valproic acid has been researched along with Ischemic Stroke in 3 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Ischemic Stroke: Stroke due to BRAIN ISCHEMIA resulting in interruption or reduction of blood flow to a part of the brain. When obstruction is due to a BLOOD CLOT formed within in a cerebral blood vessel it is a thrombotic stroke. When obstruction is formed elsewhere and moved to block a cerebral blood vessel (see CEREBRAL EMBOLISM) it is referred to as embolic stroke. Wake-up stroke refers to ischemic stroke occurring during sleep while cryptogenic stroke refers to ischemic stroke of unknown origin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous studies have shown the neuroprotective effects of the valproic acid (2-n-propylpentanoic acid, VPA) against ischemic stroke, but its effects on the ischemia-induced formation of astrogliosis and glial scar are still unknown." | 8.12 | Valproic Acid Inhibits Glial Scar Formation after Ischemic Stroke. ( Gao, X; Guo, Y; He, YY; Zeb, S; Zhang, HL; Zhou, XY; Zhu, YM, 2022) |
| "Previous studies have shown the neuroprotective effects of the valproic acid (2-n-propylpentanoic acid, VPA) against ischemic stroke, but its effects on the ischemia-induced formation of astrogliosis and glial scar are still unknown." | 4.12 | Valproic Acid Inhibits Glial Scar Formation after Ischemic Stroke. ( Gao, X; Guo, Y; He, YY; Zeb, S; Zhang, HL; Zhou, XY; Zhu, YM, 2022) |
| "In this propensity score-weighted population-based retrospective cohort study, we used competing risk regression analyses to determine the risks of ischemic stroke, venous thromboembolism, and death in DOAC recipients taking CYP/P-gp-modulating antiseizure medications (phenytoin, valproate, levetiracetam, carbamazepine, or phenobarbital) versus those taking CYP/P-gp-neutral antiseizure medications (pregabalin, gabapentin, or clobazam)." | 4.12 | Thromboembolic Risks with Concurrent Direct Oral Anticoagulants and Antiseizure Medications: A Population-Based Analysis. ( Chan, HH; Chan, HY; Ip, BY; Ko, H; Lau, AY; Lau, LH; Leng, X; Leung, H; Leung, TW; Mok, VC; Soo, YO; Wong, GL; Yip, TC, 2022) |
| "Stroke is the leading cause of epilepsy in the elderly, ahead of degenerative diseases, tumors and head injuries." | 1.91 | Post-stroke seizures: risk factors and management after ischemic stroke. ( Derbali, H; Mansour, M; Messelmani, M; Mrissa, N; Mrissa, R; Ouerdiene, A; Zaouali, J, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, X | 1 |
| Zeb, S | 1 |
| He, YY | 1 |
| Guo, Y | 1 |
| Zhu, YM | 1 |
| Zhou, XY | 1 |
| Zhang, HL | 1 |
| Ip, BY | 3 |
| Ko, H | 3 |
| Wong, GL | 3 |
| Yip, TC | 3 |
| Lau, LH | 3 |
| Lau, AY | 3 |
| Leng, X | 3 |
| Leung, H | 3 |
| Chan, HH | 3 |
| Chan, HY | 3 |
| Mok, VC | 3 |
| Soo, YO | 3 |
| Leung, TW | 3 |
| Ouerdiene, A | 1 |
| Messelmani, M | 1 |
| Derbali, H | 1 |
| Mansour, M | 1 |
| Zaouali, J | 1 |
| Mrissa, N | 1 |
| Mrissa, R | 1 |
3 other studies available for valproic acid and Ischemic Stroke
| Article | Year |
|---|---|
Valproic Acid Inhibits Glial Scar Formation after Ischemic Stroke.
Topics: Animals; Astrocytes; Brain Ischemia; Glial Fibrillary Acidic Protein; Gliosis; Histones; Ischemic St | 2022 |
Thromboembolic Risks with Concurrent Direct Oral Anticoagulants and Antiseizure Medications: A Population-Based Analysis.
Topics: Anticoagulants; Humans; Ischemic Stroke; Levetiracetam; Phenytoin; Retrospective Studies; Valproic A | 2022 |
Thromboembolic Risks with Concurrent Direct Oral Anticoagulants and Antiseizure Medications: A Population-Based Analysis.
Topics: Anticoagulants; Humans; Ischemic Stroke; Levetiracetam; Phenytoin; Retrospective Studies; Valproic A | 2022 |
Thromboembolic Risks with Concurrent Direct Oral Anticoagulants and Antiseizure Medications: A Population-Based Analysis.
Topics: Anticoagulants; Humans; Ischemic Stroke; Levetiracetam; Phenytoin; Retrospective Studies; Valproic A | 2022 |
Thromboembolic Risks with Concurrent Direct Oral Anticoagulants and Antiseizure Medications: A Population-Based Analysis.
Topics: Anticoagulants; Humans; Ischemic Stroke; Levetiracetam; Phenytoin; Retrospective Studies; Valproic A | 2022 |
Thromboembolic Risks with Concurrent Direct Oral Anticoagulants and Antiseizure Medications: A Population-Based Analysis.
Topics: Anticoagulants; Humans; Ischemic Stroke; Levetiracetam; Phenytoin; Retrospective Studies; Valproic A | 2022 |
Thromboembolic Risks with Concurrent Direct Oral Anticoagulants and Antiseizure Medications: A Population-Based Analysis.
Topics: Anticoagulants; Humans; Ischemic Stroke; Levetiracetam; Phenytoin; Retrospective Studies; Valproic A | 2022 |
Thromboembolic Risks with Concurrent Direct Oral Anticoagulants and Antiseizure Medications: A Population-Based Analysis.
Topics: Anticoagulants; Humans; Ischemic Stroke; Levetiracetam; Phenytoin; Retrospective Studies; Valproic A | 2022 |
Thromboembolic Risks with Concurrent Direct Oral Anticoagulants and Antiseizure Medications: A Population-Based Analysis.
Topics: Anticoagulants; Humans; Ischemic Stroke; Levetiracetam; Phenytoin; Retrospective Studies; Valproic A | 2022 |
Thromboembolic Risks with Concurrent Direct Oral Anticoagulants and Antiseizure Medications: A Population-Based Analysis.
Topics: Anticoagulants; Humans; Ischemic Stroke; Levetiracetam; Phenytoin; Retrospective Studies; Valproic A | 2022 |
Post-stroke seizures: risk factors and management after ischemic stroke.
Topics: Aged; Epilepsy; Female; Humans; Infarction, Middle Cerebral Artery; Ischemic Stroke; Male; Middle Ag | 2023 |