valproic acid has been researched along with Hypospermatogenesis in 4 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report on 2 cases of oligoasthenoteratozoospermia due to therapy with valproic acid, which had been given on account of mal grand epilepsy in both cases." | 1.27 | [Oligoasthenoteratozoospermia in valproic acid therapy]. ( Falker, G; Krause, W, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gates, JR | 1 |
| Hayashi, T | 1 |
| Yoshida, S | 1 |
| Yoshinaga, A | 1 |
| Ohno, R | 1 |
| Ishii, N | 1 |
| Yamada, T | 1 |
| Niwa, K | 1 |
| Kitagawa, Y | 1 |
| Yoshii, F | 1 |
| Shinohara, Y | 1 |
| Falker, G | 1 |
| Krause, W | 1 |
4 other studies available for valproic acid and Hypospermatogenesis
| Article | Year |
|---|---|
Epilepsy versus antiepileptic drugs and gonadal function in men.
Topics: Androstenedione; Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy, Generalized; Humans; | 2004 |
Improvement of oligoasthenozoospermia in epileptic patients on switching anti-epilepsy medication from sodium valproate to phenytoin.
Topics: Adult; Anticonvulsants; Epilepsy; Follow-Up Studies; Humans; Male; Oligospermia; Phenytoin; Sperm Co | 2005 |
[Oligospermia improved by switching an anticonvulsant from phenytoin to valproate].
Topics: Adult; Anticonvulsants; Humans; Male; Oligospermia; Phenytoin; Valproic Acid | 1996 |
[Oligoasthenoteratozoospermia in valproic acid therapy].
Topics: Adult; Dose-Response Relationship, Drug; Epilepsy, Tonic-Clonic; Humans; Infertility, Male; Male; Ol | 1988 |