valproic acid has been researched along with Intraocular Pressure in 5 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to compare the effectiveness of combination therapy consisting of low-dose mitomycin C (MMC) and valproic acid (VPA) against high-dose MMC for improving the scar phenotype in minimally invasive glaucoma surgery (MIGS)." | 8.12 | Effects of Valproic Acid and Mitomycin C Combination Therapy in a Rabbit Model of Minimally Invasive Glaucoma Surgery. ( Chu, SWL; Ibrahim, FI; Seet, LF; Teng, X; Toh, LZ; Wong, TT; Yap, ZL, 2022) |
| "This study aimed to compare the effectiveness of combination therapy consisting of low-dose mitomycin C (MMC) and valproic acid (VPA) against high-dose MMC for improving the scar phenotype in minimally invasive glaucoma surgery (MIGS)." | 4.12 | Effects of Valproic Acid and Mitomycin C Combination Therapy in a Rabbit Model of Minimally Invasive Glaucoma Surgery. ( Chu, SWL; Ibrahim, FI; Seet, LF; Teng, X; Toh, LZ; Wong, TT; Yap, ZL, 2022) |
| "To determine the effect of valproic acid (VPA) on bleb morphology and scar characteristics in a rabbit model of minimally invasive glaucoma surgery (MIGS)." | 4.12 | Effect of valproic acid on functional bleb morphology in a rabbit model of minimally invasive surgery. ( Chu, SW; Ibrahim, FI; Seet, LF; Toh, LZ; Wong, TT; Yap, ZL, 2022) |
| "In vehicle-treated animals, ocular hypertension resulted in a 29." | 1.40 | Acetylation preserves retinal ganglion cell structure and function in a chronic model of ocular hypertension. ( Alsarraf, O; Chou, CJ; Crosson, CE; Dahrouj, M; Fan, J; Yates, PW, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Seet, LF | 2 |
| Yap, ZL | 2 |
| Chu, SWL | 1 |
| Toh, LZ | 2 |
| Ibrahim, FI | 2 |
| Teng, X | 1 |
| Wong, TT | 2 |
| Chu, SW | 1 |
| Mahalingam, K | 1 |
| Chaurasia, AK | 1 |
| Gowtham, L | 1 |
| Gupta, S | 1 |
| Somarajan, BI | 1 |
| Velpandian, T | 1 |
| Sihota, R | 1 |
| Gupta, V | 1 |
| Alsarraf, O | 1 |
| Fan, J | 1 |
| Dahrouj, M | 1 |
| Chou, CJ | 1 |
| Yates, PW | 1 |
| Crosson, CE | 1 |
| García-Aparicio, AM | 1 |
| Leal, MA | 1 |
| Platero, M | 1 |
| Beneyto, P | 1 |
1 trial available for valproic acid and Intraocular Pressure
| Article | Year |
|---|---|
Therapeutic potential of valproic acid in advanced glaucoma: A pilot study.
Topics: Administration, Oral; Dose-Response Relationship, Drug; Electroretinography; Female; Follow-Up Studi | 2018 |
4 other studies available for valproic acid and Intraocular Pressure
| Article | Year |
|---|---|
Effects of Valproic Acid and Mitomycin C Combination Therapy in a Rabbit Model of Minimally Invasive Glaucoma Surgery.
Topics: Animals; Collagen Type I, alpha 1 Chain; Glaucoma; Intraocular Pressure; Mitomycin; Rabbits; Valproi | 2022 |
Effect of valproic acid on functional bleb morphology in a rabbit model of minimally invasive surgery.
Topics: Animals; Collagen; Conjunctiva; Glaucoma; Humans; Intraocular Pressure; Minimally Invasive Surgical | 2022 |
Acetylation preserves retinal ganglion cell structure and function in a chronic model of ocular hypertension.
Topics: Acetylation; Acetyltransferases; Animals; Blotting, Western; Chronic Disease; Disease Models, Animal | 2014 |
[Behçet's disease in treatment with cyclosporine and seizures: diagnostic dilemma].
Topics: Adrenal Cortex Hormones; Adult; Anticonvulsants; Behcet Syndrome; Cyclosporins; Electroretinography; | 2007 |