valproic acid has been researched along with Inappropriate ADH Syndrome in 7 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Inappropriate ADH Syndrome: A condition of HYPONATREMIA and renal salt loss attributed to overexpansion of BODY FLUIDS resulting from sustained release of ANTIDIURETIC HORMONES which stimulates renal resorption of water. It is characterized by normal KIDNEY function, high urine OSMOLALITY, low serum osmolality, and neurological dysfunction. Etiologies include ADH-producing neoplasms, injuries or diseases involving the HYPOTHALAMUS, the PITUITARY GLAND, and the LUNG. This syndrome can also be drug-induced.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We consider this episode of SIADH to be the result of a combination of factors including a weakness of the central nervous system and the long-term administration of VPA." | 1.31 | Contribution of sodium valproate to the syndrome of inappropriate secretion of antidiuretic hormone. ( Horiguchi, J; Ishino, H; Itoga, M; Kishi, T; Miyaoka, T; Seno, H, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Franco Hidalgo, S | 1 |
| Prieto de Paula, JM | 1 |
| Salado Valdivieso, I | 1 |
| Beers, E | 1 |
| van Puijenbroek, EP | 1 |
| Bartelink, IH | 1 |
| van der Linden, CM | 1 |
| Jansen, PA | 1 |
| Bève, E | 1 |
| Beck, E | 1 |
| Pinto, E | 1 |
| Ansseau, M | 1 |
| Tsuru, T | 1 |
| Akiyama, R | 1 |
| Kohashi, K | 1 |
| Okumura, K | 1 |
| Bavbek, N | 1 |
| Alkan, R | 1 |
| Uz, E | 1 |
| Kaftan, O | 1 |
| Akcay, A | 1 |
| Ikeda, K | 1 |
| Moriyasu, H | 1 |
| Yasaka, M | 1 |
| Oita, J | 1 |
| Yamaguchi, T | 1 |
| Miyaoka, T | 1 |
| Seno, H | 1 |
| Itoga, M | 1 |
| Kishi, T | 1 |
| Ishino, H | 1 |
| Horiguchi, J | 1 |
7 other studies available for valproic acid and Inappropriate ADH Syndrome
| Article | Year |
|---|---|
[Inadequate vasopressin secretion and valproate].
Topics: Aged, 80 and over; Antimanic Agents; Bipolar Disorder; Comorbidity; Humans; Hyponatremia; Inappropri | 2009 |
Syndrome of inappropriate antidiuretic hormone secretion (SIADH) or hyponatraemia associated with valproic Acid: four case reports from the Netherlands and a case/non-case analysis of vigibase.
Topics: Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Anticonvulsants; Databases, Factua | 2010 |
[Inappropriate antidiuretic hormone secretion induced by sodium valproate].
Topics: Antimanic Agents; Bipolar Disorder; Humans; Inappropriate ADH Syndrome; Male; Middle Aged; Valproic | 2010 |
[Case of a 13-year-old boy with hyponatremia due to lamotrigine-induced syndrome of inappropriate secretion of antidiuretic hormone].
Topics: Adolescent; Anticonvulsants; Drug Therapy, Combination; Humans; Hyponatremia; Inappropriate ADH Synd | 2012 |
Hyponatremia associated with sodium valproate in a 22-year-old male.
Topics: Adult; Anticonvulsants; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Valproic Acid | 2008 |
[Valproate related syndrome of inappropriate secretion of antidiuretic hormone (SIADH)--a case report].
Topics: Aged; Aged, 80 and over; Epilepsy; Humans; Inappropriate ADH Syndrome; Male; Valproic Acid | 1994 |
Contribution of sodium valproate to the syndrome of inappropriate secretion of antidiuretic hormone.
Topics: Diagnosis, Differential; Epilepsy, Tonic-Clonic; Humans; Hyponatremia; Inappropriate ADH Syndrome; M | 2001 |