valproic acid has been researched along with Macrocephaly in 1 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Go, HS | 1 |
| Kim, KC | 1 |
| Choi, CS | 1 |
| Jeon, SJ | 1 |
| Kwon, KJ | 1 |
| Han, SH | 1 |
| Lee, J | 1 |
| Cheong, JH | 1 |
| Ryu, JH | 1 |
| Kim, CH | 1 |
| Ko, KH | 1 |
| Shin, CY | 1 |
1 other study available for valproic acid and Macrocephaly
| Article | Year |
|---|---|
Prenatal exposure to valproic acid increases the neural progenitor cell pool and induces macrocephaly in rat brain via a mechanism involving the GSK-3β/β-catenin pathway.
Topics: Animals; Anticonvulsants; Antimetabolites; beta Catenin; Blotting, Western; Bromodeoxyuridine; Cell | 2012 |