valproic acid has been researched along with Leishmaniasis, Visceral in 1 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Leishmaniasis, Visceral: A chronic disease caused by LEISHMANIA DONOVANI and transmitted by the bite of several sandflies of the genera Phlebotomus and Lutzomyia. It is commonly characterized by fever, chills, vomiting, anemia, hepatosplenomegaly, leukopenia, hypergammaglobulinemia, emaciation, and an earth-gray color of the skin. The disease is classified into three main types according to geographic distribution: Indian, Mediterranean (or infantile), and African.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There is currently no satisfactory treatment for visceral leishmaniasis; the disease is thus in desperate need of novel drugs." | 1.51 | A nanodelivered Vorinostat derivative is a promising oral compound for the treatment of visceral leishmaniasis. ( Belmonte-Reche, E; Corpas-López, V; de Pedro, N; Díaz-Gavilán, M; Franco-Montalbán, F; Gómez-Vidal, JA; López-Viota, J; López-Viota, M; Martín-Sánchez, J; Merino-Espinosa, G; Morillas-Márquez, F; Pérez-Del Palacio, J, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Corpas-López, V | 1 |
| Díaz-Gavilán, M | 1 |
| Franco-Montalbán, F | 1 |
| Merino-Espinosa, G | 1 |
| López-Viota, M | 1 |
| López-Viota, J | 1 |
| Belmonte-Reche, E | 1 |
| Pérez-Del Palacio, J | 1 |
| de Pedro, N | 1 |
| Gómez-Vidal, JA | 1 |
| Morillas-Márquez, F | 1 |
| Martín-Sánchez, J | 1 |
1 other study available for valproic acid and Leishmaniasis, Visceral
| Article | Year |
|---|---|
A nanodelivered Vorinostat derivative is a promising oral compound for the treatment of visceral leishmaniasis.
Topics: Administration, Oral; Anilides; Animals; Antiprotozoal Agents; Drug Delivery Systems; Female; Gold; | 2019 |