valproic acid has been researched along with Leukemia, Smoldering in 3 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-one elderly AML/RAEB patients (AML n=25; RAEB n=6) with a high rate of comorbidity were entered in a phase II study with low-dose cytarabine (Ara-C) and VPA." | 2.76 | Hematologic improvement and response in elderly AML/RAEB patients treated with valproic acid and low-dose Ara-C. ( Alvaro, MG; Baraldi, A; Ciravegna, G; Corsetti, MT; De Paoli, L; Gatto, S; Levis, A; Perticone, S; Pietrasanta, D; Pini, M; Primon, V; Salvi, F; Tonso, A; Zallio, F, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Möller, I | 1 |
| Blum, S | 1 |
| Gattermann, N | 1 |
| Haas, R | 1 |
| Habersang, K | 1 |
| Germing, U | 1 |
| Kuendgen, A | 2 |
| Corsetti, MT | 1 |
| Salvi, F | 1 |
| Perticone, S | 1 |
| Baraldi, A | 1 |
| De Paoli, L | 1 |
| Gatto, S | 1 |
| Pietrasanta, D | 1 |
| Pini, M | 1 |
| Primon, V | 1 |
| Zallio, F | 1 |
| Tonso, A | 1 |
| Alvaro, MG | 1 |
| Ciravegna, G | 1 |
| Levis, A | 1 |
1 trial available for valproic acid and Leukemia, Smoldering
| Article | Year |
|---|---|
Hematologic improvement and response in elderly AML/RAEB patients treated with valproic acid and low-dose Ara-C.
Topics: Aged; Aged, 80 and over; Anemia, Refractory, with Excess of Blasts; Anticonvulsants; Antimetabolites | 2011 |
2 other studies available for valproic acid and Leukemia, Smoldering
| Article | Year |
|---|---|
Repeated responses of an elderly patient with high-risk myelodysplastic syndrome to sequential therapy with tipifarnib, 5-azacitidine, and decitabine.
Topics: Aged; Anemia, Refractory, with Excess of Blasts; Azacitidine; Benzene; Decitabine; DNA (Cytosine-5-) | 2009 |
An inexpensive way to treat elderly patients with high-risk MDS or AML.
Topics: Anemia, Refractory, with Excess of Blasts; Anticonvulsants; Antimetabolites, Antineoplastic; Cytarab | 2011 |