valproic acid has been researched along with Hypoxia-Ischemia, Brain in 5 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Hypoxia-Ischemia, Brain: A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Here we studied the cytoprotective effect of lithium chloride and sodium valproate in the in vivo model of neonatal cerebral ischemia/hypoxia and analyzed the influence of these substances on the death of the major neurovascular unit components in experimental ischemia in vitro." | 7.83 | Protection of Neurovascular Unit Cells with Lithium Chloride and Sodium Valproate Prevents Brain Damage in Neonatal Ischemia/Hypoxia. ( Babenko, VA; Gulyaev, MV; Pevzner, IB; Pirogov, YA; Plotnikov, EY; Savchenko, ES; Silachev, DN; Sukhikh, GT; Zorov, DB; Zorova, LD, 2016) |
| "Here we studied the cytoprotective effect of lithium chloride and sodium valproate in the in vivo model of neonatal cerebral ischemia/hypoxia and analyzed the influence of these substances on the death of the major neurovascular unit components in experimental ischemia in vitro." | 3.83 | Protection of Neurovascular Unit Cells with Lithium Chloride and Sodium Valproate Prevents Brain Damage in Neonatal Ischemia/Hypoxia. ( Babenko, VA; Gulyaev, MV; Pevzner, IB; Pirogov, YA; Plotnikov, EY; Savchenko, ES; Silachev, DN; Sukhikh, GT; Zorov, DB; Zorova, LD, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, L | 1 |
| Ma, A | 1 |
| Wood, N | 1 |
| Ardern-Holmes, S | 1 |
| Yamamoto, A | 1 |
| Saito, Y | 1 |
| Oyama, Y | 1 |
| Watanabe, Y | 1 |
| Ikeda, A | 1 |
| Takayama, R | 1 |
| Ikeda, H | 1 |
| Takeshita, S | 1 |
| Takumi, I | 1 |
| Itai, T | 1 |
| Miyatake, S | 1 |
| Matsumoto, N | 1 |
| Silachev, DN | 1 |
| Plotnikov, EY | 1 |
| Babenko, VA | 1 |
| Savchenko, ES | 1 |
| Zorova, LD | 1 |
| Pevzner, IB | 1 |
| Gulyaev, MV | 1 |
| Pirogov, YA | 1 |
| Sukhikh, GT | 1 |
| Zorov, DB | 1 |
| Kabakus, N | 1 |
| Ay, I | 1 |
| Aysun, S | 1 |
| Söylemezoglu, F | 1 |
| Ozcan, A | 1 |
| Celasun, B | 1 |
| Williams, JA | 1 |
| Barreiro, CJ | 1 |
| Nwakanma, LU | 1 |
| Lange, MS | 1 |
| Kratz, LE | 1 |
| Blue, ME | 1 |
| Berrong, J | 1 |
| Patel, ND | 1 |
| Gott, VL | 1 |
| Troncoso, JC | 1 |
| Johnston, MV | 1 |
| Baumgartner, WA | 1 |
5 other studies available for valproic acid and Hypoxia-Ischemia, Brain
| Article | Year |
|---|---|
Vaccination management in an asymptomatic child with a novel SCN1A variant and family history of status epilepticus following vaccination: A case report on a potential new direction in personalised medicine.
Topics: Anticonvulsants; Clobazam; Enterovirus A, Human; Enterovirus Infections; Epilepsy; Fatal Outcome; Fe | 2020 |
Effect of total callosotomy on KCNQ2-related intractable epilepsy.
Topics: Carbamazepine; Child; Corpus Callosum; Drug Resistant Epilepsy; Electroencephalography; Female; Huma | 2020 |
Protection of Neurovascular Unit Cells with Lithium Chloride and Sodium Valproate Prevents Brain Damage in Neonatal Ischemia/Hypoxia.
Topics: Animals; Animals, Newborn; Brain Injuries; Hypoxia; Hypoxia-Ischemia, Brain; Lithium Chloride; Rats; | 2016 |
Protective effects of valproic acid against hypoxic-ischemic brain injury in neonatal rats.
Topics: Animals; Animals, Newborn; Anticonvulsants; Apoptosis; Disease Models, Animal; Dose-Response Relatio | 2005 |
Valproic acid prevents brain injury in a canine model of hypothermic circulatory arrest: a promising new approach to neuroprotection during cardiac surgery.
Topics: Animals; Apoptosis; Aspartic Acid; Behavior, Animal; Biomarkers; Brain; Brain Chemistry; Brain Damag | 2006 |