valproic acid has been researched along with Leukemia, Megakaryocytic in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Excerpt | Relevance | Reference |
---|---|---|
"Acute megakaryocytic leukemia (AMegL) is a biologically heterogenous subtype of acute myeloid leukemia (AML) that arises from megakaryocytes." | 2.53 | Acute megakaryocytic leukemia: What have we learned. ( Giri, S; Hahn, AW; Li, B; Martin, MG; Pathak, R; Prouet, P, 2016) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Caldwell, JT | 1 |
Edwards, H | 1 |
Dombkowski, AA | 1 |
Buck, SA | 1 |
Matherly, LH | 1 |
Ge, Y | 1 |
Taub, JW | 1 |
Hahn, AW | 1 |
Li, B | 1 |
Prouet, P | 1 |
Giri, S | 1 |
Pathak, R | 1 |
Martin, MG | 1 |
1 review available for valproic acid and Leukemia, Megakaryocytic
Article | Year |
---|---|
Acute megakaryocytic leukemia: What have we learned.
Topics: Antineoplastic Agents; Aurora Kinase A; Azepines; Chromosome Aberrations; Chromosomes, Human, Pair 3 | 2016 |
1 other study available for valproic acid and Leukemia, Megakaryocytic
Article | Year |
---|---|
Overexpression of GATA1 confers resistance to chemotherapy in acute megakaryocytic Leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cells, Cultured; Child; Child, Preschool; Drug Resis | 2013 |