Page last updated: 2024-10-26

valproic acid and Leukemia, Megakaryocytic

valproic acid has been researched along with Leukemia, Megakaryocytic in 2 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

ExcerptRelevanceReference
"Acute megakaryocytic leukemia (AMegL) is a biologically heterogenous subtype of acute myeloid leukemia (AML) that arises from megakaryocytes."2.53Acute megakaryocytic leukemia: What have we learned. ( Giri, S; Hahn, AW; Li, B; Martin, MG; Pathak, R; Prouet, P, 2016)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Caldwell, JT1
Edwards, H1
Dombkowski, AA1
Buck, SA1
Matherly, LH1
Ge, Y1
Taub, JW1
Hahn, AW1
Li, B1
Prouet, P1
Giri, S1
Pathak, R1
Martin, MG1

Reviews

1 review available for valproic acid and Leukemia, Megakaryocytic

ArticleYear
Acute megakaryocytic leukemia: What have we learned.
    Blood reviews, 2016, Volume: 30, Issue:1

    Topics: Antineoplastic Agents; Aurora Kinase A; Azepines; Chromosome Aberrations; Chromosomes, Human, Pair 3

2016

Other Studies

1 other study available for valproic acid and Leukemia, Megakaryocytic

ArticleYear
Overexpression of GATA1 confers resistance to chemotherapy in acute megakaryocytic Leukemia.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cells, Cultured; Child; Child, Preschool; Drug Resis

2013