Page last updated: 2024-10-26

valproic acid and Interstitial Nephritis

valproic acid has been researched along with Interstitial Nephritis in 11 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

ExcerptRelevanceReference
"Levetiracetam (LEV), used for both partial and generalized seizures, is a frequently preferred antiepileptic because of its few side effects."7.80Hypokalemia and hypomagnesaemia related to levetiracetam use. ( Aksoy, D; Cevik, B; Kurt, S; Pekdas, E; Solmaz, V, 2014)
"Levetiracetam (LEV), used for both partial and generalized seizures, is a frequently preferred antiepileptic because of its few side effects."3.80Hypokalemia and hypomagnesaemia related to levetiracetam use. ( Aksoy, D; Cevik, B; Kurt, S; Pekdas, E; Solmaz, V, 2014)
"Although renal Fanconi syndrome resulting from valproate (VPA) has occasionally been reported, the detailed clinical characteristics of this disease remain unclear."1.33Secondary renal Fanconi syndrome caused by valproate therapy. ( Abe, T; Abe, Y; Watanabe, T; Yamazaki, S; Yoshikawa, H, 2005)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's4 (36.36)18.2507
2000's3 (27.27)29.6817
2010's2 (18.18)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Tanabe, K1
Matsuoka-Uchiyama, N1
Mifune, T1
Kawakita, C1
Sugiyama, H1
Wada, J1
Moss, MC1
Kozlowski, T1
Dupuis, R1
Detwiler, R1
Lee, RM1
Deyo, JC1
Aksoy, D1
Cevik, B1
Kurt, S1
Pekdas, E1
Solmaz, V1
Watanabe, T2
Yoshikawa, H2
Yamazaki, S1
Abe, Y1
Abe, T2
Martuseviciene, G1
Kamper, AL1
Horn, T1
Jefferson, JW1
Sen, D1
Fukuda, Y2
Watanabe, H2
Ohtomo, Y2
Yabuta, K2
Preda, A1
Fazeli, A1
McKay, BG1
Bowers, MB1
Mazure, CM1
Hirano, K1
Tomino, Y1
Lin, CY1
Chiang, H1

Reviews

1 review available for valproic acid and Interstitial Nephritis

ArticleYear
Tubulo-interstitial nephritis caused by sodium valproate.
    Brain & development, 2002, Volume: 24, Issue:2

    Topics: Adolescent; Anticonvulsants; Biopsy; Epilepsy; Fanconi Syndrome; Female; Humans; Nephritis, Intersti

2002

Other Studies

10 other studies available for valproic acid and Interstitial Nephritis

ArticleYear
Management of corticosteroid-dependent eosinophilic interstitial nephritis: A case report.
    Medicine, 2021, Dec-17, Volume: 100, Issue:50

    Topics: Adrenal Cortex Hormones; Adult; Biopsy; Creatinine; Humans; Lacosamide; Male; Mycophenolic Acid; Nep

2021
Lithium use for bipolar disorder post renal transplant: is mood stabilization without toxicity possible?
    Transplantation, 2014, Feb-15, Volume: 97, Issue:3

    Topics: Biopsy; Bipolar Disorder; Cyclosporine; Female; Glomerular Filtration Rate; Humans; Kidney Transplan

2014
Hypokalemia and hypomagnesaemia related to levetiracetam use.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:11

    Topics: Adult; Anticonvulsants; Humans; Hypokalemia; Lamotrigine; Levetiracetam; Magnesium; Male; Nephritis,

2014
Secondary renal Fanconi syndrome caused by valproate therapy.
    Pediatric nephrology (Berlin, Germany), 2005, Volume: 20, Issue:6

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Fanconi Syndrome; Female; Humans; Kidney Disea

2005
[A severe case of interstitial nephritis caused by sodium valproate].
    Ugeskrift for laeger, 2006, Oct-23, Volume: 168, Issue:43

    Topics: Adult; Anticonvulsants; Humans; Kidney Transplantation; Male; Nephritis, Interstitial; Valproic Acid

2006
Manic depressive disorder and lithium over the decades: the very educational case of Mrs. L.
    The Journal of clinical psychiatry, 1994, Volume: 55, Issue:8

    Topics: Aged; Aged, 80 and over; Bipolar Disorder; Drug Administration Schedule; Electroconvulsive Therapy;

1994
Immunologically mediated chronic tubulo-interstitial nephritis caused by valproate therapy.
    Nephron, 1996, Volume: 72, Issue:2

    Topics: Anticonvulsants; Biopsy; Child; Complement C3; Fibrosis; Humans; Immunoglobulin G; Kidney; Male; Nep

1996
Lamotrigine as prophylaxis against steroid-induced mania.
    The Journal of clinical psychiatry, 1999, Volume: 60, Issue:10

    Topics: Adult; Anti-Inflammatory Agents; Antimanic Agents; Bipolar Disorder; Contraindications; Female; Huma

1999
[A case report of chronic tubulo-interstitial nephritis].
    Nihon Jinzo Gakkai shi, 1992, Volume: 34, Issue:10

    Topics: CD4 Antigens; Child; Complement C3; Fanconi Syndrome; Humans; Immunoglobulin G; Kidney; Male; Nephri

1992
Sodium-valproate-induced interstitial nephritis.
    Nephron, 1988, Volume: 48, Issue:1

    Topics: Child, Preschool; Complement C3; Female; Humans; Immunoglobulin G; Lymphocyte Activation; Nephritis,

1988