valproic acid has been researched along with Ischemic Attack, Transient in 7 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The data suggest that this rat cardiac arrest model may be a valuable tool for investigating the pathophysiologic mechanisms of posthypoxic myoclonus and for developing new therapeutic strategies for treating the disorder." | 1.29 | Novel rat cardiac arrest model of posthypoxic myoclonus. ( Hussong, MJ; Matsumoto, RR; Schwartz, PH; Truong, DD; Wasterlain, CG, 1994) |
| "Seizures were attenuated or blocked by treatment with carbamazepine or sodium valproate." | 1.29 | Audiogenic seizures following global ischemia induced by chest compression in Long-Evans rats. ( Iyer, V; Keelen, P; Miller, J; Payne, RS; Reid, KH; Schurr, A; Tseng, M; Young, C, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Z | 1 |
| Leng, Y | 2 |
| Tsai, LK | 1 |
| Leeds, P | 1 |
| Chuang, DM | 2 |
| Xuan, A | 1 |
| Long, D | 1 |
| Li, J | 1 |
| Ji, W | 1 |
| Hong, L | 1 |
| Zhang, M | 1 |
| Zhang, W | 1 |
| Chabwine, JN | 1 |
| Rossetti, AR | 1 |
| Hirt, L | 1 |
| Kuntzer, T | 1 |
| Schluep, M | 1 |
| Michel, P | 1 |
| Démonet, JF | 1 |
| du Pasquier, RA | 1 |
| Vingerhoets, FG | 1 |
| Ren, M | 1 |
| Jeong, M | 1 |
| Leeds, PR | 1 |
| Truong, DD | 1 |
| Matsumoto, RR | 1 |
| Schwartz, PH | 1 |
| Hussong, MJ | 1 |
| Wasterlain, CG | 1 |
| Reid, KH | 1 |
| Young, C | 1 |
| Schurr, A | 1 |
| Tseng, M | 1 |
| Payne, RS | 1 |
| Keelen, P | 1 |
| Miller, J | 1 |
| Iyer, V | 1 |
| Minato, H | 1 |
| Kikuta, C | 1 |
| Fujitani, B | 1 |
| Masuda, Y | 1 |
7 other studies available for valproic acid and Ischemic Attack, Transient
| Article | Year |
|---|---|
Valproic acid attenuates blood-brain barrier disruption in a rat model of transient focal cerebral ischemia: the roles of HDAC and MMP-9 inhibition.
Topics: Animals; Blood-Brain Barrier; Blotting, Western; Body Water; Brain Chemistry; Brain Edema; Butyrates | 2011 |
Neuroprotective effects of valproic acid following transient global ischemia in rats.
Topics: Acetylation; Animals; Blotting, Western; Cell Death; Cognition Disorders; Enzyme-Linked Immunosorben | 2012 |
[Neurology].
Topics: Antibodies, Monoclonal; Anticonvulsants; Atrial Fibrillation; Carbamates; Chronic Disease; Deep Brai | 2012 |
Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction.
Topics: Acetylation; Animals; Behavior, Animal; Caspase 3; Caspases; Cerebral Cortex; Cerebral Infarction; D | 2004 |
Novel rat cardiac arrest model of posthypoxic myoclonus.
Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Anticonvulsants; Clonazepam; Disease Models, Ani | 1994 |
Audiogenic seizures following global ischemia induced by chest compression in Long-Evans rats.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Behavior, Animal; Biomechanical Phenomena; Blood Glu | 1996 |
Protective effect of zonisamide, an antiepileptic drug, against transient focal cerebral ischemia with middle cerebral artery occlusion-reperfusion in rats.
Topics: Animals; Anticonvulsants; Arterial Occlusive Diseases; Body Temperature; Carbamazepine; Cerebral Art | 1997 |