valproic acid has been researched along with Kidney Failure in 8 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Kidney Failure: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We included patients who had a diagnosis of bipolar disorder and were prescribed lithium (n = 2148), valproate (n = 1670), olanzapine (n = 1477), or quetiapine (n = 1376) as maintenance mood stabilizer treatment." | 3.83 | Adverse Renal, Endocrine, Hepatic, and Metabolic Events during Maintenance Mood Stabilizer Treatment for Bipolar Disorder: A Population-Based Cohort Study. ( Geddes, JR; Hayes, JF; King, M; Marston, L; Osborn, DP; Walters, K, 2016) |
| "Although Fanconi syndrome is rare in patients with epilepsy treated with sodium valproate (VPA), the prevalence might be higher in children with severe motor and intellectual disabilities (SMID)." | 1.43 | Outcome of renal proximal tubular dysfunction with Fanconi syndrome caused by sodium valproate. ( Sato, S; Watanabe, T; Yamazaki, S; Yoshikawa, H, 2016) |
| "Gabapentin is an antiepileptic agent that is indicated for use as adjunctive therapy for partial seizures." | 1.30 | A case of sustained massive gabapentin overdose without serious side effects. ( Radtke, RA; St Clair, EW; Verma, A, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishikawa, M | 1 |
| Uchida, M | 1 |
| Asakawa, T | 1 |
| Suzuki, S | 1 |
| Yamazaki, S | 2 |
| Shiko, Y | 1 |
| Kawasaki, Y | 1 |
| Suzuki, T | 1 |
| Ishii, I | 1 |
| Rej, S | 1 |
| Herrmann, N | 1 |
| Gruneir, A | 1 |
| McArthur, E | 1 |
| Jeyakumar, N | 1 |
| Muanda, FT | 1 |
| Harel, Z | 1 |
| Dixon, S | 1 |
| Garg, AX | 1 |
| Kuo, SC | 1 |
| Yeh, YW | 1 |
| Chen, CY | 1 |
| Yeh, CB | 1 |
| Tzeng, NS | 1 |
| Mao, WC | 1 |
| Moss, MC | 1 |
| Kozlowski, T | 1 |
| Dupuis, R | 1 |
| Detwiler, R | 1 |
| Lee, RM | 1 |
| Deyo, JC | 1 |
| Watanabe, T | 1 |
| Sato, S | 1 |
| Yoshikawa, H | 1 |
| Hayes, JF | 1 |
| Marston, L | 1 |
| Walters, K | 1 |
| Geddes, JR | 1 |
| King, M | 1 |
| Osborn, DP | 1 |
| Verma, A | 1 |
| St Clair, EW | 1 |
| Radtke, RA | 1 |
| Hurkacz, M | 1 |
| Wiela-HojeĊska, A | 1 |
| Orzechowska-Juzwenko, K | 1 |
| Kozik, A | 1 |
| Unolt, J | 1 |
8 other studies available for valproic acid and Kidney Failure
| Article | Year |
|---|---|
A novel method for predicting the unbound valproic acid concentration.
Topics: Anticonvulsants; Epilepsy; Humans; Renal Insufficiency; Retrospective Studies; Valproic Acid | 2023 |
Association of Lithium Use and a Higher Serum Concentration of Lithium With the Risk of Declining Renal Function in Older Adults: A Population-Based Cohort Study.
Topics: Aged; Antimanic Agents; Humans; Kidney; Lithium; Longitudinal Studies; Male; Propensity Score; Renal | 2020 |
Repeated adverse hematologic reactions associated with valproic acid use in a patient with acquired renal insufficiency.
Topics: Female; GABA Agents; Hematologic Diseases; Humans; Middle Aged; Renal Insufficiency; Valproic Acid | 2013 |
Lithium use for bipolar disorder post renal transplant: is mood stabilization without toxicity possible?
Topics: Biopsy; Bipolar Disorder; Cyclosporine; Female; Glomerular Filtration Rate; Humans; Kidney Transplan | 2014 |
Outcome of renal proximal tubular dysfunction with Fanconi syndrome caused by sodium valproate.
Topics: Anticonvulsants; Child; Child, Preschool; Epilepsy; Fanconi Syndrome; Female; Follow-Up Studies; Hum | 2016 |
Adverse Renal, Endocrine, Hepatic, and Metabolic Events during Maintenance Mood Stabilizer Treatment for Bipolar Disorder: A Population-Based Cohort Study.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Cardiovascular Diseases; Chemical an | 2016 |
A case of sustained massive gabapentin overdose without serious side effects.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cognition; Cyclohexanecarboxylic Acids; Drug Overdose; Epi | 1999 |
[Monitoring of renal function in epileptic children and teenagers treated with valproic acid or carbamazepine in concomitant therapy with tiagabine].
Topics: Acetylglucosaminidase; Adolescent; Adult; Anticonvulsants; beta 2-Microglobulin; Carbamazepine; Case | 2001 |