.
Topics: GABA Agents; Gene Regulatory Networks; Genetic Predisposition to Disease; Genome-Wide Association St | 2014 |